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Journal Articles

Prevalence of Inherited Predisposition Syndromes in Young Patients with Acute Myeloid Leukemia and Aberrant Karyotype

Martin Kirschner, Benjamin Rolles, MD, Martina Crysandt, Christoph Röllig, Prof., MD, Friedrich Stolzel, MD, Martin Bornhäuser, MD, Carsten Müller-Tidow, MD, Kim Kricheldorf, Margherita Vieri, PhD, Matthias Begemann, Angela Maurer, Jens Panse, MD, Susanne Isfort, Marcin Wlodarski, MD PhD, Sushree Sangita Sahoo, PhD, Tim H Brümmendorf, MD, Edgar Jost, Fabian Beier, MD

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-142815

Published: 2020

Journal Articles

RPA1 Gain of Function Causes Human Short Telomere Syndrome with Revertant Somatic Mosaicism

Richa Sharma, MD, Sushree Sangita Sahoo, PhD, Masayoshi Honda, Charnise Goodings-Harris, PhD, Victor Pastor, PhD, Hauke Busch, PhD, Melanie Börries, PhD, Fabian Beier, MD, Miriam Erlacher, MD PhD, Melchior Lauten, Marc Wold, PhD, Maria Spies, PhD, Charlotte M. Niemeyer, MD, Marcin Wlodarski, MD PhD

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-143006

Published: 2020

Journal Articles

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Dimitrios Mougiakakos, MD, Simon Voelkl, PhD, Christian Bach, Andrej Stoll, Katrin Bitterer, Fabian Beier, MD, Jan Endell, Rainer Boxhammer, Jörg Thomas Bittenbring, MD, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 4064.

https://doi.org/10.1182/blood-2019-124886

Published: 2019

Journal Articles

Common Variable Immunodeficiency (CVID) in Adults As First Manifestation of (cryptic) Dyskeratosis Congenita

Benjamin Rolles, MD, Alla Bulashevska, PhD, Michele Proietti, MD, Sigune Goldacker, MD, Klaus Warnatz, MD, Nadezhda Camacho-Ordonez, MD, Margherita Vieri, MSc, Martin Kirschner, MD, Tim H Brümmendorf, MD, Bodo Grimbacher, MD, Fabian Beier, MD

Blood (2019) 134 (Supplement_1): 1217.

https://doi.org/10.1182/blood-2019-128915

Published: 2019

Journal Articles

Androgen Derivatives Improve Blood Counts and Elongate Telomere Length in Patients with Dyskeratosis Congenita

Martin Kirschner, MD, Monica Sofia Ventura Ferreira, PhD, Anne-Sophie Bouillon, MD, Marcin W. Wlodarski, MD PhD, Michaela Schwarz, MD, Stefan Balabanov, MD PhD, Stefan Wilop, MD, Steffen Koschmieder, MD, Jens P. Panse, MD, Tim H. Brümmendorf, MD, Fabian Beier, MD

Blood (2018) 132 (Supplement 1): 2585.

https://doi.org/10.1182/blood-2018-99-118197

Published: 2018

Journal Articles

Comparison of Fluorescence in Situ Hybridization and Flow Cytometry (Flow-FISH) with Monochrome Multiplex Quantitative Polymerase Chain Reaction (MM-qPCR) for Telomere Length Screening in Adult Patients with Suspected Cryptic Dyskeratosis Congenita (DKC)

Monica Sofia Ventura Ferreira, PhD, Natalia Estrada, Martin Kirschner, MD, Blanca Xicoy, Anne-Sophie Bouillon, MD, Stefan Wilop, MD, Steffen Koschmieder, MD, Jens P. Panse, MD, Tim H. Brümmendorf, MD, Fabian Beier, MD

Blood (2018) 132 (Supplement 1): 3861.

https://doi.org/10.1182/blood-2018-99-117330

Published: 2018

Journal Articles

Detection of Clonal Hematopoiesis Is a Rare Event in Patients with Dyskeratosis Congenita

