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Geneviève Plat
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Journal Articles

Population Pharmacokinetics of Inotuzumab Ozogamicin (InO) As Single Agent in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia - Results from the ITCC-059 Phase IA and Phase II Trial

Edoardo Pennesi, Erica Brivio, Kathleen B. Pelletier, Ying Chen, Alwin D.R. Huitema, Yilin Jiang, Anneke C.J. Ammerlaan, Barbara Sleight, Franco Locatelli, Inge M. Van Der Sluis, Claudia Rossig, Christiane Chen-Santel, Bella Bielorai, Arnaud Petit, Jan Stary, Lucie Sramkova, Cristina Díaz de Heredia Rubio, Susana Rives, Aengus O'Marcaigh, Carmelo Rizzari, Gernot Engstler, Karsten Nysom, Alba Rubio-San-Simón, Francisco J. Bautista Sirvent, Bénédicte Bruno, Yives Bertrand, Benoit Brethon, Fanny Rialland, Genevieve Plat, Uta Dirksen, May Garrett, Christian M. Zwaan
Journal: Blood
Blood (2022) 140 (Supplement 1): 8845–8847.
https://doi.org/10.1182/blood-2022-165954
Published: 2022
Journal Articles

Cardiac and Vascular Risks Are the Essential Parameters for Long-Term Surveillance of Lower Risk Childhood Acute Leukemia Survivors

Paul Saultier, Nour El Riachy, Yves Bertrand, Marie-Dominique Tabone, Guy Leverger, Jean-Hugues Dalle, Andre Baruchel, Cecile Pochon, Catherine Paillard, Stephane Ducassou, Marilyne Poiree, Dominique Plantaz, Justyna Kanold, Virginie Gandemer, Nicolas Sirvent, Genevieve Plat, Isabelle Pellier, Yves Reguerre, Sandrine Thouvenin, Audrey Françoise Petit, Pascal Auquier, Julie Berbis, Gerard Michel
Journal: Blood
Blood (2022) 140 (Supplement 1): 2187–2189.
https://doi.org/10.1182/blood-2022-157345
Published: 2022
Journal Articles

A Phase II Study of Single-Agent Inotuzumab Ozogamicin in Pediatric CD22-Positive Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of the ITCC-059 Study

Erica Brivio, MD, Franco Locatelli, MD, Adriana Thano, Arnaud Petit, MD PhD, Britta Julia Vormoor, MD, Susana Rives, Bella Bielorai, MD, Claudia Rossig, Carmelo Rizzari, Vincent H.J. Van Der Velden, PhD, Anneke C.J. Ammerlaan, Monique L. Den Boer, PhD, Barbara Sleight, MD, Gernot Engstler, Jan Stary, MD PhD, Francisco José Bautista Sirvent, MD PhD, Christiane Chen-Santel, Bénédicte Bruno, MD, Yves Bertrand, MD, Fanny Rialland, MD, Geneviève Plat, Dirk Reinhardt, MD, Luciana Vinti, MD, Arend von Stackelberg, MD, Christian Michel Zwaan
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-134774
Published: 2020
Journal Articles

Socioeconomic Outcomes Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Melissa Barbati, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Teresa De Rojas, MD, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2191.
https://doi.org/10.1182/blood.V130.Suppl_1.2191.2191
Published: 2017
Journal Articles

Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Teresa De Rojas, MD, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2563.
https://doi.org/10.1182/blood.V130.Suppl_1.2563.2563
Published: 2017
Journal Articles

Prophylactic CNS Therapy (with or without Radiation Therapy) in Medium-High Risk Acute Lymphoblastic Leukemia (ALL) Children: Long-Term Outcome Evaluation of the Randomized BFM-Oriented Trial 58832 (period 1983-1989) of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Yves Bertrand, Anne Uyttebroeck, Els Vandecruys, Geneviève Plat, Patrick Lutz, Claire Pluchart, Nicolas Sirvent, Maryline Poirée, Pauline Simon, Alina Ferster, Claire Hoyoux, Francoise Mazingue, Robert Paulus, Dominique Plantaz, Caroline Thomas, Caroline Gilotay, Jutte Van Der Werff Ten Bosch, Pierre Simon Rohrlich, Yves Benoit
Journal: Blood
Blood (2016) 128 (22): 2775.
https://doi.org/10.1182/blood.V128.22.2775.2775
Published: 2016
Journal Articles

