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Els Van Valckenborgh
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Journal Articles

The Anaphase Promoting Complex/Cyclosome: A New Promising Target in Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma

Anke Maes, Eva De Smedt, Kim De Veirman, Ken Maes, Eline Menu, PhD, Els Van Valckenborgh, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2757.
https://doi.org/10.1182/blood.V130.Suppl_1.2757.2757
Published: 2017
Journal Articles

Targeting S100A9 Interactions in the Multiple Myeloma Bone Marrow Environment Reduces Angiogenesis and Tumor Growth

Kim De Veirman, PhD, Els Van Valckenborgh, PhD, Nathan De Beule, MD, Hendrik De Raeve, Ken Maes, PhD, Elke De Bruyne, PhD, Eline Menu, PhD, Karin Vanderkerken, PhD
Journal: Blood
Blood (2016) 128 (22): 3248.
https://doi.org/10.1182/blood.V128.22.3248.3248
Published: 2016
Journal Articles

The Crosstalk Between Leptin Receptor Activation and iNKT Mediated Anti-Tumor Immunity in Multiple Myeloma

Mérédis Favreau, PhDstudent, Eline Menu, PhD, Karin Vanderkerken, PhD, Sylvia Faict, MD, Ken Maes, PhD, Els Van Valckenborgh, PhD, Elke De Bruyne, PhD, Srinath Govindarajan, PhDstudent, Michael Drennan, PhD, Xavier Leleu, Lennart Zabeau, PhD, Jan Tavernier, PhD, Koen Venken, PhD, Dirk Elewaut, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2075.
https://doi.org/10.1182/blood.V128.22.2075.2075
Published: 2016
Journal Articles

Targeting the Anaphase Promoting Complex/Cyclosome (APC/C) in Multiple Myeloma

Susanne Lub, Anke Maes, Ken Maes, Kim De Veirman, Xavier Leleu, MD PhD, Eline Menu, PhD, Elke De Bruyne, PhD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2014) 124 (21): 2097.
https://doi.org/10.1182/blood.V124.21.2097.2097
Published: 2014
Journal Articles

Myeloid Derived Suppressor Cell Mediated AMPK Activation Regulates Multiple Myeloma Cell Survival

Kim De Veirman, Jo A. Van Ginderachter, Ivan Van Riet, Nathan De Beule, Susanne Lub, Eline Menu, PhD, Elke De Bruyne, PhD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2014) 124 (21): 2009.
https://doi.org/10.1182/blood.V124.21.2009.2009
Published: 2014
Journal Articles

The in vivo Transcriptional Response Towards Epigenetic Modulating Agents in Multiple Myeloma

Ken Maes, Eva De Smedt, Kassambara Alboukadel, PhD, Dirk Hose, MD PhD, Anja Seckinger, MD PhD, Els Van Valckenborgh, PhD, Eline Menu, PhD, Bernard Klein, MD PhD, Karin Vanderkerken, PhD, Jerome Moreaux, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2014) 124 (21): 3375.
https://doi.org/10.1182/blood.V124.21.3375.3375
Published: 2014
Journal Articles

Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells

Jinheng Wang, An Hendrix, Sophie Hernot, Miguel Lemaire, Elke De Bruyne, Els Van Valckenborgh, Tony Lahoutte, Olivier De Wever, Karin Vanderkerken, Eline Menu
Journal: Blood
Blood (2014) 124 (4): 555–566.
https://doi.org/10.1182/blood-2014-03-562439
Published: 2014
Includes: Supplemental data
Journal Articles

Bone Marrow Stromal Cell-Derived Exosomes Facilitate Multiple Myeloma Cell Survival Through Inhibition Of The JNK Pathway

Jinheng Wang, An Hendrix, PhD, Elke De Bruyne, PhD, Els Van Valckenborgh, PhD, Eddy Himpe, Nathan De Beule, MD, Olivier De Wever, PhD, Karin Vanderkerken, Eline Menu, PhD
Journal: Blood
Blood (2013) 122 (21): 679.
https://doi.org/10.1182/blood.V122.21.679.679
Published: 2013
Journal Articles

Dll1/Notch Interaction Contributes to a Decreased Sensitivity of Myeloma Cells to Bortezomib

Dehui Xu, Jingsong Hu, Elke De Bruyne, PhD, Eline Menu, PhD, Rik Schots, MD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD
Journal: Blood
Blood (2012) 120 (21): 1840.
https://doi.org/10.1182/blood.V120.21.1840.1840
Published: 2012
Journal Articles

The DNA Methyltransferase Inhibitor Decitabine Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Multiple Myeloma

