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Journal Articles

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136294

Published: 2020

Journal Articles

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

Lisa Maria Kuhn, Cyrill Schipp, PhD, Daniel Hein, PhD, Bianca Killing, Nan Qin, PhD, Vera H Jepsen, M.Sc., Heinz Ahlert, MSc, BSc, Jasmin Bartl, PhD, Viktoria Marquardt, M.Sc., David Pauck, Kai Völtzke, M.Sc., Jonathan Lim, PhD, Gabriel Leprivier, PhD, Marc Remke, MD, Sanil Bhatia, PhD, Thorsten Rosenbaum, MD, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2019) 134 (Supplement_1): 4651.

https://doi.org/10.1182/blood-2019-131406

Published: 2019

Journal Articles

Hematological Presentation and Change in Clinical Phenotype during Follow-up in Pearson Syndrome

Ayami Yoshimi, MD PhD, Sarah C Grünert, MD, Holger Cario, MD PhD, Ute Gross-Wieltsch, MD, Udo Kontny, MD, Kyogo Suzuki, MD PhD, Stephan Lobitz, MD, Helen Wagner, MD, Irene Schmid, MD, Daniela Karall, MD, Arndt Borkhardt, MD, Miriam Erlacher, Peter Noellke, MPH, Charlotte M. Niemeyer, MD

Blood (2019) 134 (Supplement_1): 3746.

https://doi.org/10.1182/blood-2019-125199

Published: 2019

Journal Articles

Therapeutic Stratification of PTEN-MYC Axis Appears to be Promising for Molecular Targeted Therapies in Refractory and Relapsed T-Cell Acute Lymphoblastic Leukemia

Heinz Ahlert, MSc, BSc, Sanil Bhatia, PhD, Marc Remke, MD, Melf Sönnichsen, M.Sc., Niklas Dienstbier, M.Sc., Ute Fischer, PhD, Julia Hauer, MD, Arndt Borkhardt, MD

Blood (2019) 134 (Supplement_1): 3883.

https://doi.org/10.1182/blood-2019-128136

Published: 2019

Journal Articles

Family Trio-Based Whole Genome Optical Mapping Identifies Candidate Structural Variations Predisposing Children to Acute Lymphoblastic Leukemia

Ute Fischer, PhD, Layal Yasin, PhD, Julia Täubner, PhD, Triantafyllia Brozou, MD, Arndt Borkhardt, MD

Blood (2019) 134 (Supplement_1): 5201.

https://doi.org/10.1182/blood-2019-130014

Published: 2019

Journal Articles

A Tumor Suppressor Role for Bank1 in B-Cell Precursor Acute Lymphoblastic Leukemia

Franziska Auer, PhD, Rodríguez-Hernández Guillermo, M.Sc., Inés González-Herrero, PhD, Oscar Blanco, MDPhD, Diego Alonso-López, PhD, Javier De Las Rivas, PhD, Rafael Jimenez, PhD, Francisco J. García-Criado, PhD, Maria B. García-Cenador, PhD, Carolina Vicente-Dueñas, PhD, Arndt Borkhardt, MD, Isidro Sanchez-Garcia, PhD, Julia Hauer, MD

Blood (2018) 132 (Supplement 1): 1333.

https://doi.org/10.1182/blood-2018-99-115281

Published: 2018

Journal Articles

Therapeutic Targeting of HSP90 in AML and ALL

Sanil Bhatia, PhD, Heinz Ahlert, Msc, Benedikt Frieg, PhD, Arndt Borkhardt, MD, Holger Gohlke, PhD, Thomas Kurz, Julia Hauer, MD

Blood (2018) 132 (Supplement 1): 4680.

https://doi.org/10.1182/blood-2018-99-120362

Published: 2018

Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD

Blood (2018) 132 (Supplement 1): 566.

https://doi.org/10.1182/blood-2018-99-115913

Published: 2018

Journal Articles

Novel Recurrent Germline JAK2 G571S Variant in Childhood Acute B-Lymphoblastic Leukemia: A Double Hit One Pathway Scenario

Franziska Auer, PhD, Minhui Lin, PhD, Karin Nebral, PhD, Christoph G. W. Gertzen, PhD, Oskar A. Haas, MD, Michaela Kuhlen, MD, Holger Gohlke, PhD, Shai Izraeli, MD, Jan Trka, MD PhD, Jianda Hu, PhD, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2018) 132 (Supplement 1): 387.

https://doi.org/10.1182/blood-2018-99-115293

Published: 2018

Journal Articles

Determination of the Origin of the t(1;19) TCF3-PBX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Hein, PhD, Karin Dreisig, PhD, Shai Izraeli, MD, Kjeld Schmiegelow, MD, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2018) 132 (Supplement 1): 4093.

https://doi.org/10.1182/blood-2018-99-110521

Published: 2018

Journal Articles

Activation Induced Cytidine Deaminase (Aid) Acts As a Gate Keeper in Pro-B Cells and Prevents PB-ALL

Franziska Auer, MSc, Deborah Ingenhag, MSc, Isidro Sánchez-García, MD, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2016) 128 (22): 1538.

https://doi.org/10.1182/blood.V128.22.1538.1538

Published: 2016

Journal Articles

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Deborah Ingenhag, MSc, Franziska Auer, MSc, Arndt Borkhardt, MD, Julia Hauer, MD

Blood (2016) 128 (22): 1539.

