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Journal Articles

Prospective Evaluation of ABL Kinase Domain Mutational Analysis By Next-Generation-Sequencing in Newly Diagnosed CP CML Patients Undergoing First-Line Treatment with Nilotinib Alone or Nilotinib + Pegylated Interferon-α2a in a Prospective Phase III Trial

Hugues de Lavallade, MD PhD, Sophie Jackson, BSc, Aytug Kizilors, PhD, Gabriel Etienne, MD PhD, Francoise Huguet, MD, Agnes Guerci-Bresler, MD PhD, Delphine Rea, MD, Claudine Chollet, MSc, Stephane Morisset, BioStat, Fanny Robbesyn, BSc, Francois-Xavier Mahon, MD PhD, Stephanie Dulucq, PharmD, PhD, Franck E Nicolini, MD PhD

Blood (2019) 134 (Supplement_1): 664.

https://doi.org/10.1182/blood-2019-125108

Published: 2019

Journal Articles

Interim Analysis of a Prospective Multicentre Study Using Next Generation Sequencing for Kinase Domain Mutational Analysis in CML Patients on First or Subsequent TKI Therapy

Blood (2019) 134 (Supplement_1): 2935.

https://doi.org/10.1182/blood-2019-129825

Published: 2019

Journal Articles

Telomeric Length to Characterize and Prognosticate Bone Marrow Failure, Risk of Clonal Evolution and Multi-System Complications in Aplastic Anemia and Other Hypocellular Cytopenic Disorders, Independent of Telomere Gene Complex Mutations

Shreyans Gandhi, MBBS,MDDNB,MRCP,FRCPath,MPhil, Jie Jiang, PhD, Simon Slade, BSc, Austin Kulasekararaj, MD MRCP, FRCPath, Victoria Potter, BSc, MBBS, FRCPA, Varun Mehra, MBBS,MRCP,FRCPath, Petra Muus, MD PhD, Andrea Da Silva, MBBS, Sudarshan Gurung, MBBS, MRCP, Alice Mason, B.Pharm, Aytug Kizilors, PhD, Nicholas Lea, PhD, Sahar Mansour, MD, Robin M. Ireland, MBBS, FRCP, FRCPath, Ghulam J. Mufti, MBBS, FRCP, FRCPath, DM, Judith Marsh, MD FRCPath

Blood (2019) 134 (Supplement_1): 3749.

https://doi.org/10.1182/blood-2019-130754

Published: 2019

Journal Articles

Clinical Intervention Using NGS-Based Kinase Domain Mutation Testing in CML Patients

Aytug Kizilors, PhD, Patrick Harrington, FRCPath, MRCP, Sophie Jackson, BSc, Nicholas Lea, PhD, Joel Newman, MBBS, MRCP, BSc, FRCPath, Richard Gale, FRCPath, FRCP, Sandra Hassan, MD, Evangelia Dimitriadou, MD, Elena Crisà, MD, Luke Ficinski, BSc, Isabel Sa, BSc, Anita Arasaretnam, MD, Vijayavalli Dhanapal, MD, Timothy Corbett, FRCP, FRCPath, Robin M. Ireland, FRCP, Antonio Pagliuca, Ghulam J. Mufti, Hugues De Lavallade

Blood (2018) 132 (Supplement 1): 3025.

https://doi.org/10.1182/blood-2018-99-118905

Published: 2018

Journal Articles

Low-Dose Second Generation TKI Is an Effective Approach to Reduce TKI Related Side Effects and Toxicity While Preserving Molecular Response in CML Patients with TKI Intolerance

Varun Mehra, MRCP, FRCPath, Titilola Oyebamiji, Stefanie Widya, Robin M. Ireland, FRCP, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Kavita Raj, MD PhD, Donal McLornan, Judith Marsh, MD, Victoria Potter, Joanna Large, Isabel Duggins, Aytug Kizilors, PhD, Nicholas Lea, PhD, Antonio Pagliuca, MD, Ghulam Mufti, DM, FRCP, FRCPath, Hugues De Lavallade

Blood (2017) 130 (Supplement 1): 5250.

https://doi.org/10.1182/blood.V130.Suppl_1.5250.5250

Published: 2017

Journal Articles

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Steven Best, PhD, Aytug Kizilors, PhD, Shreyans Gandhi, MD DNB, MRCP, FRCPath, Victoria T Potter, Judith C. W. Marsh, MD FRCP, FRCPath, Nicholas Lea, PhD, Robin M. Ireland, FRCP, FRCPath, Ghulam J Mufti, MD

Blood (2016) 128 (22): 1981.

https://doi.org/10.1182/blood.V128.22.1981.1981

Published: 2016

Journal Articles

Impact of Finding of Low Level Kinase Domain Mutations Using Ultra Deep Next Generation Sequencing in Patients with Chronic Phase CML

