Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 23

Sort by

Sort Order Select

Journal Articles

Live Lymphoma and CLL Cells inside the Bone Marrow Fibroblasts: Implication in Residual Disease Persistence

Y. Lynn Wang, Carrie Frazen, Andrey Efimov, Priyal Patel, Pin Lu, Shuo Ma, Katherine Amira Carrol, Edna Cukierman, Marcus R. Messmer, Janusz Franco-Barraza, Juehua Gao, Aldana Vistarop

Blood (2023) 142 (Supplement 1): 6506.

https://doi.org/10.1182/blood-2023-179994

Published: 2023

Journal Articles

SHP1 Loss Augments DLBCL Cellular Response to Ibrutinib: A Candidate Predictive Biomarker

Y. Lynn Wang, Ji Ma, Vinay Mallikarjuna, Pin Lu, Shengchun Wang, Sahar Poureghbali, Mariusz A Wasik, Reza Nejati, Wenjun Wu

Blood (2021) 138 (Supplement 1): 3490.

https://doi.org/10.1182/blood-2021-146086

Published: 2021

Journal Articles

Inhibition of B-Cell Receptor Signaling Disrupts Cell Adhesion in Mantle Cell Lymphoma Via RAC2

Weige Wang, MD, Franzen Carrie, Hui Guo, PhD, Jimmy Lee, MD, Yan Li, Madina Sukhanova, PhD, Dong Sheng, MD, Girish Venkataraman, MD MBBS, Ming Mei, Pin Lu, PhD, Anhui Gao, Chunmei Xia, Li Jia, Liang Zhang, MD PhD, Michael Wang, MD, Jorge Andrade, Zhou Xiaoyan, Y. Lynn Lynn Wang, MDPhD

Blood (2018) 132 (Supplement 1): 1369.

https://doi.org/10.1182/blood-2018-99-118598

Published: 2018

Journal Articles

XPO1 Inhibitor Selinexor Overcomes Ibrutinib Resistance in Mantle Cell Lymphoma Via Nuclear Retention of IκB

Y. Lynn Wang, MD PhD, Mei Ming, PhD, Bingqing Xie, Madina Sukhanova, Weige Wang, MD, Sabah Kadri, PhD, Shruti Sharma, Jimmy Lee, Sharon Shacham, PhD MBA, Yosef Landesman, PhD, Natalia Maltsev, Pin Lu, PhD

Blood (2017) 130 (Supplement 1): 3837.

https://doi.org/10.1182/blood.V130.Suppl_1.3837.3837

Published: 2017

Journal Articles

Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B Cell Malignancies: Results from a Phase I Dose Escalation Study

Gregory P. Coffey, PhD, Jiajia Feng, MD, Andreas Betz, PhD, Anjali Pandey, PhD, Matt Birrell, B.S., Janet M. Leeds, PhD, Kenneth Der, PhD, Sabah Kadri, PhD, Pin Lu, PhD, Jeremy Segal, PhD, Lynn Wang, MD PhD, Glenn Michelson, MD, John T Curnutte, MD PhD, Pamela B. Conley, PhD

Blood (2017) 130 (Supplement 1): 2782.

https://doi.org/10.1182/blood.V130.Suppl_1.2782.2782

Published: 2017

Journal Articles

RAC2 Links B-Cell Receptor Signaling and Cell Adhesion in Mantle Cell Lymphoma

Weige Wang, Franzen Carrie, Madina Sukhanova, Venkataraman Girish, Ming Mei, Guo Ailin, Pin Lu, PhD, Dong Sheng, MD, Gao Anhui, Xia Chunmei, Li Jia, Zhou Xiaoyan, Y Lynn Wang

Blood (2017) 130 (Supplement 1): 2752.

https://doi.org/10.1182/blood.V130.Suppl_1.2752.2752

Published: 2017

Journal Articles

Clonal Evolution Pattern of Leukemia Progression and Richter Transformation in Ibrutinib-Relapsed CLL Patients

Blood (2016) 128 (22): 3961.

https://doi.org/10.1182/blood.V128.22.3961.3961

Published: 2016

Journal Articles

A 6-Lncrna Scoring System for Prognostication of Adult Myelodysplastic Syndromes

Chi-Yuan Yao, Ching-Hsuan Chen, Whai-Shuan Huang, Hsin-An Hou, MD PhD, Chien-Chin Lin, Mei-Hsuan Tseng, Chein-Jun Kao, Tzu-Pin Lu, Wen-Chien Chou, MD PhD, Hwei-Fang Tien, MD PhD

Blood (2016) 128 (22): 4344.

