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Journal Articles

First-hit SETBP1 mutations cause a myeloproliferative disorder with bone marrow fibrosis

Ilaria Crespiatico, Mattia Zaghi, Cristina Mastini, Deborah D’Aliberti, Mario Mauri, Carl Mirko Mercado, Diletta Fontana, Silvia Spinelli, Valentina Crippa, Elena Inzoli, Beatrice Manghisi, Ivan Civettini, Daniele Ramazzotti, Valentina Sangiorgio, Michele Gengotti, Virginia Brambilla, Andrea Aroldi, Federica Banfi, Cristiana Barone, Roberto Orsenigo, Ludovica Riera, Mara Riminucci, Alessandro Corsi, Massimo Breccia, Alessandro Morotti, Daniela Cilloni, Aldo Roccaro, Antonio Sacco, Fabio Stagno, Marta Serafini, Federica Mottadelli, Giovanni Cazzaniga, Fabio Pagni, Roberto Chiarle, Emanuele Azzoni, Alessandro Sessa, Carlo Gambacorti-Passerini, Elena Maria Elli, Luca Mologni, Rocco Piazza
Journal: Blood
Blood (2024) 143 (14): 1399–1413.
https://doi.org/10.1182/blood.2023021349
Published: 2024
Includes: Supplemental data
Journal Articles

First-Hit SETBP1 Mutations Cause a Myeloproliferative Disorder with Bone Marrow Fibrosis

Ilaria Crespiatico, Mattia Zaghi, Cristina Mastini, Deborah D'Aliberti, Mario Mauri, Carl Mirko Mercado, Diletta Fontana, Silvia Spinelli, Valentina Crippa, Elena Inzoli, Beatrice Manghisi, Ivan Civettini, Daniele Ramazzotti, Valentina Fabiola Ilenia Lavoro, Michele Gengotti, Virginia Brambilla, Andrea Aroldi, Federica Banfi, Cristiana Barone, Roberto Orsenigo, Ludovica Riera, Mara Riminucci, Alessandro Corsi, Massimo Breccia, Alessandro Morotti, Daniela Cilloni, Aldo Roccaro, Antonio Sacco, Fabio Stagno, Marta Serafini, Federica Mottadelli, Giovanni Cazzaniga, Fabio Pagni, Roberto Chiarle, Emanuele Azzoni, Alessandro Sessa, Carlo Gambacorti-Passerini, Elena Maria Elli, Luca Mologni, Rocco Piazza
Journal: Blood
Blood (2023) 142 (Supplement 1): 4135.
https://doi.org/10.1182/blood-2023-189094
Published: 2023
Journal Articles

On the Children Side. Overview of 194 Outcomes from Gimema Registry of Conception/Pregnancy in Chronic Myeloid Leukemia (CML)

Elisabetta Abruzzese, Elena Chiara, Fausto Castagnetti, Mario Annunziata, Carlo Gambacorti-Passerini, Luigiana Luciano, Antonella Russo Rossi, Alessandra Iurlo, Isabella Capodanno, Valentina Giai, Mariella D'Adda, Fabio Stagno, Antonella Gozzini, Mario Tiribelli, Federica Sorà, Sara Galimberti, Monica Bocchia, Germana Beltrami, Carmen Fava, Maria Cristina Miggiano, Massimo Breccia, Marco Cerrano, Anna Rita Scortechini, Olga Mulas, Clementina Caracciolo, Stefana Impera, Claudio Fozza, Alessandra Malato, Lucia Mastrullo, Marzia Salvucci, Monia Lunghi, Filippo Gherlinzoni, Paolo De Fabritiis, Paola Fazi, Sonia Maria Orlando, Alfonso Piciocchi, Fabrizio Pane
Journal: Blood
Blood (2023) 142 (Supplement 1): 3178.
https://doi.org/10.1182/blood-2023-188305
Published: 2023
Journal Articles

Full Treatment-Free Remission Outcome in Patients with Chronic Myeloid Leukemia in Chronic Phase Following One Year of Nilotinib De-Escalation: 96-Week Update of Dante Study

