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Journal Articles

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1

Le Xuan Truong Nguyen, Yunqin Lee, Lenore Urbani, Paul J. Utz, Anne W. Hamburger, John B. Sunwoo, Beverly S. Mitchell

Blood (2015) 125 (16): 2519–2529.

https://doi.org/10.1182/blood-2014-12-616433

Published: 2015

Includes: Supplemental data

Journal Articles

Preclinical Activity of a New Proteasome Inhibitor, MLN9708, in Acute Myelogenous Leukemias Expressing NPM1 Mutated Protein

Jacqueline S Garcia, MD, Min Huang, Bruno C Medeiros, MD, Beverly S. Mitchell, MD

Blood (2014) 124 (21): 993.

https://doi.org/10.1182/blood.V124.21.993.993

Published: 2014

Journal Articles

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells

Le Xuan Truong Nguyen, Steven M. Chan, Tri Duc Ngo, Aparna Raval, Kyeong Kyu Kim, Ravindra Majeti, Beverly S. Mitchell

Blood (2014) 124 (4): 579–589.

https://doi.org/10.1182/blood-2013-12-544726

Published: 2014

Includes: Supplemental data

Journal Articles

The ASH Clinical Research Training Institute (CRTI) Positively Impacts The Success Of Early Career Hematologists In Patient-Oriented Clinical Research

Linda J Burns, MD, Charles P Clayton, James N. George, MD, Beverly S. Mitchell, Scott D. Gitlin, MD

Blood (2013) 122 (21): 1679.

https://doi.org/10.1182/blood.V122.21.1679.1679

Published: 2013

Journal Articles

Activation Of Akt Enhances Ribosomal RNA Synthesis In AML Cells Through a Novel Isoform Of TIF-1A and Inhibition Of Filamin A Cleavage

Le Xuan Truong Nguyen, PhD, Min Huang, Steven M. Chan, MD, PhD, Ravi Majeti, MD, PhD, Beverly S. Mitchell

Blood (2013) 122 (21): 1266.

https://doi.org/10.1182/blood.V122.21.1266.1266

Published: 2013

Journal Articles

Are Racial and Ethnic Disparities In Acute Myeloid Leukemia Due To Differences In Treatment?

Manali I. Patel, MD, MPH, Yifei Ma, MS, Beverly S. Mitchell, Kim Rhoads, MS MD MPH

Blood (2013) 122 (21): 726.

https://doi.org/10.1182/blood.V122.21.726.726

Published: 2013

Journal Articles

Reduced rRNA expression and increased rDNA promoter methylation in CD34 + cells of patients with myelodysplastic syndromes

Aparna Raval, Kunju J. Sridhar, Shripa Patel, Brit B. Turnbull, Peter L. Greenberg, Beverly S. Mitchell

Blood (2012) 120 (24): 4812–4818.

https://doi.org/10.1182/blood-2012-04-423111

Published: 2012

Includes: Supplemental data

Journal Articles

Are Disparities in Acute Myelogenous Leukemia Due to Poor Prognostic Factors At Diagnosis? A National Study

Manali I. Patel, MD, MPH, Yifei Ma, MS, Beverly S. Mitchell, Kim Rhoads, MS MD MPH

Blood (2012) 120 (21): 2061.

https://doi.org/10.1182/blood.V120.21.2061.2061

Published: 2012

Journal Articles

Cysteine 288 Regulates NPMc+ Cytoplasmic Localization and Sensitizes Leukemic Cells to Bortezomib-Induced Apoptosis Through a Redox-Sensitive Mechanism

Min Huang, Xinran Li, Beverly S. Mitchell

Blood (2012) 120 (21): 532.

https://doi.org/10.1182/blood.V120.21.532.532

Published: 2012

Journal Articles

Reactivation of Telomerase in Late Generation Tert−/− Mice Results in Reversal of Anemia

Aparna Raval, PhD, Brenda Kusler, BS, Alina Garbuzov, BS, Steven Artandi, MD, PhD, Beverly S. Mitchell

Blood (2012) 120 (21): 1258.

https://doi.org/10.1182/blood.V120.21.1258.1258

Published: 2012

Journal Articles

Defective Hematopoiesis and Erythroid Differentiation Resulting From Telomerase Deficiency

Aparna Raval, PhD, Brenda Kusler, BS, Steven Artandi, MD, PhD, Beverly S. Mitchell, MD

Blood (2011) 118 (21): 2410.

https://doi.org/10.1182/blood.V118.21.2410.2410

Published: 2011

Journal Articles

A Novel Missense Mutation In An MDS Patient and Effects on TET2 mRNA Expression and Clinical Outcomes

Daniel A Pollyea, MD, Aparna Raval, PhD, Brenda Kusler, Jason R Gotlib, MD, MS, Ash A. Alizadeh, MD, PhD, Beverly S. Mitchell, MD

Blood (2010) 116 (21): 1889.

https://doi.org/10.1182/blood.V116.21.1889.1889

Published: 2010

Journal Articles

Ribosomal RNA Expression In CD34+ Hematopoietic Progenitor Cells Inversely Correlates with Ribosomal DNA Methylation In Myelodysplastic Syndromes.