https://doi.org/10.1182/blood.V128.22.4344.4344

Published: 2016

Journal Articles

Genetic or CD40L-Mediated Loss of Iκbα Is Associated with Resistance to the Dual SYK/JAK Inhibitor Cerdulatinib in DLBCL Cell Lines

Greg P Coffey, PhD, Jiajia Feng, MD, Sabah Kadri, PhD, Y. Lynn Wang, MD PhD, Pin Lu, PhD, Shruti Sharma, PhD, Jeremy Segal, PhD, Glenn Michelson, MD, Anjali Pandey, PhD, John T. Curnutte, MD PhD, Pamela B. Conley, PhD

Blood (2016) 128 (22): 2768.

https://doi.org/10.1182/blood.V128.22.2768.2768

Published: 2016

Journal Articles

Dual SYK/JAK Inhibition Overcomes Ibrutinib Resistance in Chronic Lymphocytic Leukemia

Yue Lynn Wang, MD PhD, Pin Lu, PhD, Greg P Coffey, PhD, Anjali Pandey, PhD, Ailin Guo, PhD MD

Blood (2016) 128 (22): 5377.

https://doi.org/10.1182/blood.V128.22.5377.5377

Published: 2016

Journal Articles

HSP90 Stabilizes B-Cell Receptor Kinases in a Multi-Client Interactome: PU-H71 Induces CLL Apoptosis in a Cytoprotective Microenvironment

Yue Lynn Wang, MD PhD, Pin Lu, PhD, Jimmy Lee, MD, Chao Jie Zhen, BS, Gabriela Chiosis, PhD, Ailin Guo, Ph DMD

Blood (2016) 128 (22): 5105.

https://doi.org/10.1182/blood.V128.22.5105.5105

Published: 2016

Journal Articles

Higher BTK-Dependent Cell Proliferation in Unmutated Chronic Lymphocytic Leukemia Confers Increased Sensitivity to Ibrutinib

Ailin Guo, PhDMD, Pin Lu, PhD, Natalie Galanina, MD, Chadi Nabhan, MD, Sonali M. Smith, MD, Morton Coleman, MD, Yue Lynn Wang, MD PhD

Blood (2015) 126 (23): 5296.

https://doi.org/10.1182/blood.V126.23.5296.5296

Published: 2015

Journal Articles

An Accurate and Sensitive RT-qPCR Method That Reliably Detects BCR-ABL1 Beyond MR4.5

Nadia A. McDonald, B.Sc., MS, Brett E. Close, PhD, Pin Lu, PhD, Jeremy P. Segal, MD PhD, Yue Lynn Wang, MD PhD, Larissa V. Furtado, MD

Blood (2015) 126 (23): 5159.

https://doi.org/10.1182/blood.V126.23.5159.5159

Published: 2015

Journal Articles

An HSP90 Inhibitor, PU-H71, Antagonizes Stroma-Induced Pro-Survival Effects in CLL through Its Inhibition of Multi-Component B-Cell Receptor Signaling Pathway

Ailin Guo, PhDMD, Pin Lu, PhD, Chaojie Zhen, PhD, Gabriela Chiosis, PhD, Yue Lynn Wang, MD PhD

Blood (2015) 126 (23): 5289.

https://doi.org/10.1182/blood.V126.23.5289.5289

Published: 2015

Journal Articles

SYK and STAT3 Are Active in Diffuse Large B-Cell Lymphoma: Activity of Cerdulatinib, a Dual SYK/JAK Inhibitor

Y. Lynn Wang, MD PhD, Jiao Ma, PhD, Wei Xing, PhD, Pin Lu, MD PhD, Karen Dresser, Ailin Guo, PhDMD, Anjali Pandey, PhD, Pamela B. Conley, PhD, Hongbo Yu, MD PhD, Greg Coffey, PhD

Blood (2014) 124 (21): 926.

https://doi.org/10.1182/blood.V124.21.926.926

Published: 2014

Journal Articles

A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL

Richard R. Furman, MD, Shuhua Cheng, PhD, Pin Lu, MD, PhD, Menu Setty, Alexandar Perez, Ailin Guo, MD, PhD, Joelle Racchumi, BS, Jiao Ma, PhD, Morton Coleman, MD, Kabaleeswaran Venkataraman, PhD, Guozhou Xu, PhD, Wei Chen, PhD, Hao Wu, PhD, Betty Y. Chang, PhD, Christina Leslie, PhD, Y. Lynn Wang, MD, PhD

Blood (2013) 122 (21): 4914.

