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Journal Articles

Complete responses in AL amyloidosis are unequal: the impact of free light chain mass spectrometry in AL amyloidosis

Clinical Trials & Observations
Joshua Bomsztyk, Sriram Ravichandran, Hannah V. Giles, Nicola Wright, Oscar Berlanga, Jahanzaib Khwaja, Shameem Mahmood, Brendan Wisniowski, Oliver Cohen, Darren Foard, Janet Gilbertson, Muhammad U. Rauf, Neasa Starr, Ana Martinez-Naharro, Lucia Venneri, Carol Whelan, Marianna Fontana, Philip N. Hawkins, Julian D. Gillmore, Helen Lachmann, Stephen Harding, Guy Pratt, Ashutosh D. Wechalekar
Journal: Blood
Blood (2024) 143 (13): 1259–1268.
https://doi.org/10.1182/blood.2023022399
Published: 2024
Includes: Supplemental data
Journal Articles

Limited Utility of Mayo 2012 Cardiac Staging System for Risk Stratification of Patients with Advanced Cardiac AL Amyloidosis - Analysis of a Uniformly Treated Cohort of 1275 Patients

Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Charles Cohen, Darren Foard, Ana Martinez - Naharro, Lucia Venneri, Marianna Fontana, Philip N Hawkins, Julian Gillmore, Helen J Lachmann, Shameem Mahmood, Carol Whelan, Ashutosh D. Wechalekar
Journal: Blood
Blood (2023) 142 (Supplement 1): 537.
https://doi.org/10.1182/blood-2023-178243
Published: 2023
Journal Articles

Use of Matrix-Assisted Laser Desorption/Ionisation Time-of-Flight Mass Spectrometry (MALDI-TOF MS) Free Light Chain Assessment for the Diagnosis and Monitoring of Systemic Immunoglobulin Light Chain (AL) Amyloidosis

Joshua Bomsztyk, Sriram Ravichandran, Hannah Victoria Giles, Oscar Berlanga, Stephen Harding, Jahanzaib Khwaja, Shameem Mahmood, Brendan Wisniowski, Oliver C Cohen, Darren Foard, Janet Gilbertson, Ana Martinez De Azcona Naharro, Lucia Venneri, Carol Whelan, Marianna Fontana, Philip N Hawkins, Julian D Gillmore, Helen J Lachmann, Guy Pratt, Ashutosh D. Wechalekar
Journal: Blood
Blood (2022) 140 (Supplement 1): 2351–2353.
https://doi.org/10.1182/blood-2022-160018
Published: 2022
Journal Articles

Graded Renal Response Criteria for Light Chain (AL) Amyloidosis

Eli Muchtar, Brendan Wisniowski, Giovanni Palladini, Paolo Milani, Giampaolo Merlini, Stefan Schönland, Kaya Veelken, Ute Hegenbart, Angela Dispenzieri, Shaji Kumar, Nelson Leung, Efstathios Kastritis, Meletios A. Dimopoulos, Michaela Liedtke, Ronald Witteles, Vaishali Sanchorawala, Raphael Szalat, Heather J Landau, Erica Petrlik, Suzanne Lentzsch, Alexander Coltoff, Joan Bladé, M. Teresa Cibeira, Oliver C Cohen, Darren Foard, Julian D Gillmore, Helen J Lachmann, Ashutosh D. Wechalekar, Morie A. Gertz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2721.
https://doi.org/10.1182/blood-2021-149594
Published: 2021
Journal Articles

Graded Cardiac Response Criteria for AL Amyloidosis: The Impact of Depth of Cardiac Response on Survival

Eli Muchtar, Angela Dispenzieri, Brendan Wisniowski, Giovanni Palladini, Paolo Milani, Giampaolo Merlini, Stefan Schönland, Kaya Veelken, Ute Hegenbart, Shaji Kumar, Efstathios Kastritis, Meletios A. Dimopoulos, Michaela Liedtke, Ronald Witteles, Vaishali Sanchorawala, Raphael Szalat, Heather J Landau, Erica Petrlik, Suzanne Lentzsch, Alexander Coltoff, Joan Bladé, M. Teresa Cibeira, Oliver Cohen, Darren Foard, Ashutosh D. Wechalekar, Morie A. Gertz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2720.
https://doi.org/10.1182/blood-2021-149222
Published: 2021
Journal Articles

The Prognostic Importance of the 6-Minute Walk Test in AL Amyloidosis

Oliver C Cohen, MBBS, BSc, FRCPath, Ananth Sathyanath, Sriram Ravichandran, MBBS, MRCP, FRCPath, Steven Law, MBBS, BSc, Richa Manwani, MBBS, FRCPath, BSc, Darren Foard, Sajitha Sachchithanantham, MBBS, BSc, FRCPath, Shameem Mahmood, Ana Martinez-Naharro, Marianna Fontana, Carol Whelan, Philip N Hawkins, Helen J Lachmann, Julian D Gillmore, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-137036
Published: 2020
Journal Articles

The Impact of Longitudinal Strain on Haematological and Cardiac Response and Survival in Patients with Systemic AL Amyloidosis

