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Benjamin T. Kile, PhD
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Journal Articles

ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia

Cecile Thirant, PhD, Cecile K Lopez, Cathy Ignacimouttou, M'Boyba Diop, Lou Le Mouël, MD, Clarisse Thiollier, MD PhD, Aurelie Siret, Philippe Dessen, Zakia Aid, Julie Riviere, PhD, Philippe Rameau, Celine Lefebvre, Mehdi Khaled, PhD, Guy Leverger, MD, Paola Fabiola Ballerini, MDPhD, Arnaud Petit, MD PhD, Hana Raslova, PhD, Catherine Carmichael, Benjamin T. Kile, PhD, Eric Soler, PhD, John Crispino, PhD, Christian Wichmann, MD, Camille Lobry, PhD, Francoise Pfumio, PhD, Juerg Schwaller, MD, Nathalie M. Droin, PhD, William Vainchenker, MD PhD, Olivier A. Bernard, PhD, Sebastien Malinge, PhD, Thomas Mercher, PhD
Journal: Blood
Blood (2016) 128 (22): 572.
https://doi.org/10.1182/blood.V128.22.572.572
Published: 2016
Journal Articles

Mutations in Tropomyosin 4 Cause Macrothrombocytopenia in Mice and Humans

Irina Pleines, PhD, Joanne Woods, PhD, Ernest Turro, PhD, Nicola Foad, PhD, Stephane Chappaz, PhD, Rachael M. Lane, Harriet Manning, Galina Schevzov, PhD, Sarah K Westbury, Andrew D Mumford, Remi Favier, MD, Peter Gunning, PhD, Willem H. Ouwehand, MDPhDFRCPath FMedSci #, Marloes R Tijssen, PhD, Benjamin T Kile, PhD
Journal: Blood
Blood (2014) 124 (21): 571.
https://doi.org/10.1182/blood.V124.21.571.571
Published: 2014
Journal Articles

Radioulnar Synostosis-Hematology (RUS-H) Syndrome: Description of the New Syndrome and Comparison to Similar Syndromes

Evangelista E Jessie, BA, Mary M. Ruisi, MD, Daniel Green, MD, Rachel Burt, PhD, Jaclyn Davis, MD, Regina A. Macatangay, MD, Farid Boulad, MD, Shivani Shah, MBBS, Brenda Oiyemhonlan, MD, MPH, MHSA, Benjamin T. Kile, PhD, James B Bussel, MD
Journal: Blood
Blood (2012) 120 (21): 1100.
https://doi.org/10.1182/blood.V120.21.1100.1100
Published: 2012
Journal Articles

ENU Mutagenesis in the Mouse for Identification of Genes Regulating Erythropoiesis: a Mouse Mutant with An Activating Mutation of the KCl Cotransporter, KCC1 Causing Dehydrated Red Cells

David J. Curtis, MD, PhD, Fiona Brown, BSc, James Wiley, MD PhD, Shwen Ho, PhD, Douglas J. Hilton, PhD, Benjamin T. Kile, PhD, Stephen M Jane
Journal: Blood
Blood (2011) 118 (21): 684.
https://doi.org/10.1182/blood.V118.21.684.684
Published: 2011
Journal Articles

The Pan Histone Deacetylase Inhibitor Panobinostat and the Iso-Selective Inhibitor Romidepsin Reduce Glycoprotein VI Expression and Inhibit Platelet Activation in Response to Collagen Related Peptide

Mark J Bishton, Miles Prince, MD, FRACP, FRCPA, Ricky W Johnstone, PhD, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Benjamin T. Kile, PhD
Journal: Blood
Blood (2011) 118 (21): 1154.
https://doi.org/10.1182/blood.V118.21.1154.1154
Published: 2011
Journal Articles

The Effect of Eltrombopag on Platelet Resistance to Apoptosis: The Role of the Bcl-Xl Pathway

W. Beau Mitchell, MD, Michele N Edison, BS, Mariana P Pinheiro, MD, Nayla Boulad, BA, Bethan Psaila, MD, Marissa Karpoff, BS, Kaplan David, MD, Ph.D., Benjamin T. Kile, PhD, Michael J White, Emma C Josephson, James B Bussel, MD
Journal: Blood
Blood (2011) 118 (21): 1158.
https://doi.org/10.1182/blood.V118.21.1158.1158
Published: 2011
Journal Articles

The Effect of Eltrombopag on Human Platelet Resistance to Apoptosis: The Role of the Bcl-Xl Pathway

W. Beau Mitchell, MD, Michele N Edison, BS, Mariana P Pinheiro, MD, Nayla Boulad, BA, Bethan Psaila, MD, PhD, Marissa Karpoff, BS, David Kaplan, MD, Benjamin T Kile, PhD, Michael J White, Emma C Josefsson, James B. Bussel, MD
Journal: Blood
Blood (2010) 116 (21): 2520.
https://doi.org/10.1182/blood.V116.21.2520.2520
Published: 2010
Journal Articles

Overcoming Histone Deacetylase Inhibitor Induced Thrombocytopenia Using a Thrombopoietin Mimetic.

Mark J Bishton, Miles Prince, Simon Harrison, Ben P Martin, Bsc, (Hons), Chloé James, MD, PhD, Benjamin T. Kile, PhD, R. W Johnstone
Journal: Blood
Blood (2009) 114 (22): 2416.
https://doi.org/10.1182/blood.V114.22.2416.2416
Published: 2009
Journal Articles

Deletion of Bcl-X in the Megakaryocyte Compartment Results in Profound Thrombocytopenia Caused by Impaired Platelet Production and Survival.

Chloé James, MD, PhD, Emma C. Josefsson, PhD, Michael J. White, Katya J. Henley, Benjamin T. Kile, PhD
Journal: Blood
Blood (2009) 114 (22): 1495.
https://doi.org/10.1182/blood.V114.22.1495.1495
Published: 2009
Journal Articles

Platelet Death.

Emma C. Josefsson, PhD, Simone Schoenwaelder, PhD, Michael White, Matthew Goschnick, PhD, Andrew W. Roberts, PhD, Kylie D. Mason, PhD, Shaun Jackson, PhD, David C. Huang, Benjamin T. Kile, PhD
Journal: Blood
Blood (2008) 112 (11): sci-40.
https://doi.org/10.1182/blood.V112.11.sci-40.sci-40
Published: 2008
Journal Articles

The Bcl-2 Protein Family Is Essential for Platelet Survival In Vivo.

Kylie D. Mason, MBBS, Marina R. Carpinelli, PhD, Janelle E. Collinge, PhD, Adrienne A. Hilton, Jamie I. Fletcher, PhD, Andrew W. Roberts, MBBS,PhD, Donald Metcalf, MBBS, David C.S. Huang, MBBS,PhD, Benjamin T. Kile, PhD
Journal: Blood
Blood (2006) 108 (11): 697.
https://doi.org/10.1182/blood.V108.11.697.697
Published: 2006