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Journal Articles

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

Mohamad Jawhar, MD, Juliana Schwaab, MD, Manja Meggendorfer, PhD, Nicole Naumann, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Karla Schmitt, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD, Andreas Reiter, MD

Blood (2016) 128 (22): 3109.

https://doi.org/10.1182/blood.V128.22.3109.3109

Published: 2016

Journal Articles

SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish

Blood (2016) 128 (22): 2.

https://doi.org/10.1182/blood.V128.22.2.2

Published: 2016

Journal Articles

Impact of Molecular Markers on Response and Resistance in Midostaurin-Treated Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Juliana Schwaab, MD, Nicole Naumann, Sebastian Kluger, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Georgia Metzgeroth, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Manja Meggendorfer, PhD, Andreas Reiter, MD

Blood (2016) 128 (22): 945.

https://doi.org/10.1182/blood.V128.22.945.945

Published: 2016

Journal Articles

Incidence and Prognostic Impact of Cytogenetics in Combination with Molecular Aberrations in Patients with Systemic Mastocytosis

Nicole Naumann, Mohamad Jawhar, MD, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Henning D Popp, MD, Nada Khaled, MD, Hans-Peter Horny, MD, Karl Sotlar, MD, Peter Valent, MD, Claudia Haferlach, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, Prof, MD, Manja Meggendorfer, PhD, Nicholas C.P. Cross, PhD, Wolf-Karsten Hofmann, MD, Andreas Reiter, MD, Alice Fabarius, PhD

Blood (2016) 128 (22): 947.

https://doi.org/10.1182/blood.V128.22.947.947

Published: 2016

Journal Articles

A Human Bone Marrow Failure Syndrome Caused By a Homozygous Mutation in MYSM1

Ehsan Bahrami, Tomas Racek, PhD, Maximilian Witzel, MD, Jacek Puchalka, PhD, Naschla Greif-Kohistani, MD, Daniel Kotlarz, MD PhD, Michael Orth, PhD, Kirsten Lauber, PhD, Christoph Walz, MD, Waleed Al Herz, MD, Hans-Peter Horny, MD, Heinrich Schmidt, MD, Michael H. Albert, MD, Christoph Klein, MD PhD

Blood (2015) 126 (23): 1204.

https://doi.org/10.1182/blood.V126.23.1204.1204

Published: 2015

Journal Articles

Additional Mutations in SRSF2, ASXL1 and/or RUNX1 Identify a High Risk Group of Patients with KIT D816V + Advanced Systemic Mastocytosis

Mohamad Jawhar, Juliana Schwaab, MD, Susanne Schnittger, PhD, Manja Meggendorfer, PhD, Karl Sotlar, MD, Hans-Peter Horny, MD, Georgia Metzgeroth, MD, Sebastian Kluger, Nicole Naumann, Claudia Haferlach, MD, Torsten Haferlach, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Alice Charlotte Fabarius, PhD, Nicholas C.P. Cross, PhD, Andreas Reiter, MD

Blood (2015) 126 (23): 349.

https://doi.org/10.1182/blood.V126.23.349.349

Published: 2015

Journal Articles

Molecular Profiling of Myeloid Progenitor Cells in Multi-Mutated Advanced Systemic Mastocytosis Identifies KIT D816V As a Distinct and Late Event

Mohamad Jawhar, MD, Juliana Schwaab, MD, Susanne Schnittger, PhD, Karl Sotlar, MD, Hans Peter Horny, MD, Georgia Metzgeroth, Sven Schneider, MD, Nadine Müller, Nicole Naumann, Christoph Walz, MD, Torsten Haferlach, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD

Blood (2014) 124 (21): 3216.

https://doi.org/10.1182/blood.V124.21.3216.3216

Published: 2014

Journal Articles

Midostaurin (PKC412) Demonstrates a High Rate of Durable Responses in Patients with Advanced Systemic Mastocytosis: Results from the Fully Accrued Global Phase 2 CPKC412D2201 Trial

Jason Gotlib, MD MS, Hanneke C. Kluin-Nelemans, MD PhD, Tracy I. George, MD, Cem Akin, MD PhD, Karl Sotlar, MD, Olivier Hermine, MD PhD, Farrukh Awan, MD MS, Elizabeth O Hexner, MD, Michael Mauro, MD, David Sternberg, MD PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, Eric Stanek, PharmD, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2014) 124 (21): 636.

