Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 20

Sort by

Sort Order Select

Journal Articles

Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia

Christina Wu, PhD, Emanuela M. Ghia, PhD, Fitzgerald Lao, Minya Pu, PhD, Karen Messer, PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Dennis A. Carson, MD, Michael Y. Choi, MD

Blood (2018) 132 (Supplement 1): 3143.

https://doi.org/10.1182/blood-2018-99-119292

Published: 2018

Journal Articles

Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Ekaterina Vinogradova, PhD, Fitzgerald Lao, Emily Nan, Katie Ta, Karen Messer, PhD, Michael Choi, MD, Benjamin F. Cravatt, PhD, Dennis A. Carson, MD

Blood (2017) 130 (Supplement 1): 3838.

https://doi.org/10.1182/blood.V130.Suppl_1.3838.3838

Published: 2017

Journal Articles

Inhibition of Casein Kinase 2 Impairs Wnt Signaling and Cell Survival in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Fitzgerald S Lao, BS, Emily Nan, Hongying Li, PhD, Michael Y. Choi, MD, Karen Messer, PhD, Dennis A. Carson, MD

Blood (2016) 128 (22): 2050.

https://doi.org/10.1182/blood.V128.22.2050.2050

Published: 2016

Journal Articles

Pharmacologic Modulation of STAT1 and Wnt Signaling in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Fitzgerald S Lao, BS, Michael Y. Choi, MD, Dennis A. Carson, MD

Blood (2015) 126 (23): 4150.

https://doi.org/10.1182/blood.V126.23.4150.4150

Published: 2015

Journal Articles

Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib

Christina C.N. Wu, PhD, Fitzgerald Lao, Hongying Li, PhD, Laura Rassenti, PhD, Thomas J. Kipps, MD, Karen Messer, PhD, Dennis A. Carson, MD, Michael Y. Choi, MD

Blood (2014) 124 (21): 4683.

https://doi.org/10.1182/blood.V124.21.4683.4683

Published: 2014

Journal Articles

Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib

Christina C.N. Wu, PhD, Michael Y. Choi, MD, Fitzgerald Lao, Thomas J. Kipps, MD, PhD, Dennis A. Carson, M.D.

Blood (2013) 122 (21): 5306.

https://doi.org/10.1182/blood.V122.21.5306.5306

Published: 2013

Journal Articles

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Jian Yu, PhD, Bing Cui, Ph.D., George F. Widhopf, II, PhD, Liguang Chen, MD, PhD, Laura Rassenti, PhD, Zhengran Wang, BS, Shuyu Ma, BS, Tomoko Hayashi, M.D., Ph.D., Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 4174.

https://doi.org/10.1182/blood.V122.21.4174.4174

Published: 2013

Journal Articles

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Bing Cui, Ph.D, George F. Widhopf, II, PhD, Charles E. Prussak, Ph.D., Christina C.N. Wu, PhD, Anil Sadarangani, PhD, Suping Zhang, PhD, Fitzgerald Lao, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D, Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 1637.

https://doi.org/10.1182/blood.V122.21.1637.1637

Published: 2013

Journal Articles

Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Christina C.N. Wu, PhD, Jian Yu, PhD, Fitzgerald Lao, Rommel Tawatao, Rongrong Wu, Esther Avery, B.S., Anil Sadarangani, PhD, Charles Prussak, PhD, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 2873.

https://doi.org/10.1182/blood.V122.21.2873.2873

Published: 2013

Journal Articles

A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal.

Larissa Balaian, Ph.D., Anil Sadarangani, Ph.D., George F. Widhopf, II, PhD, Rui-kun Zhong, MD, Charles Prussak, PhD, Marco A. Marra, PhD, John E Dick, PhD, Mark D. Minden, MD, PhD, Edward D. Ball, M.D., Dennis A. Carson, M.D., Catriona Jamieson, MD, PhD, Thomas J. Kipps, MD, PhD

Blood (2012) 120 (21): 2560.

https://doi.org/10.1182/blood.V120.21.2560.2560

Published: 2012

Journal Articles

Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Eva Hellqvist, Ph.D, Christina C.N. Wu, Ph.D., George F. Widhopf, II, PhD, Alice Shih, Rommel Tawatao, Fitzgerald Lao, Bing Cui, Ph.D., Charles Prussak, PhD, Anil Sadarangani, Ph.D., Dennis A. Carson, M.D., Catriona Jamieson, MD, PhD, Thomas J. Kipps, MD, PhD

Blood (2012) 120 (21): 3886.

https://doi.org/10.1182/blood.V120.21.3886.3886

Published: 2012

Journal Articles

Selective Inhibition of Activated B-Cell Lymphoma Cells by a Novel Small Molecule Inhibitor of NF-κB

John T, Norton, PhD, Tomoko Hayashi, M.D., Ph.D., Raymond P. Wu, Ph.D., Howard Cottam, PhD, Dennis A. Carson, M.D.

