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Journal Articles

Pregnancy-Related Outcomes in Patients with Congenital Thrombotic Thrombocytopenic Purpura: Post Hoc Analysis of a Retrospective Chart Review Study

PAUL Coppo, Marie Scully, Johanna A. Kremer Hovinga, Maria Jose Aragon, Parth Patwari, Linda T. Wang, Bjorn Mellgard, Olulade Ayodele, Ragy Saad
Journal: Blood
Blood (2023) 142 (Supplement 1): 1261.
https://doi.org/10.1182/blood-2023-189181
Published: 2023
Journal Articles

Clinical Outcomes of Congenital Thrombotic Thrombocytopenic Purpura: A Multinational Chart Review Study

PAUL Coppo, Marie Scully, Johanna A. Kremer Hovinga, Maria Jose Aragon, Parth Patwari, Linda T. Wang, Bjorn Mellgard, Olulade Ayodele, Ragy Saad
Journal: Blood
Blood (2023) 142 (Supplement 1): 4006.
https://doi.org/10.1182/blood-2023-189416
Published: 2023
Journal Articles

Recombinant ADAMTS13 for the Treatment of Acute TTP Events in Patients with Congenital Thrombotic Thrombocytopenic Purpura: Results from the Phase 3 Randomized, Controlled, Crossover Study and the Phase 3b Continuation Study

Marie Scully, Thomas L. Ortel, Ziqiang Yu, Maria Waliullah, Pinghai Zhang, Munjal Patel, Parth Patwari, Bjorn Mellgard, Linda T. Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 692.
https://doi.org/10.1182/blood-2023-188996
Published: 2023
Journal Articles

Quantitative System Pharmacology Modeling of the Effect of Recombinant ADAMTS13 on Platelets in Patients with Congenital Thrombotic Thrombocytopenic Purpura

Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5517.
https://doi.org/10.1182/blood-2023-189558
Published: 2023
Journal Articles

Safety and Pharmacokinetics of Recombinant ADAMTS13 in Patients with Sickle Cell Disease: A Phase 1 Randomized, Double-Blind, Placebo-Controlled Study

Julie Kanter, Parth Patwari, Payal Desai, Kenneth I. Ataga, Shelley E. Crary, Sophie Lanzkron, Joshua Field, Yu-Che Chung, Linda T. Wang, Björn Mellgård, Van Anh (Vika) Nguyen, Victor R. Gordeuk
Journal: Blood
Blood (2023) 142 (Supplement 1): 149.
https://doi.org/10.1182/blood-2023-189090
Published: 2023
Journal Articles

Population Pharmacokinetics and Exposure-Response Analyses to Demonstrate the Link of Causality between ADAMTS13 and the Clinical Effects of Recombinant ADAMTS13 Compared to Plasma-Based Therapies

Munjal Patel, Olivier Barriere, Paul Diderichsen, Huijuan Xu, Andy Zhu, Jean François Marier, Björn Mellgård, Wenping Wang, Indranil Bhattacharya
Journal: Blood
Blood (2023) 142 (Supplement 1): 1260.
https://doi.org/10.1182/blood-2023-189314
Published: 2023
Journal Articles

Recombinant von Willebrand factor prophylaxis in patients with severe von Willebrand disease: phase 3 study results

Clinical Trials & Observations
Frank W. G. Leebeek, Flora Peyvandi, Miguel Escobar, Andreas Tiede, Giancarlo Castaman, Michael Wang, Tung Wynn, Jovanna Baptista, Yi Wang, Jingmei Zhang, Björn Mellgård, Gülden Özen
Journal: Blood
Blood (2022) 140 (2): 89–98.
https://doi.org/10.1182/blood.2021014810
Published: 2022
Includes: Supplemental data
Journal Articles

Exposure-Response Relationship between Von Willebrand Factor (VWF) Activity and Bleeding Events Following Prophylaxis with Recombinant VWF (rVWF, vonicog alfa) in Patients with Severe Von Willebrand Disease (VWD)

Yi Wang, Gülden Özen, Björn Mellgård, Jean Francois Marier, Olivier Barriere, Grygoriy Vasilinin, Indranil Bhattacharya
Journal: Blood
Blood (2021) 138 (Supplement 1): 2104.
https://doi.org/10.1182/blood-2021-146153
Published: 2021