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Journal Articles

Optimizing Immunoglobulin Replacement Therapy for Patients with B-Cell Malignancies and Hypogammaglobulinemia: The Investigator-Initiated, International, Randomized Phase II/III Rational Platform Trial, and the Rationalise (STOP IgRT) Domain

Erica M. Wood, Khai Li Chai, John Reynolds, Jennifer Griffiths, Brendan Beaton, Jeannie Callum, Kyle R Crassini, Philip J Crispin, Laura Fanning, Michael Gilbertson, Andrew P Grigg, Eliza A Hawkes, C. Orla Morrissey, Stephen P Mulligan, Stephen S. Opat, David L Paterson, Dennis Petrie, Jason A Roberts, Elizabeth G Ryan, Andrew Spencer, Simon J Stanworth, Le Thi Phuong Thao, Judith Trotman, Neil A Waters, Robert Weinkove, Zoe K McQuilten
Journal: Blood
Blood (2023) 142 (Supplement 1): 1295.
https://doi.org/10.1182/blood-2023-181541
Published: 2023
Journal Articles

Genome-Wide Methylation Sensitive Elements Demarcate Targetable Regulatory Elements for Controllable Gene Activation

Yanjing Vera Liu, Jeremiah Suryatenggara, Hannan Wong, Jing Ping Tang, Hong Kee Tan, Junsu Kwon, Qiling Zhou, Simone Ummarino, Alexander Ebralidze, John G. Doench, Li Chai, Touati Benoukraf, Devendra Hiwase, Daniel Thomas, Annalisa Di Ruscio, Daniel G. Tenen, Mahmoud Adel Bassal
Journal: Blood
Blood (2023) 142 (Supplement 1): 3647.
https://doi.org/10.1182/blood-2023-182715
Published: 2023
Journal Articles

Targeting the Oncofetal Transcription Factor Protein SALL4 in Cancer By a Non-IMiD Degrader

Kim Anh L. Vu, Kalpana Kumari, Bee Hui Liu, Chong Gao, Feng Li, Jing Ping Tang, Danilo Maddalo, Xi Tian, Miao Liu, Mahmoud Adel Bassal, Shiva Moein, Viktoriia Iakovleva, Justin L. Tan, Alicia J. Stein, Qiling Zhou, Patrick D. Fischer, Logan H. Sigua, Jun Qi, Haribabu Arthanari, Daniel G. Tenen, Li Chai
Journal: Blood
Blood (2023) 142 (Supplement 1): 7144.
https://doi.org/10.1182/blood-2023-184502
Published: 2023
Journal Articles

Ultrasensitive Detection of SALL4 Oncoproteins in Peripheral Blood and Bone Marrow Aspirate: Companion Diagnostics and Therapeutic Monitoring

Sanjana Shah, Jun Liu, Yasmeen Senussi, Arek Melkonian, James Nuhfer, Scott Lovitch, Neal Lindeman, Annette S. Kim, David R. Walt, Li Chai
Journal: Blood
Blood (2023) 142 (Supplement 1): 6049.
https://doi.org/10.1182/blood-2023-187876
Published: 2023
Journal Articles

Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression

Ryan P. Jajosky, Kashyap R. Patel, Jerry William L. Allen, Patricia E. Zerra, Satheesh Chonat, Diyoly Ayona, Cheryl L. Maier, Dominique Morais, Shang-Chuen Wu, C. John Luckey, Stephanie C. Eisenbarth, John D. Roback, Ross M. Fasano, Cassandra D. Josephson, John P. Manis, Li Chai, Jeanne E. Hendrickson, Krystalyn E. Hudson, Connie M. Arthur, Sean R. Stowell
Journal: Blood
Blood (2023) 142 (12): 1082–1098.
https://doi.org/10.1182/blood.2022018591
Published: 2023
Includes: Supplemental data
Journal Articles

Antibody-Mediated Antigen Loss Can Switch an Augmented Immune Response to Antibody-Mediated Immunosuppression

