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Journal Articles

KPT-330 Combined with Radiation Therapy: Effective Central Nervous System Lymphoma Treatment with Reduced Neurotoxicity

Wenzhuo Zhuang, Yuchen Zhang, Chunxiao Yang, Linlin Qin, Ruijing Hu, Menglu Chen, Xinyuan Zhang, Qi Li, Xingping Lang, Si Chen, Bingzong Li

Blood (2024) 144 (Supplement 1): 958.

https://doi.org/10.1182/blood-2024-198290

Published: 2024

Journal Articles

Identification and Molecular Characterization of Endothelial Cells Associated with Hematopoietic Niche Formation in Humans Identifies IL-33 As an Anabolic Niche Factor

Keane Jared Guillaume Kenswil, BSc, MSc, Christopher Adrian Jaramillo, MD, Zhen Ping, MSc, Si Chen, MSc, Remco Michiel Hoogenboezem, MSc, Maria Athina Mylona, PhD, Maria Niken Adisty, BSc, Eric Moniqué Johannes Bindels, PhD, Hans Stoop, PhD, King Hong Lam, MD PhD, Pieter Koen Bos, MD, Bram van Eerden, PhD, Tom Cupedo, PhD, Marc Hermanus Gerardus Petrus Raaijmakers, MD PhD

Blood (2017) 130 (Supplement 1): 2437.

https://doi.org/10.1182/blood.V130.Suppl_1.2437.2437

Published: 2017

Journal Articles

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

Ana Martín-Pardillos, Anastasia Tsaalbi-Shtylik, Si Chen, Seka Lazare, Ronald P. van Os, Albertina Dethmers-Ausema, Nima Borhan Fakouri, Matthias Bosshard, Rossana Aprigliano, Barbara van Loon, Daniela C. F. Salvatori, Keiji Hashimoto, Celia Dingemanse-van der Spek, Masaaki Moriya, Lene Juel Rasmussen, Gerald de Haan, Marc H. G. P. Raaijmakers, Niels de Wind

Blood (2017) 130 (13): 1523–1534.

https://doi.org/10.1182/blood-2017-01-764274

Published: 2017

Includes: Supplemental data

Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Blood (2016) 128 (22): 428.

https://doi.org/10.1182/blood.V128.22.428.428

Published: 2016

Journal Articles

Minimal Residual Disease Assessment of Remission after Induction Therapy Is Superior to Morphologic Assessment for Risk Stratification in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group (COG)

Blood (2016) 128 (22): 758.

https://doi.org/10.1182/blood.V128.22.758.758

Published: 2016

Journal Articles

Incidence of Allergic Reactions to Pegaspargase (PEG) Administered Intramuscularly Versus Intravenously (IM vs. IV) in Children and Young Adults with High Risk B-Lymphoblastic Leukemia (HR B-ALL): Results of Children's Oncology Group (COG) Studies AALL0232/AALL1131

Wanda Salzer, MD, Michael J. Burke, MD, Eric C. Larsen, MD, Si Chen, MS, Lia Gore, MD, Joanne M. Hilden, MD, Mignon L. Loh, MD, Elizabeth Raetz, MD, Naomi J. Winick, MD, William L. Carroll, MD, Meenakshi Devidas, PhD, Stephen P Hunger, MD

Blood (2015) 126 (23): 1303.

https://doi.org/10.1182/blood.V126.23.1303.1303

Published: 2015

Journal Articles

Capizzi-Style Methotrexate with Pegasparagase (C-MTX) Is Superior to High-Dose Methotrexate (HDMTX) in T-Lineage Acute Lymphoblastic Leukemia (T-ALL): Results from Children's Oncology Group (COG) AALL0434

Stuart S. Winter, MD, Meenakshi Devidas, PhD, Si Chen, MS, Barbara Asselin, MD, William L. Carroll, MD, Brent L Wood, MD PhD, Natia Esiashvili, MD, Briegel J Nikki, PharmD, Robert J. Hayashi, MD, Mignon L. Loh, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Elizabeth Raetz, MD, Naomi J. Winick, MD, Stephen P. Hunger, MD, Kimberly P. Dunsmore, MD

Blood (2015) 126 (23): 794.

