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Journal Articles

Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Hematopoietic Stem Cells in JAK2 -Mutant Myeloproliferative Neoplasms

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-141643

Published: 2020

Journal Articles

Zinc-Dependent Homomultimerization of Mutant Calreticulin Is Required for MPN Pathogenesis

Jeanne F Rivera, BSc, April Joy Baral, MSc, Rachael Smyth, MSc, Fatima Nadat, PhD, Emma Burman, BSc, Ghadah Alameer, MSc, Sally A Boxall, PhD, Brian R Jackson, PhD, Ann Mullally, MD, Edwin Chen, PhD

Blood (2019) 134 (Supplement_1): 312.

https://doi.org/10.1182/blood-2019-124005

Published: 2019

Journal Articles

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Thiago Mantello Bianco, MSc, Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Priscila Santos Scheucher, PhD, Isabel Weinhäuser, MSc, Antonio Bruno Alves Silva, BSc, Cleide Lucia Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo M Rego, MD PhD, Fabiola Traina, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2019) 134 (Supplement_1): 2977.

https://doi.org/10.1182/blood-2019-131023

Published: 2019

Journal Articles

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Blood (2019) 134 (Supplement_1): 4202.

https://doi.org/10.1182/blood-2019-126164

Published: 2019

Journal Articles

Pregnancy Outcomes, Risk Factors, and Gestational Cell Count Trends in Pregnant Women with Essential Thrombocythemia and Polycythemia Vera

Chi-Joan How, MD, Orly Leiva, BS, Thomas Bogue, BS, Geoffrey Fell, MS, Mark Bustoros, MD, Nathan T. Connell, MD MPH, Jean M. Connors, MD, Irene M. Ghobrial, MD, Nancy Higgins, Nicholas A Jessop, David J. Kuter, Jennifer Lombardi Story, Ann Mullally, MD, Valentina Nardi, MD, Donna S Neuberg, ScD, Rachel Styles, BS, Jeffrey I. Zwicker, MD, Gabriela S. Hobbs, MD, Annemarie E Fogerty, MD

Blood (2019) 134 (Supplement_1): 4172.

https://doi.org/10.1182/blood-2019-127058

Published: 2019

Journal Articles

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Diego Antonio Pereira-Martins, MSc, Patrícia Vianna Bonini Palma, BSc, Josiane Lilian Schiavinato, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 4335.

https://doi.org/10.1182/blood-2018-99-115006

Published: 2018

Journal Articles

GPVI Intracellular Signaling Is Activated in Platelets from Patients with Essential Thrombocythemia

Gabriela S. Hobbs, MD, Vanessa Eldridge, MS, Richard M. Stone, MD, Martha Wadleigh, MD, David P. Steensma, MD, Gregory A. Abel, MD, Daniel J. DeAngelo, MD, Ann Mullally, MD, Renata Grozovsky, PhD

Blood (2017) 130 (Supplement 1): 1025.

https://doi.org/10.1182/blood.V130.Suppl_1.1025.1025

Published: 2017

Journal Articles

Functional and Molecular Basis of Thrombopoietin Receptor Activation By Mutant Calreticulin

Shannon Elf, PhD, Nouran Abdelfattah, MPhil, April Joy Baral, MSc, BSc, Danielle Beeson, Amy Ko, Natalie Florescu, Edwin Chen, PhD, Ann Mullally, MD

Blood (2017) 130 (Supplement 1): 382.

https://doi.org/10.1182/blood.V130.Suppl_1.382.382

Published: 2017

Journal Articles

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Izabela Aparecida Lopes, MSc, Priscila Santos Scheucher, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MDPhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2017) 130 (Supplement 1): 4221.

