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David C Taussig
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Journal Articles

Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study

Clinical Trials & Observations
Teena Bhatla, Laura E. Hogan, David T. Teachey, Francisco Bautista, John Moppett, Pablo Velasco Puyó, Concetta Micalizzi, Claudia Rossig, Neerav Shukla, Gil Gilad, Franco Locatelli, André Baruchel, C. Michel Zwaan, Natalie S. Bezler, Alba Rubio-San-Simón, David C. Taussig, Elizabeth A. Raetz, Zhengwei J. Mao, Brent L. Wood, Diana Alvarez Arias, Maria Krevvata, Ivo Nnane, Nibedita Bandyopadhyay, Lorena Lopez Solano, Robyn M. Dennis, Robin Carson, Ajay Vora
Journal: Blood
Blood (2024) 144 (21): 2237–2247.
https://doi.org/10.1182/blood.2024024493
Published: 2024
Includes: Supplemental data
Journal Articles

Olutasidenib (FT-2102) Induces Durable Complete Remissions in Patients with Relapsed/Refractory mIDH1 Acute Myeloid Leukemia. Results from a Planned Interim Analysis of a Phase 2 Pivotal Clinical Trial

Jorge E. Cortes, Pierre Fenaux, Karen Yee, Christian Recher, Andrew H. Wei, Pau Montesinos, David C Taussig, Arnaud Pigneux, Thorsten Braun, Antonio Curti, Carolyn Grove, Brian A. Jonas, Asim Khwaja, Pierre Peterlin, Olga Polyanskaya, Jennifer Sweeney, Julie Brevard, Emma Barrett, Stephane De Botton
Journal: Blood
Blood (2022) 140 (Supplement 1): 6193–6196.
https://doi.org/10.1182/blood-2022-167330
Published: 2022
Journal Articles

Venetoclax-Based Non-Intensive Combinations Successfully Salvage Molecular Relapse of Acute Myeloid Leukemia and Are an Important Bridge to Cellular Therapy in Relapsed/Refractory Disease - Real-World Data from a UK-Wide Programme

Henry Wood, Christianne Bourlon, Austin Kulasekararaj, Albert Borg, Jiri Pavlu, Patrick Elder, David C Taussig, Scott Veitch, Steven Knapper, Jad Othman, Richard Dillon, James Aries, Emily Mitchell, Faisal Basheer, Steven Leak, Vidhya Murthy, Joe W Cross, Priyanka Mehta, Manish Jain, Anjum Khan, Ho Lam, Sarah Leong, Jenny O'Nions, Charles Craddock, Victoria Potter, Mhairi Copland, Pramila Krishnamurthy
Journal: Blood
Blood (2022) 140 (Supplement 1): 9016–9018.
https://doi.org/10.1182/blood-2022-167097
Published: 2022
Journal Articles

Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo

Farideh Miraki-Moud, Essam Ghazaly, Linda Ariza-McNaughton, Katharine A. Hodby, Andrew Clear, Fernando Anjos-Afonso, Konstantinos Liapis, Marianne Grantham, Fareeda Sohrabi, Jamie Cavenagh, John S. Bomalaski, John G. Gribben, Peter W. Szlosarek, Dominique Bonnet, David C. Taussig
Journal: Blood
Blood (2015) 125 (26): 4060–4068.
https://doi.org/10.1182/blood-2014-10-608133
Published: 2015
Includes: Supplemental data
Journal Articles

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Essam Ghazaly, MD PhD, Paul Smith, PhD, Chathunissa Gnanaranjan, MSc, Bryan D Young, BSc, PhD, Simon Joel, PhD, John G. Gribben, MD DSc, David C Taussig, PhD MRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 5324.
https://doi.org/10.1182/blood.V124.21.5324.5324
Published: 2014
Journal Articles

Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo

Farideh Miraki-Moud, PhD, Linda Ariza-McNaughton, MSc, Essam A Ghazaly, MD, Katharine A Hodby, Phuong Luong, Andrew Clear, PhD, Fareeda Sohrabi, John Bomalaski, John Gribben, MD, DSc, Dominique Bonnet, PhD, Peter Szlosarek, David C Taussig, PhD, MRCP, FRCPath
Journal: Blood
Blood (2013) 122 (21): 1458.
https://doi.org/10.1182/blood.V122.21.1458.1458
Published: 2013
Journal Articles

Anergic Response to B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia: The Differing Roles of IgD and IgM in the Microenvironment and Peripheral Blood.