Martin Kirschner, MD, Angela Maurer, Marcin W. Wlodarski, MD PhD, Monica Sofia Ventura Ferreira, Anne-Sophie Bouillon, MD, Wolfgang Blau, Michael Kreuter, MD, Martin Rosewich, Selim Corbacioglu, MD PhD, Joachim Beck, MD, C. Matthias Wilk, MD, Steffen Koschmieder, Fabian Beier, MD, Tim H. Brummendorf, MD

Blood (2017) 130 (Supplement 1): 2457.

https://doi.org/10.1182/blood.V130.Suppl_1.2457.2457

Published: 2017

Journal Articles

Analysis of the Hematopoietic System in Long-Term Survivors of Allogeneic Stem Cell Transplantation and Their Respective Donors

C. Matthias Wilk, MD, Steffen Boettcher, MD, Fabian Beier, MD, Tim H. Brümmendorf, MD, Markus G Manz, MD

Blood (2017) 130 (Supplement 1): 1996.

https://doi.org/10.1182/blood.V130.Suppl_1.1996.1996

Published: 2017

Journal Articles

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Heiko Bruns, PhD, Dimitrios Mougiakakos, Christian Bach, Martin Böttcher, Joerg Thomas Bittenbring, MD, Maike Büttner, Kolja Gelse, Michael Rehli, Julia Wimmer, Fabian Beier, MD, Deniz Gezer, Jan Krönke, MD, Heidi Balzer, Stephanie Moi, Bernd Spriewald, MD, Andreas Mackensen, MD, Leonhard Busch

Blood (2016) 128 (22): 2514.

https://doi.org/10.1182/blood.V128.22.2514.2514

Published: 2016

Journal Articles

Telomere Length Shortening in the CML Leukemic Stem Cell Compartment Correlates with the Respective Clone Size: Evidence for Early Vs. Late Chronic Phase

Anne-Sophie Bouillon, Monica S. Ferreira, PhD, Shady Adnan Awad, Johan Richter, MD, Henrik Hjorth-Hansen, MD PhD, Thoas Fioretos, Sebastian Hummel, Mirle Schemionek, PhD, Satu Mustjoki, MD PhD, Fabian Beier, MD, Tim H. Brümmendorf, MD

Blood (2016) 128 (22): 4243.

https://doi.org/10.1182/blood.V128.22.4243.4243

Published: 2016

Journal Articles

Comprehensive Analysis of Telomere Biology in Patients with Aplastic Anemia and Hypoplastic Myelodysplastic Syndrome: Further Evidence for a Common Mechanism

Anne-Sophie Bouillon, Monica S. Ferreira, PhD, Benjamin Werner, PhD, Sebastian Hummel, Jens P. Panse, MD, Petra Reinecke, MD, Jennifer Schemenau, Rainer Haas, MD, Arne Traulsen, PhD, Tim H. Bruemmendorf, MD, Ulrich Germing, MD, Fabian Beier, MD

Blood (2015) 126 (23): 2858.

https://doi.org/10.1182/blood.V126.23.2858.2858

Published: 2015

Journal Articles

Comprehensive Genomic Analysis Provides Further Evidence That Iron Overload Can Induce Genetic Instability in Myelodysplastic Syndromes

Gina Westhofen, Christina Ganster, Fabian Beier, MD, Tienush Rassaf, Haifa Kathrin Al-Ali, MD, Reingard Stuhlmann, Ulrike Bacher, Tim H. Brümmendorf, Ulrich Germing, MD, Norbert Gattermann, MD, Detlef Haase, MD

Blood (2015) 126 (23): 2842.

https://doi.org/10.1182/blood.V126.23.2842.2842

Published: 2015

Journal Articles

Cooperating Effect of Rps14 , Csnk1a1 and miRNA145/miRNA146a Haploinsufficiency in the Activation of the Innate Immune System in Del(5q) MDS

