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Journal Articles

Impact of Novel M-Component Based Biomarkers On to Progression Free Survival After Treatment in Intact Immunoglobulin Multiple Myeloma.

Efstathios Koulieris, Dimitrios Maltezas, Nikolaou Eytychia, Vassiliki Bartzis, Tatianna Tzenou, Vassiliki Karali, Pessach Ilias, Katerina Sarris, Stephen Harding, Arthur Bradwell, FRCP, FRCPath, Theodoros P. Vassilakopoulos, Maria K. Angelopoulou, Nikolitsa Kafasi, Panayiotis Panayiotidis, Marie-Christine Kyrtsonis

Blood (2012) 120 (21): 2927.

https://doi.org/10.1182/blood.V120.21.2927.2927

Published: 2012

Journal Articles

Heavy Chain Ratio (HLCR) IgGκ/IgGλ or IgAκ/IgAλ: Experience and Clinical Implications In Multiple Myeloma at Diagnosis and During Disease Course

Efstathios Koulieris, Marie-Christine Kyrtsonis, Nikolitsa Kafassi, Dimitris Maltezas, Vassiliki Bartzis, Tatiana Tzenou, Maria Dimou, George Georgiou, Ladan Mirbahai, Panayiotis Panayiotidis, Arthur Bradwell, FRCP, FRCPath, Stephen Harding, PhD

Blood (2010) 116 (21): 5019.

https://doi.org/10.1182/blood.V116.21.5019.5019

Published: 2010

Journal Articles

Non-Clonal Serum Immunoglobulin Free Light Chains (FLC) as Markers of Overall Survival

Angela Dispenzieri, M.D., Robert Kyle, MD, Jerry A Katzmann, PhD, Dirk Larson, Shaji Kumar, MD, Graham Peter Mead, PhD, Arthur Bradwell, FRCP, FRCPath, S. Vincent Rajkumar, MD

Blood (2010) 116 (21): 3893.

https://doi.org/10.1182/blood.V116.21.3893.3893

Published: 2010

Journal Articles

The Ratio of Monoclonal to Polyclonal Immunoglobulins Assessed with the Hevylite Test Predicts Prognosis, Is Superior for Monitoring the Course of the Disease and Allows Detection of Monoclonal Immunoglobulin In Patients with Normal or Subnormal Involved Immunoglobulin Isotype

Heinz Ludwig, MD, Ladan Mirbahai, Niklas Zojer, PhD, MD, Arthur Bradwell, FRCP, FRCPath, Stephen Harding, PhD

Blood (2010) 116 (21): 4038.

https://doi.org/10.1182/blood.V116.21.4038.4038

Published: 2010

Journal Articles

Quantification of Serum IgMκ and IgMλ In Patients with Waldenstrom's Macroglobulinemia (WM) at Diagnosis and During Disease Course; Clinical Correlations

Efstathios Koulieris, Marie-Christine Kyrtsonis, Dimitris Maltezas, Tatiana Tzenou, Ladan Mirbahai, Nikolitsa Kafassi, Vassiliki Bartzis, Maria Dimou, George Georgiou, Charis Matsouka, Gerasimos Pangalis, Panayiotis Panayiotidis, Arthur Bradwell, FRCP, FRCPath, Stephen Harding, PhD

Blood (2010) 116 (21): 3004.

https://doi.org/10.1182/blood.V116.21.3004.3004

Published: 2010

Journal Articles

Heavy/Light Chain Specific Immunoglobulin Ratios at Presentation Are Prognostic for Progression Free Survival in the IFM 2005-01 Myeloma Trial.

Herve AvetLoiseau, MD, Jean-Luc Harousseau, Philippe Moreau, MD, Claire Mathiot, Thierry Facon, Michel Attal, MD, Arthur Bradwell, FRCP, FRCPath, Stephen Harding, PhD

Blood (2009) 114 (22): 1818.

https://doi.org/10.1182/blood.V114.22.1818.1818

Published: 2009

Journal Articles

Isotype-Specific Heavy/Light Chain (HLC) Suppression as a Predictor of Myeloma Development in Monoclonal Gammopathy of Undetermined Significance (MGUS).

Jerry Katzmann, PhD, Raynell Clark, Angela Dispenzieri, M.D., Robert Kyle, MD, Ola Landgren, M.D., Ph.D., Arthur Bradwell, FRCP, FRCPath, S. Vincent Rajkumar, MD

Blood (2009) 114 (22): 1788.

https://doi.org/10.1182/blood.V114.22.1788.1788

Published: 2009

Journal Articles

Serum FLC Levels at Presentation Have Independent Prognostic Significance in CLL and Levels Above 50mg/L Identify Patients with Progressive Disease.

Guy Pratt, Stephen Harding, PhD, Chris Fegan, Chris J Pepper, David Oscier, Anne Gardiner, Roger Holder, Arthur Bradwell, FRCP, FRCPath, Graham Mead, PhD

Blood (2009) 114 (22): 2355.

https://doi.org/10.1182/blood.V114.22.2355.2355

Published: 2009

Journal Articles

A New Staging System for AL Amyloidosis Incorporating Serum Free Light Chains, cardiac Troponin-T and NT-ProBNP.

Ashutosh D Wechalekar, Nancy L Wassef, Simon DJ Gibbs, Julian Gillmore, Felicia Dike, Helen Lachmann, Prayman Sattianayagam, Arthur Bradwell, Philip N Hawkins

Blood (2009) 114 (22): 2796.

https://doi.org/10.1182/blood.V114.22.2796.2796

Published: 2009

Journal Articles

Abnormal Serum IgA Kappa / IgA Lambda Ratios at Maximum Response Predict Poor Progression Free Survival in Myeloma Patients.

