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Journal Articles

Phase II Study of a JAK1/2 Inhibitor Ruxolitinib for Systemic Chronic Active Epstein-Barr Virus Disease: An Investigator-Initiated Trial

Yu Uemura, Masahide Yamamoto, Masataka Ishimura, Hirokazu Kanegane, Akihisa Sawada, Akihiro Hirakawa, Ken-Ichi Imadome, Mayumi Yoshimori, Masashi Nagata, Norio Shimizu, Ryuji Koike, Ayako Arai

Blood (2022) 140 (Supplement 1): 6571–6572.

https://doi.org/10.1182/blood-2022-168565

Published: 2022

Journal Articles

Expression Profile of EBV-Derived Micro-RNA in Systemic Chronic Active EBV Disease

Mayumi Yoshimori, Ayaka Ohashi, Kotaro Yoshioka, Takanori Yokota, Norio Shimizu, Miwako Nishio, Ayako Arai

Blood (2022) 140 (Supplement 1): 9247–9248.

https://doi.org/10.1182/blood-2022-169693

Published: 2022

Journal Articles

The Presence of Defective Epstein-Barr Virus (EBV) Infection in Patients with EBV-Associated Hematological Malignancy

Yusuke Okuno, MDPhD, Takayuki Murata, MD, PhD, Yoshitaka Sato, MD, PhD, Hideki Muramatsu, MD PhD, Yoshinori Ito, MD PhD, Takahiro Watanabe, D.MD, PhD, Tatsuya Okuno, MD, Norihiro Murakami, MD, Kenichi Yoshida, MD PhD, Akihisa Sawada, MD PhD, Masami Inoue, MD, Keisei Kawa, MD, PhD, Masao Seto, MD PhD, Koichi Ohshima, MDPhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Satoru Miyano, PhD, Yohei Narita, PhD, Masahiro Yoshida, MD PhD, Fumi Goshima, PhD, Junichi Kawada, MD PhD, Tetsuya Nishida, MD PhD, Hitoshi Kiyoi, MD PhD, Seiichi Kato, MD, PhD, Shigeo Nakamura, MD PhD, Satoko Morishima, MD PhD, Shigeyoshi Fujiwara, MD, PhD, Norio Shimizu, PhD, Yasushi Isobe, MD, PhD, Masaaki Noguchi, MD, PhD, Atsushi Kikuta, MD, Keiji Iwatsuki, MD, PhD, Yoshiyuki Takahashi, MD, PhD, Seiji Kojima, MD PhD, Seishi Ogawa, MD PhD, Hiroshi Kimura, MD, Ph. D.

Blood (2018) 132 (Supplement 1): 1562.

https://doi.org/10.1182/blood-2018-99-113801

Published: 2018

Journal Articles

Histone Deacetylase Inhibitors Downregulate CCR4 Expression and Decrease Mogamulizumab Efficacy in CCR4-Positive Mature T-Cell Lymphomas

Akihiro Kitadate, MD, Sho Ikeda, MD, Fumito Abe, MD PhD, Naoto Takahashi, MD PhD, Norio Shimizu, PhD, Kosei Matsue, MD PhD, Hiroyuki Tagawa, MD PhD

Blood (2017) 130 (Supplement 1): 720.

https://doi.org/10.1182/blood.V130.Suppl_1.720.720

Published: 2017

Journal Articles

Receptor-type tyrosine-protein phosphatase κ directly targets STAT3 activation for tumor suppression in nasal NK/T-cell lymphoma

Yun-Wen Chen, Tianhuan Guo, Lijun Shen, Kai-Yau Wong, Qian Tao, William W. L. Choi, Rex K. H. Au-Yeung, Yuen-Piu Chan, Michelle L. Y. Wong, Johnny C. O. Tang, Wei-Ping Liu, Gan-Di Li, Norio Shimizu, Florence Loong, Eric Tse, Yok-Lam Kwong, Gopesh Srivastava

Blood (2015) 125 (10): 1589–1600.

https://doi.org/10.1182/blood-2014-07-588970

Published: 2015

Includes: Supplemental data

Journal Articles

Multiplex PCR for Virus Infections after Allogeneic Hematopoietic Stem Cell Transplantation

