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Elke De Bruyne, PhD
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Journal Articles

The Exosomal Transfer of Acid Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma

Inge Oudaert, MSc, Sylvia Faict, MSc, Ludovic D'Auria, PhD, Jonas Dehairs, PhD, Ken Maes, Philip Vlummens, MD, Lotte Jacobs, BSc, Kim De Veirman, Elke De Bruyne, PhD, Karel Fostier, MD, Isabelle Vande Broek, MD PhD, Rik Schots, Karin Vanderkerken, PhD, Johannes V. Swinnen, PhD, Eline Menu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3058.
https://doi.org/10.1182/blood-2019-122857
Published: 2019
Journal Articles

Receptor Tyrosine Kinase AXL: A Potential Strategy to Counter Immune Suppression and Dormancy in Multiple Myeloma

Kim De Veirman, Siyang Yan, Ken Maes, Nathan De Beule, MD, Sylvia Faict, MSc, Elke De Bruyne, PhD, Eline Menu, PhD, Karin Vanderkerken, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4335.
https://doi.org/10.1182/blood-2019-126834
Published: 2019
Journal Articles

MCL1 Inhibitors in Multiple Myeloma

Karin Vanderkerken, PhD, Kim De Veirman, Ken Maes, Eline Menu, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-12.
https://doi.org/10.1182/blood-2019-121104
Published: 2019
Journal Articles

Exosomes Play a Key Role in Multiple Myeloma Bone Disease and Tumor Development

Sylvia Faict, MD, Josephine Muller, PhD, Kim De Veirman, PhD, Ken Maes, Elke De Bruyne, PhD, Rik Schots, Jo Caers, MD PhD, Karin Vanderkerken, PhD, Eline Menu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4484.
https://doi.org/10.1182/blood-2018-99-112428
Published: 2018
Journal Articles

Histone Methyltransferases G9a and GLP; Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma Treatment

Eva De Smedt, Julie Devin, Hui Liu, Anke Maes, Ken Maes, Kim De Veirman, Eline Menu, PhD, Karin Vanderkerken, PhD, Jerome Moreaux, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4356.
https://doi.org/10.1182/blood.V130.Suppl_1.4356.4356
Published: 2017
Journal Articles

The Anaphase Promoting Complex/Cyclosome: A New Promising Target in Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma

Anke Maes, Eva De Smedt, Kim De Veirman, Ken Maes, Eline Menu, PhD, Els Van Valckenborgh, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2757.
https://doi.org/10.1182/blood.V130.Suppl_1.2757.2757
Published: 2017
Journal Articles

Kinome Expression Profiling in Multiple Myeloma Identifies New Therapeutic Targets

Hugues de Boussac, PhD, Angelique Bruyer, Nicolas Robert, Anke Maes, Laure Vincent, Anja Seckinger, Guillaume Cartron, Dirk Hose, MD, Elke De Bruyne, PhD, Alboukadel Kassambara, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1766.
https://doi.org/10.1182/blood.V130.Suppl_1.1766.1766
Published: 2017
Journal Articles

SET8 Is a Potential Therapeutic Target in MM

Herviou Laurie, Fanny Izard, Elke De Bruyne, PhD, Eva Desmedt, Anqi Ma, PhD, Jian Jin, PhD, Karin Vanderkerken, PhD, Eric Julien, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 4435.
https://doi.org/10.1182/blood.V128.22.4435.4435
Published: 2016
Journal Articles

RAS Association Domain Family Member 4 (RASSF4): A New Potent Tumor Suppressor in Multiple Myeloma

Eva De Smedt, Ken Maes, PhD, Stefan Verhulst, Hui Lui, Alboukadel Kassambara, PhD, Anke Maes, Dirk Hose, MD, Karine Breckpot, Jerome Moreaux, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2016) 128 (22): 2057.
https://doi.org/10.1182/blood.V128.22.2057.2057
Published: 2016
Journal Articles

The Crosstalk Between Leptin Receptor Activation and iNKT Mediated Anti-Tumor Immunity in Multiple Myeloma

Mérédis Favreau, PhDstudent, Eline Menu, PhD, Karin Vanderkerken, PhD, Sylvia Faict, MD, Ken Maes, PhD, Els Van Valckenborgh, PhD, Elke De Bruyne, PhD, Srinath Govindarajan, PhDstudent, Michael Drennan, PhD, Xavier Leleu, Lennart Zabeau, PhD, Jan Tavernier, PhD, Koen Venken, PhD, Dirk Elewaut, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2075.
https://doi.org/10.1182/blood.V128.22.2075.2075
Published: 2016
Journal Articles

