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Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140394

Published: 2020

Journal Articles

Imaging Mass Cytometry Reveals the Spatial Architecture of Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemias

Karolyn A. Oetjen, MDPhD, Diane E. Bender, PhD, Marianna B. Ruzinova, MDPhD, Daniel A.C. Fisher, PhD, Stephen T. Oh, MD, Daniel C. Link, MD

Blood (2020) 136 (Supplement 1): 44–45.

https://doi.org/10.1182/blood-2020-142238

Published: 2020

Journal Articles

Evidence of Synergistic Effect of Idasanutlin and Navitoclax Using T-Cell Acute Lymphoblastic Leukemia Patient-Derived Xenografts

Kimberly B. Johansson, Megan Gauthier, MD, Feng Gao, MD PhD MPH, Daniel C. Link, MD

Blood (2020) 136 (Supplement 1): 41.

https://doi.org/10.1182/blood-2020-139690

Published: 2020

Journal Articles

Molecular Profiling of Decitabine Response in MDS and AML Patients

Pawan Kumar Upadhyay, PhD, Jeremy Beales, MS, Nakul Kumar Shah, MD, Christopher A Miller, PhD, Allegra A Petti, PhD, Daniel C. Link, MD, Timothy J Ley, MD, John Welch, MDPhD

Blood (2020) 136 (Supplement 1): 40.

https://doi.org/10.1182/blood-2020-141292

Published: 2020

Journal Articles

TGF-β Signaling Contributes to the Clonal Dominance of Jak2 V617F Hematopoietic Stem/Progenitor Cells

Juo-Chin Yao, Daniel C. Link, MD

Blood (2020) 136 (Supplement 1): 11.

https://doi.org/10.1182/blood-2020-139638

Published: 2020

Journal Articles

Combined Inhibition of CXCR4 Signaling and System x c - Transporter Activity Induces Synthetic Lethality in T-ALL Cells By Suppressing Gsh and Inducing Ferroptosis

Jun Xia, PhD, Stephanie Sun, Matthew RM Jotte, Geoffrey L Uy, MD, Ella Sorani, PhD, Abi Vainstein, Liron Shemesh Davish, Katherine E Caldwell, William G Hawkins, Daniel C. Link, MD

Blood (2020) 136 (Supplement 1): 37.

https://doi.org/10.1182/blood-2020-142735

Published: 2020

Journal Articles

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Salil Uttarwar, Eric J. Duncavage, MD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 470.

https://doi.org/10.1182/blood-2019-128943

Published: 2019

Journal Articles

Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia

Julia T Warren, MD PhD, Peeradol Wattanasirakul, David H Spencer, MD, Adam Locke, PhD, Vahagn Makaryan, MD, Audrey Anna Bolyard, RN, BS, Karl Welte, Julia Skokowa, MD PhD, David C. Dale, MD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 433.

https://doi.org/10.1182/blood-2019-129635

Published: 2019

Journal Articles

Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions

Joseph R. Krambs, BS, Grazia Abou Ezzi, PhD, Juo-Chin Yao, Justin T. Li, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 1209.

https://doi.org/10.1182/blood-2019-128693

Published: 2019

Journal Articles

Interrogating the Spatial Architecture of Human Bone Marrow Via Imaging Mass Cytometry

Karolyn A. Oetjen, MD, Diane E. Bender, PhD, Marianna B. Ruzinova, MD PhD, Stephen T. Oh, MD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 3728.

https://doi.org/10.1182/blood-2019-127460

Published: 2019

Journal Articles

CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma

Geoffrey L. Uy, MD, Tapan M. Kadia, MD, Wendy Stock, MD, Jonathan E Brammer, MD, Osnat Bohana-Kashtan, PhD, Abi Vainstein, Ella Sorani, PhD, Hemda Chen, PharmD, John F. DiPersio, MD PhD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 2630.

https://doi.org/10.1182/blood-2019-127121

Published: 2019

Journal Articles

CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death

Jun Xia, PhD, Stephanie Sun, Matthew RM Jotte, Geoffrey L. Uy, MD, Osnat Bohana-Kashtan, PhD, Ella Sorani, PhD, Abi Vainstein, Amnon Peled, PhD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 2745.

https://doi.org/10.1182/blood-2019-128881

Published: 2019

Journal Articles

Severe Chronic Neutropenia in the Large Granular Lymphocyte Syndrome: Outcomes in Response to Granulocyte Colony Stimulating Factor (G-CSF) and Immunosuppressive Therapies

David C. Dale, MD, James A. Shannon, IV, Audrey Anna Bolyard, RN, BS, Jim Connelly, MD, Daniel C. Link, MD, Mary Ann Bonilla, MD, Peter E. Newburger, MD

Blood (2019) 134 (Supplement_1): 3589.

https://doi.org/10.1182/blood-2019-126181

Published: 2019

Journal Articles

Myelodysplasia, Leukemia, Lymphoid Malignancies, and Other Cancers in Patients with Severe Chronic Neutropenia