Natsuko Inazawa, MD, Tsukasa Hori, MD PhD, Masaki Yamamoto, MD PhD, Keita Igarashi, MD, Hiroyuki Tsutsumi, PhD, Masanori Nojima, MD PhD, Nobuhiro Suzuki, MD PhD, Norio Shimizu, MD PhD, Naoki Hatakeyama, MD PhD

Blood (2014) 124 (21): 5845.

https://doi.org/10.1182/blood.V124.21.5845.5845

Published: 2014

Journal Articles

EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity

Junli Yan, Siok-Bian Ng, Jim Liang-Seah Tay, Baohong Lin, Tze Loong Koh, Joy Tan, Viknesvaran Selvarajan, Shaw-Cheng Liu, Chonglei Bi, Shi Wang, Shoa-Nian Choo, Norio Shimizu, Gaofeng Huang, Qiang Yu, Wee-Joo Chng

Blood (2013) 121 (22): 4512–4520.

https://doi.org/10.1182/blood-2012-08-450494

Published: 2013

Includes: Supplemental data

Journal Articles

Epigenetic Silencing of the Receptor Tyrosine Phosphatase, PTPRK , Located At the Frequently Deleted 6q22.33-q23.2 Region, Leads to Tumor Growth Via the Constitutive Activation of STAT3 in Nasal-Type NK/T-Cell Lymphoma

Yun-Wen Chen, Tianhuan Guo, Lijun Shen, Kai-Yau Wong, Wing-Yan Au, MD, Qian Tao, Lok-Yi Wong, Cheuk-On Tang, Wai Lap Choi, Wei-Ping Liu, Gan-Di Li, Norio Shimizu, Junjiro Tsuchiyama, Florence Loong, Raymond Liang, MD, FRCP, Yok Lam Kwong, MD, Gopesh Srivastava, Ph.D

Blood (2011) 118 (21): 1378.

https://doi.org/10.1182/blood.V118.21.1378.1378

Published: 2011

Journal Articles

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma

Siok-Bian Ng, Junli Yan, Gaofeng Huang, Viknesvaran Selvarajan, Jim Liang-Seah Tay, Baohong Lin, Chonglei Bi, Joy Tan, Yok-Lam Kwong, Norio Shimizu, Katsuyuki Aozasa, Wee-Joo Chng

Blood (2011) 118 (18): 4919–4929.

https://doi.org/10.1182/blood-2011-07-364224

Published: 2011

Includes: Supplemental data

Journal Articles

Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses

Kennosuke Karube, Masao Nakagawa, Shinobu Tsuzuki, Ichiro Takeuchi, Keiichiro Honma, Yasuhiro Nakashima, Norio Shimizu, Young-Hyeh Ko, Yasuo Morishima, Koichi Ohshima, Shigeo Nakamura, Masao Seto

Blood (2011) 118 (12): 3195–3204.

https://doi.org/10.1182/blood-2011-04-346890

Published: 2011

Includes: Supplemental data

Journal Articles

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer–cell lymphoma/leukemia

Yasuo Yamanaka, Hiroyuki Tagawa, Naoto Takahashi, Atsushi Watanabe, Yong-Mei Guo, Keiko Iwamoto, Junsuke Yamashita, Hirobumi Saitoh, Yoshihiro Kameoka, Norio Shimizu, Ryo Ichinohasama, Ken-ichi Sawada

Blood (2009) 114 (15): 3265–3275.

https://doi.org/10.1182/blood-2009-06-222794

Published: 2009

Includes: Supplemental data

Journal Articles

Analysis of Gene Expression Patterns and Gene Copy Number Changes in Human NK Cell Malignancies.