Alessandra Iurlo, Massimo Breccia, Fabio Stagno, Elisabetta Abruzzese, Fabrizio Pane, Immacolata Attolico, Paolo Sportoletti, Marco Cerrano, Sara Galimberti, Barbara Scappini, Maurizio Miglino, Sergio Siragusa, Isabella Capodanno, Diletta Valsecchi, Aurelio Pio Nardozza, Alessandra Misto, Paola Coco, Giuseppe Saglio, Gianantonio Rosti
Journal: Blood
Blood (2023) 142 (Supplement 1): 4534.
https://doi.org/10.1182/blood-2023-180131
Published: 2023
Journal Articles

3-YEARS and Beyond Study Completion Results of the Otpkima Randomized Clinical Trial in Elderly CML Patients

Michele Malagola, Alessandra Iurlo, Cristina Bucelli, Elisabetta Abruzzese, Massimiliano Bonifacio, Fabio Stagno, Gianni Binotto, Mariella D'Adda, Monia Lunghi, Monica Crugnola, Maria Luisa Ferrari, Francesca Lunghi, Fausto Castagnetti, Gianantonio Rosti, Roberto Massimo Lemoli, Rosaria Sancetta, Maria Rosaria Coppi, Maria Teresa Corsetti, Matteo Dalmazzo, Atelda Romano, Mario Tiribelli, Antonella Russo Rossi, Sabina Russo, Anna Sicuranza, Aldo Roccaro, Giulia Butturini, Mirko Farina, Simona Bernardi, Simone Pellizzeri, Nicola Polverelli, Domenico Russo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2023-177619
Published: 2023
Journal Articles

Loss of Function of SETD2 Tumor Suppressor in Chronic Myeloid Leukemia (CML) Progenitors Fosters Genomic Instability and Enhances Clonogenic Potential

Sara De Santis, Manuela Mancini, Cecilia Monaldi, Gabriele Gugliotta, Samantha Bruno, Fausto Castagnetti, Miriam Iezza, Marco Cerrano, Alessandra Iurlo, Sara Galimberti, Serena Balducci, Fabio Stagno, Michele Cavo, Simona Soverini
Journal: Blood
Blood (2023) 142 (Supplement 1): 1785.
https://doi.org/10.1182/blood-2023-185677
Published: 2023
Journal Articles

Efficacy of Frontline Treatment with Initial Low-Dose Tyrosine-Kinase Inhibitors in Elderly Patients with Chronic Myeloid Leukemia: A “Campus CML” Study

Cristina Bucelli, Isabella Capodanno, Maria Cristina Miggiano, Francesco Cavazzini, Sabrina Leonetti Crescenzi, Sabina Russo, Ida Carmosino, Mario Annunziata, Federica SORA, Massimiliano Bonifacio, Luigiana Luciano, Giovanni Caocci, Giuseppina Loglisci, Chiara Elena, Francesca Lunghi, Rikard Mullai, Imma Attolico, Gianni Binotto, Elena Crisa', Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Anna Paola Leporace, Alessandro Maggi, Monica Crugnola, Fabio Stagno, Rosaria Sancetta, Pamela Murgano, Davide Rapezzi, Debora Luzi, Jolanda Donatella Vincelli, Sara Galimberti, Monica Bocchia, Carmen Fava, Alessandra Malato, Elisabetta Abruzzese, Giuseppe Saglio, Giorgina Specchia, Massimo Breccia, Alessandra Iurlo, Mario Tiribelli, Roberto Latagliata
Journal: Blood
Blood (2023) 142 (Supplement 1): 3176.
https://doi.org/10.1182/blood-2023-186406
Published: 2023
Journal Articles

The Use of 2 nd Generation TKIs As First Line Therapy Does Not Prevent CML Related Deaths: Results of an Italian CML Campus Prospective Study in 1277 Patients Treated First Line with Imatinib or 2 nd Generation TKIs

Valentina Giai, Fabio Stagno, Tiziana Rosso, Fausto Castagnetti, Isabella Capodanno, Massimiliano Bonifacio, Mario Tiribelli, Sara Galimberti, Monica Bocchia, Antonella Gozzini, Giovanni Caocci, Andrea Patriarca, Giuseppe Lanzarone, Anna Guella, Federica Sorà, Luigiana Luciano, Anna Rita Scortechini, Nicola Di Renzo, Pellegrino Musto, Domenico Pastore, Alessandro Maggi, Carmen Fava, Vincenzo Pavone, Claudio Fozza, Giuseppina Spinosa, Angelo Michele Carella, Giuseppe Tarantini, Bruno Martino, Michele Pizzuti, Clara Mannarella, Fabio Saccona, Gianantonio Rosti, Patrizia Pregno, Massimo Breccia, Fabrizio Pane, Giovannino Ciccone, Giorgina Specchia, Giuseppe Saglio
Journal: Blood
Blood (2023) 142 (Supplement 1): 3168.
https://doi.org/10.1182/blood-2023-182981
Published: 2023
Journal Articles

