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Dean W. Felsher
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Journal Articles

The MYC oncogene is a global regulator of the immune response

Stephanie C. Casey, Virginie Baylot, Dean W. Felsher
Journal: Blood
Blood (2018) 131 (18): 2007–2015.
https://doi.org/10.1182/blood-2017-11-742577
Published: 2018
Journal Articles

Intratumoral Administration of the Immunotherapeutic Combination Anti-ctla4, Anti-cd137 and Anti-ox40: Comparison to Systemic Administration, Peri-Draining Lymph Node Injection, and Cellular Vaccine in a Mouse Lymphoma Model

Jonathan P. O. Hebb, FRCPC, MD MSC, Adriane Mosley, BSc, Felipe Vences Catalan, Peter Ellmark, Per Norlen, Dean W Felsher, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4172.
https://doi.org/10.1182/blood.V128.22.4172.4172
Published: 2016
Journal Articles

Leukemia Cell Differentiation upon Targeted Therapy Revealed By a Systems Biology Approach

Yulin Li, MD PhD, Jun Seita, MD, PhD, Dean W Felsher, MD PhD, David Dill, PhD
Journal: Blood
Blood (2014) 124 (21): 5202.
https://doi.org/10.1182/blood.V124.21.5202.5202
Published: 2014
Journal Articles

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Stephanie Beurlet, Nader Omidvar, Petra Gorombei, Patricia Krief, Carole Le Pogam, Niclas Setterblad, Pierre de la Grange, Christophe Leboeuf, Anne Janin, Maria-Elena Noguera, Florence Hervatin, Laure Sarda-Mantel, Marina Konopleva, Michael Andreeff, Andrea W. Tu, Alice C. Fan, Dean W. Felsher, Anthony Whetton, Marika Pla, Robert West, Pierre Fenaux, Christine Chomienne, Rose Ann Padua
Journal: Blood
Blood (2013) 122 (16): 2864–2876.
https://doi.org/10.1182/blood-2012-07-445635
Published: 2013
Includes: Supplemental data
Journal Articles

A Novel Nano-Immunoassay (NIA) Reveals Inhibition of PI3K and MAPK Pathways in CD34+ Bone Marrow Cells of Patients with Myelodysplastic Syndrome (MDS) Treated with the Multi-Kinase Inhibitor On 01910.Na (Rigosertib),

Alice C Fan, MD, Liwen Xu, PhD, Kunju J Sridhar, PhD, Mai Tran, Prajna Banerjee, PhD, John P. Renschler, Radha Tripuraneni, MD, Francois Wilhelm, MD, PhD., Peter L. Greenberg, MD, Dean W. Felsher, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3808.
https://doi.org/10.1182/blood.V118.21.3808.3808
Published: 2011
Journal Articles

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

Rose Ann Padua, PhD, Stephanie Beurlet, DMV, Patricia Krief, PhD, Nader Omidvar, PhD, Carole Le Pogam, BSc, Didier Auboeuf, PhD, Pierre de la Grange, PhD, Annie Soulie, Anne Janin, MD, PhD, Maria-Elena Noguera, MD, Pascal Merlet, MD, Laure Sarda-Mantel, MD, PhD, Pierre Fenaux, MD, PhD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Andrea Tu, PhD, Phoebe Yang, PhD, Alice C. Fan, MD, Scott C. Kogan, MD, Irving L. Weissman, MD, Dean W. Felsher, MD, PhD, Marika Pla, PhD, Robert West, PhD, Christine Chomienne, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3308.
https://doi.org/10.1182/blood.V116.21.3308.3308
Published: 2010
Journal Articles

Treatment of Higher Risk Myelodysplastic Syndrome Patients Unresponsive to Hypomethylating Agents with ON 01910.Na

Mahesh Seetharam, MD, Mai Tran, Alice C. Fan, MD, Liwen Xu, PhD, John P. Renschler, Dean W. Felsher, MD, PhD, Kunju Sridhar, PhD, Francois Wilhelm, MD, PhD., Peter L. Greenberg, MD
Journal: Blood
Blood (2010) 116 (21): 4010.
https://doi.org/10.1182/blood.V116.21.4010.4010
Published: 2010
Journal Articles

Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia

Sylvie Giuriato, Marianne Foisseau, Emilie Dejean, Dean W. Felsher, Talal Al Saati, Cécile Demur, Ashraf Ragab, Anna Kruczynski, Claudine Schiff, Georges Delsol, Fabienne Meggetto
Journal: Blood
Blood (2010) 115 (20): 4061–4070.
https://doi.org/10.1182/blood-2008-06-163386
Published: 2010
Includes: Supplemental data
Journal Articles

Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC -induced lymphomagenesis

Catherine M. Shachaf, Omar D. Perez, Sawsan Youssef, Alice C. Fan, Sailaja Elchuri, Matthew J. Goldstein, Amy E. Shirer, Orr Sharpe, Joy Chen, Dennis J. Mitchell, Maria Chang, Garry P. Nolan, Lawrence Steinman, Dean W. Felsher
Journal: Blood
Blood (2007) 110 (7): 2674–2684.
https://doi.org/10.1182/blood-2006-09-048033
Published: 2007
Includes: Supplemental data
Journal Articles

Nano-Fluidic Detection of Oncoprotein Signaling in Preclinical and Patient Lymphoma Samples.

Alice C. Fan, MD, Debabrita Deb-Basu, Ph.D., Melissa Horoschak, Amy Shirer, M.D., David Voehringer, Ph.D, Roger O’Neill, Ph.D, Dean W. Felsher, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2527.
https://doi.org/10.1182/blood.V108.11.2527.2527
Published: 2006
Journal Articles

Two Oncogenic Hits Are Required To Initiate Lymphomagenesis in Adult, but Not Neonatal Hosts.

Alice C. Fan, MD, Sylvie Giuriato, PhD, Asa Karlsson, Ph.D, Rose Ann Padua, Ph.D, Dean W. Felsher, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2604.
https://doi.org/10.1182/blood.V106.11.2604.2604
Published: 2005
Journal Articles

MYC Inactivation Induces Tumor Regression through the Recovery of a Functional DNA Damage Response.

Karen Rabin, MD, Sylvie Giuriato, PhD, Suma Ray, PhD, Dean W. Felsher, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1534.
https://doi.org/10.1182/blood.V104.11.1534.1534
Published: 2004
Journal Articles

Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

Åsa Karlsson, Sylvie Giuriato, Flora Tang, Jingly Fung-Weier, Göran Levan, Dean W. Felsher
Journal: Blood
Blood (2003) 101 (7): 2797–2803.
https://doi.org/10.1182/blood-2002-10-3091
Published: 2003