Schneider K. Rebekka, MD, Monica Schenone, PhD, Monica Ferreira Ventura, PhD, Fabian Beier, MD, Tim H. Bruemmendorf, MD, Ulrich Germing, MD, Uwe Platzbecker, MD, Guntram Büsche, MD, Marie E. McConkey, PhD, Christopher S Waters, R. Coleman Lindsley, MDPhD, Benjamin L. Ebert, MD

Blood (2015) 126 (23): 356.

https://doi.org/10.1182/blood.V126.23.356.356

Published: 2015

Journal Articles

The 3-OH Derivative of the Polychlorinated Biphenyl (PCB)-28 Inhibits Telomerase Expression and Accelerates Telomere Shortening in Vitro : A Rationale for the Significantly Shortened Telomere Length Found in Peripheral Blood Lymphocytes of Workers Exposed to High Doses of Lower Chlorinated PCBs

Patrick Ziegler, PhD, Thomas Schettgen, PhD, Stefan Wilop, MD, Natalia Soares Quintete, PhD, Susanne Ziegler, PhD, Fabian Beier, MD, Monica S.V. Ferreira, PhD, Peter Uciechowski, PhD, Lothar Rink, PhD, Thomas Kraus, MD, Tim H. Brümmendorf, MD

Blood (2014) 124 (21): 4139.

https://doi.org/10.1182/blood.V124.21.4139.4139

Published: 2014

Journal Articles

Evidence for Premature Aging of (Clonal but also) Non-Clonal Hematopoietic Stem Cells in Patients with Acute Myeloid Leukemia (AML)

Martina Crysandt, MD, Monica S.V. Ferreira, PhD, Patrick Ziegler, PhD, Sebastian Hummel, Julian Kaufmann, Stefan Wilop, MD, Edgar Jost, MD, Wolfgang Wagner, MD PhD, Tim H. Brummendorf, MD PhD, Fabian Beier, MD

Blood (2014) 124 (21): 1048.

https://doi.org/10.1182/blood.V124.21.1048.1048

Published: 2014

Journal Articles

Telomere Length Of Granulocytes Significantly Increases During The First Six Months Of Lenalidomide Treatment In Patients With Isolated 5q- Syndrome

Fabian Beier, MD, Ulrich Germing, MD, Guntram Büsche, MD, Patrick Ziegler, PhD, Stefan Wilop, MD, Lucia Vankann, Norbert Gattermann, MD, Uwe Platzbecker, MD, PhD, Aristoteles Giagounidis, MD, PhD, Katharina S. Götze, MD, Wolf-Karsten Hofmann, Detlef Haase, MD, PhD, Hans Kreipe, MD, Jens Panse, MD, Tim H. Brümmendorf, MD

Blood (2013) 122 (21): 2781.

https://doi.org/10.1182/blood.V122.21.2781.2781

Published: 2013

Journal Articles

Telomere Shortening At Diagnosis Of Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Is Significantly More Pronounced In Patients With Less-Than-Optimal Versus Optimal Molecular Response (ELN criteria) After 12 Months Of Treatment With Nilotinib

Katrin Wenn, Lena Tomala, Fabian Beier, MD, Stefan Wilop, MD, Lucia Vankann, Christian Hasenbank, Oliver Frank, Claudia Walasek, Andreas Hochhaus, MD, Frank Giles, MD MB, Steffen Koschmieder, Patrick Ziegler, PhD, Tim H. Brümmendorf, MD

Blood (2013) 122 (21): 1471.

https://doi.org/10.1182/blood.V122.21.1471.1471

Published: 2013

Journal Articles

Enterocytes Of Patients With Uncontrolled Acute Graft Versus Host Disease Of The Gut Undergo Massive Telomere Shortening Compared To Unaffected Controls