Ryan Philip Jajosky, Jerry W. Allen, Patricia E Zerra, Cheryl L Maier, Satheesh Chonat, Chance John Luckey, John D. Roback, Ross M. Fasano, Cassandra D. Josephson, John P Manis, Li Chai, Jeanne E. Hendrickson, Krystalyn E Hudson, Connie M. Arthur, Sean R. Stowell
Journal: Blood
Blood (2022) 140 (Supplement 1): 73–74.
https://doi.org/10.1182/blood-2022-170081
Published: 2022
Journal Articles

Variation in Use of Immunoglobulin and Impact on Survival in Multiple Myeloma: A Report from the Australian and New Zealand Myeloma and Related Diseases Registry (MRDR)

Khai Li Chai, Cameron Wellard, Elizabeth M. Moore, Bradley Augustson, Akshay Bapat, Hilary Anne Blacklock, Rachel Elizabeth Cooke, Cecily Forsyth, Nada Hamad, Simon J Harrison, Phoebe Joy Ho, Jay Hocking, Ian H. Kerridge, Tracy King, Georgia J McCaughan, Peter Mollee, Orla Morrissey, Nicholas E. Murphy, Hang Quach, Xuan Ni Tan, Kimberly Wong, Andrew Spencer, Erica M. Wood, Zoe McQuilten
Journal: Blood
Blood (2021) 138 (Supplement 1): 4757.
https://doi.org/10.1182/blood-2021-147622
Published: 2021
Journal Articles

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Bon Q. Trinh, Simone Ummarino, Yanzhou Zhang, Alexander K. Ebralidze, Mahmoud A. Bassal, Tuan M. Nguyen, Gerwin Heller, Rory Coffey, Danielle E. Tenen, Emiel van der Kouwe, Emiliano Fabiani, Carmelo Gurnari, Chan-Shuo Wu, Vladimir Espinosa Angarica, Henry Yang, Sisi Chen, Hong Zhang, Abby R. Thurm, Francisco Marchi, Elena Levantini, Philipp B. Staber, Pu Zhang, Maria Teresa Voso, Pier Paolo Pandolfi, Susumu S. Kobayashi, Li Chai, Annalisa Di Ruscio, Daniel G. Tenen
Journal: Blood
Blood (2021) 138 (15): 1331–1344.
https://doi.org/10.1182/blood.2020007920
Published: 2021
Includes: Supplemental data
Journal Articles

Oncofetal Protein SALL4 Is Highly Expressed in Myelodysplastic Syndrome Alongside with NAT10 and P53

Hiro Tatetsu, MD, Miho Watanabe, MD, Emily F Mason, MD PhD, Scott B Lovitch, MDPhD, Kenji Tokunaga, MD, Eisaku Iwanaga, MD, Masao Matsuoka, MDPhD, Daniel G. Tenen, MD, Li Chai, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-134533
Published: 2020
Journal Articles

Improved Survival of Older Patients with Mantle Cell Lymphoma (MCL) with Front-Line Cytarabine-Based Immunochemotherapy

Sumita Ratnasingam, MBBS, Michael Gilbertson, Zoe McQuilten, MBBS, Kay T Htun, George Grigoriadis, MBBS, PhD BSc, Swe Myo Htet, MBBS, Philip Campbell, MBBS, FRACP, FRCPA, Khai Li Chai, MBBS, Hang Quach, MBBS (Hons), FRACP, FRCPA, MD, Sushrut S. Patil, FRACP, FRCPA, Jake Shortt, MD, Stephen Opat, MD
Journal: Blood
Blood (2016) 128 (22): 2965.
https://doi.org/10.1182/blood.V128.22.2965.2965
Published: 2016
Journal Articles

Early Bortezomib Failure Predicts Shorter PFS: a Retrospective Analysis from 4 Victorian Centres

Krystal Bergin, Thomas E Lew, Annie W.S. Chow, Paul Kopanidis, Hui Yin Lim, Kah Lok Chan, Khai-Li Chai, Chong Chyn Chua, John Reynolds, Andrew Spencer
Journal: Blood
Blood (2016) 128 (22): 5708.
https://doi.org/10.1182/blood.V128.22.5708.5708
Published: 2016
Journal Articles

