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Journal Articles

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Jeffrey I. Zwicker, MD, Benjamin L. Schlechter, MD, Jack Davis Stopa, PhD, Howard A. Liebman, MD, Anita Aggarwal, PhDDO, Thomas Caughey, MD, Ken A. Bauer, MD, Nancy Kuemmerle, D.O., Ellice Y. Wong, MD, Ted Wun, MD, Marilyn Mclaughlin, MD, Maneka Puligandla, MS, Donna S Neuberg, ScD, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD

Blood (2018) 132 (Supplement 1): 985.

https://doi.org/10.1182/blood-2018-99-114946

Published: 2018

Journal Articles

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Chao Fang, PhD, Anish V. Sharda, MBBS, MPH, Lin Lin, PhD, Robert C. Flaumenhaft, MD PhD, Bruce Furie, MD

Blood (2017) 130 (Supplement 1): 442.

https://doi.org/10.1182/blood.V130.Suppl_1.442.442

Published: 2017

Journal Articles

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Jack D Stopa, PhD, Donna S. Neuberg, ScD, Maneka Puligandla, MS, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD, Jeffrey I. Zwicker, MD

Blood (2016) 128 (22): 2628.

https://doi.org/10.1182/blood.V128.22.2628.2628

Published: 2016

Journal Articles

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Chao Fang, PhD, Sheryl R. Bowley, PhD, Barbara C. Furie, PhD, Bruce Furie, MD

Blood (2016) 128 (22): 15.

https://doi.org/10.1182/blood.V128.22.15.15

Published: 2016

Journal Articles

Vascular thiol isomerases

Robert Flaumenhaft, Bruce Furie

Blood (2016) 128 (7): 893–901.

https://doi.org/10.1182/blood-2016-04-636456

Published: 2016

Journal Articles

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Ilenia Simeoni, Jonathan C. Stephens, Fengyuan Hu, Sri V. V. Deevi, Karyn Megy, Tadbir K. Bariana, Claire Lentaigne, Sol Schulman, Suthesh Sivapalaratnam, Minka J. A. Vries, Sarah K. Westbury, Daniel Greene, Sofia Papadia, Marie-Christine Alessi, Antony P. Attwood, Matthias Ballmaier, Gareth Baynam, Emilse Bermejo, Marta Bertoli, Paul F. Bray, Loredana Bury, Marco Cattaneo, Peter Collins, Louise C. Daugherty, Rémi Favier, Deborah L. French, Bruce Furie, Michael Gattens, Manuela Germeshausen, Cedric Ghevaert, Anne C. Goodeve, Jose A. Guerrero, Daniel J. Hampshire, Daniel P. Hart, Johan W. M. Heemskerk, Yvonne M. C. Henskens, Marian Hill, Nancy Hogg, Jennifer D. Jolley, Walter H. Kahr, Anne M. Kelly, Ron Kerr, Myrto Kostadima, Shinji Kunishima, Michele P. Lambert, Ri Liesner, José A. López, Rutendo P. Mapeta, Mary Mathias, Carolyn M. Millar, Amit Nathwani, Marguerite Neerman-Arbez, Alan T. Nurden, Paquita Nurden, Maha Othman, Kathelijne Peerlinck, David J. Perry, Pawan Poudel, Pieter Reitsma, Matthew T. Rondina, Peter A. Smethurst, William Stevenson, Artur Szkotak, Salih Tuna, Christel van Geet, Deborah Whitehorn, David A. Wilcox, Bin Zhang, Shoshana Revel-Vilk, Paolo Gresele, Daniel B. Bellissimo, Christopher J. Penkett, Michael A. Laffan, Andrew D. Mumford, Augusto Rendon, Keith Gomez, Kathleen Freson, Willem H. Ouwehand, Ernest Turro

Blood (2016) 127 (23): 2791–2803.

https://doi.org/10.1182/blood-2015-12-688267

Published: 2016

Includes: Supplemental data

Journal Articles

Both platelet- and endothelial cell–derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis

Freda H. Passam, Lin Lin, Srila Gopal, Jack D. Stopa, Lola Bellido-Martin, Mingdong Huang, Barbara C. Furie, Bruce Furie

Blood (2015) 125 (14): 2276–2285.

https://doi.org/10.1182/blood-2013-12-547208

Published: 2015

Includes: Supplemental data

Journal Articles

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

Anish Sharda, Sarah H. Kim, Reema Jasuja, Srila Gopal, Robert Flaumenhaft, Barbara C. Furie, Bruce Furie

Blood (2015) 125 (10): 1633–1642.

https://doi.org/10.1182/blood-2014-08-597419

Published: 2015

Journal Articles

How I treat poisoning with vitamin K antagonists

Sol Schulman, Bruce Furie

Blood (2015) 125 (3): 438–442.

https://doi.org/10.1182/blood-2014-08-597781

Published: 2015

Journal Articles

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

Pavan K Bendapudi, MD, Roelof H Bekendam, MD, Lin Lin, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 2880.

