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Derek S. Sim
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Journal Articles

Selective Modulation of Activated Protein C Activities By an Exosite-Specific Nanobody Library

Derek S Sim, Meenal Shukla, Cornell R Mallari, Doug Schneider, Maxine Bauzon, Terry W Hermiston, Laurent O. Mosnier
Journal: Blood
Blood (2022) 140 (Supplement 1): 973–974.
https://doi.org/10.1182/blood-2022-158855
Published: 2022
Journal Articles

CT-001, a Rapid Clearing Factor VIIa, Provides Pro-Hemostatic Activity to Reduce Blood Loss in Coagulopathic Conditions Induced By Activated Protein C

Derek S Sim, Cornell R Mallari, Maxine Bauzon, Terry W Hermiston
Journal: Blood
Blood (2022) 140 (Supplement 1): 5574–5575.
https://doi.org/10.1182/blood-2022-169537
Published: 2022
Journal Articles

Site-Directed Pegylation of BDD FVIII (BAY 94-9027) Does Not Alter the Ability of the Molecule to Generate Thrombin, Activate Factor X or Become Inactivated By Activated Protein C

Subramanian Yegneswaran, PhD, Xiaoqiao Jiang, BS, Pooja Yesantharao, Ji-Yun Kim, PhD, Lilley Leong, PhD MS, Derek S Sim, PhD, Chandra Patel, PhD, Katalin Zsofia Kauser, PhD MD DSc
Journal: Blood
Blood (2014) 124 (21): 1492.
https://doi.org/10.1182/blood.V124.21.1492.1492
Published: 2014
Journal Articles

Reduced Polyethylene Glycol-Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective Peg Steric Modulation without Affecting Potency

Eric Blasko, Lilley Leong, PhD MS, Derek S Sim, PhD, Liang Tang, PhD, Elena Ho, Jim Wu, Katalin Zsofia Kauser, PhD MD DSc, Babu Subramanyam
Journal: Blood
Blood (2014) 124 (21): 1471.
https://doi.org/10.1182/blood.V124.21.1471.1471
Published: 2014
Journal Articles

Glycopegylated Factor IX Enables Prolonged Efficacy After Subcutaneous Injection But Requires a Higher Than Expected Plasma Activity To Prevent Bleeding In Hemophilia B Mice

Derek S Sim, Alan Brooks, Cornell Mallari, Yifan Xu, Rick I Feldman, Doug Schneider, Chandra Patel, Eric Blasko, Elena Ho, Yan Su, Bing Liu, Volker Laux, John E Murphy
Journal: Blood
Blood (2013) 122 (21): 1104.
https://doi.org/10.1182/blood.V122.21.1104.1104
Published: 2013
Journal Articles

Protein Palmitoylation in Platelet Function: Role in G Protein-Mediated Platelet Activation and Platelet Recruitment into Thrombi.

Robert Flaumenhaft, MD, PhD, James R. Dilks, Derek S. Sim, PhD
Journal: Blood
Blood (2005) 106 (11): 650.
https://doi.org/10.1182/blood.V106.11.650.650
Published: 2005
Journal Articles

Protein Palmitoylation Participates in PAR1-Mediated Platelet Activation.

Derek S. Sim, PhD, Blake R. Peterson, PhD, Steffen P. Creaser, PhD, Robert Flaumenhaft, MD PhD
Journal: Blood
Blood (2004) 104 (11): 1560.
https://doi.org/10.1182/blood.V104.11.1560.1560
Published: 2004
Journal Articles

Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels

Derek S. Sim, Glenn Merrill-Skoloff, Barbara C. Furie, Bruce Furie, Robert Flaumenhaft
Journal: Blood
Blood (2004) 103 (6): 2127–2134.
https://doi.org/10.1182/blood-2003-04-1133
Published: 2004
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