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Journal Articles

Mertk Is a Therapeutic Target in Early T-Precursor Acute Lymphoblastic Leukemia

Ryan J Summers, MD, Katherine A Minson, MD, Stephen V Frye, PhD, Xiaodong Wang, PhD, H. Shelton Earp, III, MD, Deborah DeRyckere, PhD, Douglas K. Graham, MD PhD

Blood (2017) 130 (Supplement 1): 2536.

https://doi.org/10.1182/blood.V130.Suppl_1.2536.2536

Published: 2017

Journal Articles

MerTK Receptor Tyrosine Kinase Inhibition As a Potential Strategy to Augment Immune-Mediated Clearance of Acute Myeloid Leukemia

Lauren Shelby Page, BS, Xiaodong Wang, PhD, H. Shelton Earp, III, MD, Stephen Frye, PhD, Craig T Jordan, PhD, Alisa B. Lee-Sherick, MD

Blood (2016) 128 (22): 4044.

https://doi.org/10.1182/blood.V128.22.4044.4044

Published: 2016

Journal Articles

Bone Marrow Stromal Cell Mediated Resistance to Mertk Inhibition in Acute Leukemia

Katherine A Minson, MD, Madeline G Huey, BS, Amanda A Hill, Irene Perez, Xiaodong Wang, PhD, Stephen Frye, PhD, H. Shelton Earp, III, MD, Deborah DeRyckere, PhD, Douglas K. Graham, MD PhD

Blood (2016) 128 (22): 2819.

https://doi.org/10.1182/blood.V128.22.2819.2819

Published: 2016

Journal Articles

Mer Receptor Tyrosine Kinase Is a Novel Therapeutic Target In Multiple Myeloma

Sandra Christoph, Silke Maag, Deborah DeRyckere, Douglas K. Graham, MD, PhD, Stephen V Frye, H. Shelton Earp, III, Jing Liu, Chao Yang, Weihe Zhang, Xiaodong Wang, Ahmet H. Elmaagacli, Dietrich Beelen, MD

Blood (2013) 122 (21): 1957.

https://doi.org/10.1182/blood.V122.21.1957.1957

Published: 2013

Journal Articles

Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Mediate Synergistic Inhibition Of Platelet Aggregation In Combination With ADP/P2Y Antagonists

Gilbert Acevedo, BS, Brian R. Branchford, MD, Luke Law, BS, Christine Brzezinski, Susan Sather, Gary Brodsky, PhD, Deborah DeRyckere, Ph.D., Weihe Zhang, H. Shelton Earp, III, Stephen V Frye, Douglas K. Graham, MD, PhD, Jorge Di Paola, MD

Blood (2013) 122 (21): 3507.

https://doi.org/10.1182/blood.V122.21.3507.3507

Published: 2013

Journal Articles

Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Inhibit Platelet Aggregation In Vitro and Protect Mice From Arterial and Venous Thrombosis In Vivo

Gilbert Acevedo, BS, Brian R. Branchford, MD, Christine Brzezinski, Susan Sather, Gary Brodsky, PhD, Deborah DeRyckere, Ph.D., Weihe Zhang, Jing Liu, H. Shelton Earp, III, Xiaodong Wang, Stephen V Frye, Douglas K. Graham, MD, PhD, Jorge Di Paola, MD

Blood (2013) 122 (21): 2296.

https://doi.org/10.1182/blood.V122.21.2296.2296

Published: 2013

Journal Articles

UNC1666, a Dual Mer and Flt-3 Tyrosine Kinase Small Molecule Inhibitor In Acute Myeloid Leukemia

Alisa B. Lee-Sherick, MD, Kelly Menachof, Amanda A Hill, Sean Rinella, MPH, Jing Liu, Deborah DeRyckere, Xiaodong Wang, Stephen V Frye, H. Shelton Earp, III, Douglas K. Graham, MD, PhD

Blood (2013) 122 (21): 3849.

https://doi.org/10.1182/blood.V122.21.3849.3849

Published: 2013

Journal Articles

Development Of a Novel Small Molecule Inhibitor Of The Mer Tyrosine Kinase For Treatment Of Acute Lymphoblastic Leukemia

Deborah DeRyckere, Xiaodong Wang, Amanda A Hill, Weihe Zhang, Michael A Stashko, Susan Sather, Christopher E Cummings, William P Janzen, Stephen V Frye, H. Shelton Earp, III, Douglas K. Graham, MD, PhD

Blood (2013) 122 (21): 2666.

https://doi.org/10.1182/blood.V122.21.2666.2666

Published: 2013

Journal Articles

Mer Receptor Tyrosine Kinase Is A Potential Therapeutic Target in Acute Myeloid Leukemia

