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Philip N. Hawkins
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Journal Articles

Complete responses in AL amyloidosis are unequal: the impact of free light chain mass spectrometry in AL amyloidosis

Clinical Trials & Observations
Joshua Bomsztyk, Sriram Ravichandran, Hannah V. Giles, Nicola Wright, Oscar Berlanga, Jahanzaib Khwaja, Shameem Mahmood, Brendan Wisniowski, Oliver Cohen, Darren Foard, Janet Gilbertson, Muhammad U. Rauf, Neasa Starr, Ana Martinez-Naharro, Lucia Venneri, Carol Whelan, Marianna Fontana, Philip N. Hawkins, Julian D. Gillmore, Helen Lachmann, Stephen Harding, Guy Pratt, Ashutosh D. Wechalekar
Journal: Blood
Blood (2024) 143 (13): 1259–1268.
https://doi.org/10.1182/blood.2023022399
Published: 2024
Includes: Supplemental data
Journal Articles

Limited Utility of Mayo 2012 Cardiac Staging System for Risk Stratification of Patients with Advanced Cardiac AL Amyloidosis - Analysis of a Uniformly Treated Cohort of 1275 Patients

Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Charles Cohen, Darren Foard, Ana Martinez - Naharro, Lucia Venneri, Marianna Fontana, Philip N Hawkins, Julian Gillmore, Helen J Lachmann, Shameem Mahmood, Carol Whelan, Ashutosh D. Wechalekar
Journal: Blood
Blood (2023) 142 (Supplement 1): 537.
https://doi.org/10.1182/blood-2023-178243
Published: 2023
Journal Articles

Use of Matrix-Assisted Laser Desorption/Ionisation Time-of-Flight Mass Spectrometry (MALDI-TOF MS) Free Light Chain Assessment for the Diagnosis and Monitoring of Systemic Immunoglobulin Light Chain (AL) Amyloidosis

Joshua Bomsztyk, Sriram Ravichandran, Hannah Victoria Giles, Oscar Berlanga, Stephen Harding, Jahanzaib Khwaja, Shameem Mahmood, Brendan Wisniowski, Oliver C Cohen, Darren Foard, Janet Gilbertson, Ana Martinez De Azcona Naharro, Lucia Venneri, Carol Whelan, Marianna Fontana, Philip N Hawkins, Julian D Gillmore, Helen J Lachmann, Guy Pratt, Ashutosh D. Wechalekar
Journal: Blood
Blood (2022) 140 (Supplement 1): 2351–2353.
https://doi.org/10.1182/blood-2022-160018
Published: 2022
Journal Articles

Autologous Stem Cell Transplantation in AL-Amyloidosis Following Yttrium-90 Labelled Anti-CD66 Monoclonal Antibody As Sole Conditioning Is Associated with Low Toxicity and Demonstrable Disease Responses

Kim H. Orchard, Jon Langford, Paul Lloyd-Evans, Denise Phillips, Matthew Guy, Sofia Michopoulou, Gemma Lewis, Julian Williams, Clint Zvavamwe, Claire Hutchison, Jane Nunnick, Amanda Blackwell, Pei-San Chan, Caspar Wickham, Ann-Marie Quigley, Mark Cook, Graham Jackson, Philip N Hawkins, Ashutosh D. Wechalekar
Journal: Blood
Blood (2021) 138 (Supplement 1): 3819.
https://doi.org/10.1182/blood-2021-146300
Published: 2021
Journal Articles

The Prognostic Importance of the 6-Minute Walk Test in AL Amyloidosis

Oliver C Cohen, MBBS, BSc, FRCPath, Ananth Sathyanath, Sriram Ravichandran, MBBS, MRCP, FRCPath, Steven Law, MBBS, BSc, Richa Manwani, MBBS, FRCPath, BSc, Darren Foard, Sajitha Sachchithanantham, MBBS, BSc, FRCPath, Shameem Mahmood, Ana Martinez-Naharro, Marianna Fontana, Carol Whelan, Philip N Hawkins, Helen J Lachmann, Julian D Gillmore, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-137036
Published: 2020
Journal Articles

The Impact of Longitudinal Strain on Haematological and Cardiac Response and Survival in Patients with Systemic AL Amyloidosis

Oliver C Cohen, MBBS, BSc, FRCPath, Andreia Ismael, Richa Manwani, MBBS, FRCPath, BSc, Sriram Ravichandran, MBBS, MRCP, FRCPath, Steven Law, MBBS, BSc, Darren Foard, Ana Martinez-Naharro, Shameem Mahmood, Sajitha Sachchithananthan, Philip N Hawkins, Helen J Lachmann, Julian D Gillmore, Marianna Fontana, Rodney H Falk, MD, Carol Whelan, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-137391
Published: 2020
Journal Articles

A prospective observational study of 915 patients with systemic AL amyloidosis treated with upfront bortezomib

