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Charles Phelps
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Journal Articles

Pooled Exposure-Response (ER) and Quantitative Benefit/Risk (B/R) Analyses Support the Approved Copanlisib Intermittent Dosing Regimen

Peter N Morcos, Jonathan Moss, Charles Phelps, Florian JR Hiemeyer, Barrett H. Childs, Martin Dreyling, Pier Luigi Zinzani, Dirk Garmann
Journal: Blood
Blood (2023) 142 (Supplement 1): 6156.
https://doi.org/10.1182/blood-2023-187153
Published: 2023
Journal Articles

Pooled Safety Analysis from Phase I-III Studies for Patients with Hematological Malignancies Treated with the PI3K Inhibitor Copanlisib

Pier Luigi Zinzani, Muhit Özcan, Marcelo Capra, Armando Santoro, Panayiotis Panayiotidis, Krimo Bouabdallah, Wojciech Jurczak, Charles Phelps, Florian JR Hiemeyer, Lidia Mongay Soler, Jose Garcia-Vargas, Barrett H. Childs, Georg Lenz, Matthew J. Matasar, Martin Dreyling
Journal: Blood
Blood (2022) 140 (Supplement 1): 6470–6473.
https://doi.org/10.1182/blood-2022-167368
Published: 2022
Journal Articles

11q Deletion (del11q) Is Not a Prognostic Factor for Adverse Outcomes for Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Treated with Ibrutinib: Pooled Data from 3 Randomized Phase 3 Studies

Thomas J. Kipps, MD, PhD, Peter Hillmen, Fatih Demirkan, MD, Sebastian Grosicki, MD PhD, Steven E. Coutre, MD, Jacqueline C. Barrientos, MD, Paul M. Barr, Ann Janssens, MD, John C. Byrd, MD, Susan M. O'Brien, MD, Graeme Fraser, MD, Ulrich Jaeger, MD, Paula Cramer, MD, Stephan Stilgenbauer, MD, Asher A. Chanan-Khan, MD, Mariya Salman, PhD, Isabelle Solman, MS, Mei Cheng, PhD, Charles Phelps, MSc, Joi Ninomoto, PharmD, Angela Howes, Danelle F. James, MD MAS, Michael Hallek
Journal: Blood
Blood (2016) 128 (22): 2042.
https://doi.org/10.1182/blood.V128.22.2042.2042
Published: 2016
Journal Articles

Early Changes in Circulating T-Cell Immune Profiles in Patients with Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Data from the Phase 3, Double-Blind HELIOS Trial

Rajendra Damle, PhD, Michael Schaffer, PhD, Shalini Chaturvedi, PhD, Charles Phelps, MSc, Regina Aquino, MSc, Michelle Mahler, MD, Mariya Salman, PhD, Angela Howes, PhD, Javier Loscertales, MD PhD, Marek Trneny, MD, Dina Ben Yehuda, MD, Alexander Pristupa, MD, Asher A. Chanan-Khan, MD, Sriram Balasubramanian, PhD
Journal: Blood
Blood (2016) 128 (22): 4397.
https://doi.org/10.1182/blood.V128.22.4397.4397
Published: 2016
Journal Articles

Impact of High Risk Prognostic Parameters and Addition of Ibrutinib to Bendamustine/Rituximab (BR) on Outcomes for Patients with Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) from the Phase 3 Double-Blind HELIOS Trial

Asher Chanan-Khan, MD, Paula Cramer, MD, Graeme Fraser, MDFRCPC, Rodrigo Santucci Silva, MD, Sebastian Grosicki, MD PhD, Aleksander Pristupa, MD, Marie Sarah Dilhuydy, MD, Andre Goy, MD, Anthony R. Mato, MD MSCE, Rajendra Damle, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Michael Schaffer, PhD, Angela Howes, PhD, Sriram Balasubramanian, PhD
Journal: Blood
Blood (2015) 126 (23): 1732.
https://doi.org/10.1182/blood.V126.23.1732.1732
Published: 2015
Journal Articles

Improvement of Quality of Response with Ibrutinib Plus Bendamustine/Rituximab Vs Placebo Plus Bendamustine/Rituximab for Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Paula Cramer, MD, Asher Chanan-Khan, MD, Graeme Fraser, MDFRCPC, Fatih Demirkan, MD, Rodrigo Santucci Silva, MD, Halyna Pylypenko, MD, Sebastian Grosicki, MD PhD, Ann Janssens, MD, Andre Goy, MD, Jiri Mayer, Prof., MD, Marie Sarah Dilhuydy, MD, Javier Loscertales, MD PhD, Nancy L. Bartlett, MD, Abraham Avigdor, MD, Simon Rule, MD, Steven Sun, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Michael Schaffer, PhD, Sriram Balasubramanian, PhD, Angela Howes, PhD, Michael Hallek, MD
Journal: Blood
Blood (2015) 126 (23): 2938.
https://doi.org/10.1182/blood.V126.23.2938.2938
Published: 2015
Journal Articles

Insights into the Management of Adverse Events in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Experience from the Phase 3 HELIOS Study of Ibrutinib Combined with Bendamustine/Rituximab

Asher Chanan-Khan, MD, Paula Cramer, MD, Fatih Demirkan, MD, Graeme Fraser, MDFRCPC, Rodrigo Santucci Silva, MD, Halyna Pylypenko, MD, Sebastian Grosicki, MD PhD, Ann Janssens, MD, Aleksander Pristupa, MD, Andre Goy, MD, Jiri Mayer, Prof., MD, Marie Sarah Dilhuydy, MD, Javier Loscertales, MD PhD, Nancy L. Bartlett, MD, Abraham Avigdor, MD, Simon Rule, MD, Steven Sun, PhD, Charles Phelps, MS, Michelle Mahler, MD, Mariya Salman, PhD, Angela Howes, PhD, Michael Hallek, MD
Journal: Blood
Blood (2015) 126 (23): 2936.
https://doi.org/10.1182/blood.V126.23.2936.2936
Published: 2015
Journal Articles

Phase 1b Dose Escalation Study Of Oral Quisinostat, a Histone Deacetylase Inhibitor (HDACi), In Combination With Velcade (Bortezomib) and Dexamethasone For Patients With Relapsed Multiple Myeloma (MM)

Philippe Moreau, MD, Thierry Facon, MD, Cyrille Touzeau, MD, Lotfi Benboubker, MD, Martine Delain, MD, Julie Badamo-Dotzis, PhD, Charles Phelps, Christopher Doty, Hans Smit, PhD, Nele Fourneau, MD, Ann Forslund, Peter Hellemans, MD, Xavier Leleu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1932.
https://doi.org/10.1182/blood.V122.21.1932.1932
Published: 2013
Journal Articles

Phase 2 Multicenter Trial of Oral Quisinostat, a Histone Deacetylase Inhibitor, in Patients with Previously Treated Stage IB-IVA Cutaneous T-Cell Lymphoma

Fiona Child, MD, Pablo Ortiz Romero, Prof., Rute Alvarez, MD, Martine Bagot, Rudolf Stadler, MD, Michael Weichenthal, MD, Rosario Alves, MD, Maria Grazia Bernengo, Prof., Marie Beylot-Barry, Prof., Richard Cowan, Larisa J. Geskin, MD, Amparo Pérez Ferriols, Peter Hellemans, MD, Yusri Elsayed, MD, PhD, Charles Phelps, Ann Forslund, Makio Kamida, Pier Luigi Zinzani, MD
Journal: Blood
Blood (2012) 120 (21): 3676.
https://doi.org/10.1182/blood.V120.21.3676.3676
Published: 2012