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Journal Articles

A Synthetic Analogue of the Indigo Jeans Dye Tryptanthrin, NT1, Induces Apoptosis in Vitro, Ex Vivo and in Vivo in CD95-Dependent Manner in Pediatric Leukemia and Lymphoma Cells Sensitizing Malignant Cells to Cytostatic Drugs Via Downregulation of XIAP

Patrick Jesse, MD, Herbert Riepl, PhD, Thomas Wieder, PhD, Guenter Henze, MD, Aram Prokop, MD, PhD

Blood (2008) 112 (11): 2630.

https://doi.org/10.1182/blood.V112.11.2630.2630

Published: 2008

Journal Articles

Apoptosis Induced by Extracts of Helleborus Niger in Different Lymphoma and Leukemia Cell Lines and Primary Lymphoblasts of Children with ALL Is Independent of Smac-Overexpression and Executed Via the Mitochondrial Pathway.

Patrick Jesse, Gritt Mottke, Georg Seifert, Simone Fulda, MD, Guenter Henze, MD, Aram Prokop, PhD MD

Blood (2007) 110 (11): 4215.

https://doi.org/10.1182/blood.V110.11.4215.4215

Published: 2007

Journal Articles

Carbonyl-Substituted Titanocenes as New Cytostatic Agents Against Lymphoma and Leukemia in Childhood.

Anja Selig, Laura Wagner, Iris Winkler, Thorsten Lauterbach, PhD, Andreas Gansaeuer, PhD, Aram Prokop, PhD, MD

Blood (2007) 110 (11): 4208.

https://doi.org/10.1182/blood.V110.11.4208.4208

Published: 2007

Journal Articles

Effective Induction of Apoptosis by Mistletoe Plant Extracts in an Acute Lymphoblastic Leukemia Model.

Georg Seifert, MD, Patrick Jesse, MD, Aram Prokop, PhD, Tobias Reindl, MD, Stephan Lobitz, MD, Alfred Laengler, MD, Holger N. Lode, PhD, Guenter Henze, PhD

Blood (2006) 108 (11): 1880.

https://doi.org/10.1182/blood.V108.11.1880.1880

Published: 2006

Journal Articles

New Pinostilbene Analogues Overcome Anthracycline Resistance in Acute Lymphoplastic Leukemia Ex Vivo .

Banu Katik, Anja Selig, Janna Velder, PhD, Elvira E. Shults, PhD, Thomas Wieder, PhD, Guenter Henze, MD, Hans-Guenther Schmalz, PhD, Aram Prokop, MD, PhD

Blood (2006) 108 (11): 4403.

https://doi.org/10.1182/blood.V108.11.4403.4403

Published: 2006

Journal Articles

Ferrocenyl Nucleoside Analogs, a New Class of Cytostatic Drugs, Overcome Multiple Drug Resistance in Acute Lymphoplastic Leukemia Ex Vivo .

Aram Prokop, MD, PhD, Moritz Eissmann, Patrick Jesse, Guenter Henze, MD, Philippe James, PhD, Joerg Neudoerfl, Hans-Guenther Schmalz, PhD

Blood (2006) 108 (11): 4404.

https://doi.org/10.1182/blood.V108.11.4404.4404

Published: 2006

Journal Articles

Copper-Complexed Melphalan (MOC*M), a Member of a New Class of Anti-Leukemic and Anti-Tumouric Substances for Treatment of Primary and Relapsed Acute Lymphoblastic Leukemia in Childhood.

Aram Prokop, MD, PhD, Corazon Frias, Guenter Henze, MD, Swetlana Sadolinnaya, PhD, Valeriy Tatarskiy, PhD

Blood (2005) 106 (11): 4457.

https://doi.org/10.1182/blood.V106.11.4457.4457

Published: 2005

Journal Articles

Sensitivity of Childhood Acute Lymphoblastic Leukemia (ALL) to Idarubicin Is Significantly Higher Than to Daunorubicin Treatment Based on Ex Vivo Apoptosis Induction.

Aram Prokop, MD, PhD, Banu Bagci, Guenaelle Lingfeld, MD, Lucia Badiali, Karin Garbrecht, Ulrike Mietzsch, MD, Thomas Wieder, PhD, Peter T. Daniel, MD, Günter Henze, MD

Blood (2004) 104 (11): 4495.

https://doi.org/10.1182/blood.V104.11.4495.4495

Published: 2004

Journal Articles

Iron Containing Nucleosides as New Cytostatic Substances for Cancer and Leukemia Therapy, Especially for Therapy of Relapsed ALL in Childhoodtransfusion of Red Blood Cells under Shock Conditions in the Rat Microvasculature.

Aram Prokop, MD, PhD, Thomas Wieder, PhD, Daniel Schlawe, PhD, Holger Lode, MD, Guenter Henze, MD, Peter T. Daniel, MD, Hans G. Schmalz, PhD

Blood (2004) 104 (11): 2085.

https://doi.org/10.1182/blood.V104.11.2085.2085

Published: 2004

Journal Articles

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3

Thomas Wieder, Frank Essmann, Aram Prokop, Karin Schmelz, Klaus Schulze-Osthoff, Rudi Beyaert, Bernd Dörken, Peter T. Daniel

Blood (2001) 97 (5): 1378–1387.

https://doi.org/10.1182/blood.V97.5.1378

Published: 2001

NARROW

A Synthetic Analogue of the Indigo Jeans Dye Tryptanthrin, NT1, Induces Apoptosis in Vitro, Ex Vivo and in Vivo in CD95-Dependent Manner in Pediatric Leukemia and Lymphoma Cells Sensitizing Malignant Cells to Cytostatic Drugs Via Downregulation of XIAP

Apoptosis Induced by Extracts of Helleborus Niger in Different Lymphoma and Leukemia Cell Lines and Primary Lymphoblasts of Children with ALL Is Independent of Smac-Overexpression and Executed Via the Mitochondrial Pathway.

Carbonyl-Substituted Titanocenes as New Cytostatic Agents Against Lymphoma and Leukemia in Childhood.

Effective Induction of Apoptosis by Mistletoe Plant Extracts in an Acute Lymphoblastic Leukemia Model.

New Pinostilbene Analogues Overcome Anthracycline Resistance in Acute Lymphoplastic Leukemia Ex Vivo .

Ferrocenyl Nucleoside Analogs, a New Class of Cytostatic Drugs, Overcome Multiple Drug Resistance in Acute Lymphoplastic Leukemia Ex Vivo .

Copper-Complexed Melphalan (MOC*M), a Member of a New Class of Anti-Leukemic and Anti-Tumouric Substances for Treatment of Primary and Relapsed Acute Lymphoblastic Leukemia in Childhood.

Sensitivity of Childhood Acute Lymphoblastic Leukemia (ALL) to Idarubicin Is Significantly Higher Than to Daunorubicin Treatment Based on Ex Vivo Apoptosis Induction.

Iron Containing Nucleosides as New Cytostatic Substances for Cancer and Leukemia Therapy, Especially for Therapy of Relapsed ALL in Childhoodtransfusion of Red Blood Cells under Shock Conditions in the Rat Microvasculature.

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3

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American Society of Hematology

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