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

Farzaneh Ghazavi, Barbara De Moerloose, MD, Wouter Van Loocke, Annelynn Wallaert, Alina Ferster, Marleen Bakkus, PhD, Genevieve Plat, MD, Eric Delabesse, PharmD, PhD, Anne Uyttebroeck, Filip Van Nieuwerburgh, PharmD, Prof, Dieter Deforce, PharmD, Prof, Nadine van Roy, MD Prof, Frank Speleman, Prof, Yves Benoit, Tim Lammens, Pieter van Vlierberghe, Prof
Journal: Blood
Blood (2016) 128 (22): 3920.
https://doi.org/10.1182/blood.V128.22.3920.3920
Published: 2016
Journal Articles

Impact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study

Laura Clement, Stefan Suciu, PhD, Isabelle Luquet, MD, Alina Ferster, MD PhD, Karima Yakouben, MD, Anne Uytterbroeck, Catherine Paillard, MD PhD, Nicolas Sirvent, Vitor Costa, Barbara De Moerloose, MD, Francoise Mazingue, Emmanuel Plouvier, MD, Martine Munzer, Maryline Poirée, Odile Minckes, MD, Frédéric Millot, MD, Dominique Plantaz, Caroline Piette, Frank Speleman, Prof, Hélène Cavé, Jutte VanderWerff-tenBossch, Pierre Simon Rohrlich, MDPhD, Yves Bertrand, Yves Benoit, Geneviève Plat
Journal: Blood
Blood (2016) 128 (22): 1743.
https://doi.org/10.1182/blood.V128.22.1743.1743
Published: 2016
Journal Articles

Evaluation of the Impact of the Presence of Neutralizing L-Asparaginase Antibodies on the Efficacy and Safety of Graspa in Phase 3 Randomized Trial Versus Native L-Asparaginase in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Yves Bertrand, MDPhD, Andre Baruchel, MD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3734.
https://doi.org/10.1182/blood.V126.23.3734.3734
Published: 2015
Journal Articles

Updated Clinical Activity of Graspa Versus Native l-Asparaginase in Combination with Cooprall Regimen in Phase 3 Randomized Trial in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Andre Baruchel, MD, Yves Bertrand, MD PhD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, MDPhD, Genevieve PLAT, Jose Fernandes, MD, Poiree Maryline, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, MD, Cecile Bonin, Pharm D, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3723.
https://doi.org/10.1182/blood.V126.23.3723.3723
Published: 2015
Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Emmanuelle Clappier, Yves Bertrand, MDPhD, Genevieve Plat, MD, Christophe Chantrain, Vitor Costa, Nicole Dastugue, Alina Ferster, Caroline Gilotay, Sandrine Girard, Nathalie Grardel, Patrick Lutz, Francoise Mazingue, MD, Odile Minckes, Martine Munzer, Emmanuel Plouvier, MD, Nicolas Sirvent, Anne Uyttebroeck, Nadine van Roy, MD, Karima Yakouben, MD, Yves Benoit, Hélène Cavé
Journal: Blood
Blood (2015) 126 (23): 793.
https://doi.org/10.1182/blood.V126.23.793.793
Published: 2015
Journal Articles

Pharmacokinetic and Pharmacodynamic Characterization of Graspa Versus Native L-Asparaginase in Combination with Cooprall Chemotherapy in a Phase 3 Randomized Trial for the Treatment of Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Xavier Thomas, MD PhD, Yves Bertrand, MDPhD, Andre Baruchel, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 2492.
https://doi.org/10.1182/blood.V126.23.2492.2492
Published: 2015
Journal Articles

