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Michael Huber
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Journal Articles

The Unfolded Protein Response Mediates Resistance in AML and Its Therapeutic Targeting Enhances TKI Induced Cell Death in FLT3-ITD + AML

Free
Timo Jaquet, Christian Preisinger, Marlena Bütow, Stefan Tillmann, Nicolas Chatain, Michael Huber, Steffen Koschmieder, Martin Kirschner, Edgar Jost, Tim H Brümmendorf, Bezhad Kharabi, Iris Appelmann, Mirle Schemionek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2246.
https://doi.org/10.1182/blood-2021-150066
Published: 2021
Journal Articles

Interplay between PI3K/mTOR Signaling and IRE1a-XBP1 Promotes Survival of Pre-B NRAS G12D all Cells Providing a Therapeutic Vulnerability for the "Undruggable" Driver RAS

Free
Iris Appelmann, MD, Azam Salimi, Michael Huber, PhD, Mirle Schemionek, PhD, Margherita Vieri, PhD, Tim H Brümmendorf, MD, John B. Patterson, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140299
Published: 2020
Journal Articles

Differential Use of the Signaling Molecules BTK and PLC-γ in Mast Cells Stimulated Via the Receptors FcεRI and KIT

Free
Anne Simonowski, MD, Carolin Zorn, PhD, Michael Huber, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2270.
https://doi.org/10.1182/blood.V130.Suppl_1.2270.2270
Published: 2017
Journal Articles

Bcr-Abl1 Kinase-Independent Upregulation of FcγRIIb Mediates Malignant Signaling That Is Critical for Leukemogenesis

Free
Oliver Herrmann, Msc, Samantha Langer, Caroline Wessling, Michael Huber, PhD, Shaoguang Li, MD PhD, Tim Henrik Bruemmendorf, Steffen Koschmieder, Mirle Schemionek, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2862.
https://doi.org/10.1182/blood.V130.Suppl_1.2862.2862
Published: 2017
Journal Articles

Genetic Depletion of Fc Gamma Receptor 2b Affects CML Stem Cell Biology

Free
Oliver Herrmann, MSc, Caroline CA Weßling, MD, Michael Huber, PhD, Shaoguang Li, MD PhD, Tim H. Brümmendorf, MD, Steffen Koschmieder, MD, Mirle Schemionek, PhD
Journal: Blood
Blood (2014) 124 (21): 4528.
https://doi.org/10.1182/blood.V124.21.4528.4528
Published: 2014
Journal Articles

Durable Responses with the JAK1/ JAK2 Inhibitor, INCB018424, In Patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET) Refractory or Intolerant to Hydroxyurea (HU)

Free
Srdan Verstovsek, MD, PhD, Francesco Passamonti, Alessandro Rambaldi, MD, Giovanni Barosi, MD, Peter J. Rosen, MD, Richard Levy, Edward Bradley, William Garrett, Kris Vaddi, Nancy Contel, Victor Sandor, Reid Michael Huber, PhD, Lee P. Schacter, MD, PhD, Elisa Rumi, Elisabetta Gattoni, Elisabetta Antonioli, Lisa Pieri, MD, Mario Cazzola, MD, Hagop Kantarjian, MD, Tiziano Barbui, MD, Alessandro M. Vannucchi, MD
Journal: Blood
Blood (2010) 116 (21): 313.
https://doi.org/10.1182/blood.V116.21.313.313
Published: 2010
Journal Articles

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

Free
Zane Orinska, Niko Föger, Michael Huber, Julia Marschall, Farhad Mirghomizadeh, Xin Du, Marina Scheller, Philip Rosenstiel, Torsten Goldmann, Annalena Bollinger, Bruce A. Beutler, Silvia Bulfone-Paus
Journal: Blood
Blood (2010) 116 (15): 2665–2675.
https://doi.org/10.1182/blood-2009-06-228460
Published: 2010
Includes: Supplemental data