Sebastian Hummel, Daniel Heudobler, MD, Elisabeth Huber, MD, Monica S Ventura Ferreira, PhD, Dirk Fahrenkamp, Karin Schmid, MD, Felix Gremse, PhD, Gerhard Müller-Newen, PhD, Patrick Ziegler, PhD, Edgar Jost, MD, Tim H. Brümmendorf, MD, Ernst Holler, MD, PhD, Fabian Beier, MD

Blood (2013) 122 (21): 4467.

https://doi.org/10.1182/blood.V122.21.4467.4467

Published: 2013

Journal Articles

Age-Associated DNA Methylation Signature Reveals Premature Aging In Patients With Aplastic Anemia and Dyskeratosis Congenita Which Correlates With Telomere Shortening

Fabian Beier, MD, Carola I. Weidner, Qiong Lin, Patrick Ziegler, PhD, Martin Zenke, Tim H. Brümmendorf, MD, Wolfgang Wagner, MD, PhD

Blood (2013) 122 (21): 1223.

https://doi.org/10.1182/blood.V122.21.1223.1223

Published: 2013

NARROW

Prevalence of Inherited Predisposition Syndromes in Young Patients with Acute Myeloid Leukemia and Aberrant Karyotype

RPA1 Gain of Function Causes Human Short Telomere Syndrome with Revertant Somatic Mosaicism

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Common Variable Immunodeficiency (CVID) in Adults As First Manifestation of (cryptic) Dyskeratosis Congenita

Androgen Derivatives Improve Blood Counts and Elongate Telomere Length in Patients with Dyskeratosis Congenita

Comparison of Fluorescence in Situ Hybridization and Flow Cytometry (Flow-FISH) with Monochrome Multiplex Quantitative Polymerase Chain Reaction (MM-qPCR) for Telomere Length Screening in Adult Patients with Suspected Cryptic Dyskeratosis Congenita (DKC)

Detection of Clonal Hematopoiesis Is a Rare Event in Patients with Dyskeratosis Congenita

Analysis of the Hematopoietic System in Long-Term Survivors of Allogeneic Stem Cell Transplantation and Their Respective Donors

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Telomere Length Shortening in the CML Leukemic Stem Cell Compartment Correlates with the Respective Clone Size: Evidence for Early Vs. Late Chronic Phase

Comprehensive Analysis of Telomere Biology in Patients with Aplastic Anemia and Hypoplastic Myelodysplastic Syndrome: Further Evidence for a Common Mechanism

Comprehensive Genomic Analysis Provides Further Evidence That Iron Overload Can Induce Genetic Instability in Myelodysplastic Syndromes

Cooperating Effect of Rps14 , Csnk1a1 and miRNA145/miRNA146a Haploinsufficiency in the Activation of the Innate Immune System in Del(5q) MDS

The 3-OH Derivative of the Polychlorinated Biphenyl (PCB)-28 Inhibits Telomerase Expression and Accelerates Telomere Shortening in Vitro : A Rationale for the Significantly Shortened Telomere Length Found in Peripheral Blood Lymphocytes of Workers Exposed to High Doses of Lower Chlorinated PCBs

Evidence for Premature Aging of (Clonal but also) Non-Clonal Hematopoietic Stem Cells in Patients with Acute Myeloid Leukemia (AML)

Genetic Characterization Of Aplastic Anemia Patients By Targeted Sequencing

Telomere Length Of Granulocytes Significantly Increases During The First Six Months Of Lenalidomide Treatment In Patients With Isolated 5q- Syndrome

Telomere Shortening At Diagnosis Of Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Is Significantly More Pronounced In Patients With Less-Than-Optimal Versus Optimal Molecular Response (ELN criteria) After 12 Months Of Treatment With Nilotinib

Enterocytes Of Patients With Uncontrolled Acute Graft Versus Host Disease Of The Gut Undergo Massive Telomere Shortening Compared To Unaffected Controls

Age-Associated DNA Methylation Signature Reveals Premature Aging In Patients With Aplastic Anemia and Dyskeratosis Congenita Which Correlates With Telomere Shortening

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American Society of Hematology

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ASH Publications

American Society of Hematology

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