David C Dale, MD, Audrey Anna Bolyard, RN, BS, Blanche P. Alter, MD MPH, Mary Ann Bonilla, MD, James Connelly, MD, Daniel C. Link, MD, Peter E. Newburger, MD, Philip S. Rosenberg, PhD, Akiko Shimamura, MD PhD, Kelly J. Walkovich, MD

Blood (2018) 132 (Supplement 1): 16.

https://doi.org/10.1182/blood-2018-99-112694

Published: 2018

Journal Articles

TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches

Grazia Abou Ezzi, PhD, Teerawit Supakorndej, BS, Jingzhu Zhang, BS, Joseph R. Krambs, BS, Hamza Celik, PhD, Daniel C. Link, MD

Blood (2018) 132 (Supplement 1): 3847.

https://doi.org/10.1182/blood-2018-99-117396

Published: 2018

Journal Articles

The CXCR4 Antagonist, BL8040, Is Highly Active Against Human T-ALL in Preclinical Models

Jun Xia, PhD, Matthew RM Jotte, Stephanie Sun, Geoffrey L. Uy, MD, Abi Vainstein, Ella Sorani, PhD, Osnat Bohana-Kashtan, PhD, Stephen Shaw, PhD, Daniel C. Link, MD

Blood (2018) 132 (Supplement 1): 2700.

https://doi.org/10.1182/blood-2018-99-117213

Published: 2018

Journal Articles

Extended Genetic Testing in Severe Congenital Neutropenia May Identify Mutations That Inform Therapy

Daniel C. Link, MD, Vahagn Makaryan, MD, David H Spencer, MDPhD, Jun Xia, PhD, Audrey Anna Bolyard, RN, BS, David C Dale, MD

Blood (2018) 132 (Supplement 1): 2401.

https://doi.org/10.1182/blood-2018-99-116712

Published: 2018

Journal Articles

TGF-Beta Signaling in Mesenchymal Stromal Cells Contributes to Myelofibrosis but Not Hematopoietic Phenotypes in Myeloproliferative Neoplasms

Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Eric J. Duncavage, MD, Daniel C. Link, MD

Blood (2018) 132 (Supplement 1): 3053.

https://doi.org/10.1182/blood-2018-99-113745

Published: 2018

Journal Articles

Understanding the Role of CSF3R and Runx1 Runt Homology Domain Missense Mutations in Leukemic Transformation of Hematopoietic Stem Cells

Malte U Ritter, Olga Klimenkova, Maksim Klimiankou, Amy E Schmidt, MDPhD, Carol Stocking, PhD, Lothar Kanz, Cornelia Zeidler, Daniel C. Link, MD, Karl Welte, Julia Skokowa, MDPhD

Blood (2018) 132 (Supplement 1): 1101.

https://doi.org/10.1182/blood-2018-99-118644

Published: 2018

Journal Articles

A Study of Tbo-Filgrastim (Granix) to Disrupt the Bone Marrow Microenvironment in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation

Meagan Jacoby, MD, Reetom Bera, Theresa Fletcher, Mark A. Fiala, BS, Kathryn Trinkaus, PhD, John F. DiPersio, MD PhD, Keith E. Stockerl-Goldstein, MD, Mark A. Schroeder, MD, Daniel C. Link, MD, Ravi Vij, MBBS

Blood (2018) 132 (Supplement 1): 2146.

https://doi.org/10.1182/blood-2018-99-115603

Published: 2018

NARROW

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Imaging Mass Cytometry Reveals the Spatial Architecture of Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemias

Evidence of Synergistic Effect of Idasanutlin and Navitoclax Using T-Cell Acute Lymphoblastic Leukemia Patient-Derived Xenografts

Molecular Profiling of Decitabine Response in MDS and AML Patients

TGF-β Signaling Contributes to the Clonal Dominance of Jak2 V617F Hematopoietic Stem/Progenitor Cells

Combined Inhibition of CXCR4 Signaling and System x c - Transporter Activity Induces Synthetic Lethality in T-ALL Cells By Suppressing Gsh and Inducing Ferroptosis

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia

Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions

Interrogating the Spatial Architecture of Human Bone Marrow Via Imaging Mass Cytometry

CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma

CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death

Severe Chronic Neutropenia in the Large Granular Lymphocyte Syndrome: Outcomes in Response to Granulocyte Colony Stimulating Factor (G-CSF) and Immunosuppressive Therapies

Myelodysplasia, Leukemia, Lymphoid Malignancies, and Other Cancers in Patients with Severe Chronic Neutropenia

TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches

The CXCR4 Antagonist, BL8040, Is Highly Active Against Human T-ALL in Preclinical Models

Extended Genetic Testing in Severe Congenital Neutropenia May Identify Mutations That Inform Therapy

TGF-Beta Signaling in Mesenchymal Stromal Cells Contributes to Myelofibrosis but Not Hematopoietic Phenotypes in Myeloproliferative Neoplasms

Understanding the Role of CSF3R and Runx1 Runt Homology Domain Missense Mutations in Leukemic Transformation of Hematopoietic Stem Cells

A Study of Tbo-Filgrastim (Granix) to Disrupt the Bone Marrow Microenvironment in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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