Blood (2011) 118 (21): 2498.

https://doi.org/10.1182/blood.V118.21.2498.2498

Published: 2011

Journal Articles

Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia,

Raymond P. Wu, Ph.D., Christina C.N. Wu, Ph.D., Tomoko Hayashi, M.D., Ph.D., Laura Z. Rassenti, Ph.D., Thomas J. Kipps, M.D., Ph.D, Dennis A. Carson, M.D.

Blood (2011) 118 (21): 3867.

https://doi.org/10.1182/blood.V118.21.3867.3867

Published: 2011

Journal Articles

Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis,

Liguang Chen, MD, PhD, George Chen, B.S., Jessie-Farah Fecteau, Ph.D., Greg Coffey, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas Kipps, MD

Blood (2011) 118 (21): 3875.

https://doi.org/10.1182/blood.V118.21.3875.3875

Published: 2011

Journal Articles

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Suping Zhang, PhD, Christina C.N. Wu, Ph.D., Jessie-Farah Fecteau, Ph.D., Bing Cui, PhD, Rongrong Wu, Laura Z. Rassenti, Ph.D., Fitzgerald S. Lao, B.S., Rommel Tawatao, B.S., Stefan Weigland, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 927.

https://doi.org/10.1182/blood.V118.21.927.927

Published: 2011

Journal Articles

Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53

Michael Y. Choi, MD, Johanna Melo Cardenas, BSc, Desheng Lu, MD, PhD, Jian Yu, PhD, E. Paige Stout, PhD, Raymond P. Wu, Ph.D., John M Horton, B.S., Allison Gomez, Julio A. Diaz-Perez, M.D., M.S., Dennis A. Carson, M.D., Tadeusz F. Molinski, PhD, Thomas J. Kipps, M.D., Ph.D, Januario E. Castro, M.D.

Blood (2011) 118 (21): 1786.

https://doi.org/10.1182/blood.V118.21.1786.1786

Published: 2011

Journal Articles

Oxidative Stress Response and Cytotoxicity of Electrophilic Compounds in Primary Human Chronic Lymphocytic Leukemia.

Raymond P Wu, Ph.D., Tomoko Hayashi, M.D., Ph.D., Shiyin Yao, Christina C.N. Wu, Ph.D., Howard B Cottam, Ph.D., Michael Rosenbach, Richard B. Schwab, MD, Dennis A. Carson, MD

Blood (2009) 114 (22): 3444.

https://doi.org/10.1182/blood.V114.22.3444.3444

Published: 2009

Journal Articles

Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells.

Irene M. Pedersen, Ph.D., Frederic Luciano, Ph.D., Xiao-kun Zhang, Ph.D., Carlo M. Croce, Ph.D., Thomas J. Kipps, M.D., Ph.D., Dennis A. Carson, M.D., Ph.D., John C. Reed, M.D., Ph.D.

Blood (2004) 104 (11): 967.

https://doi.org/10.1182/blood.V104.11.967.967

Published: 2004

Journal Articles

Restricted Expression of the Orphan Tyrosine Kinase Receptor ROR1 in Chronic Lymphocytic Leukemia.

Tetsuya Fukuda, MD, PhD, Desheng Lu, MD, PhD, Dennis A. Carson, MD, Thomas J. Kipps, MD, PhD

Blood (2004) 104 (11): 772.

https://doi.org/10.1182/blood.V104.11.772.772

Published: 2004

Journal Articles

Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

Davide Genini, Souichi Adachi, Qi Chao, David W. Rose, Carlos J. Carrera, Howard B. Cottam, Dennis A. Carson, Lorenzo M. Leoni

Blood (2000) 96 (10): 3537–3543.

https://doi.org/10.1182/blood.V96.10.3537

Published: 2000

NARROW

Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia

Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia

Inhibition of Casein Kinase 2 Impairs Wnt Signaling and Cell Survival in Chronic Lymphocytic Leukemia

Pharmacologic Modulation of STAT1 and Wnt Signaling in Chronic Lymphocytic Leukemia

Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib

Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal.

Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Selective Inhibition of Activated B-Cell Lymphoma Cells by a Novel Small Molecule Inhibitor of NF-κB

Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia,

Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis,

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53

Oxidative Stress Response and Cytotoxicity of Electrophilic Compounds in Primary Human Chronic Lymphocytic Leukemia.

Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells.

Restricted Expression of the Orphan Tyrosine Kinase Receptor ROR1 in Chronic Lymphocytic Leukemia.

Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only