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Journal Articles

EBV Microrna Mir-BHRF1-2 Targets PRDM1/Blimp1 : Potential Role in EBV Lymphomagenesis

Jiao Ma, PhD, Kui Nie, PhD, David Redmond, Yifang Liu, MD, Daniel M Knowles, MD, Wayne Tam, MD PhD

Blood (2014) 124 (21): 3547.

https://doi.org/10.1182/blood.V124.21.3547.3547

Published: 2014

Journal Articles

Inactivation Of BANK1 By a Novel IGH -Associated Translocation and 5’ Hypermethylation In B-Cell Lymphomas

Kui Nie, PhD, Taotao Zhang, MD, PhD, Jiong Yan, MD, PhD, Leonardo Boiocchi, MD, Shuhua Cheng, PhD, Susan Mathew, PhD, Yifang Liu, MD, Amy Chadburn, M.D., Attilio Orazi, MD, Daniel M Knowles, MD, Yen-Chun Liu, MD, PHD, Wayne Tam, MD, PhD

Blood (2013) 122 (21): 2497.

https://doi.org/10.1182/blood.V122.21.2497.2497

Published: 2013

Journal Articles

Promoter and Exon 1 Hypermethylation of the Tumor Suppressor Gene PRDM1/Blimp-1 indicates Its Pathogenetic Role in EBV-Positive Burkitt Lymphoma,

Kui Nie, PhD, Taotao Zhang, MD, PhD, Carlos E Bacchi, MD, Eduardo Queiroga, MD, Dra. Gabriela Gualco, MD, Jiong Yan, MD, PhD, Yifang Liu, MD, Sharon Barouk, Attilio Orazi, MD, Daniel M Knowles, MD, Wayne Tam, MD, PhD

Blood (2011) 118 (21): 3471.

https://doi.org/10.1182/blood.V118.21.3471.3471

Published: 2011

Journal Articles

Mutation Burden in CDKN2C, CDK1 and E2F2 Is Associated with Differential Response to Targeting CDK4/CDK6 in Combination with Bortezomib in Mantle Cell Lymphoma,

Christopher E. Mason, PhD, Maurizio Di Liberto, Ph.D., Xiangao Huang, PhD, David Chiron, PhD, Jamieson Bretz, Ph.D., Ramsey Abdallah, B.S., Scott A Ely, M.D., Daniel M Knowles, MD, Peter Martin, MD, John P. Leonard, MD, Selina Chen-Kiang, PhD

Blood (2011) 118 (21): 3738.

https://doi.org/10.1182/blood.V118.21.3738.3738

Published: 2011

Journal Articles

ZAP-70 Expression Assessed by Immunohistochemistry Correlates with Time to First Treatment in Patients with Chronic Lymphocytic Leukemia.

Peter Martin, Amy Chadburn, MD, Wayne Tam, Lauren Tyrell, Rebecca Elstrom, MD, Jia Ruan, MD, PhD, Morton Coleman, Scott Ely, MD, MPH, Daniel M. Knowles, John P. Leonard, Richard R Furman

Blood (2009) 114 (22): 4686.

https://doi.org/10.1182/blood.V114.22.4686.4686

Published: 2009

Journal Articles

Activity of SYK and PLCγ2 Predict Apoptotic Response of Chronic Lymphocytic Leukemia Cells to SRC Tyrosine Kinase Inhibitor Dasatinib.

Y. Lynn Wang, MD, PhD, Zibo Song, Pin Lu, Richard R Furman, John P. Leonard, MD, Peter Martin, Lauren Tyrell, Francis Y. Lee, Daniel M. Knowles, Morton Coleman

Blood (2009) 114 (22): 1249.

https://doi.org/10.1182/blood.V114.22.1249.1249

Published: 2009

Journal Articles

Targeting Early Events of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: Suppressed Syk and PLCγ2 Activities Predict Apoptotic Response of Leukemic Cells to Dasatinib

Y. Lynn Wang, MD, PhD, Zibo Song, Pin Lu, John P. Leonard, Morton Coleman, Peter Martin, Chaowei Wu, Francis Y. Lee, Daniel M. Knowles, Richard Furman

Blood (2008) 112 (11): 5023.

https://doi.org/10.1182/blood.V112.11.5023.5023

Published: 2008

Journal Articles

Long-Distance Tunneling Nanotubules Shuttle Viral Immunoglobulin Class Switch-Suppressing Factors from HIV-Infected Macrophages to B Cells.

Weifeng Xu, PhD, Paul A. Santini, Meimei Shan, PhD, Kang Chen, Susan C. Ball, MD, April Chiu, MD, Lawrence A. Kingsley, PhD, Charles R. Rinaldo, PhD, Amy Chadburn, MD, Daniel M. Knowles, MD, Bing He, Andrea Cerutti, MD

Blood (2007) 110 (11): 2278.

https://doi.org/10.1182/blood.V110.11.2278.2278

Published: 2007

Journal Articles

MicroRNA-Mediated Down-Regulation of the Tumor Suppressor Gene PRDM1 /Blimp-1 in Diffuse Large B-Cell Lymphomas.

