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Deborah White
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Journal Articles

Characterization of Leukemias with ETV6-ABL1 Fusion

Marketa Zaliova, Anthony V. Moorman, Giovanni Cazzaniga, Martin Stanulla, Richard C. Harvey, Kathryn G. Roberts, Sue L. Heatley, Mignon L. Loh, Marina Konopleva, I-Ming Chen, Olga Zimmermannova, Claire Schwab, Owen Smith, Marie-Joelle Mozziconacci, Christian Chabannon, Myungshin Kim, J.H. Frederik Falkenburg, Alice Norton, Karen Marshall, Oskar A. Haas, Julia Starkova, Jan Stuchly, Stephen P. Hunger, Deborah White, Charles G. Mullighan, Cheryl L Willman, Jan Stary, Jan Trka, Jan Zuna
Journal: Blood
Blood (2015) 126 (23): 84.
https://doi.org/10.1182/blood.V126.23.84.84
Published: 2015
Journal Articles

The Depth Of In Vivo Kinase Inhibition Achieved Over The First Month Of Nilotinib Therapy Predicts For Subsequent Molecular Response, and Is Closely Related To Nilotinib Plasma Levels

Deborah White, PhD. FFSc (RCPA), Verity Saunders, BScHons, Laura Eadie, PhD, Yeung David, Timothy P. Hughes, MD, MBBS
Journal: Blood
Blood (2013) 122 (21): 256.
https://doi.org/10.1182/blood.V122.21.256.256
Published: 2013
Journal Articles

SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome–positive cells derived from patients with chronic myeloid leukemia

Nicola Esposito, Irene Colavita, Concetta Quintarelli, Agostino Rodeo Sica, Anna Lucia Peluso, Luigia Luciano, Marco Picardi, Luigi Del Vecchio, Tonia Buonomo, Timothy P. Hughes, Deborah White, Jerald P. Radich, Domenico Russo, Susan Branford, Giuseppe Saglio, Junia V. Melo, Rosanna Martinelli, Margherita Ruoppolo, Thea Kalebic, Giovanni Martinelli, Fabrizio Pane
Journal: Blood
Blood (2011) 118 (13): 3634–3644.
https://doi.org/10.1182/blood-2011-03-341073
Published: 2011
Includes: Supplemental data
Journal Articles

Enhancing the Functional Activity of the OCT-1 Influx Pump May Overcome the Negative Impact of Low OCT-1 Activity in Imatinib Treated CML Patients

Deborah White, PhD, Phuong Dang, Kelvin Groot Obbink, Amity Frede, Chung Kok, Timothy P Hughes, MD, Richard D’Andrea, PhD
Journal: Blood
Blood (2008) 112 (11): 723.
https://doi.org/10.1182/blood.V112.11.723.723
Published: 2008
Journal Articles

IKZF1 (Ikaros) Deletions Are a Hallmark of BCR-ABL1 Positive Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS, MD, Christopher B. Miller, BS, Letha A. Phillips, BS, James Dalton, BS, Jing Ma, PhD, Ina Radtke, MD, PhD, Deborah White, BSc(Hons), Timothy P. Hughes, MBBS, PhD, Michelle M. Le Beau, MD, PhD, Sheila A. Shurtleff, PhD, James R. Downing, MD
Journal: Blood
Blood (2007) 110 (11): 721.
https://doi.org/10.1182/blood.V110.11.721.721
Published: 2007
Journal Articles

Molecular Response to Imatinib Is Dependent on Dose in CML Patients with Low OCT-1 Influx Activity. Patients with High Activity May Respond Equally Well to Standard or Increased Dose Imatinib.

Deborah White, Verity Saunders, Phuong Dang, Amity Venables, Steph Zrim, John Reynolds, Steven Quinn, Andrew Zannettino, Timothy Hughes
Journal: Blood
Blood (2006) 108 (11): 738.
https://doi.org/10.1182/blood.V108.11.738.738
Published: 2006
Journal Articles

ABCB1 Overexpression May Predispose Imatinib Treated CML Patients to the Development of Abl Kinase Domain Mutations, and May Be an Important Contributor to Acquired Resistance.

Deborah White, Phuong Dang, Amity Venables, Verity Saunders, Stephanie Zrim, Andrew Zannettino, Peter Diamond, Steven Quinn, Luen Bik To, Timothy Hughes
Journal: Blood
Blood (2006) 108 (11): 2144.
https://doi.org/10.1182/blood.V108.11.2144.2144
Published: 2006
Journal Articles

In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CML

Clinical Trials & Observations
Deborah White, Verity Saunders, A. Bruce Lyons, Susan Branford, Andrew Grigg, L. Bik To, Timothy Hughes
Journal: Blood
Blood (2005) 106 (7): 2520–2526.
https://doi.org/10.1182/blood-2005-03-1103
Published: 2005