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Harsimran Kaur
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Journal Articles

Replicative stress-induced aging of hematopoietic stem progenitor cells increases oncogenic mutation burden and incidence of myelodysplasia in sickle cell disease mice

Free
Mengna Chi, Fabienne Lucas, Ammar Husami, Tahereh Setayesh, Zhenqi Zhu, Harsimran Kaur, Anifat Tijani, Shristi Khanal, Jing Chen, Wenying Zhang, Punam Malik
Journal: Blood
Blood (2025) 146 (Supplement 1): 11.
https://doi.org/10.1182/blood-2025-11
Published: 2025
Journal Articles

Oxidative stress and hemoglobin-c denaturation drive hemoglobin SC pathophysiology and can be ameliorated by antioxidants and hydroxyurea

Free
Tahereh Setayesh, Anifat Tijani, Harsimran Kaur, Shristi Khanal, Zhenqi Zhu, Mengna Chi, Abigail Kincaid, Russell Ware, Punam Malik
Journal: Blood
Blood (2025) 146 (Supplement 1): 7.
https://doi.org/10.1182/blood-2025-7
Published: 2025
Journal Articles

A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea

Open Access
Tahereh Setayesh, Mengna Chi, Zachery Oestreicher, Masahide Sakabe, Katie Seu, Zhenqi Zhu, Harsimran Kaur, Anifat Tijani, Mei Xin, Amy Shova, Kenneth D. Greis, Tim M. Townes, József Balla, Katherine VandenHeuvel, Yueh-Chiang Hu, Punam Malik
Journal: Blood
Blood (2025) 146 (1): 13–28.
https://doi.org/10.1182/blood.2024028136
Published: 2025
Includes: Supplemental data