https://doi.org/10.1182/blood.V126.23.794.794

Published: 2015

Journal Articles

T-Lymphoblastic Leukemia (T-ALL) Shows Excellent Outcome, Lack of Significance of the Early Thymic Precursor (ETP) Immunophenotype, and Validation of the Prognostic Value of End-Induction Minimal Residual Disease (MRD) in Children’s Oncology Group (COG) Study AALL0434

Brent L. Wood, MD PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD, Meenakshi Devidas, PhD, Si Chen, Barbara Asselin, MD, Natia Esiashvili, MD, Mignon L. Loh, MD, Naomi J. Winick, MD, William L. Carroll, MD, Elizabeth A. Raetz, MD, Stephen P. Hunger, MD

Blood (2014) 124 (21): 1.

https://doi.org/10.1182/blood.V124.21.1.1

Published: 2014

Journal Articles

Effect of High-Dose Methotrexate (HD-MTX) Vs Capizzi Methotrexate/Pegaspargase (C-MTX/ASNase) on Osteonecrosis (ON) Incidence in Children and Young Adults with T-Acute Lymphoblastic Leukemia (T-ALL): Results of Children’s Oncology Group (COG) Study AALL0434

Leonard A. Mattano, MD, Meenakshi Devidas, PhD, Si Chen, MS, Natia Esiashvili, MD, Barbara Asselin, MD, Naomi J. Winick, MD, Mignon Loh, MD, Elizabeth A Raetz, MD, Stephen Hunger, MD, William L. Carroll, MD, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD

Blood (2014) 124 (21): 3649.

https://doi.org/10.1182/blood.V124.21.3649.3649

Published: 2014

Journal Articles

Inhibition of BCL11B Expression Leads to Apoptosis of Malignant T Cells but Not CD34 + Cells.

Xin Huang, Si Chen, Shaohua Chen, Lijian Yang, Qi Shen, Piotr Grabarczyk, Grzegorz K. Przybylski, Christian A. Schmidt, Yangqiu Li

Blood (2010) 116 (21): 3755.

https://doi.org/10.1182/blood.V116.21.3755.3755

Published: 2010

Journal Articles

The Regulation of Differentiation and Proliferation of the BCL11B Gene In T Cells

Si Chen, Shao-Hua Chen, Lijian Yang, Haitao Zheng, Xin Huang, Bo Li, Piotr Grabarczyk, Grzegorz K Przybylski, Christian A. Schmidt, Yangqiu Li

Blood (2010) 116 (21): 2769.

https://doi.org/10.1182/blood.V116.21.2769.2769

Published: 2010

Journal Articles

Effects of Down-Regulating BCL11B Expression On the Proliferation, Apoptosis and Global Gene Expression Profiling of Molt-4 Cells.

Xin Huang, Si Chen, Lijian Yang, Shao-Hua Chen, Yubing Zhou, Christian A. Schmidt, Yangqiu Li

Blood (2009) 114 (22): 4505.

https://doi.org/10.1182/blood.V114.22.4505.4505

Published: 2009

Journal Articles

Effects of down-Regulating BCL11B Expression on the Proliferation and Apoptosis of Molt-4 Cells by RNA Interference

Si Chen, Yangqiu Li, Xin Huang, Lijian Yang, Shaohua Chen, Yubing Zhou

Blood (2008) 112 (11): 4635.

https://doi.org/10.1182/blood.V112.11.4635.4635

Published: 2008

Journal Articles

The Feature of TCR Vβ Repertoire, Thymic Recent Output Function and TCR-zeta Chain Expression in Patients with Immune Thrombocytopenic Purpura.

Xueli Zhang, MA, Yangqiu Li, MD, Shaohua Chen, BA, Lijian Yang, Si Chen, BA, Xiuli Wu, PhD, Tao Zhang, BA, Jun Zhong, BA, Kanger Zhu, MA

Blood (2007) 110 (11): 2099.

https://doi.org/10.1182/blood.V110.11.2099.2099

Published: 2007

Journal Articles

The Feature of CD3-zeta Chain Gene Expression in Mononuclear Cells without and with Stimulation by Different Factors from Umbilical Cord Blood.

