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Journal Articles

Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88 L265P plasmablasts in vivo

James Q. Wang, Bruce Beutler, Christopher C. Goodnow, Keisuke Horikawa

Blood (2016) 128 (12): 1604–1608.

https://doi.org/10.1182/blood-2016-03-708065

Published: 2016

Includes: Supplemental data

Journal Articles

Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1

William S. Stevenson, David J. Rabbolini, Lucinda Beutler, Qiang Chen, Sara Gabrielli, Joel P. Mackay, Timothy A. Brighton, Christopher M. Ward, Marie-Christine Morel-Kopp

Blood (2015) 126 (17): 2027–2030.

https://doi.org/10.1182/blood-2015-06-650887

Published: 2015

Includes: Supplemental data

Journal Articles

iRhom2 is required for the secretion of mouse TNFα

Owen M. Siggs, Nengming Xiao, Ying Wang, Hexin Shi, Wataru Tomisato, Xiaohong Li, Yu Xia, Bruce Beutler

Blood (2012) 119 (24): 5769–5771.

https://doi.org/10.1182/blood-2012-03-417949

Published: 2012

Includes: Supplemental data

Journal Articles

Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice

Lara Krieg, Oren Milstein, Philippe Krebs, Yu Xia, Bruce Beutler, Xin Du

Blood (2011) 118 (24): 6418–6425.

https://doi.org/10.1182/blood-2011-04-350082

Published: 2011

Includes: Supplemental data

Journal Articles

Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice

Philippe Krebs, Karine Crozat, Daniel Popkin, Michael B. Oldstone, Bruce Beutler

Blood (2011) 117 (24): 6582–6588.

https://doi.org/10.1182/blood-2011-01-329607

Published: 2011

Includes: Supplemental data

Journal Articles

Impact of β2 integrin deficiency on mouse natural killer cell development and function

Karine Crozat, Céline Eidenschenk, Baptiste N. Jaeger, Philippe Krebs, Sophie Guia, Bruce Beutler, Eric Vivier, Sophie Ugolini

Blood (2011) 117 (10): 2874–2882.

https://doi.org/10.1182/blood-2010-10-315457

Published: 2011

Includes: Supplemental data

Journal Articles

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

Zane Orinska, Niko Föger, Michael Huber, Julia Marschall, Farhad Mirghomizadeh, Xin Du, Marina Scheller, Philip Rosenstiel, Torsten Goldmann, Annalena Bollinger, Bruce A. Beutler, Silvia Bulfone-Paus

Blood (2010) 116 (15): 2665–2675.

https://doi.org/10.1182/blood-2009-06-228460

Published: 2010

Includes: Supplemental data

Journal Articles

The Extent in Telomere Attrition and the Number of Affected Leukocyte Subsets Distinguishes Patients with Different Myeloproliferative Neoplasms (MPN).

Dirk de Beer, Elke Beutler, Adrian Emanuel Schmidt, Lucie Kopfstein, Elisabeth Oppliger Leibundgut, PharmD, PhD, Gabriela M. Baerlocher, MD

Blood (2009) 114 (22): 1913.

https://doi.org/10.1182/blood.V114.22.1913.1913

Published: 2009

Journal Articles

NK cell–mediated killing of target cells triggers robust antigen-specific T cell–mediated and humoral responses

Philippe Krebs, Michael J. Barnes, Kristin Lampe, Karen Whitley, Keith S. Bahjat, Bruce Beutler, Edith Janssen, Kasper Hoebe

Blood (2009) 113 (26): 6593–6602.

https://doi.org/10.1182/blood-2009-01-201467

Published: 2009

Includes: Supplemental data

Journal Articles

TLRs and innate immunity

Bruce A. Beutler

Blood (2009) 113 (7): 1399–1407.

https://doi.org/10.1182/blood-2008-07-019307

Published: 2009

Journal Articles

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

Jaroslav Truksa, Pauline Lee, Ernest Beutler

Blood (2009) 113 (3): 688–695.

https://doi.org/10.1182/blood-2008-05-160184

Published: 2009

Includes: Supplemental data

Journal Articles

Association of SMAD3/4, COUP-Tf, HNF4α, C/EBPα, GATA2 and STAT5 to the Hamp1 Promoter

