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Journal Articles

Association between Insufficient Interleukin-6 (IL-6) Inhibition and Worsening Outcomes in COVID-19 and Idiopathic Multicentric Castleman Disease (iMCD), and a Mathematical Model to Predict Optimal Dosing to Completely Block IL-6 Activity

Jean-Francois Rossi, Hao-Chun Chiang, Zhao-Yang Lu, Kalle Levon, Frits van Rhee, Karan Kanhai, David C Fajgenbaum, Bernard Klein
Journal: Blood
Blood (2021) 138 (Supplement 1): 4004.
https://doi.org/10.1182/blood-2021-150433
Published: 2021
Journal Articles

CD200 Is a Potent New Growth Factor in Multiple Myeloma through IGF-1R Interaction

Angélique Bruyer, MSc, Nicolas Robert, Stéphanie Boireau, Christophe Hirtz, Laurent Tiers, Laure Vincent, Guillaume Cartron, Dirk Hose, MD, Anja Seckinger, Bernard Klein, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3045.
https://doi.org/10.1182/blood.V130.Suppl_1.3045.3045
Published: 2017
Journal Articles

Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis

Anja Seckinger, MD, Anna Jauch, PhD, Martina Emde, Susanne Beck, Marcel Mohr, Martin Granzow, PhD, Thomas Hielscher, Thierry Rème, MD, Reinhard Schnettler, Nassim Fard, Katrin Hinderhofer, Paul Theodor Pyl, Wolfgang Huber, PhD, Vladimir Benes, PhD, Anna Marciniak-Czochra, Véronique Pantesco, Anthony D. Ho, MD, Bernard Klein, Jens Hillengass, MD, Dirk Hose, MD
Journal: Blood
Blood (2016) 128 (22): 235.
https://doi.org/10.1182/blood.V128.22.235.235
Published: 2016
Journal Articles

Identification of a Gene Signature Associated to Treatment Response to Palbociclib in Multiple Myeloma

Angelique Bruyer, Alboukadel Kassambara, PhD, Paul Anziani, Donia El Bahlagui, Nicolas Robert, Laure Vincent, MD, Bernard Klein, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 5666.
https://doi.org/10.1182/blood.V128.22.5666.5666
Published: 2016
Journal Articles

On the Redox Profile of B- Cell Terminal Differentiation and Multiple Myeloma: New Insights and Therapeutic Opportunities

Wafa Hassen, PhD, Alboukadel Kassambara, PhD, Michel Jourdan, Stephanie Boireau, PhD, Anja Seckinger, MD, Dirk Hose, Yubin Kang, MD, Bernard Klein, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 5644.
https://doi.org/10.1182/blood.V128.22.5644.5644
Published: 2016
Journal Articles

A Small Molecule That Selectively Targets BLM Helicase Has a Therapeutic Interest in Multiple Myeloma

Elena Viziteu, Yea Lih Lin, Laure Vincent, MD, Anja Seckinger, MD, Dirk Hose, Angelos Constantinou, Bernard Klein, Philippe Pasero, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 4433.
https://doi.org/10.1182/blood.V128.22.4433.4433
Published: 2016
Journal Articles

Patterns of Microrna in Plasma Cells: From Normal Differentiation to Multiple Myeloma

Alboukadel Kassambara, PhD, Angelique Bruyer, Michel Jourdan, Nicolas Robert, Véronique Pantesco, Olivier Elemento, PhD, Bernard Klein, Jerome Moreaux, PhD
Journal: Blood
Blood (2016) 128 (22): 2069.
https://doi.org/10.1182/blood.V128.22.2069.2069
Published: 2016
Journal Articles

Inhibition of SUV39H Methyltransferase As a Potent Therapeutic Target in Multiple Myeloma