Shaohua Chen, BA, Yangqiu Li, MD, Lijian Yang, Si Chen, BA

Blood (2007) 110 (11): 3870.

https://doi.org/10.1182/blood.V110.11.3870.3870

Published: 2007

Journal Articles

Expression Pattern of TCR-zeta Chain in Patients with Aplastic Anemia and Polycythemia Vera.

Lijian Yang, Yangqiu Li, MD, Chuang Li, MA, Shaohua Chen, BA, Si Chen, BA, Chen Lin, MA

Blood (2007) 110 (11): 3763.

https://doi.org/10.1182/blood.V110.11.3763.3763

Published: 2007

Journal Articles

The Feature of TCR Zeta Gene in CD4+ and CD8+ T Cells in Patients with CML.

Si Chen, BA, Yangqiu Li, MD, Shaohua Chen, BA, Lijian Yang, Xiuli Wu, PhD, Dongzhi Cen, BA

Blood (2007) 110 (11): 4526.

https://doi.org/10.1182/blood.V110.11.4526.4526

Published: 2007

Journal Articles

The Feature of Distribution and Clonality of TCR Vα and Vβ Repertoire in Cord Blood.

Shaohua Chen, BA, Yangqiu Li, MD, Lijian Yang, Dongzhi Cen, BA, Si Chen, BA, Chuang Li, BA

Blood (2006) 108 (11): 5132.

https://doi.org/10.1182/blood.V108.11.5132.5132

Published: 2006

NARROW

KPT-330 Combined with Radiation Therapy: Effective Central Nervous System Lymphoma Treatment with Reduced Neurotoxicity

Identification and Molecular Characterization of Endothelial Cells Associated with Hematopoietic Niche Formation in Humans Identifies IL-33 As an Anabolic Niche Factor

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Minimal Residual Disease Assessment of Remission after Induction Therapy Is Superior to Morphologic Assessment for Risk Stratification in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group (COG)

Incidence of Allergic Reactions to Pegaspargase (PEG) Administered Intramuscularly Versus Intravenously (IM vs. IV) in Children and Young Adults with High Risk B-Lymphoblastic Leukemia (HR B-ALL): Results of Children's Oncology Group (COG) Studies AALL0232/AALL1131

Capizzi-Style Methotrexate with Pegasparagase (C-MTX) Is Superior to High-Dose Methotrexate (HDMTX) in T-Lineage Acute Lymphoblastic Leukemia (T-ALL): Results from Children's Oncology Group (COG) AALL0434

T-Lymphoblastic Leukemia (T-ALL) Shows Excellent Outcome, Lack of Significance of the Early Thymic Precursor (ETP) Immunophenotype, and Validation of the Prognostic Value of End-Induction Minimal Residual Disease (MRD) in Children’s Oncology Group (COG) Study AALL0434

Effect of High-Dose Methotrexate (HD-MTX) Vs Capizzi Methotrexate/Pegaspargase (C-MTX/ASNase) on Osteonecrosis (ON) Incidence in Children and Young Adults with T-Acute Lymphoblastic Leukemia (T-ALL): Results of Children’s Oncology Group (COG) Study AALL0434

Inhibition of BCL11B Expression Leads to Apoptosis of Malignant T Cells but Not CD34 + Cells.

The Regulation of Differentiation and Proliferation of the BCL11B Gene In T Cells

Effects of Down-Regulating BCL11B Expression On the Proliferation, Apoptosis and Global Gene Expression Profiling of Molt-4 Cells.

Effects of down-Regulating BCL11B Expression on the Proliferation and Apoptosis of Molt-4 Cells by RNA Interference

The Feature of TCR Vβ Repertoire, Thymic Recent Output Function and TCR-zeta Chain Expression in Patients with Immune Thrombocytopenic Purpura.

The Feature of CD3-zeta Chain Gene Expression in Mononuclear Cells without and with Stimulation by Different Factors from Umbilical Cord Blood.

Expression Pattern of TCR-zeta Chain in Patients with Aplastic Anemia and Polycythemia Vera.

The Feature of TCR Zeta Gene in CD4+ and CD8+ T Cells in Patients with CML.

The Feature of Distribution and Clonality of TCR Vα and Vβ Repertoire in Cord Blood.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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