https://doi.org/10.1182/blood.V130.Suppl_1.4221.4221

Published: 2017

Journal Articles

Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

Ofir Wolach, MD, Rob S Sellar, MD, Kimberly Martinod, PhD, Marie E. McConkey, PhD, Alexander J. Silver, B.S., Ryan Chappell, Richard M. Stone, MD, Martha Wadleigh, MD, David P Steensma, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, MSN, ANPc, Rebekka K. Schneider, MD, Robert F. Padera, MD PhD, Ann Mullally, MD, Denisa D. Wagner, PhD, Benjamin L. Ebert, MD PhD

Blood (2016) 128 (22): 633.

https://doi.org/10.1182/blood.V128.22.633.633

Published: 2016

Journal Articles

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Adriana Queiroz Arantes, MD, Cristina Tavares Leal, MD, Cleide Araújo Silva, Priscila Santos Scheucher, PhD, Aglair Bergamo, Robert S. Welner, PhD, Daniel G. Tenen, MD, Ann Mullally, MD, Susumu Kobayashi, MD PhD, Eduardo Magalhaes Rego, PhD, Lorena Lobo Figueiredo-Pontes, MD, PhD

Blood (2015) 126 (23): 1637.

https://doi.org/10.1182/blood.V126.23.1637.1637

Published: 2015

Journal Articles

Physical Interaction Between Mutant Calreticulin and the Thrombopoietin Receptor Is Required for Hematopoietic Transformation

Shannon Elf, PhD, Nouran Abdelfattah, MPhil, Edwin Chen, PhD, Javier Perales-Patón, Emily Rosen, BS, Amy Ko, Fabian Peisker, Natalie Florescu, Silvia Giannini, PhD, Ofir Wolach, MD, Elizabeth A. Morgan, MD, Julie-Aurore Losman, MD, PhD, Rebekka K. Schneider, MD, Fatima Al-Shahrour, PhD, Ann Mullally, MD

Blood (2015) 126 (23): LBA-4.

https://doi.org/10.1182/blood.V126.23.LBA-4.LBA-4

Published: 2015

Journal Articles

Marked Hyperferritinemia Does Not Predict for Hemophagocytic Lymphohistiocytosis (HLH) in the Adult Population

Alison M Schram, MD, Ann Mullally, MD, Federico Campigotto, MS, Annemarie E Fogerty, MD, Elena Massarotti, MD, Donna S. Neuberg, ScD, Nancy Berliner, MD

Blood (2014) 124 (21): 4951.

https://doi.org/10.1182/blood.V124.21.4951.4951

Published: 2014

Journal Articles

Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing

Allegra M Lord, Kendell Clement, Rebekka K. Schneider, MD, McConkey Marie, PhD, Michelle C. Chen, Ross L. Levine, MD, Ann Mullally, MD, Naomi Galili, PhD, Abdullah Mahmood Ali, PhD, Azra Raza, MD, Rafael Bejar, MD PhD, Alexander Meissner, PhD, Benjamin L. Ebert, MDPhD

Blood (2014) 124 (21): 775.

https://doi.org/10.1182/blood.V124.21.775.775

Published: 2014

Journal Articles

The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Edwin Chen, PhD, Jong-Sook Ahn, PhD, Lawrence J Breyfogle, Anthony R Green, PhDFRCP FRCPath, Benjamin L. Ebert, MDPhD, Ann Mullally, MD

Blood (2014) 124 (21): 822.

https://doi.org/10.1182/blood.V124.21.822.822

Published: 2014

Journal Articles

Mutant Splicing Factor 3b Subunit 1 (SF3B1) Causes Dysregulated Erythropoiesis and a Stem Cell Disadvantage

Esther A. Obeng, MDPhD, Marie E. McConkey, PhD, Dean Campagna, Rebekka K. Schneider, MD, Michelle C. Chen, Paul J Schmidt, PhD, Ann Mullally, MD, Mark D. Fleming, MD DPhil, Benjamin L. Ebert, MD DPhil

Blood (2014) 124 (21): 828.

https://doi.org/10.1182/blood.V124.21.828.828

Published: 2014

Journal Articles

Hemophagocytic Lymphohistiocytosis: The Partners Healthcare Experience over the Past 8 Years