Kui Nie, PhD, Hatim Allawi, Ph.D., Victor Lyamichev, Ph.D., Mario F. Gomez, B.S., Yifang Liu, M.D., Amy Chadburn, M.D., Daniel M. Knowles, M.D., Wayne Tam, M.D., Ph.D.

Blood (2007) 110 (11): 3187.

https://doi.org/10.1182/blood.V110.11.3187.3187

Published: 2007

Journal Articles

Quantitative Assessment of DNA Editing Enzymes in B-Cell Lymphomas.

Y. Lynn Wang, MD PhD, Pin Lu, Ph.D., Sun M. Chung, MD, Andrea Cerutti, M.D. Ph.D., Zibo Song, MD, Amy Chadburn, MD, Wayne Tam, M.D. PhD, Ethel Cesarman, M.D. Ph.D., Daniel M. Knowles, M.D.

Blood (2007) 110 (11): 4687.

https://doi.org/10.1182/blood.V110.11.4687.4687

Published: 2007

Journal Articles

Malignant B Cells from Hairy Cell Leukemia Express an Innate Phenotype and Undergo IgD Class Switching in Response to Innate Environmental Factors, Including BAFF and APRIL.

April Chiu, MD, Kang Chen, Bing He, Stacey Dillon, PhD, Amy Chadburn, MD, Daniel M. Knowles, MD, Weifeng Xu, PhD, Andrea Cerutti, MD

Blood (2007) 110 (11): 4707.

https://doi.org/10.1182/blood.V110.11.4707.4707

Published: 2007

Journal Articles

Splenic Sinusoids Stimulate the Survival and Proliferation of Hairy Cell Leukemia B Cells through BAFF, APRIL and Heparan-Sulphate Proteoglycans.

April Chiu, MD, Weifeng Xu, PhD, Bing He, Paul Santini, Stacey R. Dillon, PhD, Amy Chadburn, MD, Daniel M. Knowles, MD, Andrea Cerutti, MD

Blood (2006) 108 (11): 4959.

https://doi.org/10.1182/blood.V108.11.4959.4959

Published: 2006

Journal Articles

Mucosal Epithelial Cells Initiate Frontline Immunoglobulin Class Switching through an SLPI-Regulated Pathway.

Andrea Cerutti, MD, Bing He, April Chiu, Meimei Shan, PhD, Paul Santini, Amy Chadburn, MD, Daniel M. Knowles, MD, Weifeng Xu, PhD

Blood (2006) 108 (11): 3898.

https://doi.org/10.1182/blood.V108.11.3898.3898

Published: 2006

Journal Articles

MicroRNA-Mediated Translation Repression of PRDM1 in Hodgkin/Reed-Sternberg Cells - A Potential Pathogenetic Lesion in Hodgkin Lymphoma.

Kui Nie, PhD, Mario F. Gomez, M.S., Pablo Landgraf, M.D., Ph.D., Jose-Francisco Garcia, Ph.D., Yifang Liu, M.D., Leonard H.C. Tan, M.B.,B.S, Amy Chadburn, M.D., Thomas Tuschl, Ph.D., Daniel M. Knowles, M.D., Wayne Tam, MD, PhD

Blood (2006) 108 (11): 614.

https://doi.org/10.1182/blood.V108.11.614.614

Published: 2006

Journal Articles

Neither Germinal Center (GC) vs Non-Germinal Center (Non-GC) Phenotype nor FOXP1 Expression Correlate with Outcome in AIDS-Associated Diffuse Large B-Cell Lymphoma (DLBCL): Study of Patients from AIDS Malignancies Consortium Trials 010 and 034.

Amy Chadburn, MD, Xia Chen, MD PhD, April Chiu, MD, Elizabeth Hyjek, MD PhD, Wayne Tam, MD PhD, Lawrence Kaplan, MD, David T. Scadden, MD, Daniel M. Knowles, MD, Ethel Cesarman, MD PhD

Blood (2006) 108 (11): 2023.

https://doi.org/10.1182/blood.V108.11.2023.2023

Published: 2006

Journal Articles

Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL

April Chiu, Weifeng Xu, Bing He, Stacey R. Dillon, Jane A. Gross, Eric Sievers, Xugang Qiao, Paul Santini, Elizabeth Hyjek, Joong-won Lee, Ethel Cesarman, Amy Chadburn, Daniel M. Knowles, Andrea Cerutti

Blood (2006) 109 (2): 729–739.

https://doi.org/10.1182/blood-2006-04-015958

Published: 2006

Journal Articles

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

Wayne Tam, Mario Gomez, Amy Chadburn, Joong W. Lee, Wing C. Chan, Daniel M. Knowles

Blood (2006) 107 (10): 4090–4100.

https://doi.org/10.1182/blood-2005-09-3778

Published: 2006

Journal Articles

Mutually Exclusive Cdk4-Cyclin D1 and Cdk6-Cyclin D2 Pairing Inactivates Rb and Promotes Cell Cycle Dysregulation in Multiple Myeloma.

