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David C. Fajgenbaum
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Journal Articles

Exploratory Analyses of Lymph Node Tissue, Serum, and Peripheral Blood Mononuclear Cells Do Not Reveal Pathogen Signatures in Idiopathic Multicentric Castleman Disease

Ira Miller, Daniel Jose Arenas, Melanie Mumau, Michael V. Gonzalez, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 4402.
https://doi.org/10.1182/blood-2023-188991
Published: 2023
Journal Articles

Clinical Characteristics and Treatment Outcomes of Idiopathic Multicentric Castleman Disease: Data from a Pediatric Cohort

Saishravan Shyamsundar, Mateo Sarmiento Bustamante, Sheila K. Pierson, Joshua D. Brandstadter, Frits van Rhee, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 4415.
https://doi.org/10.1182/blood-2023-183039
Published: 2023
Journal Articles

A Translational Approach to Identifying and Targeting TNF Signaling in Idiopathic Multicentric Castleman Disease

Melanie Mumau, Abiola Irvine, Chunyu Ma, Sheila K. Pierson, Brent Shaw, Michael V. Gonzalez, Daniel Korn, Tracey Sikora, Grant Mitchell, David Koslicki, Luke Y. C. Chen, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2023-188076
Published: 2023
Journal Articles

Identification of Autoantibodies Associated with Connective Tissue Disorders in Idiopathic Multicentric Castleman Disease

Allan Feng, Michael V. Gonzalez, Melanie Mumau, Saishravan Shyamsundar, Paul J. Utz, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 1993.
https://doi.org/10.1182/blood-2023-189788
Published: 2023
Journal Articles

The Role of CABIN1 in the Pathogenesis of Idiopathic Multicentric Castleman Disease

Dorottya Laczko, David C. Fajgenbaum, Taku Kambayashi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3920.
https://doi.org/10.1182/blood-2023-182283
Published: 2023
Journal Articles

Clinical Characteristics, Treatment Trends, and Outcomes of Patients with HHV-8-Negative/Idiopathic Multicentric Castleman Disease Treated with Siltuximab in a Machine Learning-Selected Real-World Cohort

Aaron B Cohen, Melissa Estevez, Jonathan G Kelly, James N Gippetti, Erin L Fidyk, Joshua D. Brandstadter, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 907.
https://doi.org/10.1182/blood-2023-174924
Published: 2023
Journal Articles

Immune Checkpoint Inhibitors and the Risk of Cardiovascular Adverse Events: A Pooled Clinical Trial Database Analysis

Kayleen Ports, Rahul Jain, Sheila Diamond, Jacob Aptekar, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 6933.
https://doi.org/10.1182/blood-2023-181968
Published: 2023
Journal Articles

Deriving Predictive Features of Severe CRS from Pre-Infusion Clinical Data in CAR T-Cell Therapies

Vibhu Agarwal, Jacob Aptekar, David C Fajgenbaum, Penelope Lafeuille
Journal: Blood
Blood (2022) 140 (Supplement 1): 7838–7839.
https://doi.org/10.1182/blood-2022-169287
Published: 2022
Journal Articles

Serum Proteomics Identifies Interferon Gamma Signaling in Idiopathic Multicentric Castleman Disease

Melanie Mumau, Sheila K Pierson, Michael Gonzalez, Scott Canna, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 5500–5501.
https://doi.org/10.1182/blood-2022-167829
Published: 2022
Journal Articles

A Novel Cryopreservation and Biobanking Strategy to Study Lymphoid Tissue Stromal Cells in Lymphoproliferative Disorders

Joshua D Brandstadter, Angelina De Martin, Mechthild Lϋetge, Antonio Ferreira, Brian T. Gaudette, Michael Gonzalez, Yves Stanossek, Edward Camiolo, Gerald Wertheim, David Allman, David C Fajgenbaum, Jon C. Aster, Burkhard Ludewig, Ivan Maillard
Journal: Blood
Blood (2022) 140 (Supplement 1): 3562–3563.
https://doi.org/10.1182/blood-2022-159835
Published: 2022
Journal Articles

Increased Comorbidities and Hospitalizations Associated with Idiopathic Multicentric Castleman Disease