Tom Butler, MD, Alexander Montoya, Andrew James Clear, BSc, Rita Coutinho, MD, David C Taussig, PhD, MRCP, FRCPath, Pedro Cutillas, PhD, John G Gribben
Journal: Blood
Blood (2012) 120 (21): 2889.
https://doi.org/10.1182/blood.V120.21.2889.2889
Published: 2012
Journal Articles

Human Primary Mantle Cell Lymphoma Can Be Established in NOD/SCID/IL2Rγ-Null Mice

Sunil Iyengar, MD, Linda Ariza-McNaughton, MSc, Andrew James Clear, BSc, Amy Roe, Debra Lillington, PhD, David C Taussig, PhD, MRCP, FRCPath, John G Gribben, Simon Joel, Dominique Bonnet, PhD
Journal: Blood
Blood (2012) 120 (21): 1565.
https://doi.org/10.1182/blood.V120.21.1565.1565
Published: 2012
Journal Articles

Continuous CD4+ T Cell Lines Derived From the Classical Hodgkin Lymphoma Microenvironment: A Challenge to the Assumption of Anergy,

Paul Greaves, Sameena Iqbal, David C Taussig, PhD, MRCP, FRCPath, John G. Gribben, MD, DSc
Journal: Blood
Blood (2011) 118 (21): 3645.
https://doi.org/10.1182/blood.V118.21.3645.3645
Published: 2011
Journal Articles

A Phase II Trial of Sequential Treatment with Cytoreductive Therapy and Reduced Intensity Conditioning Allogeneic Stem Cell Transplantation for Relapsed/Refractory Acute Myeloid Leukaemia, High-Risk MDS and Other High Risk Myeoid Malignancies: An Interim Report.

Dimitris A Tsitsikas, Dana Warcel-Sibony, Heather E. Oakervee, MBBS, BSc, MD, MRCP, FRCPath, Samir G Agrawal, Matthew Smith, David C Taussig, PhD, MRCP, FRCPath, Johannes de Vos, Elaine Stewart, Hannah Nicholas, John G. Gribben, MD, DSc, James D Cavenagh
Journal: Blood
Blood (2010) 116 (21): 3480.
https://doi.org/10.1182/blood.V116.21.3480.3480
Published: 2010
Journal Articles

Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34 − fraction

David C. Taussig, Jacques Vargaftig, Farideh Miraki-Moud, Emmanuel Griessinger, Kirsty Sharrock, Tina Luke, Debra Lillington, Heather Oakervee, Jamie Cavenagh, Samir G. Agrawal, T. Andrew Lister, John G. Gribben, Dominique Bonnet
Journal: Blood
Blood (2010) 115 (10): 1976–1984.
https://doi.org/10.1182/blood-2009-02-206565
Published: 2010
Includes: Supplemental data
Journal Articles

Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts

Rifca Le Dieu, David C. Taussig, Alan G. Ramsay, Richard Mitter, Faridah Miraki-Moud, Rewas Fatah, Abigail M. Lee, T. Andrew Lister, John G. Gribben
Journal: Blood
Blood (2009) 114 (18): 3909–3916.
https://doi.org/10.1182/blood-2009-02-206946
Published: 2009
Includes: Supplemental data
Journal Articles

Anti-CD38 antibody–mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

David C. Taussig, Farideh Miraki-Moud, Fernando Anjos-Afonso, Daniel J. Pearce, Kirsty Allen, Christopher Ridler, Debra Lillington, Heather Oakervee, Jamie Cavenagh, Samir G. Agrawal, T. Andrew Lister, John G. Gribben, Dominique Bonnet
Journal: Blood
Blood (2008) 112 (3): 568–575.
https://doi.org/10.1182/blood-2007-10-118331
Published: 2008
Includes: Supplemental data
Journal Articles

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

David C. Taussig, Daniel J. Pearce, Catherine Simpson, Ama Z. Rohatiner, T. Andrew Lister, Gavin Kelly, Jennifer L. Luongo, Gwenn-aël H. Danet-Desnoyers, Dominique Bonnet
Journal: Blood
Blood (2005) 106 (13): 4086–4092.
https://doi.org/10.1182/blood-2005-03-1072
Published: 2005
Includes: Supplemental data