Scott Ely, MD, MPH, Maurizio Di Liberto, PhD, Ruben Niesvizky, MD, Eunice Hatada, PhD, Hearn Cho, MD, PhD, Daniel M. Knowles, MD, Joseph Lane, MD, Selina Chen-Kiang, PhD

Blood (2005) 106 (11): 501.

https://doi.org/10.1182/blood.V106.11.501.501

Published: 2005

Journal Articles

Lack of PRDM1α Expression in Hodgkin/Reed-Sternberg Cells Is Likely Mediated by a Translational or Post-Translational Mechanism.

Wayne Tam, MD, PhD, Leonard Tan, M.B., BS, Mario Gomez, BS, Shaoan Fan, PhD, Yifang Liu, MD, Kenneth Wright, PhD, Amy Chadburn, MD, Daniel M. Knowles, MD

Blood (2005) 106 (11): 4367.

https://doi.org/10.1182/blood.V106.11.4367.4367

Published: 2005

Journal Articles

HIV-1 Nef Suppresses T Cell-Dependent Immunoglobulin Class Switching by Inducing Inhibitors of CD40 and IL-4 Receptor Signaling in Bystander B Cells.

Andrea Cerutti, MD, Bing He, April Chiu, MD, Daniel M. Knowles, MD, Amy Chadburn, MD, Xugang Qiao, MD

Blood (2005) 106 (11): 325.

https://doi.org/10.1182/blood.V106.11.325.325

Published: 2005

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EBV Microrna Mir-BHRF1-2 Targets PRDM1/Blimp1 : Potential Role in EBV Lymphomagenesis

Inactivation Of BANK1 By a Novel IGH -Associated Translocation and 5’ Hypermethylation In B-Cell Lymphomas

Promoter and Exon 1 Hypermethylation of the Tumor Suppressor Gene PRDM1/Blimp-1 indicates Its Pathogenetic Role in EBV-Positive Burkitt Lymphoma,

Mutation Burden in CDKN2C, CDK1 and E2F2 Is Associated with Differential Response to Targeting CDK4/CDK6 in Combination with Bortezomib in Mantle Cell Lymphoma,

ZAP-70 Expression Assessed by Immunohistochemistry Correlates with Time to First Treatment in Patients with Chronic Lymphocytic Leukemia.

Activity of SYK and PLCγ2 Predict Apoptotic Response of Chronic Lymphocytic Leukemia Cells to SRC Tyrosine Kinase Inhibitor Dasatinib.

Targeting Early Events of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: Suppressed Syk and PLCγ2 Activities Predict Apoptotic Response of Leukemic Cells to Dasatinib

Long-Distance Tunneling Nanotubules Shuttle Viral Immunoglobulin Class Switch-Suppressing Factors from HIV-Infected Macrophages to B Cells.

MicroRNA-Mediated Down-Regulation of the Tumor Suppressor Gene PRDM1 /Blimp-1 in Diffuse Large B-Cell Lymphomas.

Quantitative Assessment of DNA Editing Enzymes in B-Cell Lymphomas.

Malignant B Cells from Hairy Cell Leukemia Express an Innate Phenotype and Undergo IgD Class Switching in Response to Innate Environmental Factors, Including BAFF and APRIL.

Splenic Sinusoids Stimulate the Survival and Proliferation of Hairy Cell Leukemia B Cells through BAFF, APRIL and Heparan-Sulphate Proteoglycans.

Mucosal Epithelial Cells Initiate Frontline Immunoglobulin Class Switching through an SLPI-Regulated Pathway.

MicroRNA-Mediated Translation Repression of PRDM1 in Hodgkin/Reed-Sternberg Cells - A Potential Pathogenetic Lesion in Hodgkin Lymphoma.

Neither Germinal Center (GC) vs Non-Germinal Center (Non-GC) Phenotype nor FOXP1 Expression Correlate with Outcome in AIDS-Associated Diffuse Large B-Cell Lymphoma (DLBCL): Study of Patients from AIDS Malignancies Consortium Trials 010 and 034.

Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

Mutually Exclusive Cdk4-Cyclin D1 and Cdk6-Cyclin D2 Pairing Inactivates Rb and Promotes Cell Cycle Dysregulation in Multiple Myeloma.

Lack of PRDM1α Expression in Hodgkin/Reed-Sternberg Cells Is Likely Mediated by a Translational or Post-Translational Mechanism.

HIV-1 Nef Suppresses T Cell-Dependent Immunoglobulin Class Switching by Inducing Inhibitors of CD40 and IL-4 Receptor Signaling in Bystander B Cells.

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