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Christopher McKinney
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Journal Articles

Reduced intensity haploidentical bone marrow transplantation in children with severe sickle cell disease (SCD): BMT CTN 1507

Free
Mark Walters, Adetola Kassim, Mary Eapen, Jordan Milner, Robert Nickel, Alfred Gillio, Khaled Yassine, Jodi Skiles, Christopher McKinney, Hemalatha Rangarajan, Ghada Abusin, Jorge Galvez Silva, Michael Kent, Nicole Ritzau, Adam Mendizabal, Kris Mahadeo, Lakshmanan Krishnamurti, Kenneth Cooke, Eric Leifer, Rick Jones, Robert Brodsky, Michael DeBaun
Journal: Blood
Blood (2025) 146 (Supplement 1): 164.
https://doi.org/10.1182/blood-2025-164
Published: 2025
Journal Articles

CRISPR-Cas12a gene editing of the HBG1/2 promoters leads to sustained normalization of total hemoglobin and increased fetal hemoglobin in patients with severe sickle cell disease: Updated Results from the RUBY trial

Free
Rabi Hanna, Haydar Frangoul, Luis Pineiro, Christopher McKinney, Markus Mapara, Jignesh Dalal, Hemalatha Rangarajan, Harold Atkins, Monica Bhatia, Deepakbabu Chellapandian, Jennifer Jaroscak, Lakshmanan Krishnamurti, Janet Kwiatkowski, Lyndsay Molinari, Elizabeth Stenger, Michael Jaskolka, Qifeng Yu, Nnenna Badamosi, Brieana Cox-Buckley, Baisong Mei, Olubunmi Afonja, Mark Walters
Journal: Blood
Blood (2025) 146 (Supplement 1): 4314.
https://doi.org/10.1182/blood-2025-4314
Published: 2025
Journal Articles

Duffy Antigen Status, Hydroxyurea Dosing, and Phenotype Severity in Pediatric Patients with Sickle Cell Disease

Free
Alison Celello, Christopher McKinney
Journal: Blood
Blood (2024) 144 (Supplement 1): 5336.
https://doi.org/10.1182/blood-2024-209453
Published: 2024
Journal Articles

Reni-Cel, an Investigational AsCas12a Gene-Edited Cell Medicine, Led to Sustained Hemoglobin Normalization and Increased Fetal Hemoglobin in Patients with Severe Sickle Cell Disease Treated in the RUBY Trial

Free
Rabi Hanna, Haydar Frangoul, Christopher McKinney, Luis Pineiro, Markus Mapara, Jignesh Dalal, Hemalatha Rangarajan, Harold Atkins, Kai-Hsin Chang, Baisong Mei, Olubunmi Afonja, Mark C. Walters
Journal: Blood
Blood (2024) 144 (Supplement 1): 4955.
https://doi.org/10.1182/blood-2024-210343
Published: 2024
Journal Articles

Reduced Intensity Haploidentical Bone Marrow Transplantation in Adults with Severe Sickle Cell Disease: BMT CTN 1507

Free
Adetola A. Kassim, Mark C. Walters, Mary Eapen, Nicole Ritzau, Madoc Smith, Melhem M. Solh, Christopher McKinney, Michael Nieder, Maureen Ross, Michael Kent, Ghada Abusin, Kanwaldeep K. Mallhi, Jorge Galvez Silva, Paul Shaughnessy, Julie Kanter, Hilary Haines, Rafic J Farah, Yasser Khaled, Allistair Abraham, Catherine M. Bollard, Kenneth R. Cooke, Josu de La Fuente, Rabi Hanna, Mary M. Horowitz, Lori C Jordan, Lakshmanan Krishnamurti, Eric Leifere, Kris Michael Mahadeo, Shalini Shenoy, Nicole M. Ritzau, Michael R. DeBaun, Robert A. Brodsky
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2023-192022
Published: 2023
Journal Articles

AsCas12a Gene Editing of HBG1/2 Promoters with EDIT-301 Results in Rapid and Sustained Normalization of Hemoglobin and Increased Fetal Hemoglobin in Patients with Severe Sickle Cell Disease and Transfusion-Dependent Beta-Thalassemia

Free
Rabi Hanna, Haydar Frangoul, Christopher McKinney, Luis Pineiro, Markus Mapara, Jignesh Dalal, Kai-Hsin Chang, Michael Jaskolka, Keunpyo Kim, Daphne L. Farrington, Maha Wally, Baisong Mei, Adebayo Lawal, Olubunmi O. Afonja, Mark C. Walters
Journal: Blood
Blood (2023) 142 (Supplement 1): 4996.
https://doi.org/10.1182/blood-2023-187397
Published: 2023