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Gerald de Haan
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Journal Articles

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

Arthur Flohr Svendsen, Daozheng Yang, KyungMok Kim, Seka Lazare, Natalia Skinder, Erik Zwart, Anna Mura-Meszaros, Albertina Ausema, Björn von Eyss, Gerald de Haan, Leonid Bystrykh
Journal: Blood
Blood (2021) 138 (6): 439–451.
https://doi.org/10.1182/blood.2020009729
Published: 2021
Includes: Supplemental data
Journal Articles

Aging of hematopoietic stem cells

Gerald de Haan, Seka Simone Lazare
Journal: Blood
Blood (2018) 131 (5): 479–487.
https://doi.org/10.1182/blood-2017-06-746412
Published: 2018
Journal Articles

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

Ana Martín-Pardillos, Anastasia Tsaalbi-Shtylik, Si Chen, Seka Lazare, Ronald P. van Os, Albertina Dethmers-Ausema, Nima Borhan Fakouri, Matthias Bosshard, Rossana Aprigliano, Barbara van Loon, Daniela C. F. Salvatori, Keiji Hashimoto, Celia Dingemanse-van der Spek, Masaaki Moriya, Lene Juel Rasmussen, Gerald de Haan, Marc H. G. P. Raaijmakers, Niels de Wind
Journal: Blood
Blood (2017) 130 (13): 1523–1534.
https://doi.org/10.1182/blood-2017-01-764274
Published: 2017
Includes: Supplemental data
Journal Articles

Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding

Mirjam E. Belderbos, Taco Koster, Bertien Ausema, Sabrina Jacobs, Sharlaine Sowdagar, Erik Zwart, Eveline de Bont, Gerald de Haan, Leonid V. Bystrykh
Journal: Blood
Blood (2017) 129 (24): 3210–3220.
https://doi.org/10.1182/blood-2016-12-758250
Published: 2017
Includes: Supplemental data
Journal Articles

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

Johannes Jung, MD, Hein Schepers, PhD, Seka Lazare, Sonja Buisman, Ellen Weersing, Bertien Dethmers, Karin Klauke, PhD, Lenja Bystrykh, PhD, Gerald De Haan, PhD
Journal: Blood
Blood (2016) 128 (22): 2651.
https://doi.org/10.1182/blood.V128.22.2651.2651
Published: 2016
Journal Articles

Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding

Evgenia Verovskaya, Mathilde J. C. Broekhuis, Erik Zwart, Martha Ritsema, Ronald van Os, Gerald de Haan, Leonid V. Bystrykh
Journal: Blood
Blood (2013) 122 (4): 523–532.
https://doi.org/10.1182/blood-2013-01-481135
Published: 2013
Includes: Supplemental data
Journal Articles

The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation

Marta A. Walasek, Leonid Bystrykh, Vincent van den Boom, Sandra Olthof, Albertina Ausema, Martha Ritsema, Gerwin Huls, Gerald de Haan, Ronald van Os
Journal: Blood
Blood (2012) 119 (13): 3050–3059.
https://doi.org/10.1182/blood-2011-08-375386
Published: 2012
Includes: Supplemental data
Journal Articles

Genetic screen identifies microRNA cluster 99b/let-7e/125a as a regulator of primitive hematopoietic cells

Alice Gerrits, Marta A. Walasek, Sandra Olthof, Ellen Weersing, Martha Ritsema, Erik Zwart, Ronald van Os, Leonid V. Bystrykh, Gerald de Haan
Journal: Blood
Blood (2012) 119 (2): 377–387.
https://doi.org/10.1182/blood-2011-01-331686
Published: 2012
Includes: Supplemental data
Journal Articles

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

Hein Schepers, Ph.D, Patrick M. Korthuis, Jan J. Schuringa, PhD, Gerald de Haan, Ph.D, Edo Vellenga, PhD
Journal: Blood
Blood (2011) 118 (21): 922.
https://doi.org/10.1182/blood.V118.21.922.922
Published: 2011
Journal Articles

Tracking Reconstitution Dynamics in Mice Co-Transplanted with Hematopoietic Stem Cells From Nine Distinguishable Donor Types