Targeting S100A9 Interactions in the Multiple Myeloma Bone Marrow Environment Reduces Angiogenesis and Tumor Growth

Kim De Veirman, PhD, Els Van Valckenborgh, PhD, Nathan De Beule, MD, Hendrik De Raeve, Ken Maes, PhD, Elke De Bruyne, PhD, Eline Menu, PhD, Karin Vanderkerken, PhD
Journal: Blood
Blood (2016) 128 (22): 3248.
https://doi.org/10.1182/blood.V128.22.3248.3248
Published: 2016
Journal Articles

Targeting the Anaphase Promoting Complex/Cyclosome (APC/C) in Multiple Myeloma

Susanne Lub, Anke Maes, Ken Maes, Kim De Veirman, Xavier Leleu, MD PhD, Eline Menu, PhD, Elke De Bruyne, PhD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2014) 124 (21): 2097.
https://doi.org/10.1182/blood.V124.21.2097.2097
Published: 2014
Journal Articles

Myeloid Derived Suppressor Cell Mediated AMPK Activation Regulates Multiple Myeloma Cell Survival

Kim De Veirman, Jo A. Van Ginderachter, Ivan Van Riet, Nathan De Beule, Susanne Lub, Eline Menu, PhD, Elke De Bruyne, PhD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2014) 124 (21): 2009.
https://doi.org/10.1182/blood.V124.21.2009.2009
Published: 2014
Journal Articles

The in vivo Transcriptional Response Towards Epigenetic Modulating Agents in Multiple Myeloma

Ken Maes, Eva De Smedt, Kassambara Alboukadel, PhD, Dirk Hose, MD PhD, Anja Seckinger, MD PhD, Els Van Valckenborgh, PhD, Eline Menu, PhD, Bernard Klein, MD PhD, Karin Vanderkerken, PhD, Jerome Moreaux, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2014) 124 (21): 3375.
https://doi.org/10.1182/blood.V124.21.3375.3375
Published: 2014
Journal Articles

Bone Marrow Stromal Cell-Derived Exosomes Facilitate Multiple Myeloma Cell Survival Through Inhibition Of The JNK Pathway

Jinheng Wang, An Hendrix, PhD, Elke De Bruyne, PhD, Els Van Valckenborgh, PhD, Eddy Himpe, Nathan De Beule, MD, Olivier De Wever, PhD, Karin Vanderkerken, Eline Menu, PhD
Journal: Blood
Blood (2013) 122 (21): 679.
https://doi.org/10.1182/blood.V122.21.679.679
Published: 2013
Journal Articles

The DNA Methyltransferase Inhibitor Decitabine Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Multiple Myeloma

Ken Maes, Miguel Lemaire, Jordan Gauthier, Hendrik De Raeve, Eline Menu, PhD, Els Van Valckenborgh, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 1833.
https://doi.org/10.1182/blood.V120.21.1833.1833
Published: 2012
Journal Articles

Preclinical Evaluation of Invariant Natural Killer T-Cells in the 5T33 Multiple Myeloma Model

Haneen Nur, Sandrine Aspeslagh, PhD, Els Van Valckenborgh, PhD, Elke De Bruyne, PhD, Dirk Elewaut, MD, PhD, Karin Vanderkerken, PhD, Eline Menu, PhD
Journal: Blood
Blood (2012) 120 (21): 938.
https://doi.org/10.1182/blood.V120.21.938.938
Published: 2012
Journal Articles

Combination of the IGF-1 Receptor Inhibitor Picropodophylin and the BH3 Mimetic ABT-737 Has Synergistic Anti-Myeloma Activity

Liesbeth Bieghs, Ken Maes, Els Van Valckenborgh, PhD, Eline Menu, PhD, Hans Erik Johnsen, Mette Nyegaard, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 4010.
https://doi.org/10.1182/blood.V120.21.4010.4010
Published: 2012
Journal Articles

Dll1/Notch Interaction Contributes to a Decreased Sensitivity of Myeloma Cells to Bortezomib

Dehui Xu, Jingsong Hu, Elke De Bruyne, PhD, Eline Menu, PhD, Rik Schots, MD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2012) 120 (21): 1840.
https://doi.org/10.1182/blood.V120.21.1840.1840
Published: 2012