Outcome of Patients with Chronic Myeloid Leukemia in Chronic Phase Showing Clinical Resistance to Frontline Treatment with Second Generation Tyrosine Kinase Inhibitors. an Italian Prospective Study from the CML Campus

Fabio Stagno, Valentina Giai, Patrizia Pregno, Gabriele Gugliotta, Tiziana Rosso, Fausto Castagnetti, Isabella Capodanno, Massimiliano Bonifacio, Mario Tiribelli, Sara Galimberti, Monica Bocchia, Antonella Gozzini, Giovanni Caocci, Andrea Patriarca, Giuseppe Lanzarone, Anna Guella, Simona Sica, Luigiana Luciano, Anna Rita Scortechini, Maria Pia Loglisci, Antonella Russo Rossi, Maria Rosaria Coppi, Alessandro Maggi, Maria Teresa Santeramo, Carmen Fava, Giuseppina Greco, Claudio Fozza, Giuseppina Spinosa, Grazia Sanpaolo, Bruno Martino, Michele Pizzuti, Giuseppe Pietrantuono, Fabio Saccona, Gianantonio Rosti, Massimo Breccia, Fabrizio Pane, Giovannino Ciccone, Giorgina Specchia, Giuseppe Saglio
Journal: Blood
Blood (2023) 142 (Supplement 1): 6363.
https://doi.org/10.1182/blood-2023-188523
Published: 2023
Journal Articles

Baseline Features, Treatment Choice and Early Frontline TKI Permanent Discontinuation in Younger Patients with Chronic Myeloid Leukemia: A “Campus CML” Study

Francesco Cavazzini, Isabella Capodanno, Maria Cristina Miggiano, Cristina Bucelli, Sabrina Leonetti Crescenzi, Sabina Russo, Ida Carmosino, Atelda Romano, Federica Sorà, Massimiliano Bonifacio, Luigiana Luciano, Giovanni Caocci, Maria Pia Loglisci, Chiara Elena, Francesca Lunghi, Rikard Mullai, Immacolata Attolico, Gianni Binotto, Elena Crisà, Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Anna Paola Leporace, Alessandro Maggi, Monica Crugnola, Fabio Stagno, Marco Santoro, Pamela Murgano, Davide Rapezzi, Debora Luzi, Jolanda Donatella Vincelli, Sara Galimberti, Monica Bocchia, Carmen Fava, Alessandra Malato, Elisabetta Abruzzese, Giuseppe Saglio, Giorgina Specchia, Massimo Breccia, Alessandra Iurlo, Mario Tiribelli, Roberto Latagliata
Journal: Blood
Blood (2023) 142 (Supplement 1): 1811.
https://doi.org/10.1182/blood-2023-188934
Published: 2023
Journal Articles

Risk of Progression in Chronic Phase-Chronic Myeloid Leukemia (CML) Patients Eligible for Tyrosine Kinase Inhibitor Discontinuation: The Tfr-PRO Study

Giovanni Zambrotta, Sarit Assouline, Franck E. Nicolini, Elisabetta Abruzzese, Maria Cristina Miggiano, Chiara Elena, Alberto Alvarez-Larran, Ana Triguero, Alessandra Iurlo, Cristina Bucelli, Francesca Lunghi, Isabella Capodanno, Margherita Maffioli, Sara Galimberti, Giovanni Caocci, Fabio Stagno, Susanne Saussele, Carmen Fava, Philipp le Coutre, Massimiliano Bonifacio, Veronica Guglielmana, Federica Colombo, Laura Antolini, Carlo Gambacorti-Passerini
Journal: Blood
Blood (2022) 140 (Supplement 1): 1504–1506.
https://doi.org/10.1182/blood-2022-162207
Published: 2022
Journal Articles

Treatment-Free Remission Outcome in Patients with Chronic Myeloid Leukemia in Chronic Phase Following One Year of Nilotinib De-Escalation: 96-Week Update of Dante Study