Javeed Iqbal, PhD, Huimin Geng, M.Sc, Ronald J. DeLeeuw, M.Sc, Kavita Patel, M.D, Wan L. Lam, Ph.D, Karen Dybkaer, Ph.D, Norio Shimizu, M.D, Gopesh Srivastava, Ph.D, Wing-Chung Chan, M.D

Blood (2006) 108 (11): 2228.

https://doi.org/10.1182/blood.V108.11.2228.2228

Published: 2006

Journal Articles

Hematopoietic stem cell–engrafted NOD/SCID/IL2Rγ null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

Satoru Watanabe, Kazuo Terashima, Shinrai Ohta, Shigeo Horibata, Misako Yajima, Yoko Shiozawa, M. Zahidunnabi Dewan, Zhong Yu, Mamoru Ito, Tomohiro Morio, Norio Shimizu, Mitsuo Honda, Naoki Yamamoto

Blood (2006) 109 (1): 212–218.

https://doi.org/10.1182/blood-2006-04-017681

Published: 2006

Journal Articles

Transcriptional Profiling of Epstein-Barr Virus (EBV) Genes and Host Cellular Genes in Nasal NK/T-Cell Lymphoma and Chronic Active EBV Infection.

Yu Zhang, MD, Junko H. Ohyashiki, MD, Tomoiku Takaku, MD, Norio Shimizu, PhD, Kazuma Ohyashiki, MD

Blood (2005) 106 (11): 4359.

https://doi.org/10.1182/blood.V106.11.4359.4359

Published: 2005

Journal Articles

Aberrant BCL10 nuclear expression in nasal NK/T-cell lymphoma

Lijun Shen, Anthony C. T. Liang, Liwei Lu, Wing Y. Au, Kai-Yau Wong, Pui-Chi Tin, Kwok-Wah Chan, King-Hung Ko, Yun-Wen Chen, Swan-Lip Beh, Norio Shimizu, Junjiro Tsuchiyama, Johnny C. O. Tang, Yok-Lam Kwong, Raymond H. S. Liang, Gopesh Srivastava

Blood (2003) 102 (4): 1553–1554.

https://doi.org/10.1182/blood-2003-04-1286

Published: 2003

Journal Articles

Characterization of novel natural killer (NK)–cell and γδ T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus

Hiroshi Nagata, Akiyoshi Konno, Nobuhiro Kimura, Yu Zhang, Michiko Kimura, Ayako Demachi, Teruaki Sekine, Kohtaro Yamamoto, Norio Shimizu

Blood (2001) 97 (3): 708–713.

https://doi.org/10.1182/blood.V97.3.708

Published: 2001

NARROW

Phase II Study of a JAK1/2 Inhibitor Ruxolitinib for Systemic Chronic Active Epstein-Barr Virus Disease: An Investigator-Initiated Trial

Expression Profile of EBV-Derived Micro-RNA in Systemic Chronic Active EBV Disease

The Presence of Defective Epstein-Barr Virus (EBV) Infection in Patients with EBV-Associated Hematological Malignancy

Histone Deacetylase Inhibitors Downregulate CCR4 Expression and Decrease Mogamulizumab Efficacy in CCR4-Positive Mature T-Cell Lymphomas

Receptor-type tyrosine-protein phosphatase κ directly targets STAT3 activation for tumor suppression in nasal NK/T-cell lymphoma

Multiplex PCR for Virus Infections after Allogeneic Hematopoietic Stem Cell Transplantation

EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity

Epigenetic Silencing of the Receptor Tyrosine Phosphatase, PTPRK , Located At the Frequently Deleted 6q22.33-q23.2 Region, Leads to Tumor Growth Via the Constitutive Activation of STAT3 in Nasal-Type NK/T-Cell Lymphoma

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma

Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer–cell lymphoma/leukemia

Analysis of Gene Expression Patterns and Gene Copy Number Changes in Human NK Cell Malignancies.

Hematopoietic stem cell–engrafted NOD/SCID/IL2Rγ null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

Transcriptional Profiling of Epstein-Barr Virus (EBV) Genes and Host Cellular Genes in Nasal NK/T-Cell Lymphoma and Chronic Active EBV Infection.

Aberrant BCL10 nuclear expression in nasal NK/T-cell lymphoma

Characterization of novel natural killer (NK)–cell and γδ T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virus

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American Society of Hematology

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ASH Publications

American Society of Hematology

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