https://doi.org/10.1182/blood.V128.22.1539.1539

Published: 2016

Journal Articles

Nucleolin Controls Ribosome Biogenesis through Its RNA-Binding Properties

Julia Fremerey, PhD, Pavel Morozov, PhD, Cindy Meyer, PhD, Aitor Garzia, PhD, Marianna Teplova, PhD, Thomas Tuschl, PhD, Arndt Borkhardt, MD

Blood (2016) 128 (22): 5056.

https://doi.org/10.1182/blood.V128.22.5056.5056

Published: 2016

Journal Articles

Identifying Possible Candidate Factors Influencing the Penetrance of Heterozygous NFKB1 Loss of Function Mutations By Whole Exome Sequencing

Cyrill Schipp, MSc, Arndt Borkhardt, MD, Polina Stepensky, MD, Ute Fischer, PhD

Blood (2016) 128 (22): 3706.

https://doi.org/10.1182/blood.V128.22.3706.3706

Published: 2016

Journal Articles

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia Relapsing after Allogeneic Stem Cell Transplantation

Jessica I Hoell, MD, Sebastian Ginzel, MSc, Cornelia Eckert, PhD, Michael Gombert, PhD, Ute Fischer, PhD, Martin Stanulla, MD, Martin Schrappe, MD PhD, Udo zur Stadt, PhD, Peter Bader, MD, Brigitte Strahm, MD, Julia Alten, Anja Moericke, MD, Gabriele Escherich, MD, Arend Stackelberg, MD, Christina Peters, MD, Arndt Borkhardt, MD, Roland Meisel, MD

Blood (2016) 128 (22): 601.

https://doi.org/10.1182/blood.V128.22.601.601

Published: 2016

Journal Articles

Palliative Outpatient Care in Children with Hematologic Malignancies Compared to Solid Tumors

Michaela Kuhlen, MD, Jessica I Hoell, MD, Gabriele Gagnon, MD, Stefan Balzer, MD, Arndt Borkhardt, MD, Gisela Janßen, MD

Blood (2016) 128 (22): 5977.

https://doi.org/10.1182/blood.V128.22.5977.5977

Published: 2016

Journal Articles

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Schaefer, MSc, Marianne Olsen, MD, Ulrik Lausten-Thomsen, MD PhD, Cyrill Schipp, MSc, Martin Stanulla, MD, Robert K. Slany, PhD, Kjeld Schmiegelow, MD DMSc, Arndt Borkhardt, MD, Ute Fischer, PhD

Blood (2016) 128 (22): 4082.

https://doi.org/10.1182/blood.V128.22.4082.4082

Published: 2016

Journal Articles

Activating Mutation of STAT3 Protects Lymphocytes from Apoptosis and Leads to a Clinical Phenotype Resembling the Autoimmune Lymphoproliferative Syndrome

Schafiq Nabhani, PhD, Hagit Miskin, MD, Cyrill Schipp, MSc, Dan Harlev, Shoshana Revel-Vilk, MD MSc, Michael Gombert, PhD, Sebastian Ginzel, MSc, Arndt Borkhardt, MD, Polina Stepensky, MD, Ute Fischer, PhD

Blood (2015) 126 (23): 2218.

https://doi.org/10.1182/blood.V126.23.2218.2218

Published: 2015

Journal Articles

Identification of Blut, a Novel Long-Noncoding RNA Differentially Expressed in Burkitt Lymphoma

Blood (2015) 126 (23): 3875.

https://doi.org/10.1182/blood.V126.23.3875.3875

Published: 2015

Journal Articles

A New ETV6-RUNX1 In Vivo Model Produces a Phenocopy of the Human Pb-ALL

Blood (2015) 126 (23): 3658.

https://doi.org/10.1182/blood.V126.23.3658.3658

Published: 2015

NARROW

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

Hematological Presentation and Change in Clinical Phenotype during Follow-up in Pearson Syndrome

Therapeutic Stratification of PTEN-MYC Axis Appears to be Promising for Molecular Targeted Therapies in Refractory and Relapsed T-Cell Acute Lymphoblastic Leukemia

Family Trio-Based Whole Genome Optical Mapping Identifies Candidate Structural Variations Predisposing Children to Acute Lymphoblastic Leukemia

A Tumor Suppressor Role for Bank1 in B-Cell Precursor Acute Lymphoblastic Leukemia

Therapeutic Targeting of HSP90 in AML and ALL

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Novel Recurrent Germline JAK2 G571S Variant in Childhood Acute B-Lymphoblastic Leukemia: A Double Hit One Pathway Scenario

Determination of the Origin of the t(1;19) TCF3-PBX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Activation Induced Cytidine Deaminase (Aid) Acts As a Gate Keeper in Pro-B Cells and Prevents PB-ALL

HB9 Represses Hematopoietic Stem Cell Proliferation and Induces Senescence

Nucleolin Controls Ribosome Biogenesis through Its RNA-Binding Properties

Identifying Possible Candidate Factors Influencing the Penetrance of Heterozygous NFKB1 Loss of Function Mutations By Whole Exome Sequencing

Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia Relapsing after Allogeneic Stem Cell Transplantation

Palliative Outpatient Care in Children with Hematologic Malignancies Compared to Solid Tumors

2% of Healthy Newborns Reveal ETV6-RUNX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Activating Mutation of STAT3 Protects Lymphocytes from Apoptosis and Leads to a Clinical Phenotype Resembling the Autoimmune Lymphoproliferative Syndrome

Identification of Blut, a Novel Long-Noncoding RNA Differentially Expressed in Burkitt Lymphoma

A New ETV6-RUNX1 In Vivo Model Produces a Phenocopy of the Human Pb-ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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