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Christopher G. Skipwith
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Journal Articles

Crystal Structure of a Proteolytic Fragment of ADAMTS13 Reveals Alternative Disulfide Pairings in the Cysteine-Rich Domain

Christopher G. Skipwith, BS, Steven Stayrook, PhD, Hanspeter Rottensteiner, PhD, Friedrich Scheiflinger, PhD, X. Long Zheng, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3363.
https://doi.org/10.1182/blood.V120.21.3363.3363
Published: 2012
Journal Articles

Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

Cui Jian, Juan Xiao, Lingjie Gong, Christopher G. Skipwith, Sheng-Yu Jin, Hau C. Kwaan, X. Long Zheng
Journal: Blood
Blood (2012) 119 (16): 3836–3843.
https://doi.org/10.1182/blood-2011-12-399501
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

Infusion of Recombinant Full-Length ADAMTS13 and Carboxyl-Terminal Truncated Variant Alters Composition of Ferric Chloride-Induced Arterial Thrombi in Adamts13 −/− mice

Christopher G. Skipwith, Juan (Jenny) Xiao, M.D., Ph.D., John W. Weisel, Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2313.
https://doi.org/10.1182/blood.V118.21.2313.2313
Published: 2011
Journal Articles

Gain-of-Function ADAMTS13 Variants Resistant to Anti-ADAMTS13 Autoantibody Inhibition: A Potential Novel Therapy for Acquired Autoimmune Thrombotic Thrombocytopenic Purpura

Cui Jian, M.S., Juan (Jenny) Xiao, M.D., Ph.D., Lingjie Gong, M.D., Christopher G. Skipwith, Sheng-Yu Jin, M.D., Ph.D., Hau C. Kwaan, M.D., Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1188.
https://doi.org/10.1182/blood.V118.21.1188.1188
Published: 2011
Journal Articles

Amino acid residues Arg 659 , Arg 660 , and Tyr 661 in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor

Sheng-Yu Jin, Christopher G. Skipwith, X. Long Zheng
Journal: Blood
Blood (2010) 115 (11): 2300–2310.
https://doi.org/10.1182/blood-2009-07-235101
Published: 2010
Journal Articles

Compromised Proteolytic Cleavage of Von Willebrand Factor Type 2N Variants by ADAMTS13 in the Presence of Factor VIII (and Platelets) Under Fluid Shear Stress.

Christopher G. Skipwith, Sandra L. Haberichter, Ph.D., Wenjing Cao, M.D., Ph.D., Ashley L. Gehrand, X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 28.
https://doi.org/10.1182/blood.V114.22.28.28
Published: 2009
Journal Articles

Proteolytic Cleavage of Endothelial Cell-Bound Von Willebrand Factor Polymers by ADAMTS13 in the Absence of Flow Shear Stress

Shengyu Jin, Christopher G. Skipwith, Dezhi Shang, Chandrasekaran Nagaswami, John W. Weisel, X. Long Zheng
Journal: Blood
Blood (2008) 112 (11): 3913.
https://doi.org/10.1182/blood.V112.11.3913.3913
Published: 2008
Journal Articles

Factor VIII and Platelets Cooperatively Accelerate Proteolytic Cleavage of Von Willebrand Factor by ADAMTS13 Under Shear Stress

Christopher G. Skipwith, Wenjing Cao, X. Long Zheng
Journal: Blood
Blood (2008) 112 (11): 590.
https://doi.org/10.1182/blood.V112.11.590.590
Published: 2008