https://doi.org/10.1182/blood.V124.21.636.636

Published: 2014

Journal Articles

Bromodomain-Containing Protein 4 (BRD4): A Novel Marker and Drug Target Expressed In Neoplastic Cells In Advanced Mast Cell Neoplasms

Ghaith Wedeh, Emir Hadzijusufovic, DVM, Sabine Cerny-Reiterer, D.V.M, Harald Herrmann, M.D., Katharina Blatt, MSc, Ph.D., Gregor Eisenwort, M.D., Ph.D, Gregor Hoermann, M.D., Ph.D., Wolfgang R Sperr, M.D., Leonhard Müllauer, M.D., Christopher R. Vakoc, M.D., Ph.D., James E Bradner, MD, Hans-Peter Horny, MD, Michael Willmann, D.V.M., Johannes Zuber, MD, Michel Arock, PharmD, Ph.D, Peter Valent

Blood (2013) 122 (21): 3747.

https://doi.org/10.1182/blood.V122.21.3747.3747

Published: 2013

Journal Articles

Identification Of The Ki-1 Antigen (CD30) As a Novel Marker and Potential Therapeutic Target In Neoplastic Mast Cells In Advanced Systemic Mastocytosis

Katharina Blatt, MSc, Ph.D., Sabine Cerny-Reiterer, D.V.M, Karl Sotlar, M.D., Schwaab Juliana, M.D., Gregor Hoermann, M.D., Ph.D., Matthias Mayerhofer, M.D., Emir Hadzijusufovic, DVM, Michael Willmann, D.V.M., Andreas Reiter, MD, Hans-Peter Horny, MD, Peter Valent

Blood (2013) 122 (21): 3773.

https://doi.org/10.1182/blood.V122.21.3773.3773

Published: 2013

Journal Articles

Durable Responses and Improved Quality Of Life With Midostaurin (PKC412) In Advanced Systemic Mastocytosis (SM): Updated Stage 1 Results Of The Global D2201 Trial

Jason Gotlib, MD, Hanneke C. Kluin-Nelemans, MD, PhD, Tracy I. George, MD, Cem Akin, MD, PhD, Karl Sotlar, MD, Olivier Hermine, Farrukh Awan, MD, MS, Elizabeth Hexner, MD, Michael Mauro, MD, Rodica Morariu, MD, Margaret Squier, MD, PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, John Coombs, PharmD, MBA, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2013) 122 (21): 106.

https://doi.org/10.1182/blood.V122.21.106.106

Published: 2013

Journal Articles

Mutational Complexity Is Related To Disease Severity In Systemic Mastocytosis

Blood (2013) 122 (21): 4094.

https://doi.org/10.1182/blood.V122.21.4094.4094

Published: 2013

Journal Articles

The KIT D816V Allele Burden in Systemic Mastocytosis Is Strongly Associated with Disease Subtype.

Juliana Schwaab, MD, Philipp Erben, MD, Hans-Peter Horny, MD, Martina Teichmann, MD, Georgia Metzgeroth, MD, Thomas Ernst, MD, Karl Sotlar, MD, Martin C Mueller, MD, Alexander Marx, MD, Karin Hartmann, MD, Andreas Hochhaus, MD, Nicholas C.P. Cross, PhD, Wolf Karsten Hofmann, MD, PhD, Andreas Reiter, MD

Blood (2012) 120 (21): 2859.

https://doi.org/10.1182/blood.V120.21.2859.2859

Published: 2012

Journal Articles

KIT Inhibitor Midostaurin in Patients with Advanced Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global CPKC412D2201 Trial

Jason Gotlib, MD, MS, Hanneke C. Kluin-Nelemans, MD, PhD, Tracy I. George, MD, Cem Akin, MD, PhD, Karl Sotlar, MD, Olivier Hermine, MD, PhD, Farrukh Awan, MD, MS, Elizabeth Hexner, MD, Michael J. Mauro, MD, Rodica Morariu, MD, Margaret Squier, MD, PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2012) 120 (21): 799.

