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David E Ambrose, BS
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Journal Articles

Long-Term Remission of CLL Sustained By Pauciclonal Anti-CD19 Chimeric Antigen Receptor T (CTL019) Cell Clones

J. Joseph Melenhorst, PhD, David L. Porter, MD, Lifeng Tian, PhD, Simon F Lacey, PhD BS, Christopher L Nobles, PhD, Joseph A Fraietta, PhD, Noelle V. Frey, MD, Irina Kulikovskaya, Minnal Gupta, Regina M Young, PhD, David E Ambrose, BS, Don L. Siegel, MD PhD, Frederic D Bushman, PhD, Carl H June, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 699.
https://doi.org/10.1182/blood-2018-99-117390
Published: 2018
Journal Articles

Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia

Joseph A Fraietta, PhD, Simon F Lacey, PhD BS, Elena Orlando, PhD, Julian Pruteanu, PhD, Mercy Gohil, Yan Wang, PhD, Alina Boesteanu, PhD, Roddy OConnor, PhD, David E Ambrose, BS, Wei-Ting Hwang, PhD, Nicholas Wilcox, Felipe Bedoya, PhD, Corin Dorfmeier, Fang Chen, PhD, Harit Parakandi, Minnal Gupta, Edward Pequignot, MS, F. Brad Johnson, PhD, Irina Kulikovskaya, Li Liu, Stefan M Lundh, BS, Jun Xu, PhD, Megan M Davis, PhD, Regina M Young, PhD, Bruce L Levine, PhD, Don L. Siegel, MD PhD, Alexander Huang, PhD, E. John Wherry, PhD, Jing Zhou, Patrick Paczkowski, Sean Mackay, Jennifer Brogdon, PhD, Hans Bitter, PhD, David L Porter, MD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3181.
https://doi.org/10.1182/blood.V130.Suppl_1.3181.3181
Published: 2017
Journal Articles

Safety and Efficacy of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA) with Cyclophosphamide Conditioning for Refractory Multiple Myeloma (MM)

Adam D. Cohen, MD, Alfred L. Garfall, MD, Edward A. Stadtmauer, MD FACP, Simon F Lacey, PhD BS, Eric Lancaster, Dan T. Vogl, MD, Brendan M Weiss, MD, David E Ambrose, BS, Anne Marie Nelson, Fang Chen, PhD, Gabriela Plesa, MD, Irina Kulikovskaya, Vanessa Gonzalez, Minnal Gupta, Regina M Young, PhD, Karen Dengel, BSN, RN, Laura O'keefe, Samantha Le, Celeste Richardson, PhD, Randi E. Isaacs, MD, J. Joseph Melenhorst, PhD, Bruce L Levine, PhD, Carl H June, MD, Michael C. Milone, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 505.
https://doi.org/10.1182/blood.V130.Suppl_1.505.505
Published: 2017
Journal Articles

Cars in Leukemia: Relapse with Antigen-Negative Leukemia Originating from a Single B Cell Expressing the Leukemia-Targeting CAR

Simon Francis Lacey, PhD BS, Jun Xu, PhD, Marco Ruella, MD, David M. Barrett, MD PhD, Irina Kulikovskaya, PhD, David E Ambrose, BS, Prachi R. Patel, BS, Tyler Reich, John Scholler, Farzana Nazimuddin, Joseph A. Fraietta, PhD, Shannon L Maude, MD PhD, Saar I. Gill, MD PhD, Bruce L Levine, PhD, Christopher L Nobles, PhD, Frederic D Bushman, PhD, Elena Orlando, PhD, Stephan A. Grupp, MD PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 281.
https://doi.org/10.1182/blood.V128.22.281.281
Published: 2016
Journal Articles

B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA) for Multiple Myeloma (MM): Initial Safety and Efficacy from a Phase I Study

Adam D. Cohen, MD, Alfred L. Garfall, MD, Edward A Stadtmauer, MD, Simon Francis Lacey, PhD BS, Eric Lancaster, MD PhD, Dan T. Vogl, MD, Karen Dengel, BSN, RN, David E Ambrose, BS, Fang Chen, PhD, Gabriela Plesa, PhD, Irina Kulikovskaya, PhD, Vanessa E Gonzalez, M.B.A, Minnal Gupta, MSc, Regina M Young, PhD, Tenesia Carey, Regina Ferthio, Brendan M. Weiss, MD, Celeste Richardson, PhD, Randi E. Isaacs, MD, J. Joseph Melenhorst, PhD, Bruce L. Levine, PhD, Carl H June, MD, Michael C. Milone, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1147.
https://doi.org/10.1182/blood.V128.22.1147.1147
Published: 2016
Journal Articles

Biomarkers of Response to Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy in Patients with Chronic Lymphocytic Leukemia

Joseph A. Fraietta, PhD, Simon F. Lacey, PhD, Nicholas S Wilcox, Felipe Bedoya, PhD, Fang Chen, PhD, Elena Orlando, PhD, Jennifer L Brogdon, PhD, Wei-Ting Hwang, PhD, Noelle Frey, MD MS, Regina M Young, PhD, Edward Pequignot, M.S., David E Ambrose, BS, Bruce L Levine, PhD, Hans Bitter, PhD, David L Porter, MD, Jun Xu, PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 57.
https://doi.org/10.1182/blood.V128.22.57.57
Published: 2016
Journal Articles

Posterior Reversible Encephalopathy Syndrome (PRES) after Infusion of Anti-Bcma CAR T Cells (CART-BCMA) for Multiple Myeloma: Successful Treatment with Cyclophosphamide

Alfred L. Garfall, MD, Eric Lancaster, MD PhD, Edward A Stadtmauer, MD, Simon F. Lacey, PhD, Karen Dengel, BSN, RN, David E Ambrose, BS, Fang Chen, PhD, Minnal Gupta, MSc, Irina Kulikovskaya, PhD, Dan T. Vogl, MD, Gabriela Plesa, PhD, Brendan M Weiss, MD, Regina Ferthio, Celeste Richardson, PhD, Jan Joseph Melenhorst, PhD, Bruce L Levine, PhD, Carl H June, MD, Michael Milone, MD PhD, Adam D. Cohen, MD
Journal: Blood
Blood (2016) 128 (22): 5702.
https://doi.org/10.1182/blood.V128.22.5702.5702
Published: 2016
Journal Articles

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CTL019) in Conjunction with Salvage Autologous Stem Cell Transplantation for Advanced Multiple Myeloma

Alfred L. Garfall, MD, Edward A Stadtmauer, MD, Marcela V. Maus, MD PhD, Wei-Ting Hwang, PhD, Dan T. Vogl, MD, Adam D. Cohen, MD, Brendan M Weiss, MD, David L Porter, MD, Noelle Frey, MD MS, Michael Milone, MD PhD, Patricia Mangan, MSN, CRNP, Maria Krevvata, PhD, Emily Ayers, MD, Karen Dengel, BSN, RN, Naseem DS Kerr, MPH, Simon F. Lacey, PhD, Jan Joseph Melenhorst, PhD, David E Ambrose, BS, Fang Chen, PhD, Vanessa E Gonzalez, M.B.A, Irina Kulikovskaya, PhD, Minnal Gupta, MSc, Jeffrey Finklestein, MSc, Anne Lamontagne, MSc, Matthew O'Rourke, MSc, Megan Suhoski Davis, PhD, Alexander Malykhin, MSc, Bruce L Levine, PhD, Carl H June, MD
Journal: Blood
Blood (2016) 128 (22): 974.
https://doi.org/10.1182/blood.V128.22.974.974
Published: 2016