Aparna Raval, PhD, Daniel A Pollyea, MD, Kunju J Shridhar, PhD, Shripa Patel, Peter L. Greenberg, MD, Beverly S. Mitchell, MD

Blood (2010) 116 (21): 1682.

https://doi.org/10.1182/blood.V116.21.1682.1682

Published: 2010

Journal Articles

A Phase I Study of Sequential Azacitidine and Lenalidomide for Elderly Patients with Acute Myeloid Leukemia (AML)

Daniel A Pollyea, MD, Holbrook E Kohrt, MD, Leonel Gallegos, MD, Caroline Berube, MD, Steven Coutre, MD, Jason Gotlib, M.D., M.S., Michaela Liedtke, MD, Beverly S. Mitchell, MD, Bruno C. Medeiros, MD

Blood (2010) 116 (21): 3288.

https://doi.org/10.1182/blood.V116.21.3288.3288

Published: 2010

Journal Articles

NPM1 Haploinsufficiency Results in Increased Numbers of Hematopoietic Stem Cells and Progenitor Cells.

Aparna Raval, Christopher Y. Park, Wendy W Pang, Brenda Kusler, Kunju Joshi Sridhar, Jason R Gotlib, Peter L Greenberg, Irving L. Weissman, Beverly S. Mitchell

Blood (2009) 114 (22): 738.

https://doi.org/10.1182/blood.V114.22.738.738

Published: 2009

Journal Articles

Clinical-Biomarker Correlations in Adult AML Patients in a Phase I Trial of AVN944 Support Observations of Clinical Effect and Provide Hypotheses for Patient Selection Criteria for Further Clinical Trials.

Rebecca B. Klisovic, MD, Steven Coutre, MD, Tibor J. Kovacsovics, MD, Hagop M. Kantarjiam, MD, Guido J. Tricot, MD, Jeffrey W. Strovel, PhD, Thomas Genna, RhP, David K. Bol, PhD, Michael Hamilton, MD, Beverly S. Mitchell, MD

Blood (2007) 110 (11): 896.

https://doi.org/10.1182/blood.V110.11.896.896

Published: 2007

Journal Articles

Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801

Daniel J. DeAngelo, Daohai Yu, Jeffrey L. Johnson, Steven E. Coutre, Richard M. Stone, Alison T. Stopeck, Jon P. Gockerman, Beverly S. Mitchell, Frederick R. Appelbaum, Richard A. Larson

Blood (2007) 109 (12): 5136–5142.

https://doi.org/10.1182/blood-2006-11-056754

Published: 2007

Journal Articles

Genetic and Biochemical Biomarkers of IMPDH Inhibition in Phase I Dose Escalation of AVN-944 for Hematologic Malignancies.

Jeffrey W. Strovel, PhD, Marion Chakiath, M.S, Pachai Natarajan, M.S., Tammy Lawrence, M.S., Karina M. Zuck, Ph.D., Lenore Urbani, Ph.D., Beverly S. Mitchell, M.D., David K. Bol, Ph.D.

Blood (2006) 108 (11): 2590.

https://doi.org/10.1182/blood.V108.11.2590.2590

Published: 2006

Journal Articles

Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies

Blood (2005) 105 (8): 3058–3065.

https://doi.org/10.1182/blood-2004-07-2911

Published: 2005

Journal Articles

Synergy between imatinib and mycophenolic acid in inducing apoptosis in cell lines expressing Bcr-Abl

Jing Jin Gu, Lalaine Santiago, Beverly S. Mitchell

Blood (2005) 105 (8): 3270–3277.

https://doi.org/10.1182/blood-2004-10-3864

Published: 2005

NARROW

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1

Preclinical Activity of a New Proteasome Inhibitor, MLN9708, in Acute Myelogenous Leukemias Expressing NPM1 Mutated Protein

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells

The ASH Clinical Research Training Institute (CRTI) Positively Impacts The Success Of Early Career Hematologists In Patient-Oriented Clinical Research

Activation Of Akt Enhances Ribosomal RNA Synthesis In AML Cells Through a Novel Isoform Of TIF-1A and Inhibition Of Filamin A Cleavage

Are Racial and Ethnic Disparities In Acute Myeloid Leukemia Due To Differences In Treatment?

Reduced rRNA expression and increased rDNA promoter methylation in CD34 + cells of patients with myelodysplastic syndromes

Are Disparities in Acute Myelogenous Leukemia Due to Poor Prognostic Factors At Diagnosis? A National Study

Cysteine 288 Regulates NPMc+ Cytoplasmic Localization and Sensitizes Leukemic Cells to Bortezomib-Induced Apoptosis Through a Redox-Sensitive Mechanism

Reactivation of Telomerase in Late Generation Tert−/− Mice Results in Reversal of Anemia

Defective Hematopoiesis and Erythroid Differentiation Resulting From Telomerase Deficiency

A Novel Missense Mutation In An MDS Patient and Effects on TET2 mRNA Expression and Clinical Outcomes

Ribosomal RNA Expression In CD34+ Hematopoietic Progenitor Cells Inversely Correlates with Ribosomal DNA Methylation In Myelodysplastic Syndromes.

A Phase I Study of Sequential Azacitidine and Lenalidomide for Elderly Patients with Acute Myeloid Leukemia (AML)

NPM1 Haploinsufficiency Results in Increased Numbers of Hematopoietic Stem Cells and Progenitor Cells.

Clinical-Biomarker Correlations in Adult AML Patients in a Phase I Trial of AVN944 Support Observations of Clinical Effect and Provide Hypotheses for Patient Selection Criteria for Further Clinical Trials.

Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801

Genetic and Biochemical Biomarkers of IMPDH Inhibition in Phase I Dose Escalation of AVN-944 for Hematologic Malignancies.

Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies

Synergy between imatinib and mycophenolic acid in inducing apoptosis in cell lines expressing Bcr-Abl

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