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Journal Articles

LP-118, a Novel BCL2 Inhibitor, Shows Potent in Vitro Anti-Myeloma Activity

Rodrigo Fonseca, Yuan Xiao Zhu, P. Leif Bergsagel, Marta Chesi, Akhilesh Pandey, Kiran Mangalaparthi, Yi Chen, Felai Tan, Stephen P. Anthony, Yu Chen, Yue Shen, Bing Dai, Esteban Braggio, Rafael Fonseca
Journal: Blood
Blood (2022) 140 (Supplement 1): 7129–7130.
https://doi.org/10.1182/blood-2022-167372
Published: 2022
Journal Articles

LP-118, a Selective Bcl-2 Inhibitor with Tuned Bcl-Xl Activity, Causes Myeloid Differentiation and Cell Death in Acute Myeloid Leukemia (AML)

Kristin L Koenig, Colin Brame, Steven Sher, Larry Beaver, Casey B. Cempre, Katie Williams, Matthew Purcell, Bonnie Harrington, Yi Chen, Felai Tan, Stephen P. Anthony, Yu Chen, Yue Shen, John C. Byrd, Rosa Lapalombella
Journal: Blood
Blood (2022) 140 (Supplement 1): 9068–9069.
https://doi.org/10.1182/blood-2022-170578
Published: 2022
Journal Articles

Targeting Apoptosis with Novel BH3 Mimetics in T-Lineage Acute Lymphoblastic Leukemia

Caner Saygin, Bartholomew Eisfelder, Giorgia Giordano, Anika Thomas-Toth, Yi Chen, Felai Tan, Stephen P. Anthony, Yu Chen, Yue Shen, James LaBelle, Wendy Stock
Journal: Blood
Blood (2022) 140 (Supplement 1): 10689–10690.
https://doi.org/10.1182/blood-2022-163673
Published: 2022
Journal Articles

Characterization of LP-118, a Novel Small Molecule Inhibitor of Bcl-2 and Bcl-Xl in Chronic Lymphocytic Leukemia Resistant to Venetoclax

Janani Ravikrishnan, Elizabeth M. Muhowski, Tzung-Huei Lai, Shrilekha Misra, Daisy Diaz Rohena, Felai Tan, Yi Chen, Stephen P. Anthony, Yu Chen, Yue Shen, John C. Byrd, Deepa Sampath, Jennifer A. Woyach
Journal: Blood
Blood (2021) 138 (Supplement 1): 679.
https://doi.org/10.1182/blood-2021-151852
Published: 2021