Clinical Trials & Observations
Richa Manwani, Oliver Cohen, Faye Sharpley, Shameem Mahmood, Sajitha Sachchithanantham, Darren Foard, Helen J. Lachmann, Cristina Quarta, Marianna Fontana, Julian D. Gillmore, Carol Whelan, Philip N. Hawkins, Ashutosh D. Wechalekar
Journal: Blood
Blood (2019) 134 (25): 2271–2280.
https://doi.org/10.1182/blood.2019000834
Published: 2019
Journal Articles

Quantitative Immunoprecipitation Free Light Chain Mass Spectrometry (QIP-FLC-MS) Simplifies Monoclonal Protein Assessment and Provides Added Clinical Value in Systemic AL Amyloidosis

Faye Amelia Sharpley, BA MA MSc MBBChir FRCPath, Hannah Victoria Giles, FRCPath, MRCP, Richa Manwani, MBBS, FRCPath, BSc, Shameem Mahmood, Sajitha Sachchithanantham, Helen J Lachmann, MA MB BChir MDFRCP, Julian D Gillmore, MBBS, MD PhD FRCP, Carol J Whelan, Philip N Hawkins, Ashutosh D Wechalekar, MB BS, MD FRCP, FRCPath, DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 4375.
https://doi.org/10.1182/blood-2019-128175
Published: 2019
Journal Articles

Treatment of IgM-associated immunoglobulin light-chain amyloidosis with rituximab-bendamustine

Clinical Trials & Observations
Richa Manwani, Sajitha Sachchithanantham, Shameem Mahmood, Darren Foard, Faye Sharpley, Tamer Rezk, Thirusha Lane, Cristina Quarta, Marianna Fontana, Helen J. Lachmann, Julian D. Gillmore, Carol Whelan, Philip N. Hawkins, Ashutosh D. Wechalekar
Journal: Blood
Blood (2018) 132 (7): 761–764.
https://doi.org/10.1182/blood-2018-04-846493
Published: 2018
Journal Articles

Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome

Dorota M. Rowczenio, Shelly Pathak, Juan I. Arostegui, Anna Mensa-Vilaro, Ebun Omoyinmi, Paul Brogan, Dan Lipsker, Thomas Scambler, Roger Owen, Hadija Trojer, Anna Baginska, Julian D. Gillmore, Ashutosh D. Wechalekar, Thirusha Lane, Rene Williams, Taryn Youngstein, Philip N. Hawkins, Sinisa Savic, Helen J. Lachmann
Journal: Blood
Blood (2018) 131 (9): 974–981.
https://doi.org/10.1182/blood-2017-10-810366
Published: 2018
Includes: Supplemental data
Journal Articles

Challenges of Using NT-Probnp for Response Assessment in Systemic AL Amyloidosis - Analysis of a Prospective Study

Ashutosh Wechalekar, MD FRCPath, Darren Foard, Carol Whelan, MD FRCP, Mariana Fontana, Thirusha Lane, RN MSc, Candida Quarta, Shameem Mahmood, FRCPath, Helen Lachmann, MD FRCP, Julian D Gillmore, MD PhD FRCP, Philip N Hawkins, MD PhD FMedSci
Journal: Blood
Blood (2016) 128 (22): 4511.
https://doi.org/10.1182/blood.V128.22.4511.4511
Published: 2016
Journal Articles

Natural history and outcome of light chain deposition disease

CME Clinical Trials & Observations
Rabya H. Sayed, Ashutosh D. Wechalekar, Janet A. Gilbertson, Paul Bass, Shameem Mahmood, Sajitha Sachchithanantham, Marianna Fontana, Ketna Patel, Carol J. Whelan, Helen J. Lachmann, Philip N. Hawkins, Julian D. Gillmore
Journal: Blood
Blood (2015) 126 (26): 2805–2810.
https://doi.org/10.1182/blood-2015-07-658872
Published: 2015
Includes: Supplemental data
Journal Articles

Oral Doxycycline Improves Outcomes of Stage III AL Amyloidosis - a Matched Case Control Study

Ashutosh Wechalekar, MD FRCPath, Carol Whelan, MDFRCP, Helen Lachmann, MDFRCP, Marianna Fontana, MD, Shameem Mahmood, FRCPath, Julian D Gillmore, MDPhDFRCP, Philip N Hawkins, MDPhDFMedSci
Journal: Blood
Blood (2015) 126 (23): 732.
https://doi.org/10.1182/blood.V126.23.732.732
Published: 2015
Journal Articles

Dose-Dependent Progressive Immunotherapeutic Clearance of Systemic Amyloid Deposits By Repeated Doses of Antibody to Serum Amyloid P Component (SAP)

