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Journal Articles

MELK mediates the stability of EZH2 through site-specific phosphorylation in extranodal natural killer/T-cell lymphoma

Boheng Li, Junli Yan, The Phyu, Shuangyi Fan, Tae-Hoon Chung, Nurulhuda Mustafa, Baohong Lin, Lingzhi Wang, Pieter Johan Adam Eichhorn, Boon-Cher Goh, Siok-Bian Ng, Dennis Kappei, Wee-Joo Chng
Journal: Blood
Blood (2019) 134 (23): 2046–2058.
https://doi.org/10.1182/blood.2019000381
Published: 2019
Includes: Supplemental data
Journal Articles

ASLAN003, a Novel and Potent Dihydroorotate Dehydrogenase (DHODH) Inhibitor, Induces Differentiation of Acute Myeloid Leukemia

Jianbiao Zhou, MD,PhD, Jessie Yiying Quah, B.S., Jing Yuan Chooi, BSc, Sabrina Hui-Min Toh, B.S., Yvonne Ng, B.S., Baohong Lin, B.S., Motomi Osato, MD, PhD, Qihui Seet, B.S., PhD, A.G. Lisa Ooi, B.S., PhD, Bertil Lindmark, MD PhD, Mark McHale, B.S., PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4047.
https://doi.org/10.1182/blood-2018-99-114392
Published: 2018
Journal Articles

Plasma HCK Level As a Biomarker Predicting Poor Outcome in Acute Myeloid Leukemia

Pak Ling Lui, MBBS, Elaine Seah, BSc, Jianbiao Zhou, MD PhD, Baohong Lin, BSc, Wee Joo Chng, MB ChB, MRCP, PhD, Chin Hin Ng, MD MRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 3862.
https://doi.org/10.1182/blood.V130.Suppl_1.3862.3862
Published: 2017
Journal Articles

Plasma LRG1 Protein Are Overexpressed in Acute Myeloid Leukemia with High Sensitivity and High Specificity in Differentiating Leukemic Plasma from Normal Plasma — a Potential Biomarker for Minimal Residual Disease Detection

Chin Hin Ng, MD MRCP, Xu Liang, PhD, Jianbiao Zhou, MD PhD, Elaine Seah, BSc, Baohong Lin, BSc, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP, Yoon-Pin Lim, BSc, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5083.
https://doi.org/10.1182/blood.V130.Suppl_1.5083.5083
Published: 2017
Journal Articles

EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma

Junli Yan, Boheng Li, Baohong Lin, Pei Tsung Lee, Tae-Hoon Chung, Joy Tan, Chonglei Bi, Xue Ting Lee, Viknesvaran Selvarajan, Siok-Bian Ng, Henry Yang, Qiang Yu, Wee-Joo Chng
Journal: Blood
Blood (2016) 128 (7): 948–958.
https://doi.org/10.1182/blood-2016-01-690701
Published: 2016
Includes: Supplemental data
Journal Articles

EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity

Junli Yan, Siok-Bian Ng, Jim Liang-Seah Tay, Baohong Lin, Tze Loong Koh, Joy Tan, Viknesvaran Selvarajan, Shaw-Cheng Liu, Chonglei Bi, Shi Wang, Shoa-Nian Choo, Norio Shimizu, Gaofeng Huang, Qiang Yu, Wee-Joo Chng
Journal: Blood
Blood (2013) 121 (22): 4512–4520.
https://doi.org/10.1182/blood-2012-08-450494
Published: 2013
Includes: Supplemental data
Journal Articles

EZH2 Is Aberrantly Expressed and Plays a Pro-Proliferative Role Independent of Its Methyltransferase Activity in Natural Killer/T-Cell Lymphoma

Wee-Joo Chng, Assoc/Prof, Junli Yan, PhD, Siok-Bian NG, Jim Tay, Ph.D., Baohong Lin, BSc, Tze-Loong Koh, B.sc., Joy Tan, BSc, Viknesvaran Selvarajan, Shaw-Cheng Liu, B.sc., Chonglei Bi, B.sc., Gaofeng Huang, PhD, Qiang Yu, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3498.
https://doi.org/10.1182/blood.V120.21.3498.3498
Published: 2012
Journal Articles

Dysregulated MicroRNA Affects Pathways and Targets of Biological Relevance in Nasal-Type Natural Killer/T-Cell Lymphoma

Wee-Joo Chng, M.B.Ch.B, Junli Yan, PhD, Gaofeng Huang, PhD, Viknesvaran Selvarajan, BSc, Jim Tay, BSc, Baohong Lin, BSc, Chonglei Bi, B.sc., Joy Tan, BSc, Siok-Bian Ng, MB ChB
Journal: Blood
Blood (2011) 118 (21): 2637.
https://doi.org/10.1182/blood.V118.21.2637.2637
Published: 2011
Journal Articles

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma

Siok-Bian Ng, Junli Yan, Gaofeng Huang, Viknesvaran Selvarajan, Jim Liang-Seah Tay, Baohong Lin, Chonglei Bi, Joy Tan, Yok-Lam Kwong, Norio Shimizu, Katsuyuki Aozasa, Wee-Joo Chng
Journal: Blood
Blood (2011) 118 (18): 4919–4929.
https://doi.org/10.1182/blood-2011-07-364224
Published: 2011
Includes: Supplemental data