https://doi.org/10.1182/blood.V124.21.2880.2880

Published: 2014

Journal Articles

Animal Models of Arterial and Venous Thrombosis

Bruce Furie, MD, Barbara C. Furie, PhD, Robert Flaumenhaft, MD/ PhD, Jeffrey I. Zwicker, MD

Blood (2014) 124 (21): SCI-2.

https://doi.org/10.1182/blood.V124.21.SCI-2.SCI-2

Published: 2014

Journal Articles

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Roelof H Bekendam, MD, Gopal Srila, MD, Pavan K Bendapudi, MD, James R Dilks, Lin Lin, PhD, Sheryl Bowley, PhD, Jack Stopa, PhD, Mingdong Huang, PhD, Bruce Furie, MD, Kevin Croce, MD/ PhD, Robert Flaumenhaft, MD/ PhD

Blood (2014) 124 (21): 93.

https://doi.org/10.1182/blood.V124.21.93.93

Published: 2014

Journal Articles

Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS

Valerie Proulle, Richard A. Furie, Glenn Merrill-Skoloff, Barbara C. Furie, Bruce Furie

Blood (2014) 124 (4): 611–622.

https://doi.org/10.1182/blood-2014-02-554980

Published: 2014

Includes: Supplemental data

Journal Articles

Rosuvastatin Lowers Circulating Tissue Factor Antigen-Bearing Microparticles In Metastatic Breast Cancer: A Phase II, Multi-Dose, Randomized Trial (MicroSTAT Trial)

Jeffrey I. Zwicker, MD, Erica L. Mayer, MD, Federico Campigotto, MS, Julia Geddings, Herold Christina, M.D., Sheryl Bowley, Ph.D., Gerburg Wulf, MD, Gary Horowitz, MD, Donna S. Neuberg, ScD, Nigel Mackman, PhD, Bruce Furie, MD

Blood (2013) 122 (21): 579.

https://doi.org/10.1182/blood.V122.21.579.579

Published: 2013

Journal Articles

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins

Jaehyung Cho, Daniel R. Kennedy, Lin Lin, Mingdong Huang, Glenn Merrill-Skoloff, Barbara C. Furie, Bruce Furie

Blood (2012) 120 (3): 647–655.

https://doi.org/10.1182/blood-2011-08-372532

Published: 2012

Includes: Supplemental data

Journal Articles

Role of Thiol Isomerase ERp5 in Thrombus Formation

Freda H. Passam, MD, PhD, Lin Lin, PhD, Mingdong Huang, PhD, Jonathan M. Gibbins, BSc, PhD, Bruce Furie, MD, Barbara C. Furie, PhD

Blood (2011) 118 (21): 370.

https://doi.org/10.1182/blood.V118.21.370.370

Published: 2011

Journal Articles

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Reema Jasuja, Ph.D., Freda H. Passam, MD, PhD, Daniel R Kennedy, Ph.D., Sarah H Kim, Lotte van Hessem, Lin Lin, PhD, Sucharit S Joshi, MD, James R. Dilks, Bruce Furie, MD, Barbara C. Furie, PhD, Robert C. Flaumenhaft, MD, PhD

Blood (2011) 118 (21): 369.

https://doi.org/10.1182/blood.V118.21.369.369

Published: 2011

Journal Articles

β 2 -glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model

Ariela Arad, Valerie Proulle, Richard A. Furie, Barbara C. Furie, Bruce Furie

Blood (2011) 117 (12): 3453–3459.

https://doi.org/10.1182/blood-2010-08-300715

Published: 2011

Journal Articles

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

Reema Jasuja, Bruce Furie, Barbara C. Furie

Blood (2010) 116 (22): 4665–4674.

https://doi.org/10.1182/blood-2010-04-278184

Published: 2010

Includes: Supplemental data

Journal Articles

Laser-induced endothelial cell activation supports fibrin formation

Ben T. Atkinson, Reema Jasuja, Vivien M. Chen, Prathima Nandivada, Bruce Furie, Barbara C. Furie

Blood (2010) 116 (22): 4675–4683.

https://doi.org/10.1182/blood-2010-05-283986

Published: 2010

NARROW

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Vascular thiol isomerases

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Both platelet- and endothelial cell–derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

How I treat poisoning with vitamin K antagonists

ML359, a Small Molecule Inhibitor of Protein Disulfide Isomerase That Prevents Thrombus Formation and Inhibits Oxidoreductase but Not Transnitrosylase Activity

Animal Models of Arterial and Venous Thrombosis

Regulation of Protein Disulfide Isomerase By S-Nitrosylation Controls Its Function during Thrombus Formation

Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS

Rosuvastatin Lowers Circulating Tissue Factor Antigen-Bearing Microparticles In Metastatic Breast Cancer: A Phase II, Multi-Dose, Randomized Trial (MicroSTAT Trial)

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins

Role of Thiol Isomerase ERp5 in Thrombus Formation

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

β 2 -glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

Laser-induced endothelial cell activation supports fibrin formation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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