Julie Devin, Elena Viziteu, Laurie Herviou, Anja Seckinger, MD, Grandmougin Camille, Hartmut Goldschmidt, MD, Laure Vincent, MD, Philippe Pasero, PhD, Dirk Hose, MD, Bernard Klein, PhD, Jerome Moreaux, PhD
Journal: Blood
Blood (2015) 126 (23): 1771.
https://doi.org/10.1182/blood.V126.23.1771.1771
Published: 2015
Journal Articles

The in vivo Transcriptional Response Towards Epigenetic Modulating Agents in Multiple Myeloma

Ken Maes, Eva De Smedt, Kassambara Alboukadel, PhD, Dirk Hose, MD PhD, Anja Seckinger, MD PhD, Els Van Valckenborgh, PhD, Eline Menu, PhD, Bernard Klein, MD PhD, Karin Vanderkerken, PhD, Jerome Moreaux, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2014) 124 (21): 3375.
https://doi.org/10.1182/blood.V124.21.3375.3375
Published: 2014
Journal Articles

Controlled Epstein-Barr Virus Reactivation After Allogenic Transplantation Improves Survival and Is Associated To An Expansion Of Natural Killer Cells (NK)

Sophie Auger, MD, Mattea Orsini, Patrice Ceballos, MD, Nathalie Fegueux, MD, Bernard Klein, PhD, Martin Villalba, Jean-Francois Rossi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4594.
https://doi.org/10.1182/blood.V122.21.4594.4594
Published: 2013
Journal Articles

Bone Turnover In Multiple Myeloma: Impact Of Bortezomib-Based Induction Therapy, High-Dose Melphalan, and Lenalidomide Consolidation On Osteoblast and Osteoclast Function Within The GMMG-MM5 Trial

Anja Seckinger, MD, Tobias Meißner, PhD, Uta Bertsch, MD, Hans Salwender, MD, Jan Dürig, MD, Mathias Hänel, MD, Igor W. Blau, MD, Christof Scheid, MD, Katja Weisel, MD, Bernard Klein, PhD, Hartmut Goldschmidt, MD, Dirk Hose, Dr. med. dipl.-phys.
Journal: Blood
Blood (2013) 122 (21): 1863.
https://doi.org/10.1182/blood.V122.21.1863.1863
Published: 2013
Journal Articles

Role Of RECQ1 Helicase In Multiple Myeloma Biology and Drug Resistance

Elena Viziteu, Bernard Klein, PhD, Angelique Bruyer, Dirk Hose, Dr. med. dipl.-phys., Hartmut Goldschmidt, MD, Camille Grandmougin, Jihane Basbous, Angelos Constantinou, Jerome Moreaux, PhD
Journal: Blood
Blood (2013) 122 (21): 1889.
https://doi.org/10.1182/blood.V122.21.1889.1889
Published: 2013
Journal Articles

Expression Quantitative Trait Loci Reveal Regulatory Regions Important In The Pathogenesis of Multiple Myeloma

David C Johnson, PhD, Niels Weinhold, PhD, Tobias Meissner, Dipl.-bioinf. (FH), Brian A Walker, PhD, Peter Broderick, PhD, Bowang Chen, PhD, Daniel Chubb, PhD, Per Hoffmann, PhD, Christopher P Wardell, PhD, Alexander Murison, PhD, Ni L Li, BSc, Fiona M Ross, DPhil, Jérôme Moreaux, PhD, Asta Försti, PhD, Walter Gregory, PhD, Faith E Davies, MD, Richard S Houlston, MD, PhD, Kari Hemminki, PhD, Bernard Klein, PhD, Dirk Hose, Dr. med. dipl.-phys., Hartmut Goldschmidt, MD, Gareth J Morgan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1847.
https://doi.org/10.1182/blood.V122.21.1847.1847
Published: 2013
Journal Articles

Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6

Mathias Witzens-Harig, Dirk Hose, Simone Jünger, Christina Pfirschke, Nisit Khandelwal, Ludmila Umansky, Anja Seckinger, Heinke Conrad, Bettina Brackertz, Thierry Rème, Brigitte Gueckel, Tobias Meißner, Michael Hundemer, Anthony D. Ho, Jean-Francois Rossi, Kai Neben, Helga Bernhard, Hartmut Goldschmidt, Bernard Klein, Philipp Beckhove
Journal: Blood
Blood (2013) 121 (22): 4493–4503.
https://doi.org/10.1182/blood-2012-05-429415
Published: 2013
Includes: Supplemental data
Journal Articles

Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Is Downregulated in Multiple Myeloma with Consequneces for Myeloma Cell Growth and Bone Disease

Arnold Bolomsky, Dirk Hose, MD, Martin Schreder, MD, Anja Seckinger, MD, Tobias Meißner, Bernard Klein, Daniel Heintel, Sabine Pfeifer, Heinz Ludwig, Niklas Zojer
Journal: Blood
Blood (2012) 120 (21): 3947.
https://doi.org/10.1182/blood.V120.21.3947.3947
Published: 2012
Journal Articles

Human Multiple Myeloma and Breast Cancer Cells Evade Immune Rejection Through Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6.

Mathias Witzens-Harig, MD, Dirk Hose, MD, PhD, Simone Jünger, Christina Pfirschke, Nisit Khandelwal, Anja Seckinger, MD, Heinke Conrad, Bettina Brackertz, Thierry Reme, Brigittte Gückel, Tobias Meissner, Michael Hundemer, Anthony D Ho, MD, Jean-Francois Rossi, MD, PhD, Kai Neben, MD, Helga Bernhard, MD, Hartmut Goldschmidt, MD, Bernard Klein, Philipp Beckhove
Journal: Blood
Blood (2012) 120 (21): 2942.
https://doi.org/10.1182/blood.V120.21.2942.2942
Published: 2012
Journal Articles

Clinical and prognostic role of annexin A2 in multiple myeloma

Anja Seckinger, Tobias Meiβner, Jérôme Moreaux, Daniela Depeweg, Jens Hillengass, Katja Hose, Thierry Rème, Angela Rösen-Wolff, Anna Jauch, Reinhard Schnettler, Volker Ewerbeck, Hartmut Goldschmidt, Bernard Klein, Dirk Hose
Journal: Blood
Blood (2012) 120 (5): 1087–1094.
https://doi.org/10.1182/blood-2012-03-415588
Published: 2012
Includes: Supplemental data
Journal Articles

Prognostication by miRNome-Profiling in Multiple Myeloma

Anja Seckinger, Tobias Meißner, Vladimir Benes, Sabine Schmidt, Jonathan Blake, Jürgen Zimmermann, Hartmut Goldschmidt, MD, Bernard Klein, Dirk Hose
Journal: Blood
Blood (2011) 118 (21): 1822.
https://doi.org/10.1182/blood.V118.21.1822.1822
Published: 2011
Journal Articles

Metascoring and Gene Expression Profiling in Clinical Routine in Multiple Myeloma,

Tobias Meißner, Anja Seckinger, Thierry Rème, Thomas Hielscher, Thomas Möhler, Kai Neben, MD, Hartmut Goldschmidt, MD, Bernard Klein, Dirk Hose
Journal: Blood
Blood (2011) 118 (21): 3940.
https://doi.org/10.1182/blood.V118.21.3940.3940
Published: 2011
Journal Articles

Survivin in Multiple Myeloma: Prognostic and Therapeutic Implications

Verena Wagner, Dirk Hose, MD, Anja Seckinger, Ludmila Weitz, MSc, Tobias Meißner, Thierry Reme, Jean-Francois Rossi, MD, PhD, Hartmut Goldschmidt, MD, Alwin Krämer, MD, Bernard Klein, Marc S Raab, MD
Journal: Blood
Blood (2011) 118 (21): 137.
https://doi.org/10.1182/blood.V118.21.137.137
Published: 2011