Fabio Stagno, Elisabetta Abruzzese, Alessandra Iurlo, Fabrizio Pane, Imma Attolico, Paolo Sportoletti, Patrizia Pregno, Sara Galimberti, Barbara Scappini, Maurizio Miglino, Sergio Siragusa, Isabella Capodanno, Diletta Valsecchi, Aurelio Pio Nardozza, Paola Coco, Gianantonio Rosti, Giuseppe Saglio, Massimo Breccia
Journal: Blood
Blood (2022) 140 (Supplement 1): 9614–9616.
https://doi.org/10.1182/blood-2022-157700
Published: 2022
Journal Articles

A Phase II, Single-Arm Study of De-Escalation and Treatment-Free Remission in Patients with Chronic Myeloid Leukemia Treated with Nilotinib in First-Line Therapy Followed By a Second Attempt after Nilotinib and Asciminib Combination: Dante Study

Gianantonio Rosti, Giuseppe Saglio, Fabio Stagno, Diletta Valsecchi, Aurelio Pio Nardozza, Paola Coco, Massimo Breccia, Alessandra Iurlo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9643–9644.
https://doi.org/10.1182/blood-2022-157002
Published: 2022
Journal Articles

Choice of Tyrosine Kinase Inhibitor and Early Events during the First Year of Therapy in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia (CML) Patients with Concomitant Diabetes: A "Campus CML" Study

Isabella Capodanno, Mario Tiribelli, Maria Cristina Miggiano, Cristina Bucelli, Francesco Cavazzini, Sabrina Leonetti Crescenzi, Sabina Russo, Emilia Scalzulli, Andrea Bernardelli, Luigiana Luciano, Olga Mulas, Giuseppina Loglisci, Chiara Elena, Umberto Pizzano, Immacolata Attolico, Gianni Binotto, Elena Crisà, Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Annapaola Leporace, Maria Basile, Monica Crugnola, Fabio Stagno, Pamela Murgano, Davide Rapezzi, Debora Luzi, Alessandra Iurlo, Monica Bocchia, Carmen Fava, Alessandra Malato, Sara Galimberti, Iolanda Donatella Vincelli, Malgorzata Monika Trawinska, Michele Pizzuti, Giovanni Caocci, Massimiliano Bonifacio, Giuseppe Saglio, Giorgina Specchia, Massimo Breccia, Roberto Latagliata
Journal: Blood
Blood (2022) 140 (Supplement 1): 3920–3922.
https://doi.org/10.1182/blood-2022-164790
Published: 2022
Journal Articles

Nursing Management of Frail Patients with Hematologic Malignancies during COVID-19 Pandemia in the Viterbo Domiciliary Care Unit: Data Analysis from March 2020 to March 2021

Silvia Ciambella, Vincenza Innocenti, Elisa Emanueli Cippitelli, Silvia Bertelli, Roberta Talucci, Valentina Panichi, Giuseppe Topini, Alessia Fiorini, Ambra Di Veroli, Caterina Mercanti, Fiammetta Natalino, Gioia De Angelis, Michela Tarnani, Marco Morucci, Cristina Mastino, Fabio Stagno, Giulio Trapè, Assunta Silvestri, Marco Montanaro, Roberto Latagliata
Journal: Blood
Blood (2021) 138 (Supplement 1): 3022.
https://doi.org/10.1182/blood-2021-150276
Published: 2021
Journal Articles

Analysis of Early Events during the First Year of Tyrosine Kinase Inhibitor Therapy in Patients with Chronic Phase - Chronic Myeloid Leukemia: A "Campus CML" Study

Mario Tiribelli, Isabella Capodanno, Maria Cristina Miggiano, Cristina Bucelli, Francesco Cavazzini, Sabrina Leonetti Crescenzi, Sabina Russo, Emilia Scalzulli, Andrea Bernardelli, Luigiana Luciano, Olga Mulas, Giuseppina Loglisci, Chiara Elena, Umberto Pizzano, Immacolata Attolico, Gianni Binotto, Elena Crisà, Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Annapaola Leporace, Maria Basile, Monica Crugnola, Fabio Stagno, Pamela Murgano, Davide Rapezzi, Alessandra Malato, Michele Pizzuti, Debora Luzi, Malgorzata Monika Trawinska, Alessandra Iurlo, Monica Bocchia, Carmen Fava, Giovanni Caocci, Massimiliano Bonifacio, Giuseppe Nicola Saglio, Giorgina Specchia, Massimo Breccia, Roberto Latagliata
Journal: Blood
Blood (2021) 138 (Supplement 1): 1487.
https://doi.org/10.1182/blood-2021-149780
Published: 2021
Journal Articles

