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Journal Articles

Population Pharmacokinetics and Exposure-Response Analyses to Demonstrate the Link of Causality between ADAMTS13 and the Clinical Effects of Recombinant ADAMTS13 Compared to Plasma-Based Therapies

Munjal Patel, Olivier Barriere, Paul Diderichsen, Huijuan Xu, Andy Zhu, Jean François Marier, Björn Mellgård, Wenping Wang, Indranil Bhattacharya

Blood (2023) 142 (Supplement 1): 1260.

https://doi.org/10.1182/blood-2023-189314

Published: 2023

Journal Articles

Quantitative System Pharmacology Modeling of the Effect of Recombinant ADAMTS13 on Platelets in Patients with Congenital Thrombotic Thrombocytopenic Purpura

Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Zhu

Blood (2023) 142 (Supplement 1): 5517.

https://doi.org/10.1182/blood-2023-189558

Published: 2023

Journal Articles

Exposure-Response Relationship between Von Willebrand Factor (VWF) Activity and Bleeding Events Following Prophylaxis with Recombinant VWF (rVWF, vonicog alfa) in Patients with Severe Von Willebrand Disease (VWD)

Yi Wang, Gülden Özen, Björn Mellgård, Jean Francois Marier, Olivier Barriere, Grygoriy Vasilinin, Indranil Bhattacharya

Blood (2021) 138 (Supplement 1): 2104.

https://doi.org/10.1182/blood-2021-146153

Published: 2021

Journal Articles

Recombinant ADAMTS13 for Patients with Sickle Cell Disease: Design of a Phase 1 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study

Parth Patwari, Van Anh (Vika) Nguyen, Indranil Bhattacharya, Nisha Jain

Blood (2021) 138 (Supplement 1): 3118.

https://doi.org/10.1182/blood-2021-146150

Published: 2021