Mateo Sarmiento Bustamante, Sheila K Pierson, Yue Ren, Daisy Alapat, Adam Bagg, Joshua D Brandstadter, Mary Jo Lechowicz, Hongzhe Lee, Gordan Srkalovic, Megan S. Lim, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 6520–6521.
https://doi.org/10.1182/blood-2022-170102
Published: 2022
Journal Articles

Longitudinal, Real-World Data Reveal Treatment Effectiveness in Idiopathic Multicentric Castleman Disease and Support Current Treatment Guidelines

Sheila K Pierson, Mateo Sarmiento Bustamante, Joshua D Brandstadter, Daisy Alapat, Adam Bagg, Mary Jo Lechowicz, Gordan Srkalovic, Megan S. Lim, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2022) 140 (Supplement 1): 9378–9379.
https://doi.org/10.1182/blood-2022-170360
Published: 2022
Journal Articles

Insights into the Natural History and Treatment Outcomes of Hemophagocytic Lymphohistiocytosis (HLH): The into-HLH Registry

Adi Zoref-Lorenz, David C. Fajgenbaum, Sheila K. Pierson, Abiola Oladapo, John Yee, Nitya Gulati, Carl E. Allen, Michael B. Jordan
Journal: Blood
Blood (2022) 140 (Supplement 1): 11170–11171.
https://doi.org/10.1182/blood-2022-170288
Published: 2022
Journal Articles

Increased mTORC2 Pathway Activation in Lymph Nodes of Imcd-Tafro

Alexis D Phillips, Joseph K Kakkis, Patricia Y Tsao, Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 4316.
https://doi.org/10.1182/blood-2021-146821
Published: 2021
Journal Articles

Safety and Tolerability of Sars-Cov-2 Vaccination and Natural History of Infection Among Patients with Castleman Disease

Sheila K Pierson, Russell Perkins, Frits van Rhee, Corey Casper, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2696.
https://doi.org/10.1182/blood-2021-153797
Published: 2021
Journal Articles

Characterizing Serum Cytokine Levels in Idiopathic Multicentric Castleman Disease Reveals Increased Chemokines and a Potential Signature Compared to Related Diseases

Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2693.
https://doi.org/10.1182/blood-2021-153893
Published: 2021
Journal Articles

Ongoing Symptoms and Reduced Health Measures in Unicentric Castleman Disease Patients Despite Perceived-to-be Curative Surgical Excision

Freda R Coren, Mateo Sarmiento Bustamante, Sheila K Pierson, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 2709.
https://doi.org/10.1182/blood-2021-153756
Published: 2021
Journal Articles

Association between Insufficient Interleukin-6 (IL-6) Inhibition and Worsening Outcomes in COVID-19 and Idiopathic Multicentric Castleman Disease (iMCD), and a Mathematical Model to Predict Optimal Dosing to Completely Block IL-6 Activity

Jean-Francois Rossi, Hao-Chun Chiang, Zhao-Yang Lu, Kalle Levon, Frits van Rhee, Karan Kanhai, David C Fajgenbaum, Bernard Klein
Journal: Blood
Blood (2021) 138 (Supplement 1): 4004.
https://doi.org/10.1182/blood-2021-150433
Published: 2021
Journal Articles

Characterizing Mortality Associated with Idiopathic Multicentric Castleman Disease

Sheila K Pierson, Karan Kanhai, Adam Bagg, Daisy Alapat, Megan S. Lim, Mary Jo Lechowicz, Gordan Srkalovic, Thomas S. Uldrick, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 1623.
https://doi.org/10.1182/blood-2021-153397
Published: 2021
Journal Articles

Characterization of Castleman Disease Reveals Patients with Oligocentric Adenopathy and Clinicopathologic Characteristics Similar to Unicentric Castleman Disease

Sheila K Pierson, Adam Bagg, Daisy Alapat, Megan S. Lim, Mary Jo Lechowicz, Gordan Srkalovic, Thomas S. Uldrick, Frits van Rhee, David C Fajgenbaum
Journal: Blood
Blood (2021) 138 (Supplement 1): 1622.
https://doi.org/10.1182/blood-2021-153840
Published: 2021