https://doi.org/10.1182/blood.V120.21.799.799

Published: 2012

Journal Articles

Critical Evaluation of Diverse Clinical, Laboratory, Radiological and Histological Parameters Indicating Gastrointestinal Involvement for Diagnosis of Indolent and Aggressive Systemic Mastocytosis

Georgia Metzgeroth, MD, Juliana Schwaab, MD, Martina Teichmann, MD, Alexander Marx, MD, Henrik J. Michaely, MD, Hans Peter Horny, MD, Nicholas C.P. Cross, PhD, Andreas Hochhaus, MD, Wolf Karsten Hofmann, MD, PhD, Andreas Reiter, MD

Blood (2011) 118 (21): 5159.

https://doi.org/10.1182/blood.V118.21.5159.5159

Published: 2011

Journal Articles

KIT D816V and JAK2 V617F Point Mutations Are Recurrently Found In Suspected Hypereosinophilic Syndrome

Juliana Popa, MD, Philipp Erben, MD, Georgia Metzgeroth, MD, Georg Bolz, MD, Martin C Mueller, MD, Christoph Walz, MD, Hans Peter Horny, MD, Philipp Ströbel, MD, Alexander Marx, MD, Nicholas C.P. Cross, PhD, FRCPath, Andreas Hochhaus, Wolf-Karsten Hofmann, MD, Andreas Reiter, MD

Blood (2010) 116 (21): 4100.

https://doi.org/10.1182/blood.V116.21.4100.4100

Published: 2010

Journal Articles

c-kit D816V Provides a Strong Signal for Myelomastocytic Differentiation and Cluster Formation in Murine Ba/F3 Cells.

Matthias Mayerhofer, MD, Karl J. Aichberger, MD, Stefan Florian, Maria-Theresa Krauth, MD, Martin Bilban, PhD, Harald Esterbauer, MD, PhD, Oswald Wagner, MD, Reinhard Kodym, MD, Karl Sotlar, MD, Jack B. Longley, MD, Hans-Peter Horny, MD, Christian Sillaber, MD, Peter Valent, MD

Blood (2004) 104 (11): 485.

https://doi.org/10.1182/blood.V104.11.485.485

Published: 2004

NARROW

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish

Impact of Molecular Markers on Response and Resistance in Midostaurin-Treated Patients with Advanced Systemic Mastocytosis

Incidence and Prognostic Impact of Cytogenetics in Combination with Molecular Aberrations in Patients with Systemic Mastocytosis

A Human Bone Marrow Failure Syndrome Caused By a Homozygous Mutation in MYSM1

Additional Mutations in SRSF2, ASXL1 and/or RUNX1 Identify a High Risk Group of Patients with KIT D816V + Advanced Systemic Mastocytosis

Molecular Profiling of Myeloid Progenitor Cells in Multi-Mutated Advanced Systemic Mastocytosis Identifies KIT D816V As a Distinct and Late Event

Midostaurin (PKC412) Demonstrates a High Rate of Durable Responses in Patients with Advanced Systemic Mastocytosis: Results from the Fully Accrued Global Phase 2 CPKC412D2201 Trial

Bromodomain-Containing Protein 4 (BRD4): A Novel Marker and Drug Target Expressed In Neoplastic Cells In Advanced Mast Cell Neoplasms

Identification Of The Ki-1 Antigen (CD30) As a Novel Marker and Potential Therapeutic Target In Neoplastic Mast Cells In Advanced Systemic Mastocytosis

Durable Responses and Improved Quality Of Life With Midostaurin (PKC412) In Advanced Systemic Mastocytosis (SM): Updated Stage 1 Results Of The Global D2201 Trial

Mutational Complexity Is Related To Disease Severity In Systemic Mastocytosis

The KIT D816V Allele Burden in Systemic Mastocytosis Is Strongly Associated with Disease Subtype.

KIT Inhibitor Midostaurin in Patients with Advanced Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global CPKC412D2201 Trial

Critical Evaluation of Diverse Clinical, Laboratory, Radiological and Histological Parameters Indicating Gastrointestinal Involvement for Diagnosis of Indolent and Aggressive Systemic Mastocytosis

KIT D816V and JAK2 V617F Point Mutations Are Recurrently Found In Suspected Hypereosinophilic Syndrome

c-kit D816V Provides a Strong Signal for Myelomastocytic Differentiation and Cluster Formation in Murine Ba/F3 Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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