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Journal Articles

Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers

Pingping Zheng, PhD, Adrianne E Vasey, Jeanette Baker, Bettina Iliopoulou, PhD, Dennis B Leveson-Gower, PhD, Antonio Pierini, Dominik Schneidawind, MD, Xiaoqing You, PhD, Katie Hsu, Robert Negrin, MD, Everett Meyer, MD PhD

Blood (2015) 126 (23): 4284.

https://doi.org/10.1182/blood.V126.23.4284.4284

Published: 2015

Journal Articles

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Antonio Pierini, MD, Hidekazu Nishikii, MD PhD, Yuqiong Pan, MD, Jeanette Baker, PhD, Dennis B Leveson-Gower, PhD, Mareike Florek, MD, Robert Negrin, MD

Blood (2014) 124 (21): 4322.

https://doi.org/10.1182/blood.V124.21.4322.4322

Published: 2014

Journal Articles

Loss of CD62L Expression in CD4+FoxP3+ Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models

Mareike Florek, MD, Dominik Schneidawind, MD, Jeanette Baker, PhD, Antonio Pierini, MD, Dennis B Leveson-Gower, PhD, Yuqiong Pan, MD, Robert S. Negrin, MD, Everett H. Meyer, MD PhD

Blood (2014) 124 (21): 2427.

https://doi.org/10.1182/blood.V124.21.2427.2427

Published: 2014

Journal Articles

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Mareike Florek, Emanuela I. Sega, Dennis B. Leveson-Gower, Jeanette Baker, Antonia M. S. Müller, Dominik Schneidawind, Everett Meyer, Robert S. Negrin

Blood (2014) 124 (11): 1832–1842.

https://doi.org/10.1182/blood-2014-02-555128

Published: 2014

Includes: Supplemental data

Journal Articles

Mast cells suppress murine GVHD in a mechanism independent of CD4 + CD25 + regulatory T cells

Dennis B. Leveson-Gower, Emanuela I. Sega, Janet Kalesnikoff, Mareike Florek, Yuqiong Pan, Antonio Pierini, Stephen J. Galli, Robert S. Negrin

Blood (2013) 122 (22): 3659–3665.

https://doi.org/10.1182/blood-2013-08-519157

Published: 2013

Includes: Supplemental data

Journal Articles

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

Antonio Pierini, MD, Hidekazu Nishikii, MD, PhD, Mareike Florek, MD, Dennis B Leveson-Gower, PhD, Yuqiong Pan, MD, Byung-Su Kim, MD, Jeanette Baker, PhD, Robert Negrin, MD

Blood (2013) 122 (21): 1996.

https://doi.org/10.1182/blood.V122.21.1996.1996

Published: 2013

Journal Articles

The Inhibitory Receptor LAG-3 Is Not Essential for Regulatory T Cells Function but Influences Donor T Cell Potency in Acute Graft-Versus-Host-Disease

Emanuela I Sega, PhD, Dennis B Leveson-Gower, PhD, Mareike Florek, MD, Robert S Negrin, MD

Blood (2011) 118 (21): 1900.

https://doi.org/10.1182/blood.V118.21.1900.1900

Published: 2011

Journal Articles

A Novel Model of Pre-Emptive ECP Treatment Shows Significant Reduction of Gvhd-Related Mortality In Mice,

Mareike Florek, MD, Emanuela I Sega, PhD, Antonia MS Mueller, MD, Dennis B Leveson-Gower, PhD, Judith A Shizuru, MD PhD, Robert S Negrin, MD

Blood (2011) 118 (21): 4025.

https://doi.org/10.1182/blood.V118.21.4025.4025

Published: 2011

Journal Articles

IL-17 Gene Ablation Does Not Impact Treg-Mediated Suppression of Graft-Versus-Host Disease Following Bone Marrow Transplantation,

Lucrezia Colonna, PhD, Mareike Florek, MD, Dennis B Leveson-Gower, PhD, Emanuela I Sega, PhD, Robert Zeiser, M.D., Martin Buess, MD, Robert S Negrin, MD

Blood (2011) 118 (21): 4037.

https://doi.org/10.1182/blood.V118.21.4037.4037

Published: 2011

Journal Articles

Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4 + CD25 + Foxp3 + regulatory T cells

Ho-Jin Shin, Jeanette Baker, Dennis B. Leveson-Gower, Aaron T. Smith, Emanuela I. Sega, Robert S. Negrin

Blood (2011) 118 (8): 2342–2350.

https://doi.org/10.1182/blood-2010-10-313684

Published: 2011

Journal Articles

Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4–dependent mechanism

Dennis B. Leveson-Gower, Janelle A. Olson, Emanuela I. Sega, Richard H. Luong, Jeanette Baker, Robert Zeiser, Robert S. Negrin

Blood (2011) 117 (11): 3220–3229.

https://doi.org/10.1182/blood-2010-08-303008

Published: 2011

Journal Articles

Similarities In the Initial Events of Murine Gvhd Across Minor. as Compared to Major, Histocompatibility Barriers.