Mark B Pepys, MDPhDFRS FMedSci, Louise M Cookson, BSc, Sharon V Barton, BSc MSc, Alienor C Berges, PharmD, Thirusha Lane, RN MSc, David Hutt, BAppSc, Marianna Fontana, MD, James C Moon, MD, Julian D Gillmore, MDPhDFRCP, Ashutosh Wechalekar, MDFRCPath FRCP, Philip N Hawkins, MDPhDFMedSci, Duncan B Richards, DM FRCP
Journal: Blood
Blood (2015) 126 (23): 1836.
https://doi.org/10.1182/blood.V126.23.1836.1836
Published: 2015
Journal Articles

A Prospective Study of Treatment Outcomes in 179 Patients with Advanced Cardiac Stage STAGE IIIb Amyloidosis

Belen Sevillano, Haematology Specialist, Ashutosh Wechalekar, MDFRCPath FRCP, Darren Foard, Specialist Nurse, Carol Whelan, MDFRCP, Marianna Fontana, MD, Cristina Quarta, Shameem Mahmood, FRCPath, Helen Lachmann, MDFRCP, Julian D Gillmore, MDPhDFRCP, Philip N Hawkins, MDPhDFMedSci
Journal: Blood
Blood (2015) 126 (23): 5357.
https://doi.org/10.1182/blood.V126.23.5357.5357
Published: 2015
Journal Articles

A Matched Case Control Study of Doxycycline Added to Chemotherapy for Reducing Early Mortality in Patients with Advanced Cardiac AL Amyloidosis from the Alchemy Study Cohort

Ashutosh Wechalekar, MD FRCPath, Carol Whelan, MD, Sajitha Sachchithanantham, MRCP, FRCPath, Marianna Fontana, MD, Shameem Mahmood, MRCP. FRCPath, Darren Foard, RN, Thirusha Lane, RN, Helen J Lachmann, MD FRCP, Julian D Gillmore, MD FRCP, Philip N Hawkins, MD FRCP, FMedSci
Journal: Blood
Blood (2014) 124 (21): 3485.
https://doi.org/10.1182/blood.V124.21.3485.3485
Published: 2014
Journal Articles

A European Collaborative Study of 230 Patients to Assess the Role of Cyclophosphamide, Bortezomib and Dexamethasone in Upfront Treatment of Patients with Systemic AL Amyloidosis

Giovanni Palladini, MD PhD, Sajitha Sachchithanantham, BSc,MBBS,MRCP,FRCPath,, Paolo Milani, MD, Julian D Gillmore, Andrea Foli, MD, Philip N Hawkins, Giampaolo Merlini, MD, Ashutosh D Wechalekar
Journal: Blood
Blood (2014) 124 (21): 305.
https://doi.org/10.1182/blood.V124.21.305.305
Published: 2014
Journal Articles

Exome Sequencing to Define a Genetic Signature of Plasma Cells in Systemic AL Amyloidosis

Eileen M Boyle, MD, Brian A Walker, PhD, Dorota Rowczienio, MSc, Christopher P Wardell, PhD, Alexander Murison, PhD, Aneta Mikulasova, M.Sc., Sajitha Sachchithanantham, BSc,MBBS,MRCP,FRCPath,, Anna Baginska, Shameem Mahmood, MRCP. FRCPath, Julian D Gillmore, Helen J Lachmann, MD FRCP, Philip N Hawkins, MD FRCP, FMedSci, Xavier Leleu, MD PhD, Faith E Davies, MD, Gareth J. Morgan, MD PhD, Ashutosh Wechalekar, MDFRCPath
Journal: Blood
Blood (2014) 124 (21): 726.
https://doi.org/10.1182/blood.V124.21.726.726
Published: 2014
Journal Articles

Longterm Outcomes and Improved Renal Function with Autologous Stem Cell Transplantation (ASCT) in Light Chain Deposition Disease (LCDD)

Kate Stringaris, MBBS, MRCP, FRCPath, PhD, Rabya Sayed, MRCP, Helen J Lachmann, MD FRCP, Julian D Gillmore, Philip N Hawkins, Ashutosh Wechelaker, MDMRCP FRCPath
Journal: Blood
Blood (2014) 124 (21): 1198.
https://doi.org/10.1182/blood.V124.21.1198.1198
Published: 2014
Journal Articles

The Prognostic Significance of Phenotypically ‘Normal’ Plasma Cells in Chemotherapy Treated AL Patients with Underlying MGUS and Multiple Myeloma

Sajitha Sachchithanantham, BSc,MBBS,MRCP,FRCPath,, Ruth M de Tute, Anna Baginska, Christopher Parrish, MD, Shameem Mahmood, MRCP. FRCPath, Andy Rawstron, PhD, Julian D Gillmore, MD FRCP, Helen J Lachmann, MD FRCP, Philip N Hawkins, Roger G Owen, MD, Ashutosh Wechalekar, Dr
Journal: Blood
Blood (2014) 124 (21): 2073.
https://doi.org/10.1182/blood.V124.21.2073.2073
Published: 2014