Aytug Kizilors, PhD, Elena Crisa, MD, Nicholas Lea, PhD, Steven Best, PhD, Mian Syed, PhD, Robin M. Ireland, FRCP, FRCPath, Maadh Aldouri, FRCPath, Christopher Pocock, Timothy Corbett, FRCP, FRCPath, Emily Elizabeth Bart-Smith, MRCP,BSc, Richard Gale, FRCPath, FRCP, Clare Wykes, FRCPath, FRCP, Simon Weston-Smith, FRCP, FRCPath, Donal McLornan, MDPhD, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J. Mufti, MD PhD, Hugues de Lavallade, MD PhD

Blood (2015) 126 (23): 347.

https://doi.org/10.1182/blood.V126.23.347.347

Published: 2015

Journal Articles

Autologous Ex-Vivo Regulatory T Cells(Tregs) Expansion in Aplastic Anemia for Potential Clinical Use

Benedetta Costantini, MD, Shahram Kordasti, MD PhD, Seidl Thomas, Smith Alexander, PhD, Mian Syed, PhD, Aytug Kizilors, PhD, Martinez-Llordella Marc, PhD, Judith C Marsh, MD, Ghulam J. Mufti, MD PhD

Blood (2015) 126 (23): 3617.

https://doi.org/10.1182/blood.V126.23.3617.3617

Published: 2015

Journal Articles

NLRP3 Inflammosome Polymorphisms Are Enriched in Myelodysplastic Syndrome Patients with Autoimmune Disorders

Syed A Mian, BSc, M.Phil, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Aytug Kizilors, PhD, Kathy L McGraw, PhD, Shahram Kordasti, MD PhD, Stephan Menzel, PhD, Alexander e Smith, PhD, Pilar Perezabellan, BSc, David Sallman, MD, Alan F. List, MD, Ghulam J Mufti, FRCP, FRCPath

Blood (2015) 126 (23): 1659.

https://doi.org/10.1182/blood.V126.23.1659.1659

Published: 2015

Journal Articles

Kings Health Partners 17 Gene Amplicon Panel for Next Generation Sequencing One Stop Mutational Assessment In Myeloid Malignancies

Nicholas C Lea, PhD, Atiyeh Abdallah, PhD, Aytug Kizilors, PhD, Alexander E Smith, PhD, Syed A Mian, Azim M Mohamedali, PhD, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2011) 118 (21): 748.

https://doi.org/10.1182/blood.V118.21.748.748

Published: 2011

Journal Articles

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

Blood (2010) 116 (21): 125.

https://doi.org/10.1182/blood.V116.21.125.125

Published: 2010

Journal Articles

RFUSIN2 - a Clinical Grade Lentiviral Vector Co-Expressing CD80/IL-2 Manufactured Under GMP for a Phase I Clinical Trial Study of Immune Gene Therapy for Poor Prognosis Acute Myeloid Leukaemia

Lucas Chan, Wendy Ingram, Nicola Hardwick, David Darling, Joti Bhalla, Aytug Kizilors, Shahram Y Kordasti, Ghulam J Mufti, Farzin Farzaneh

Blood (2008) 112 (11): 4630.

https://doi.org/10.1182/blood.V112.11.4630.4630

Published: 2008

NARROW

Prospective Evaluation of ABL Kinase Domain Mutational Analysis By Next-Generation-Sequencing in Newly Diagnosed CP CML Patients Undergoing First-Line Treatment with Nilotinib Alone or Nilotinib + Pegylated Interferon-α2a in a Prospective Phase III Trial

Interim Analysis of a Prospective Multicentre Study Using Next Generation Sequencing for Kinase Domain Mutational Analysis in CML Patients on First or Subsequent TKI Therapy

Telomeric Length to Characterize and Prognosticate Bone Marrow Failure, Risk of Clonal Evolution and Multi-System Complications in Aplastic Anemia and Other Hypocellular Cytopenic Disorders, Independent of Telomere Gene Complex Mutations

Clinical Intervention Using NGS-Based Kinase Domain Mutation Testing in CML Patients

Low-Dose Second Generation TKI Is an Effective Approach to Reduce TKI Related Side Effects and Toxicity While Preserving Molecular Response in CML Patients with TKI Intolerance

Targeted Sequencing of 647 Patients with Myeloid Malignancies, Marrow Failures and Cytopenia: A Prospective Analysis

Impact of Finding of Low Level Kinase Domain Mutations Using Ultra Deep Next Generation Sequencing in Patients with Chronic Phase CML

Autologous Ex-Vivo Regulatory T Cells(Tregs) Expansion in Aplastic Anemia for Potential Clinical Use

NLRP3 Inflammosome Polymorphisms Are Enriched in Myelodysplastic Syndrome Patients with Autoimmune Disorders

Kings Health Partners 17 Gene Amplicon Panel for Next Generation Sequencing One Stop Mutational Assessment In Myeloid Malignancies

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

RFUSIN2 - a Clinical Grade Lentiviral Vector Co-Expressing CD80/IL-2 Manufactured Under GMP for a Phase I Clinical Trial Study of Immune Gene Therapy for Poor Prognosis Acute Myeloid Leukaemia

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American Society of Hematology

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American Society of Hematology

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