Oliver C Cohen, MBBS, BSc, FRCPath, Andreia Ismael, Richa Manwani, MBBS, FRCPath, BSc, Sriram Ravichandran, MBBS, MRCP, FRCPath, Steven Law, MBBS, BSc, Darren Foard, Ana Martinez-Naharro, Shameem Mahmood, Sajitha Sachchithananthan, Philip N Hawkins, Helen J Lachmann, Julian D Gillmore, Marianna Fontana, Rodney H Falk, MD, Carol Whelan, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-137391
Published: 2020
Journal Articles

A prospective observational study of 915 patients with systemic AL amyloidosis treated with upfront bortezomib

Clinical Trials & Observations
Richa Manwani, Oliver Cohen, Faye Sharpley, Shameem Mahmood, Sajitha Sachchithanantham, Darren Foard, Helen J. Lachmann, Cristina Quarta, Marianna Fontana, Julian D. Gillmore, Carol Whelan, Philip N. Hawkins, Ashutosh D. Wechalekar
Journal: Blood
Blood (2019) 134 (25): 2271–2280.
https://doi.org/10.1182/blood.2019000834
Published: 2019
Journal Articles

Treatment of IgM-associated immunoglobulin light-chain amyloidosis with rituximab-bendamustine

Clinical Trials & Observations
Richa Manwani, Sajitha Sachchithanantham, Shameem Mahmood, Darren Foard, Faye Sharpley, Tamer Rezk, Thirusha Lane, Cristina Quarta, Marianna Fontana, Helen J. Lachmann, Julian D. Gillmore, Carol Whelan, Philip N. Hawkins, Ashutosh D. Wechalekar
Journal: Blood
Blood (2018) 132 (7): 761–764.
https://doi.org/10.1182/blood-2018-04-846493
Published: 2018
Journal Articles

Safety and Efficacy of Deferred Autologous Stem Cell Transplantation in Patients with Systemic AL Amyloidosis with Significant Cardiac Involvement at Presentation

Richa Manwani, MBBS, FRCPath, BSc, Ute Hegenbart, Darren Foard, Shameem Mahmood, Sajitha Sachchithanantham, BSc,FRCPath,MBBS,MRCP, Kwee Yong, PhD, Rakesh Popat, MD PhD, Charalampia Kyriakou, MD PhD, Neil Rabin, Marianna Fontana, Carol Whelan, Helen Lachmann, Thirusha Lane, Candida Quarta, Julian Gillmore, Tobias Dittrich, MD, Christoph Kimmich, MD, Philip Hawkins, Stefan Schönland, MD, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2017) 130 (Supplement 1): 1815.
https://doi.org/10.1182/blood.V130.Suppl_1.1815.1815
Published: 2017
Journal Articles

Prolonged Progression Free Survival and Time to Next Treatment Are Achievable Outcomes in Patients with Systemic AL Amyloidosis Treated with Novel Agent Chemotherapy: Analysis of the Alchemy Study

Richa Manwani, MBBS, FRCPath, BSc, Darren Foard, Shameem Mahmood, Sajitha Sachchithanantham, BSc,FRCPath,MBBS,MRCP, Marianna Fontana, Carol Whelan, Candida Quarta, Thirusha Lane, Helen Lachmann, Julian Gillmore, Philip Hawkins, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2017) 130 (Supplement 1): 1816.
https://doi.org/10.1182/blood.V130.Suppl_1.1816.1816
Published: 2017
Journal Articles

Challenges of Using NT-Probnp for Response Assessment in Systemic AL Amyloidosis - Analysis of a Prospective Study

Ashutosh Wechalekar, MD FRCPath, Darren Foard, Carol Whelan, MD FRCP, Mariana Fontana, Thirusha Lane, RN MSc, Candida Quarta, Shameem Mahmood, FRCPath, Helen Lachmann, MD FRCP, Julian D Gillmore, MD PhD FRCP, Philip N Hawkins, MD PhD FMedSci
Journal: Blood
Blood (2016) 128 (22): 4511.
https://doi.org/10.1182/blood.V128.22.4511.4511
Published: 2016
Journal Articles

A Prospective Study of Treatment Outcomes in 179 Patients with Advanced Cardiac Stage STAGE IIIb Amyloidosis

Belen Sevillano, Haematology Specialist, Ashutosh Wechalekar, MDFRCPath FRCP, Darren Foard, Specialist Nurse, Carol Whelan, MDFRCP, Marianna Fontana, MD, Cristina Quarta, Shameem Mahmood, FRCPath, Helen Lachmann, MDFRCP, Julian D Gillmore, MDPhDFRCP, Philip N Hawkins, MDPhDFMedSci
Journal: Blood
Blood (2015) 126 (23): 5357.
https://doi.org/10.1182/blood.V126.23.5357.5357
Published: 2015
Journal Articles

A Matched Case Control Study of Doxycycline Added to Chemotherapy for Reducing Early Mortality in Patients with Advanced Cardiac AL Amyloidosis from the Alchemy Study Cohort

