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Journal Articles

Phase 1 Study of CD19 Targeted CD28 Costimulatory Agonist in Combination with Glofitamab to Enhance T Cell Effector Function in Relapsed/Refractory B Cell Lymphoma

Michael Dickinson, Giuseppe Gritti, Carmelo Carlo-Stella, Harriet S Walter, David Carlile, Nicole Getzmann, Samira Curdt, Emma Harrop, Abiraj Keelara, Koorosh Korfi, Remi Labatut, Francesca Michielin, Sarah Louise Mycroft, Tom Moore, Robert Nutbrown, Giuseppe Palldino, Matt Whayman, Johannes Sam, Martin Weisser, Katharina E Lechner, Franck Morschhauser, Martin Hutchings
Journal: Blood
Blood (2022) 140 (Supplement 1): 3818–3820.
https://doi.org/10.1182/blood-2022-156808
Published: 2022
Journal Articles

Glofitamab Monotherapy Induces High Complete Response Rates in Patients with Heavily Pretreated Relapsed or Refractory Mantle Cell Lymphoma

Tycel J. Phillips, Michael Dickinson, Franck Morschhauser, Emmanuel Bachy, Michael Crump, Marek Trněný, Nancy L. Bartlett, Jan Zaucha, Tomasz Wrobel, Fritz Offner, Kathryn Humphrey, Linda Lundberg, James Relf, Audrey Filézac de L'Étang, David Carlile, Ben Byrne, Naseer Qayum, Carmelo Carlo-Stella
Journal: Blood
Blood (2022) 140 (Supplement 1): 178–180.
https://doi.org/10.1182/blood-2022-157777
Published: 2022
Journal Articles

Glofitamab Step-up Dosing Induces High Response Rates in Patients (pts) with Relapsed or Refractory (R/R) Mantle Cell Lymphoma (MCL), Most of Whom Had Failed Prior Bruton's Tyrosine Kinase Inhibitor (BTKi) Therapy

Tycel Phillips, Michael Dickinson, Franck Morschhauser, Emmanuel Bachy, Michael Crump, Marek Trněný, Nancy L. Bartlett, Jan Zaucha, Kathryn Humphrey, David Perez-Callejo, Linda Lundberg, James Relf, Audrey Filézac de L'Étang, David Carlile, Emma Clark, Carmelo Carlo-Stella
Journal: Blood
Blood (2021) 138 (Supplement 1): 130.
https://doi.org/10.1182/blood-2021-148949
Published: 2021
Journal Articles

Glofitamab (Glofit) in Combination with Polatuzumab Vedotin (Pola): Phase Ib/II Preliminary Data Support Manageable Safety and Encouraging Efficacy in Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Martin Hutchings, Anna Sureda, María José Terol, Francesc Bosch Albareda, Paolo Corradini, Thomas Stauffer Larsen, Antonio Rueda Dominguez, Anesh Panchal, Alessia Bottos, David Carlile, Yanjie Wang, Audrey Filézac De L'Étang, Maneesh Tandon, Gila Sellam, Giuseppe Gritti
Journal: Blood
Blood (2021) 138 (Supplement 1): 525.
https://doi.org/10.1182/blood-2021-148359
Published: 2021
Journal Articles

Development of a Predictive Model for Cytokine Release Syndrome to Inform Risk Stratification and CRS Management Following Immunotherapy

Krishna V. Komanduri, Anton Belousov, Michelle Byrtek, Antonia Kwan, David Perez-Callejo, Chi-Chung Li, David Carlile, Bruce McCall, Tina Nielsen, Emily C. Piccione
Journal: Blood
Blood (2021) 138 (Supplement 1): 1459.
https://doi.org/10.1182/blood-2021-147303
Published: 2021
Journal Articles

Glofitamab Step-up Dosing Induces High Response Rates in Patients with Hard-to-Treat Refractory or Relapsed Non-Hodgkin Lymphoma

Martin Hutchings, MD PhD, Carmelo Carlo-Stella, MD, Emmanuel Bachy, MD PhD, Fritz C. Offner, MD PhD, Franck Morschhauser, MD PhD, Michael Crump, Gloria Iacoboni, MD, Anna Sureda Balari, MD PhD, Joaquin Martinez-Lopez, MD, Linda Lundberg, Mark Dixon, David Perez Callejo, James Relf, David Carlile, Emily Piccione, Kathryn Humphrey, Michael Dickinson, DMed Sci
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–48.
https://doi.org/10.1182/blood-2020-136044
Published: 2020
Journal Articles

Population Pharmacokinetics and Exposure-Response Analyses for Glofitamab in Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R NHL): Confirmation of Efficacy and CRS Mitigation in Patients with Step-up Dosing

Nassim Djebli, Peter N Morcos, Félix Jaminion, Elena Guerini, Nicole A Kratochwil, Nicole Justies, Eginhard Schick, Antonia Kwan, Kathryn Humphrey, Linda Lundberg, David Carlile
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-136311
Published: 2020
Journal Articles

Phase 1 study results of the type II glycoengineered humanized anti-CD20 monoclonal antibody obinutuzumab (GA101) in B-cell lymphoma patients

Clinical Trials & Observations
Gilles Salles, Franck Morschhauser, Thierry Lamy, Noel Milpied, Catherine Thieblemont, Hervé Tilly, Gabi Bieska, Elina Asikanius, David Carlile, Joe Birkett, Pavel Pisa, Guillaume Cartron
Journal: Blood
Blood (2012) 119 (22): 5126–5132.
https://doi.org/10.1182/blood-2012-01-404368
Published: 2012
Journal Articles

Pharmacokinetics of Obinutuzumab (GA101) in Patients with CD20+ Relapsed/Refractory Malignant Disease Receiving Concomitant Chemotherapy (Phase Ib Study BO21000),

David Carlile, PhD, Georgina Meneses-Lorente, PhD, Elisabeth Wassner-Fritsch, Florence Hourcade-Potelleret, PhD, Michael K. Wenger, Guillaume Cartron, MD, PhD, Umberto Vitolo, MD, John Radford, MD, Andrew Davies, Franck Morschhauser, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3704.
https://doi.org/10.1182/blood.V118.21.3704.3704
Published: 2011
Journal Articles

Pharmacokinetics of RO5072759 (GA101) In Patients with Relapsed/Refractory CD20 + Malignant Disease (Phase I/II Study BO20999)

Georgina Meneses-Lorente, PhD, David Carlile, PhD, Joe Birkett, PhD, Michael K. Wenger, MD, Guillaume Cartron, MD, PhD, Franck Morschhauser, MD, PhD, Gilles Andre Salles, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1833.
https://doi.org/10.1182/blood.V116.21.1833.1833
Published: 2010
Journal Articles

Phase I Study of RO5072759 (GA101) in Patients with Relapsed/Refractory CD20+ Non-Hodgkin Lymphoma (NHL).

Gilles Salles, MD, PhD, Franck Morschhauser, MD, PhD, Thierry Lamy, MD, PhD, Noel Milpied, MD, PhD, Catherine Thieblemont, MD, PhD, Herve Tilly, MD, Gabi Bieska, MSc, David Carlile, PhD, Guillaume Cartron, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1704.
https://doi.org/10.1182/blood.V114.22.1704.1704
Published: 2009