Mechanisms of MEF2C-Dependent Transcription in Lymphoid Differentiation

Nikki R. Kong, PhD, Li Chai, MD, Astar Winoto, PhD, Robert Tjian, PhD
Journal: Blood
Blood (2014) 124 (21): 4341.
https://doi.org/10.1182/blood.V124.21.4341.4341
Published: 2014
Journal Articles

SALL4 Is a Key Factor in HDAC Inhibitor Mediated Ex Vivo Expansion of Human Peripheral Blood Mobilized Stem/Progenitor CD34+CD90+ Cells

Hiro Tatetsu, MD PhD, Fei Wang, Chong Gao, MD PhD, Shikiko Ueno, MD PhD, Xi Tian, BS, Myriam Armant, PhD, Alex Federation, Jun Qi, PhD, James E. Bradner, Daniel G. Tenen, MD, Li Chai, MD
Journal: Blood
Blood (2014) 124 (21): 1566.
https://doi.org/10.1182/blood.V124.21.1566.1566
Published: 2014
Journal Articles

Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

Chong Gao, Todor Dimitrov, Kol Jia Yong, Hiro Tatetsu, Ha-won Jeong, Hongbo R. Luo, James E. Bradner, Daniel G. Tenen, Li Chai
Journal: Blood
Blood (2013) 121 (8): 1413–1421.
https://doi.org/10.1182/blood-2012-04-424275
Published: 2013
Includes: Supplemental data
Journal Articles

A Novel Approach in Expanding CD34+CD90+ and CD34+CD38-CD90+ Cells Associated with Enhanced in Vivo Repopulating potential.

Hiro Tatetsu, MD, PhD, Chong Gao, MD, PhD, Shikiko Ueno, MD, PhD, Daniel G Tenen, MD, Li Chai, MD
Journal: Blood
Blood (2012) 120 (21): 2337.
https://doi.org/10.1182/blood.V120.21.2337.2337
Published: 2012
Journal Articles

SALL4 Is a Key Survival Factor in Acute B-Cell Lymphoblastic Leukemia

Shikiko Ueno, MD, PhD, Jiayun Lu, PhD, He Jie, PhD, Ailing Li, PhD, XiaoXian Zhang, Leslie E Silberstein, MD, Jerome Ritz, MD, Li Chai, MD
Journal: Blood
Blood (2011) 118 (21): 2428.
https://doi.org/10.1182/blood.V118.21.2428.2428
Published: 2011
Journal Articles

Sall4, a Stem Cell Factor, Promotes Chemoresistance by Regulates the Side Population Cell Phenotype.

Ha-Won Jeong, Wei Cui, Ye Guo, Youyang Yang, Jiayun Lu, MD, PhD, Chong Gao, MD, PhD, Li Chai
Journal: Blood
Blood (2009) 114 (22): 3093.
https://doi.org/10.1182/blood.V114.22.3093.3093
Published: 2009
Journal Articles

Deletion of Fak in Hematopoietic Stem Cells Leads to Enhanced Engraftment.

Jiayun Lu, Cesar Nombela-Arrieta, Shin-Young Park, Yi Le, Li Chai, Leslie E. Silberstein
Journal: Blood
Blood (2008) 112 (11): 1407.
https://doi.org/10.1182/blood.V112.11.1407.1407
Published: 2008
Journal Articles

SALL4 is a key regulator of survival and apoptosis in human leukemic cells

Jianchang Yang, Li Chai, Chong Gao, Taylor C. Fowles, Zaida Alipio, Hien Dang, Dan Xu, Louis M. Fink, David C. Ward, Yupo Ma
Journal: Blood
Blood (2008) 112 (3): 805–813.
https://doi.org/10.1182/blood-2007-11-126326
Published: 2008
Includes: Supplemental data
Journal Articles

SALL4-Dependent Signaling Networks Are Required for Survival of Leukemia Cells.

Jianchang Yang, MD, Li Chai, MD, Taylor Fowles, BS, Zaida Alipio, BS, Chong Gao, MD, Louis Fink, MD, Yupo Ma, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2635.
https://doi.org/10.1182/blood.V110.11.2635.2635
Published: 2007