Ashutosh Wechalekar, MD FRCPath, Carol Whelan, MD, Sajitha Sachchithanantham, MRCP, FRCPath, Marianna Fontana, MD, Shameem Mahmood, MRCP. FRCPath, Darren Foard, RN, Thirusha Lane, RN, Helen J Lachmann, MD FRCP, Julian D Gillmore, MD FRCP, Philip N Hawkins, MD FRCP, FMedSci
Journal: Blood
Blood (2014) 124 (21): 3485.
https://doi.org/10.1182/blood.V124.21.3485.3485
Published: 2014
Journal Articles

Biweekly Bortezomib Is More Efficacious Than Weekly Bortezomib When Used As First Line In Patients With Systemic AL Amyloidosis

Sajitha Sachchithanantham, MRCP, FRCPath, Shameem Mahmood, MRCP. FRCPath, Rabya Sayed, MRCP, Ketna Patel, MRCP, Marianna Fontana, MD, Thirusha Lane, RN, Lisa Rannigan, RN, Darren Foard, RN, Carol Whelan, MD, Helen Lachmann, MD, Julian D Gillmore, MD, Philip N Hawkins, MD, Ashutosh Wechalekar, MD, FRCPath
Journal: Blood
Blood (2013) 122 (21): 1981.
https://doi.org/10.1182/blood.V122.21.1981.1981
Published: 2013
Journal Articles

Use Of Plasma Cell Immunophenotype As Prognostic Markers In Patients With Systemic AL Amyloidosis

Sajitha Sachchithanantham, MRCP, FRCPath, Anna Baginska, Dorota Rowczenio, Shameem Mahmood, MRCP, FRCPath, Rabya Sayed, MRCP, Ketna Patel, MRCP, Thirusha Lane, RN, Lisa Rannigan, RN, Darren Foard, RN, Carol Whelan, MD, Helen Lachmann, MD, Julian D Gillmore, MD, Philip N Hawkins, MD, Ashutosh Wechalekar, MD FRCPath
Journal: Blood
Blood (2013) 122 (21): 3120.
https://doi.org/10.1182/blood.V122.21.3120.3120
Published: 2013
Journal Articles

Risk Of Progression Of Localised Amyloidosis To Systemic Disease In 606 Patients Over 30 Years

Shameem Mahmood, MRCP. FRCPath, Sajitha Sachchithanantham, MRCP. FRCPath, Frank Bridoux, Thirusha Lane, RN, Lisa Rannigan, RN, Darren Foard, RN, Rabya Sayed, MRCP, Ketna Patel, MRCP, Marianna Fontanna, MD, Carol Whelan, MD, Helen J Lachmann, MD, FRCP, Julian D Gillmore, MD, Philip N Hawkins, MD, Ashutosh Wechalekar, MD FRCPath
Journal: Blood
Blood (2013) 122 (21): 3143.
https://doi.org/10.1182/blood.V122.21.3143.3143
Published: 2013
Journal Articles

A European collaborative study of treatment outcomes in 346 patients with cardiac stage III AL amyloidosis

Ashutosh D. Wechalekar, Stefan O. Schonland, Efstathios Kastritis, Julian D. Gillmore, Meletios A. Dimopoulos, Thirusha Lane, Andrea Foli, Darren Foard, Paolo Milani, Lisa Rannigan, Ute Hegenbart, Philip N. Hawkins, Giampaolo Merlini, Giovanni Palladini
Journal: Blood
Blood (2013) 121 (17): 3420–3427.
https://doi.org/10.1182/blood-2012-12-473066
Published: 2013
Journal Articles

A Matched Comparison of Cyclophosphamide, Bortezomib and Dexamethasone (CVD) Versus Cyclophosphamide, Thalidomide and Dexamethasone (CTD) in the Treatment of Mayo Cardiac Stage III Patients with AL Amyloidosis.

Christopher P Venner, MD, Thirusha Lane, RN, Darren Foard, RN, Lisa Rannigan, RN, Shameem Mahmood, MBBCh. FRCPath, Simon DJ Gibbs, Jennifer Pinney, MD, Sanjay Banypersad, MD, Jason Dungu, Carol Whelan, Helen Lachmann, MD, Julian D Gillmore, MD, Philip N Hawkins, MD, Ashutosh Wechalekar, MD
Journal: Blood
Blood (2012) 120 (21): 2966.
https://doi.org/10.1182/blood.V120.21.2966.2966
Published: 2012
Journal Articles

Continuous Therapy with Lenalidomide Correlates with Improved Progression Free Survival in Heavily Pre-Treated Patients with AL Amyloidosis.

Shameem Mahmood, MBBCh. FRCPath, Christopher P. Venner, MD, Thirusha Lane, RN, Lisa Rannigan, RN, Darren Foard, RN, Jennifer Pinney, MD, Sanjay Banypersad, MD, Jason Dungu, Carol Whelan, Helen J Lachmann, MD, FRCP, Julian D Gillmore, MD, Philip N Hawkins, MD, Ashutosh Wechalekar, MD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 2978.
https://doi.org/10.1182/blood.V120.21.2978.2978
Published: 2012