Advanced Stage Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) in Children and Adolescents : Retrospective Study from Sfce and Ukccssg

Roques Gaelle, physician fellow, Ananth Shankar, MD, Thierry Leblanc, MD, Claudine Schmitt, MD, Janis Hayward, MD, Helene Pacquement, Anne Lambilliotte, Nathalie Aladjidi, MD, Stephanie gorde-Grosjean, Hewitt Martin, MD, Stephanie Haouy, Samuel Abbou, Dominique Plantaz, MD PhD, Genevieve Plat, Georgina Hall, BSc, PhD MBBS, FRCP, FRCPath, Judith Landman-Parker, Pr
Journal: Blood
Blood (2014) 124 (21): 4413.
https://doi.org/10.1182/blood.V124.21.4413.4413
Published: 2014
Journal Articles

Prognostic Relevance of CD200 /Btla Deletions in Pediatric Precursor-B Cell Acute Lymphoblastic Leukemia Treated According to the EORTC-CLG 58951 Protocol

Farzaneh Ghazavi, Tim Lammens, Emmanuelle Clappier, Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Yves Bertrand, Odile Minckes, Vitor Costa, Alina Ferster, Françoise Mazingue, Geneviève Plat, Emmanuel Plouvier, Marilyne Poirée, Anne Uyttebroeck, Jutte Van der Werff Ten Bosch, Hetty Helsmoortel, Magali Meul, Nadine Van Roy, Jan Philippé, Frank Speleman, Hélène Cavé, Pieter Van Vlierberghe, Barbara De Moerloose
Journal: Blood
Blood (2014) 124 (21): 2394.
https://doi.org/10.1182/blood.V124.21.2394.2394
Published: 2014
Journal Articles

Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results

Clinical Trials & Observations
Nicole Dastugue, Stefan Suciu, Geneviève Plat, Frank Speleman, Hélène Cavé, Sandrine Girard, Marleen Bakkus, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, Anne Uyttebroeck, Carine Gervais, Patrick Lutz, Manuel R. Teixeira, Pierre Heimann, Alice Ferster, Pierre Rohrlich, Marie Agnès Collonge, Martine Munzer, Isabelle Luquet, Patrick Boutard, Nicolas Sirvent, Matthias Karrasch, Yves Bertrand, Yves Benoit
Journal: Blood
Blood (2013) 121 (13): 2415–2423.
https://doi.org/10.1182/blood-2012-06-437681
Published: 2013
Includes: Supplemental data
Journal Articles

High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia

Marlène Pasquet, Christine Bellanné-Chantelot, Suzanne Tavitian, Naïs Prade, Blandine Beaupain, Olivier LaRochelle, Arnaud Petit, Pierre Rohrlich, Christophe Ferrand, Eric Van Den Neste, Hélène A. Poirel, Thierry Lamy, Marie Ouachée-Chardin, Véronique Mansat-De Mas, Jill Corre, Christian Récher, Geneviève Plat, Françoise Bachelerie, Jean Donadieu, Eric Delabesse
Journal: Blood
Blood (2013) 121 (5): 822–829.
https://doi.org/10.1182/blood-2012-08-447367
Published: 2013
Includes: Supplemental data
Journal Articles

Safety of Clofarabine with Multiagent Chemotherapy in Childhood High Risk Relapse of Acute Lymphoblastic Leukemia (Vandevol study of the French SFCE Acute Leukemia Committee).

Brigitte Nelken, MD, Guy Leverger, MD, Claire Galambrun, MD, Genevieve Plat, Claudine Schmitt, MD, Caroline Thomas, M.D., Cécile Vérité, MD, Benoit Brethon, MD, Virginie Gandemer, Yves Bertrand, André Baruchel, Pierre Rohrlich
Journal: Blood
Blood (2012) 120 (21): 2570.
https://doi.org/10.1182/blood.V120.21.2570.2570
Published: 2012