Alison M Schram, MD, Ann Mullally, MD, Annemarie E Fogerty, MD, Elena Massarotti, MD, Nancy Berliner, MD

Blood (2014) 124 (21): 4104.

https://doi.org/10.1182/blood.V124.21.4104.4104

Published: 2014

Journal Articles

IL3-Receptor Signaling Is Dispensable For The Generation and Maintenance Of Jak2V617F-Induced Myeloproliferative Neoplasm (MPN

Therese Vu, Claudia Bruedigam, Rebecca Austin, Catherine Paine-Kuhn, Hayley S. Ramshaw, PhD, Angel F. Lopez, MBBS, PhD, Geoff Hill, MD, Ann Mullally, MD, Steven W Lane, MD, PhD

Blood (2013) 122 (21): 2841.

https://doi.org/10.1182/blood.V122.21.2841.2841

Published: 2013

Journal Articles

Dysregulation Of Bcl2 Family Proteins Induced By JAK2 V617F Mutation Contributes To The Abnormal Expansion Of Neoplastic Initiating Cells

Lorena Lobo Figueiredo-Pontes, MD, PhD, Robert S Welner, PhD, Yuta Mishima, PhD, Mihoko Yamamoto, MS, Ann Mullally, MD, Daniel G. Tenen, MD, Susumu Kobayashi, MD, PhD

Blood (2013) 122 (21): 2852.

https://doi.org/10.1182/blood.V122.21.2852.2852

Published: 2013

Journal Articles

Tet2 Loss Accelerates The Myeloproliferative Neoplasm (MPN) Phenotype Of Jak2V617F Knockin Mice But Is Insufficient To Cause Leukemic Transformation

Edwin Chen, Lawrence J Breyfogle, Rebekka K. Schneider, MD, Luke Poveromo, BS, Ross L. Levine, MD, Benjamin L. Ebert, MD, PhD, Ann Mullally, MD

Blood (2013) 122 (21): 4095.

https://doi.org/10.1182/blood.V122.21.4095.4095

Published: 2013

NARROW

Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Hematopoietic Stem Cells in JAK2 -Mutant Myeloproliferative Neoplasms

Zinc-Dependent Homomultimerization of Mutant Calreticulin Is Required for MPN Pathogenesis

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Pregnancy Outcomes, Risk Factors, and Gestational Cell Count Trends in Pregnant Women with Essential Thrombocythemia and Polycythemia Vera

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

GPVI Intracellular Signaling Is Activated in Platelets from Patients with Essential Thrombocythemia

Functional and Molecular Basis of Thrombopoietin Receptor Activation By Mutant Calreticulin

Imbalance between Tolerant and Cytotoxic Functional Subsets of NK Cells in a JAK2 V617F Myeloproliferative Neoplasm Model

Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Physical Interaction Between Mutant Calreticulin and the Thrombopoietin Receptor Is Required for Hematopoietic Transformation

Marked Hyperferritinemia Does Not Predict for Hemophagocytic Lymphohistiocytosis (HLH) in the Adult Population

Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing

The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Mutant Splicing Factor 3b Subunit 1 (SF3B1) Causes Dysregulated Erythropoiesis and a Stem Cell Disadvantage

Hemophagocytic Lymphohistiocytosis: The Partners Healthcare Experience over the Past 8 Years

IL3-Receptor Signaling Is Dispensable For The Generation and Maintenance Of Jak2V617F-Induced Myeloproliferative Neoplasm (MPN

Dysregulation Of Bcl2 Family Proteins Induced By JAK2 V617F Mutation Contributes To The Abnormal Expansion Of Neoplastic Initiating Cells

Tet2 Loss Accelerates The Myeloproliferative Neoplasm (MPN) Phenotype Of Jak2V617F Knockin Mice But Is Insufficient To Cause Leukemic Transformation

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American Society of Hematology

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American Society of Hematology

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