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Journal Articles

“Treatment with curative intent”: the emergence of genetic therapies for sickle cell anemia

Edward J. Benz, Jr., Leslie E. Silberstein, Julie Panepinto

Blood (2024) 143 (11): 967–970.

https://doi.org/10.1182/blood.2023021598

Published: 2024

Journal Articles

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion

Shin-Young Park, Alessandro Matte, Yookyung Jung, Jina Ryu, Wilson Babu Anand, Eun-Young Han, Min Liu, Carmine Carbone, Davide Melisi, Takashi Nagasawa, Joseph J. Locascio, Charles P. Lin, Leslie E. Silberstein, Lucia De Franceschi

Blood (2020) 135 (23): 2071–2084.

https://doi.org/10.1182/blood.2019002227

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Shin-Young Park, PhD, Alessandro Mattè, BSc,PhD, Yookyung Jung, PhD, Jina Ryu, PhD, Wilson Anand, Eun Young Anna Han, B.S., Min Liu, M.S., Carmine Carbone, Davide Melisi, Takashi Nagasawa, Charles Lin, PhD, Leslie E. Silberstein, MD, Lucia De Franceschi, MD

Blood (2019) 134 (Supplement_1): 2256.

https://doi.org/10.1182/blood-2019-123532

Published: 2019

Journal Articles

Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice

Shin-Young Park, PhD, Alessandro Mattè, PhD, Eun Young Anna Han, B.S., Min Liu, M.S., Jina Ryu, PhD, Lucia De Franceschi, MD, Leslie E. Silberstein, MD

Blood (2017) 130 (Supplement 1): 3522.

https://doi.org/10.1182/blood.V130.Suppl_1.3522.3522

Published: 2017

Journal Articles

Platelet refractoriness: it’s not the B-all and end-all

John P. Manis, Leslie E. Silberstein

Blood (2016) 127 (14): 1740–1741.

https://doi.org/10.1182/blood-2016-02-695437

Published: 2016

Journal Articles

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Marioara F. Ciuculescu, Shin-Young Park, Kimberly Canty, Ronald Mathieu, Leslie E. Silberstein, David A. Williams

Blood (2015) 125 (20): 3105–3113.

https://doi.org/10.1182/blood-2014-10-604892

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Immune Reconstitution and Preliminary Safety Analysis Of 9 Patients Treated With Somatic Gene Therapy For X-Linked Severe Combined Immunodeficiency (SCID-X1) With a Self-Inactivating Gammaretroviral Vector

Blood (2013) 122 (21): 715.

https://doi.org/10.1182/blood.V122.21.715.715

Published: 2013

Journal Articles

A mouse model of hemolytic disease of the newborn

Chance John Luckey, Leslie E. Silberstein

Blood (2013) 122 (8): 1334–1335.

https://doi.org/10.1182/blood-2013-07-512715

Published: 2013

Journal Articles

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

Giovanni Amabile, Robert S. Welner, Cesar Nombela-Arrieta, Anna Morena D'Alise, Annalisa Di Ruscio, Alexander K. Ebralidze, Yevgenya Kraytsberg, Min Ye, Olivier Kocher, Donna S. Neuberg, Konstantin Khrapko, Leslie E. Silberstein, Daniel G. Tenen

Blood (2013) 121 (8): 1255–1264.

https://doi.org/10.1182/blood-2012-06-434407

Published: 2013

Includes: Supplemental data

Journal Articles

Age Dependent Alternations In Hematopoietic Stem Cell Niches

Geqiang Li, PhD, Cesar Nombela Arrieta, PHD, Leo D. Wang, MD, PhD, Amy J. Wagers, PhD, Leslie E Silberstein, MD

Blood (2011) 118 (21): 2395.

https://doi.org/10.1182/blood.V118.21.2395.2395

Published: 2011

Journal Articles

SALL4 Is a Key Survival Factor in Acute B-Cell Lymphoblastic Leukemia

Shikiko Ueno, MD, PhD, Jiayun Lu, PhD, He Jie, PhD, Ailing Li, PhD, XiaoXian Zhang, Leslie E Silberstein, MD, Jerome Ritz, MD, Li Chai, MD

Blood (2011) 118 (21): 2428.

https://doi.org/10.1182/blood.V118.21.2428.2428

Published: 2011

Journal Articles

Hypoxic Hematopoietic Stem and Progenitor Cells Reside in Structurally Diverse Perivascular Niches in the Bone Marrow,

Cesar Nombela-Arrieta, Gregory Pivarnik, Beatrice Winkel, Brendan Harley, John E Mahoney, Jiayun Lu, MD, PhD, Alexei Protopopov, Leslie E Silberstein, MD

Blood (2011) 118 (21): 3417.

https://doi.org/10.1182/blood.V118.21.3417.3417

Published: 2011

Journal Articles

Down-Regulation of Homeobox Gene Ventx Promotes Expansion of Human Bone Marrow Hematopoietic Stem Cells (HSC)

Hong (Jenny) Gao, MD, Ph.D., Xiaoming Wu, Ph.D., Yan Sun, PH.D.&M.D., Jiayun Lu, MD, PhD, Leslie E Silberstein, MD, Zhenglun (Jerry) Zhu, MD, Ph.D.