Pauline Lee, PhD, Jaroslav Truksa, PhD, Ernest Beutler, MD

Blood (2008) 112 (11): 3837.

https://doi.org/10.1182/blood.V112.11.3837.3837

Published: 2008

Journal Articles

Inhibition of Hamp1 Expression by TMPRSS6, GDF15, PIAS4 and SMAD6 Utilize Several Target Sites in the Hamp1 Promoter

Jaroslav Truksa, PhD, Pauline Lee, PhD, Ernest Beutler, MD

Blood (2008) 112 (11): 3838.

https://doi.org/10.1182/blood.V112.11.3838.3838

Published: 2008

Journal Articles

Evidence for Increased Red Cell Turnover in Unexplained Anemia in Patients Over 70 Years of Age

Jeff Friedman, MD, PhD, Jill Waalen, MD, MPH, Alisa Takeda, Ernest Beutler, MD

Blood (2008) 112 (11): 3445.

https://doi.org/10.1182/blood.V112.11.3445.3445

Published: 2008

Journal Articles

Response: Screening for treatable disease is better than just screening for hemochromatosis

Jill Waalen, Vincent J. Felitti, Terri Gelbart, Ernest Beutler

Blood (2008) 111 (7): 3897.

https://doi.org/10.1182/blood-2008-01-132977

Published: 2008

Journal Articles

Screening for hemochromatosis by measuring ferritin levels: a more effective approach

Jill Waalen, Vincent J. Felitti, Terri Gelbart, Ernest Beutler

Blood (2008) 111 (7): 3373–3376.

https://doi.org/10.1182/blood-2007-07-102673

Published: 2008

Journal Articles

Glucose-6-phosphate dehydrogenase deficiency: a historical perspective

Ernest Beutler

Blood (2008) 111 (1): 16–24.

https://doi.org/10.1182/blood-2007-04-077412

Published: 2008

Journal Articles

Transcriptional Regulation of Hepcidin by Iron.

Pauline Lee, PhD, Truksa Jaroslav, Ph.D., Hongfan Peng, Ernest Beutler, M.D.

Blood (2007) 110 (11): 2664.

https://doi.org/10.1182/blood.V110.11.2664.2664

Published: 2007

Journal Articles

Screening for Hemochromatosis by Measuring Ferritin Levels: A More Effective Approach.

Jill Waalen, MD, MPH, Ernest Beutler, MD

Blood (2007) 110 (11): 2673.

https://doi.org/10.1182/blood.V110.11.2673.2673

Published: 2007

Journal Articles

The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron.

Ernest Beutler, MD, Pauline Lee, PhD, Terri Gelbart, BS, Xin Du, PhD, Bruce Beutler, MD

Blood (2007) 110 (11): 3.

https://doi.org/10.1182/blood.V110.11.3.3

Published: 2007

NARROW

Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88 L265P plasmablasts in vivo

Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1

iRhom2 is required for the secretion of mouse TNFα

Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice

Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice

Impact of β2 integrin deficiency on mouse natural killer cell development and function

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

The Extent in Telomere Attrition and the Number of Affected Leukocyte Subsets Distinguishes Patients with Different Myeloproliferative Neoplasms (MPN).

NK cell–mediated killing of target cells triggers robust antigen-specific T cell–mediated and humoral responses

TLRs and innate immunity

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

Association of SMAD3/4, COUP-Tf, HNF4α, C/EBPα, GATA2 and STAT5 to the Hamp1 Promoter

Inhibition of Hamp1 Expression by TMPRSS6, GDF15, PIAS4 and SMAD6 Utilize Several Target Sites in the Hamp1 Promoter

Evidence for Increased Red Cell Turnover in Unexplained Anemia in Patients Over 70 Years of Age

Response: Screening for treatable disease is better than just screening for hemochromatosis

Screening for hemochromatosis by measuring ferritin levels: a more effective approach

Glucose-6-phosphate dehydrogenase deficiency: a historical perspective

Transcriptional Regulation of Hepcidin by Iron.

Screening for Hemochromatosis by Measuring Ferritin Levels: A More Effective Approach.

The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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