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Journal Articles

BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis

Blood (2023) 142 (13): 1143–1155.

https://doi.org/10.1182/blood.2022019274

Published: 2023

Includes: Supplemental data

Journal Articles

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Blood (2021) 138 (10): 871–884.

https://doi.org/10.1182/blood.2020009404

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma

Philip Bucher, Tabea Erdmann, Paula Grondona, Wendan Xu, Anja Schmitt, Christoph Schürch, Myroslav Zapukhlyak, Caroline Schönfeld, Edgar Serfling, Daniela Kramer, Michael Grau, Pavel Klener, Claudia Lengerke, Klaus Schulze-Osthoff, Georg Lenz, Stephan Hailfinger

Blood (2020) 135 (2): 121–132.

https://doi.org/10.1182/blood.2019001866

Published: 2020

Includes: Supplemental data

Journal Articles

Impaired DNA Damage Repair in Severe Congenital Neutropenia Patients

Perihan Mir, Maksim Klimiankou, PhD, Benjamin Dannenmann, Cornelia Zeidler, MD, Klaus Schulze-Osthoff, PhD, Lothar Kanz, MD, Karl Welte, MD, Julia Skokowa, MD PhD

Blood (2016) 128 (22): 1334.

https://doi.org/10.1182/blood.V128.22.1334.1334

Published: 2016

Journal Articles

Platelets induce apoptosis via membrane-bound FasL

Blood (2015) 126 (12): 1483–1493.

https://doi.org/10.1182/blood-2013-12-544445

Published: 2015

Includes: Supplemental data

Journal Articles

EVI-1 Mediates Apoptosis Resistance Via CD261 Induction and Enhances Leukemogenic Potential in Human Acute Lymphoblastic Leukemia

Martina Konantz, PhD, Maya Caroline Andre, MD, Martin Ebinger, MD, Matthias Grauer, Hui Wang, Sarah Grzywna, Helmut R. Salih, MD, Rupert Handgretinger, MD, Olga S. Kustikova, PhD, Christopher Baum, MD, Lothar Kanz, MD, Klaus Schulze-Osthoff, PhD, Leticia Quintanilla-Martinez, MD, Frank Essmann, PhD, Claudia Lengerke, MD

Blood (2011) 118 (21): 1356.

https://doi.org/10.1182/blood.V118.21.1356.1356

Published: 2011

Journal Articles

A single nucleotide polymorphism determines protein isoform production of the human c-FLIP protein

Nana Ueffing, Kusum K. Singh, Andrea Christians, Christoph Thorns, Alfred C. Feller, Florian Nagl, Falko Fend, Sebastian Heikaus, Alexander Marx, Rainer B. Zotz, Joachim Brade, Wolfgang A. Schulz, Klaus Schulze-Osthoff, Ingo Schmitz, Christian Schwerk

Blood (2009) 114 (3): 572–579.

https://doi.org/10.1182/blood-2009-02-204230

Published: 2009

Includes: Supplemental data

Journal Articles

Up-regulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells

Nana Ueffing, Marc Schuster, Eric Keil, Klaus Schulze-Osthoff, Ingo Schmitz

Blood (2008) 112 (3): 690–698.

https://doi.org/10.1182/blood-2008-02-141382

Published: 2008

Includes: Supplemental data

Journal Articles

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment

Katja Janssen, Stephan Pohlmann, Reiner U. Jänicke, Klaus Schulze-Osthoff, Ute Fischer

Blood (2007) 110 (10): 3662–3672.

https://doi.org/10.1182/blood-2007-02-073213

Published: 2007

Includes: Supplemental data

Journal Articles

Up-regulation of c-FLIP S+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL

Anja Troeger, Ingo Schmitz, Meinolf Siepermann, Ludmila Glouchkova, Ulrike Gerdemann, Gritta E. Janka-Schaub, Klaus Schulze-Osthoff, Dagmar Dilloo

Blood (2007) 110 (1): 384–387.

https://doi.org/10.1182/blood-2006-08-038398

Published: 2007

Journal Articles

MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program

Dorothee Viemann, Katarzyna Barczyk, Thomas Vogl, Ute Fischer, Cord Sunderkötter, Klaus Schulze-Osthoff, Johannes Roth

Blood (2006) 109 (6): 2453–2460.

https://doi.org/10.1182/blood-2006-08-040444

Published: 2006

Journal Articles

Upregulation of FLIPs upon CD40 Stimulation - A Novel Inhibititory Mechanism of CD95-Induced Apoptosis in Precursor B-ALL Blasts in Children.

Anja Troeger, Ingo Schmitz, Ludmila Glouchkova, Meinolf Siepermann, Gritta Janka-Schaub, Klaus Schulze-Osthoff, Dagmar Dilloo

Blood (2005) 106 (11): 855.

https://doi.org/10.1182/blood.V106.11.855.855

Published: 2005

Journal Articles

Arsenic Trioxide Induces Regulated, Death Receptor- and Caspase-Independent Cell Death through the Mitochondrial Death Pathway.

Christian Scholz, MD, Antje Richter, Mario Lehmann, Klaus Schulze-Osthoff, MD, Bernd Dörken, MD, Peter T. Daniel, MD

Blood (2005) 106 (11): 4421.

https://doi.org/10.1182/blood.V106.11.4421.4421

Published: 2005

Journal Articles

Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo

Andrea Renz, Wolfgang E. Berdel, Michael Kreuter, Claus Belka, Klaus Schulze-Osthoff, Marek Los

Blood (2001) 98 (5): 1542–1548.

https://doi.org/10.1182/blood.V98.5.1542

Published: 2001

Journal Articles

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3

Thomas Wieder, Frank Essmann, Aram Prokop, Karin Schmelz, Klaus Schulze-Osthoff, Rudi Beyaert, Bernd Dörken, Peter T. Daniel

Blood (2001) 97 (5): 1378–1387.

https://doi.org/10.1182/blood.V97.5.1378

Published: 2001

Journal Articles

Anticancer Drugs Induce Caspase-8/FLICE Activation and Apoptosis in the Absence of CD95 Receptor/Ligand Interaction

Sebastian Wesselborg, Ingo H. Engels, Evi Rossmann, Marek Los, Klaus Schulze-Osthoff

Blood (1999) 93 (9): 3053–3063.

https://doi.org/10.1182/blood.V93.9.3053

Published: 1999

Journal Articles

Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases)

Marek Los, Ingrid Herr, Claudia Friesen, Simone Fulda, Klaus Schulze-Osthoff, Klaus-Michael Debatin

Blood (1997) 90 (8): 3118–3129.

https://doi.org/10.1182/blood.V90.8.3118

Published: 1997

NARROW

BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma

Impaired DNA Damage Repair in Severe Congenital Neutropenia Patients

Platelets induce apoptosis via membrane-bound FasL

EVI-1 Mediates Apoptosis Resistance Via CD261 Induction and Enhances Leukemogenic Potential in Human Acute Lymphoblastic Leukemia

A single nucleotide polymorphism determines protein isoform production of the human c-FLIP protein

Up-regulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment

Up-regulation of c-FLIP S+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL

MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program

Upregulation of FLIPs upon CD40 Stimulation - A Novel Inhibititory Mechanism of CD95-Induced Apoptosis in Precursor B-ALL Blasts in Children.

Arsenic Trioxide Induces Regulated, Death Receptor- and Caspase-Independent Cell Death through the Mitochondrial Death Pathway.

Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3

Anticancer Drugs Induce Caspase-8/FLICE Activation and Apoptosis in the Absence of CD95 Receptor/Ligand Interaction

Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases)

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American Society of Hematology

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American Society of Hematology

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