Blood (2011) 118 (21): 1272.

https://doi.org/10.1182/blood.V118.21.1272.1272

Published: 2011

Journal Articles

FAK Regulates Progenitor B Cell Growth, Localization and Retention in Bone Marrow Microenvironments

Shin-Young Park, Peter Wolfram, John Manis, Hilary Beggs, Cesar Nombela-Arrieta, Gregory Pivarnik, Leslie E Silberstein, MD

Blood (2011) 118 (21): 1119.

https://doi.org/10.1182/blood.V118.21.1119.1119

Published: 2011

Journal Articles

Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model

Yitang Li, Amit Prasad, Yonghui Jia, Saurabh Ghosh Roy, Fabien Loison, Subhanjan Mondal, Paulina Kocjan, Leslie E. Silberstein, Sheng Ding, Hongbo R. Luo

Blood (2011) 117 (24): 6702–6713.

https://doi.org/10.1182/blood-2010-09-309864

Published: 2011

Includes: Supplemental data

Journal Articles

Quantitative Imaging of Femoral Bone Marrow Microenvironments Reveals a Heterogenous Distribution of Hematopoietic Stem and Progenitor Cells.

Cesar Nombela-Arrieta, Brendan Harley, Gregory Pivarnik, John E Mahoney, Elena Levantini, Alexei Protopopov, Daniel G. Tenen, MD, Leslie E. Silberstein, MD

Blood (2009) 114 (22): 1455.

https://doi.org/10.1182/blood.V114.22.1455.1455

Published: 2009

Journal Articles

Deletion of Fak in Hematopoietic Stem Cells Leads to Enhanced Engraftment.

Jiayun Lu, Cesar Nombela-Arrieta, Shin-Young Park, Yi Le, Li Chai, Leslie E. Silberstein

Blood (2008) 112 (11): 1407.

https://doi.org/10.1182/blood.V112.11.1407.1407

Published: 2008

Journal Articles

Spatial Analysis of Hematopoietic Stem and Progenitor Cells in the Bone Marrow

Cesar Nombela-Arrieta, Brendan Harley, Elena Levantini, John E Mahoney, Gregory Pivarnik, Alexei Protopopov, Daniel G. Tenen, Leslie E. Silberstein, MD

Blood (2008) 112 (11): 3570.

https://doi.org/10.1182/blood.V112.11.3570.3570

Published: 2008

Journal Articles

Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment.

Trista E. North, PhD, Wolfram Goessling, MD, PhD, Myriam Armant, PhD, Grace S. Kao, MD, Leslie E. Silberstein, MD, Jerome Ritz, MD, Leonard I. Zon, MD

Blood (2007) 110 (11): 1190.

https://doi.org/10.1182/blood.V110.11.1190.1190

Published: 2007

Journal Articles

Focal Adhesion Kinase (FAK) Is Required for CXCL12-Induced Dhemotaxis and Adhesion to VCAM-1 in B Lymphocytes and Hematopoietic Stem/Progenitor Cells.

Leslie E. Silberstein, MD, Derek Dykxhoorn, Yi Le, Marek Honczarenko, M.D, PhD, Judy Lieberman, M.D., PhD, Aleksandra Glodek, DMD

Blood (2006) 108 (11): 1325.

https://doi.org/10.1182/blood.V108.11.1325.1325

Published: 2006

NARROW

“Treatment with curative intent”: the emergence of genetic therapies for sickle cell anemia

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversed by blood transfusion

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Arteriolar Neovasculogenesis and Sinusoidal Collapse Are Pathologic Features of the Hematopoietic Stem Cell Niche in Sickle Cell Disease (SCD) Mice

Platelet refractoriness: it’s not the B-all and end-all

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Immune Reconstitution and Preliminary Safety Analysis Of 9 Patients Treated With Somatic Gene Therapy For X-Linked Severe Combined Immunodeficiency (SCID-X1) With a Self-Inactivating Gammaretroviral Vector

A mouse model of hemolytic disease of the newborn

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

Age Dependent Alternations In Hematopoietic Stem Cell Niches

SALL4 Is a Key Survival Factor in Acute B-Cell Lymphoblastic Leukemia

Hypoxic Hematopoietic Stem and Progenitor Cells Reside in Structurally Diverse Perivascular Niches in the Bone Marrow,

Down-Regulation of Homeobox Gene Ventx Promotes Expansion of Human Bone Marrow Hematopoietic Stem Cells (HSC)

FAK Regulates Progenitor B Cell Growth, Localization and Retention in Bone Marrow Microenvironments

Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model

Quantitative Imaging of Femoral Bone Marrow Microenvironments Reveals a Heterogenous Distribution of Hematopoietic Stem and Progenitor Cells.

Deletion of Fak in Hematopoietic Stem Cells Leads to Enhanced Engraftment.

Spatial Analysis of Hematopoietic Stem and Progenitor Cells in the Bone Marrow

Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment.

Focal Adhesion Kinase (FAK) Is Required for CXCL12-Induced Dhemotaxis and Adhesion to VCAM-1 in B Lymphocytes and Hematopoietic Stem/Progenitor Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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