Brad Dykstra, PhD, Sulima Geerman, Jaring Schreuder, Martha Ritsema, Gerald De Haan, PhD
Journal: Blood
Blood (2011) 118 (21): 1890.
https://doi.org/10.1182/blood.V118.21.1890.1890
Published: 2011
Journal Articles

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34 + cells

Aleksandra Rizo, Sarah J. Horton, Sandra Olthof, Bert Dontje, Albertina Ausema, Ronald van Os, Vincent van den Boom, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa
Journal: Blood
Blood (2010) 116 (22): 4621–4630.
https://doi.org/10.1182/blood-2010-02-270660
Published: 2010
Includes: Supplemental data
Journal Articles

Effects of Age and Environment on Short-Term Homing and Function of Mouse Hematopoietic Stem Cells.

Brad Dykstra, PhD, Sandra Olthof, Martha Ritsema, Gerald De Haan, PhD
Journal: Blood
Blood (2010) 116 (21): 1616.
https://doi.org/10.1182/blood.V116.21.1616.1616
Published: 2010
Journal Articles

Cellular barcoding tool for clonal analysis in the hematopoietic system

Alice Gerrits, Brad Dykstra, Olga J. Kalmykowa, Karin Klauke, Evgenia Verovskaya, Mathilde J. C. Broekhuis, Gerald de Haan, Leonid V. Bystrykh
Journal: Blood
Blood (2010) 115 (13): 2610–2618.
https://doi.org/10.1182/blood-2009-06-229757
Published: 2010
Journal Articles

Repression of BMI1 in normal and leukemic human CD34 + cells impairs self-renewal and induces apoptosis

Aleksandra Rizo, Sandra Olthof, Lina Han, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa
Journal: Blood
Blood (2009) 114 (8): 1498–1505.
https://doi.org/10.1182/blood-2009-03-209734
Published: 2009
Journal Articles

Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1

Aleksandra Rizo, Bert Dontje, Edo Vellenga, Gerald de Haan, Jan Jacob Schuringa
Journal: Blood
Blood (2008) 111 (5): 2621–2630.
https://doi.org/10.1182/blood-2007-08-106666
Published: 2008
Includes: Supplemental data
Journal Articles

Ex-Vivo Expansion of Human Cord Blood CD34+ Cells by Overexpression of Bmi-1.

Aleksandra Rizo, MD, Edo Vellenga, MD,PhD, Gerald de Haan, PhD, Jan Jacob Schuringa, PhD
Journal: Blood
Blood (2006) 108 (11): 1329.
https://doi.org/10.1182/blood.V108.11.1329.1329
Published: 2006
Journal Articles

Unexpected Consequences of Sitosterolemia on Platelet Formation.

Lyndsay Drayer, PhD, Janine Kruit, PhD, Bert Dontje, Gerald de Haan, PhD, Ido Kema, PhD, Edo Vellenga, MD, PhD, Folkert Kuipers, PhD
Journal: Blood
Blood (2006) 108 (11): 1090.
https://doi.org/10.1182/blood.V108.11.1090.1090
Published: 2006
Journal Articles

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

Leonie M. Kamminga, Leonid V. Bystrykh, Aletta de Boer, Sita Houwer, José Douma, Ellen Weersing, Bert Dontje, Gerald de Haan
Journal: Blood
Blood (2006) 107 (5): 2170–2179.
https://doi.org/10.1182/blood-2005-09-3585
Published: 2006
Includes: Supplemental data
Journal Articles

Differential Role for VLA-5 in Mobilization of Heamotopoieic Stem Cells Toward Peripheral Blood and Homing to Bone Marrow and Spleen.

Pieter K. Wierenga, PhD, Ellen Weersing, Bert Dontje, Gerald de Haan, PhD, Ronald P. van Os, PhD
Journal: Blood
Blood (2005) 106 (11): 2190.
https://doi.org/10.1182/blood.V106.11.2190.2190
Published: 2005
Journal Articles

Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization

Ingo Roeder, Leonie M. Kamminga, Katrin Braesel, Bert Dontje, Gerald de Haan, Markus Loeffler
Journal: Blood
Blood (2005) 105 (2): 609–616.
https://doi.org/10.1182/blood-2004-01-0282
Published: 2005
Includes: Supplemental data