Adrianne E Vasey, Jeanette B Baker, Dennis B Leveson-Gower, Robert Negrin, MD

Blood (2010) 116 (21): 3750.

https://doi.org/10.1182/blood.V116.21.3750.3750

Published: 2010

Journal Articles

Mast Cells Reduce Gvhd Severity In Allogeneic Transplantation by Reducing the Proliferation of Conventional T Cells

Dennis B Leveson-Gower, Emanuela I Sega, Janet Kalesnikoff, Mareike Florek, Stephen J Galli, Robert Negrin, MD

Blood (2010) 116 (21): 243.

https://doi.org/10.1182/blood.V116.21.243.243

Published: 2010

Journal Articles

NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

Janelle A. Olson, Dennis B. Leveson-Gower, Saar Gill, Jeanette Baker, Andreas Beilhack, Robert S. Negrin

Blood (2010) 115 (21): 4293–4301.

https://doi.org/10.1182/blood-2009-05-222190

Published: 2010

Journal Articles

NK Cells Suppress Gvhd by Directly Inhibiting Activated Alloreactive T Cells through An NKG2D-Mediated Mechanism

Janelle A Olson, Dennis B Leveson-Gower, PhD, Jeanette Baker, Andreas Beilhack, MD, Robert Negrin, MD

Blood (2008) 112 (11): 61.

https://doi.org/10.1182/blood.V112.11.61.61

Published: 2008

Journal Articles

Differential impact of mammalian target of rapamycin inhibition on CD4 + CD25 + Foxp3 + regulatory T cells compared with conventional CD4 + T cells

Robert Zeiser, Dennis B. Leveson-Gower, Elizabeth A. Zambricki, Neeraja Kambham, Andreas Beilhack, John Loh, Jing-Zhou Hou, Robert S. Negrin

Blood (2008) 111 (1): 453–462.

https://doi.org/10.1182/blood-2007-06-094482

Published: 2008

Journal Articles

Differential Impact of Host Derived Interleukin-18 on Regulatory and Conventional T Cell Expansion Following Murine Allogeneic Hematopoietic Cell Transplantation.

Robert Zeiser, MD, Elizabeth A. Zambricki, Dennis B. Leveson-Gower, PhD, Andreas Beilhack, MD, Neeraja Kambham, MD, Robert S. Negrin, MD

Blood (2007) 110 (11): 3262.

https://doi.org/10.1182/blood.V110.11.3262.3262

Published: 2007

Journal Articles

NKT Cells Are Potent Regulators of GVHD Following Adoptive Transfer in Allogeneic BMT.

Dennis B. Leveson-Gower, PhD, Janelle A. Olson, Jeanette Baker, PhD, Robert Zeiser, MD, Andreas Beilhack, MD, Robert Negrin, MD

Blood (2007) 110 (11): 353.

https://doi.org/10.1182/blood.V110.11.353.353

Published: 2007

Journal Articles

NK Cells Induce Alloreactive Donor T Cell Apoptosis and Decrease Proliferation in GVHD Induction.

Janelle A. Olson, Dennis B. Leveson-Gower, PhD, Andreas Beilhack, MD, Robert S. Negrin, MD

Blood (2007) 110 (11): 2162.

https://doi.org/10.1182/blood.V110.11.2162.2162

Published: 2007

Journal Articles

Impact of mTOR Inhibition on FoxP3+ Regulatory T Cells as Compared to Conventional T Cells after Allogeneic Bone Marrow Transplantation.

Robert Zeiser, MD, Dennis B. Leveson-Gower, Ph.D., Elizabeth A. Zambricki, Jing-Zhou Hou, M.D., Ph.D., Robert Negrin, M.D.

Blood (2006) 108 (11): 448.

https://doi.org/10.1182/blood.V108.11.448.448

Published: 2006

NARROW

Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Loss of CD62L Expression in CD4+FoxP3+ Regulatory T Cells Following Freeze-and-Thaw Prevents Protection Against GVHD in Murine Models

Autologous apoptotic cells preceding transplantation enhance survival in lethal murine graft-versus-host models

Mast cells suppress murine GVHD in a mechanism independent of CD4 + CD25 + regulatory T cells

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

The Inhibitory Receptor LAG-3 Is Not Essential for Regulatory T Cells Function but Influences Donor T Cell Potency in Acute Graft-Versus-Host-Disease

A Novel Model of Pre-Emptive ECP Treatment Shows Significant Reduction of Gvhd-Related Mortality In Mice,

IL-17 Gene Ablation Does Not Impact Treg-Mediated Suppression of Graft-Versus-Host Disease Following Bone Marrow Transplantation,

Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4 + CD25 + Foxp3 + regulatory T cells

Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4–dependent mechanism

Similarities In the Initial Events of Murine Gvhd Across Minor. as Compared to Major, Histocompatibility Barriers.

Mast Cells Reduce Gvhd Severity In Allogeneic Transplantation by Reducing the Proliferation of Conventional T Cells

NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

NK Cells Suppress Gvhd by Directly Inhibiting Activated Alloreactive T Cells through An NKG2D-Mediated Mechanism

Differential impact of mammalian target of rapamycin inhibition on CD4 + CD25 + Foxp3 + regulatory T cells compared with conventional CD4 + T cells

Differential Impact of Host Derived Interleukin-18 on Regulatory and Conventional T Cell Expansion Following Murine Allogeneic Hematopoietic Cell Transplantation.

NKT Cells Are Potent Regulators of GVHD Following Adoptive Transfer in Allogeneic BMT.

NK Cells Induce Alloreactive Donor T Cell Apoptosis and Decrease Proliferation in GVHD Induction.

Impact of mTOR Inhibition on FoxP3+ Regulatory T Cells as Compared to Conventional T Cells after Allogeneic Bone Marrow Transplantation.

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American Society of Hematology

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American Society of Hematology

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