Alisa B. Lee-Sherick, MD, Kelly Menachof, Kristen M. Eisenman, MD, Amy McGranahan, Colleen McGary, Sally A. Hunsucker, PhD, Jennifer Schlegel, Paul M Armistead, MD, PhD, Xiayuan Liang, MD, Dmitri Kireev, William Janzen, Jing Liu, Michael Stashko, Jacqueline Norris-Drouin, H. Shelton Earp, III, Xiaodong Wang, Stephen Frye, Deborah DeRyckere, PhD, Douglas K. Graham, MD, PhD

Blood (2012) 120 (21): 1317.

https://doi.org/10.1182/blood.V120.21.1317.1317

Published: 2012

Journal Articles

A Small Molecule Inhibitor of the Gas6/Mer Pathway Inhibits Platelet Activation and Thrombosis with Equal Efficacy to, but Greater Potency Than, iMer, the Novel MerTK Splice Variant

Brian R. Branchford, MD, Luke Law, BS, Susan Sather, BS, Gary Brodsky, PhD, H. Shelton Earp, III, Xiaodong Wang, Stephen Frye, Douglas K. Graham, MD, PhD, Jorge A Di Paola, MD

Blood (2012) 120 (21): 3303.

https://doi.org/10.1182/blood.V120.21.3303.3303

Published: 2012

Journal Articles

Evaluation of UNC569, a Novel Small Molecule Mer Inhibitor for the Treatment of ALL in Vitro and in Vivo.

Sandra Christoph, Deborah DeRyckere, PhD, Jennifer Schlegel, Susan Sather, BS, Amy McGranahan, J. Kimble Franzer, Alesia Trakhimets, Xiaodong Wang, Dmitri Kireev, William Janzen, Jing Liu, Chao Yang, Catherine Simpson, Jacqueline Norris-Drouin, Stephen Frye, H. Shelton Earp, III, Gary L. Johnson, Douglas K. Graham

Blood (2012) 120 (21): 2607.

https://doi.org/10.1182/blood.V120.21.2607.2607

Published: 2012

Journal Articles

UNC569 As Novel Small Molecule Mer Receptor Tyrosine Kinase Inhibitor for Treatment of ALL

Sandra Christoph, Deborah DeRyckere, PhD, Susan Sather, BS, Xiaodong Wang, Dmitri Kireev, William Janzen, Jing Liu, Chao Yang, Amy van Deusen, Catherine Simpson, Jacqueline Norris-Drouin, Stephen Frye, H. Shelton Earp, III, Gary L. Johnson, Douglas K. Graham

Blood (2011) 118 (21): 2589.

https://doi.org/10.1182/blood.V118.21.2589.2589

Published: 2011

Journal Articles

Disruption of GAS6-MER Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages

Linda Kadi, Laurent Burnier, Rocco Sugamele, Peter Carmeliet, Greg Lemke, H. Shelton Earp, III, Glenn K. Matsushima, Marc Schapira, Anne Angelillo-Scherrer

Blood (2008) 112 (11): 499.

https://doi.org/10.1182/blood.V112.11.499.499

Published: 2008

NARROW

Mertk Is a Therapeutic Target in Early T-Precursor Acute Lymphoblastic Leukemia

MerTK Receptor Tyrosine Kinase Inhibition As a Potential Strategy to Augment Immune-Mediated Clearance of Acute Myeloid Leukemia

Bone Marrow Stromal Cell Mediated Resistance to Mertk Inhibition in Acute Leukemia

Mer Receptor Tyrosine Kinase Is a Novel Therapeutic Target In Multiple Myeloma

Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Mediate Synergistic Inhibition Of Platelet Aggregation In Combination With ADP/P2Y Antagonists

Novel Small Molecule Inhibitors Of The Gas6/TAM Signaling Pathway Inhibit Platelet Aggregation In Vitro and Protect Mice From Arterial and Venous Thrombosis In Vivo

UNC1666, a Dual Mer and Flt-3 Tyrosine Kinase Small Molecule Inhibitor In Acute Myeloid Leukemia

Development Of a Novel Small Molecule Inhibitor Of The Mer Tyrosine Kinase For Treatment Of Acute Lymphoblastic Leukemia

Mer Receptor Tyrosine Kinase Is A Potential Therapeutic Target in Acute Myeloid Leukemia

A Small Molecule Inhibitor of the Gas6/Mer Pathway Inhibits Platelet Activation and Thrombosis with Equal Efficacy to, but Greater Potency Than, iMer, the Novel MerTK Splice Variant

Evaluation of UNC569, a Novel Small Molecule Mer Inhibitor for the Treatment of ALL in Vitro and in Vivo.

UNC569 As Novel Small Molecule Mer Receptor Tyrosine Kinase Inhibitor for Treatment of ALL

Disruption of GAS6-MER Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages

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American Society of Hematology

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American Society of Hematology

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