Heinz Ludwig, MD, Stephen Harding, PhD, Caroline Bradley, Dejan Milosavljevich, Mark T Drayson, Gareth J Morgan, J. Anthony Child, Arthur Bradwell, FRCP, FRCPath

Blood (2009) 114 (22): 4879.

https://doi.org/10.1182/blood.V114.22.4879.4879

Published: 2009

Journal Articles

Serum Free Light Chain and Serum Heavy / Light Chain Ratios Are Independently Prognostic in Multiple Myeloma Patients.

Efstathios Koulieris, Stephen Harding, PhD, Marie-Christine Kyrtsonis, Caroline Bradley, Mark T Drayson, Gareth J Morgan, J. Anthony Child, Arthur Bradwell, FRCP, FRCPath

Blood (2009) 114 (22): 4880.

https://doi.org/10.1182/blood.V114.22.4880.4880

Published: 2009

Journal Articles

Association of High Levels of Free Light Chain and the Presence of Igh Translocations in Multiple Myeloma and Prognostic Implications.

Shaji Kumar, Lijun Zhang, Angela Dispenzieri, Scott Van Wier, Jerry Katzmann, Melissa Snyder, Emily Blood, Roberta DeGoey, Kim Henderson, Arthur Bradwell, Robert Kyle, Philip Greipp, S. Vincent Rajkumar, Rafael Fonseca

Blood (2008) 112 (11): 1677.

https://doi.org/10.1182/blood.V112.11.1677.1677

Published: 2008

Journal Articles

AL amyloidosis associated with IgM paraproteinemia: clinical profile and treatment outcome

Ashutosh D. Wechalekar, Helen J. Lachmann, Hugh J. B. Goodman, Arthur Bradwell, Philip N. Hawkins, Julian D. Gillmore

Blood (2008) 112 (10): 4009–4016.

https://doi.org/10.1182/blood-2008-02-138156

Published: 2008

Journal Articles

Combined Chemotherapy and High Cut-Off Hemodialysis Improve Outcomes in Multiple Myeloma Patients with Severe Renal Failure.

Colin A. Hutchison, Mark Cook, Supratik Basu, Paul Cockwell, Kolitha Basnayake, Arthur Bradwell

Blood (2007) 110 (11): 3610.

https://doi.org/10.1182/blood.V110.11.3610.3610

Published: 2007

Journal Articles

Prevalence of Light-Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS) among Olmsted County, Minnesota Residents Aged 50 Years or Greater.

S. Vincent Rajkumar, MD, Robert Kyle, MD, Matthew Plevak, BS, Raynell Clark, Dirk Larson, MS, Terry Therneau, PhD, Arthur Bradwell, MB ChB, Angela Dispenzieri, MD, L. Joseph Melton, III, MD, Jerry Katzmann, PhD

Blood (2006) 108 (11): 5060.

https://doi.org/10.1182/blood.V108.11.5060.5060

Published: 2006

NARROW

Impact of Novel M-Component Based Biomarkers On to Progression Free Survival After Treatment in Intact Immunoglobulin Multiple Myeloma.

Heavy Chain Ratio (HLCR) IgGκ/IgGλ or IgAκ/IgAλ: Experience and Clinical Implications In Multiple Myeloma at Diagnosis and During Disease Course

Non-Clonal Serum Immunoglobulin Free Light Chains (FLC) as Markers of Overall Survival

The Ratio of Monoclonal to Polyclonal Immunoglobulins Assessed with the Hevylite Test Predicts Prognosis, Is Superior for Monitoring the Course of the Disease and Allows Detection of Monoclonal Immunoglobulin In Patients with Normal or Subnormal Involved Immunoglobulin Isotype

Quantification of Serum IgMκ and IgMλ In Patients with Waldenstrom's Macroglobulinemia (WM) at Diagnosis and During Disease Course; Clinical Correlations

Heavy/Light Chain Specific Immunoglobulin Ratios at Presentation Are Prognostic for Progression Free Survival in the IFM 2005-01 Myeloma Trial.

Isotype-Specific Heavy/Light Chain (HLC) Suppression as a Predictor of Myeloma Development in Monoclonal Gammopathy of Undetermined Significance (MGUS).

Serum FLC Levels at Presentation Have Independent Prognostic Significance in CLL and Levels Above 50mg/L Identify Patients with Progressive Disease.

A New Staging System for AL Amyloidosis Incorporating Serum Free Light Chains, cardiac Troponin-T and NT-ProBNP.

Abnormal Serum IgA Kappa / IgA Lambda Ratios at Maximum Response Predict Poor Progression Free Survival in Myeloma Patients.

Serum Free Light Chain and Serum Heavy / Light Chain Ratios Are Independently Prognostic in Multiple Myeloma Patients.

Association of High Levels of Free Light Chain and the Presence of Igh Translocations in Multiple Myeloma and Prognostic Implications.

AL amyloidosis associated with IgM paraproteinemia: clinical profile and treatment outcome

Combined Chemotherapy and High Cut-Off Hemodialysis Improve Outcomes in Multiple Myeloma Patients with Severe Renal Failure.

Prevalence of Light-Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS) among Olmsted County, Minnesota Residents Aged 50 Years or Greater.

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American Society of Hematology

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American Society of Hematology

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