Choice of Frontline Tyrosine-Kinase Inhibitor in Very Elderly Patients with Chronic Myeloid Leukemia: A "Campus CML" Study

Roberto Latagliata, Isabella Capodanno, Maria Cristina Miggiano, Cristina Bucelli, Francesco Cavazzini, Sabrina Leonetti Crescenzi, Sabina Russo, Gioia Colafigli, Mario Annunziata, Federica Sora, Massimiliano Bonifacio, Luigiana Luciano, Giovanni Caocci, Giuseppina Loglisci, Chiara Elena, Rikard Mullai, Imma Attolico, Gianni Binotto, Elena Crisà, Alessandra Iurlo, Paolo Sportoletti, Ambra Di Veroli, Anna Rita Scortechini, Annapaola Leporace, Alessandro Maggi, Monica Crugnola, Fabio Stagno, Rosaria Sancetta, Pamela Murgano, Davide Rapezzi, Debora Luzi, Monica Bocchia, Carmen Fava, Alessandra Malato, Jolanda Donatella Vincelli, Elisabetta Abruzzese, Giuseppe Nicola Saglio, Giorgina Specchia, Massimo Breccia, Mario Tiribelli
Journal: Blood
Blood (2021) 138 (Supplement 1): 3617.
https://doi.org/10.1182/blood-2021-151538
Published: 2021
Journal Articles

First Interim Analysis of the Italian Dante Study: De-Escalation before Treatment-Free Remission in Patients with Chronic Myeloid Leukemia Treated with First-Line Nilotinib

Massimo Breccia, Elisabetta Abruzzese, Fabio Stagno, Alessandra Iurlo, Fabrozio Pene, Immacolata Attolica, Paolo Sportoletti, Patrizia Pregno, Sara Galimberti, Barbara Scappini, Roberto M. Lemoli, Sergio Siragusa, Isabella Capodanno, Francesca Chiodi, Giuseppe Nicola Saglio, Gianantonio Rosti
Journal: Blood
Blood (2021) 138 (Supplement 1): 1474.
https://doi.org/10.1182/blood-2021-145411
Published: 2021
Journal Articles

Pro-Inflammatory and Pro-Oxidative Changes during Nilotinib Treatment in CML Patients: Results of a Prospective Multicenter Front-Line TKIs Study (KIARO Study)

Anna Sicuranza, Ilaria Ferrigno, Elisabetta Abruzzese, Alessandra Iurlo, Sara Galimberti, Antonella Gozzini, Luigiana Luciano, Fabio Stagno, Antonella Russo Rossi, Nicola Sgherza, Daniele Cattaneo, Corrado Zuanelli Brambilla, Cristina Marzano, Carmen Fava, Olga Mulas, Emanuele Cencini, Alessandro Gozzetti, Luca Puccetti, Monica Bocchia
Journal: Blood
Blood (2021) 138 (Supplement 1): 1479.
https://doi.org/10.1182/blood-2021-152530
Published: 2021
Journal Articles

Increased tumor burden in patients with chronic myeloid leukemia after 36 months of imatinib discontinuation

Clinical Trials & Observations
Elisa Diral, Silvia Mori, Laura Antolini, Elisabetta Abruzzese, Philipp Le Coutre, Bruno Martino, Ester Pungolino, Chiara Elena, Micaela Bergamaschi, Sarit Assouline, Eros Di Bona, Antonella Gozzini, Marcio Andrade-Campos, Fabio Stagno, Alessandra Iurlo, Alessandra Pirola, Diletta Fontana, Jessica Petiti, Maria Luisa Bonanomi, Patrizia Crivori, Rocco Piazza, Carmen Fava, Carlo Gambacorti-Passerini
Journal: Blood
Blood (2020) 136 (19): 2237–2240.
https://doi.org/10.1182/blood.2019004371
Published: 2020
Includes: Supplemental data