https://doi.org/10.1182/blood.V122.21.4914.4914

Published: 2013

Journal Articles

Dual SYK/JAK Inhibition Has a Broader Anti-Tumor Activity In Both ABC and GCB Types Of Diffuse Large B Cell Lymphoma

Jiao Ma, PhD, Greg Coffey, PhD, Pin Lu, MD, PhD, Shuhua Cheng, PhD, Ailin Guo, MD, PhD, Anjali Pandey, PhD, Y. Lynn Wang, MD, PhD

Blood (2013) 122 (21): 1833.

https://doi.org/10.1182/blood.V122.21.1833.1833

Published: 2013

Journal Articles

Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

Utthara Nayar, Pin Lu, Rebecca L. Goldstein, Jelena Vider, Gianna Ballon, Anna Rodina, Tony Taldone, Hediye Erdjument-Bromage, Max Chomet, Ronald Blasberg, Ari Melnick, Leandro Cerchietti, Gabriela Chiosis, Y. Lynn Wang, Ethel Cesarman

Blood (2013) 122 (16): 2837–2847.

https://doi.org/10.1182/blood-2013-01-479972

Published: 2013

Includes: Supplemental data

Journal Articles

BTK Inhibition Targets in Vivo CLL Proliferation Through Its Effects On B-Cell Receptor Signaling Activity.

Y. Lynn Wang, MD, PhD, Shuhua Cheng, PhD, Jiao Ma, PhD, Ailin Guo, MD, PhD, Pin Lu, MD, PhD, John P. Leonard, MD, Morton Coleman, MD, Momo Liu, BS, Joseph J. Buggy, PhD, Richard R. Furman, MD

Blood (2012) 120 (21): 2903.

https://doi.org/10.1182/blood.V120.21.2903.2903

Published: 2012

Journal Articles

SYK inhibition and response prediction in diffuse large B-cell lymphoma

Shuhua Cheng, Greg Coffey, X. Hannah Zhang, Rita Shaknovich, Zibo Song, Pin Lu, Anjali Pandey, Ari M. Melnick, Uma Sinha, Y. Lynn Wang

Blood (2011) 118 (24): 6342–6352.

https://doi.org/10.1182/blood-2011-02-333773

Published: 2011

Includes: Supplemental data

NARROW

Live Lymphoma and CLL Cells inside the Bone Marrow Fibroblasts: Implication in Residual Disease Persistence

SHP1 Loss Augments DLBCL Cellular Response to Ibrutinib: A Candidate Predictive Biomarker

Inhibition of B-Cell Receptor Signaling Disrupts Cell Adhesion in Mantle Cell Lymphoma Via RAC2

XPO1 Inhibitor Selinexor Overcomes Ibrutinib Resistance in Mantle Cell Lymphoma Via Nuclear Retention of IκB

Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B Cell Malignancies: Results from a Phase I Dose Escalation Study

RAC2 Links B-Cell Receptor Signaling and Cell Adhesion in Mantle Cell Lymphoma

Clonal Evolution Pattern of Leukemia Progression and Richter Transformation in Ibrutinib-Relapsed CLL Patients

A 6-Lncrna Scoring System for Prognostication of Adult Myelodysplastic Syndromes

Genetic or CD40L-Mediated Loss of Iκbα Is Associated with Resistance to the Dual SYK/JAK Inhibitor Cerdulatinib in DLBCL Cell Lines

Dual SYK/JAK Inhibition Overcomes Ibrutinib Resistance in Chronic Lymphocytic Leukemia

HSP90 Stabilizes B-Cell Receptor Kinases in a Multi-Client Interactome: PU-H71 Induces CLL Apoptosis in a Cytoprotective Microenvironment

Higher BTK-Dependent Cell Proliferation in Unmutated Chronic Lymphocytic Leukemia Confers Increased Sensitivity to Ibrutinib

An Accurate and Sensitive RT-qPCR Method That Reliably Detects BCR-ABL1 Beyond MR4.5

An HSP90 Inhibitor, PU-H71, Antagonizes Stroma-Induced Pro-Survival Effects in CLL through Its Inhibition of Multi-Component B-Cell Receptor Signaling Pathway

SYK and STAT3 Are Active in Diffuse Large B-Cell Lymphoma: Activity of Cerdulatinib, a Dual SYK/JAK Inhibitor

A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL

Dual SYK/JAK Inhibition Has a Broader Anti-Tumor Activity In Both ABC and GCB Types Of Diffuse Large B Cell Lymphoma

Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

BTK Inhibition Targets in Vivo CLL Proliferation Through Its Effects On B-Cell Receptor Signaling Activity.

SYK inhibition and response prediction in diffuse large B-cell lymphoma

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only