Ken Maes, Miguel Lemaire, Jordan Gauthier, Hendrik De Raeve, Eline Menu, PhD, Els Van Valckenborgh, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 1833.
https://doi.org/10.1182/blood.V120.21.1833.1833
Published: 2012
Journal Articles

Combination of the IGF-1 Receptor Inhibitor Picropodophylin and the BH3 Mimetic ABT-737 Has Synergistic Anti-Myeloma Activity

Liesbeth Bieghs, Ken Maes, Els Van Valckenborgh, PhD, Eline Menu, PhD, Hans Erik Johnsen, Mette Nyegaard, PhD, Helena Jernberg Wiklund, PhD, Karin Vanderkerken, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2012) 120 (21): 4010.
https://doi.org/10.1182/blood.V120.21.4010.4010
Published: 2012
Journal Articles

Preclinical Evaluation of Invariant Natural Killer T-Cells in the 5T33 Multiple Myeloma Model

Haneen Nur, Sandrine Aspeslagh, PhD, Els Van Valckenborgh, PhD, Elke De Bruyne, PhD, Dirk Elewaut, MD, PhD, Karin Vanderkerken, PhD, Eline Menu, PhD
Journal: Blood
Blood (2012) 120 (21): 938.
https://doi.org/10.1182/blood.V120.21.938.938
Published: 2012
Journal Articles

Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition

Jinsong Hu, Nana Dang, Eline Menu, Elke De Bryune, Dehui Xu, Ben Van Camp, Els Van Valckenborgh, Karin Vanderkerken
Journal: Blood
Blood (2012) 119 (3): 826–837.
https://doi.org/10.1182/blood-2011-07-366492
Published: 2012
Includes: Supplemental data
Journal Articles

Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

Brief Report
Jinsong Hu, Damian R. Handisides, Els Van Valckenborgh, Hendrik De Raeve, Eline Menu, Isabelle Vande Broek, Qian Liu, Jessica D. Sun, Ben Van Camp, Charles P. Hart, Karin Vanderkerken
Journal: Blood
Blood (2010) 116 (9): 1524–1527.
https://doi.org/10.1182/blood-2010-02-269126
Published: 2010
Includes: Supplemental data
Journal Articles

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms

Elke De Bruyne, Tomas J. Bos, Frans Schuit, Els Van Valckenborgh, Eline Menu, Lieven Thorrez, Peter Atadja, Helena Jernberg-Wiklund, Karin Vanderkerken
Journal: Blood
Blood (2010) 115 (12): 2430–2440.
https://doi.org/10.1182/blood-2009-07-232801
Published: 2010
Includes: Supplemental data
Journal Articles

Hypoxia Activated Prodrug TH-302 for the Treatment of Multiple Myeloma.

Jinsong Hu, Damian R Handisides, Els Van Valckenborgh, Hendrik De Raeve, Eline Menu, Isabelle Vande Broek, Qian Liu, Jessica D Sun, Ben Van Camp, Charles Hart, Karin Vanderkerken
Journal: Blood
Blood (2009) 114 (22): 3838.
https://doi.org/10.1182/blood.V114.22.3838.3838
Published: 2009
Journal Articles

Myeloid-Derived Suppressor Cells in Multiple Myeloma.

Els Van Valckenborgh, Jo Van Ginderachter, Kiavash Movahedi, Eline Menu, Karin Vanderkerken
Journal: Blood
Blood (2009) 114 (22): 2794.
https://doi.org/10.1182/blood.V114.22.2794.2794
Published: 2009
Journal Articles

Decreased Thymosin Beta 4 Expression Results in Poor Prognosis and Decreased Survival in Multiple Myeloma.

Jo Caers, Dirk Hose, Ine Kuipers, Tomas Jan Bos, Els Van Valckenborgh, Eline Menu, Elke De Bruyne, Hartmut Goldschmidt, Ben Van Camp, Bernard Klein, Karin Vanderkerken
Journal: Blood
Blood (2008) 112 (11): 1703.
https://doi.org/10.1182/blood.V112.11.1703.1703
Published: 2008
Journal Articles

Regulation of Bim Expression by IGF-1 in the 5T33MM Murine Model for Multiple Myeloma.

Elke De Bruyne, Tomas Bos, Sarah Deleu, Peter Atadja, PhD, Eline Menu, PhD, Els Van Valckenborgh, PhD, Ben Van Camp, MD, PhD, Karin Vanderkerken, PhD
Journal: Blood
Blood (2007) 110 (11): 3512.
https://doi.org/10.1182/blood.V110.11.3512.3512
Published: 2007