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Hartmut Koeppen
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Journal Articles

Loss of CD20 expression as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas

Clinical Trials & Observations
Stephen J. Schuster, Ling-Yuh Huw, Christopher R. Bolen, Victor Maximov, Andrew G. Polson, Katerina Hatzi, Elisabeth A. Lasater, Sarit E. Assouline, Nancy L. Bartlett, L. Elizabeth Budde, Matthew J. Matasar, Hartmut Koeppen, Emily C. Piccione, Deanna Wilson, Michael C. Wei, Shen Yin, Elicia Penuel
Journal: Blood
Blood (2024) 143 (9): 822–832.
https://doi.org/10.1182/blood.2023022348
Published: 2024
Includes: Supplemental data
Journal Articles

Early Pharmacodynamic Changes in T-Cell Activation, Proliferation, and Cytokine Production Confirm the Mode of Action of BFCR4350A, a FcRH5/CD3 T-Cell-Engaging Bispecific Antibody, in Patients with Relapsed/Refractory Multiple Myeloma

Rin Nakamura, Sean Lear, Deanna Wilson, Hartmut Koeppen, Anjali Vaze, Suzanne Trudel, MD MSC, FRCPC, Andrew Spencer, Simon J Harrison, MBBS MRCP (UK) PhDFRCPath (UK) FRACP, Adam D. Cohen, MD, Bernard M Fine, Mengsong Li, James Cooper, Teiko Sumiyoshi
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-136980
Published: 2020
Journal Articles

Pharmacodynamic Effects and Immune Correlates of Response to the CD20/CD3 Bispecific Antibody Mosunetuzumab in Relapsed or Refractory Non-Hodgkin Lymphoma

Genevive Hernandez, PhD, Ling-Yuh Huw, PhD, Anton Belousov, PhD, Deanna Wilson, MS, Hartmut Koeppen, MD PhD, Ron McCord, PhD, Kun Peng, PhD, Nancy L Bartlett, MD, Lihua E Budde, MD PhD, Sarit Assouline, MD, Loretta J. Nastoupil, MD MSc, Dok Hyun Yoon, MD PhD, Matthew J Matasar, MD, Brendan Bender, PhD, Antonia Kwan, MD PhD MRCPCH, Chi-Chung Li, PhD, Carol O'Hear, MD PhD, Shen Yin, PhD, Michael C Wei, MD PhD, Joanne I Adamkewicz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1585.
https://doi.org/10.1182/blood-2019-123933
Published: 2019
Journal Articles

High Expression of Programmed Death-Ligand 1 (PD-L1) Correlates with Macrophage Gene Expression and Is Associated with Prolonged Progression-Free Survival (PFS) in Patients (pts) with First-Line (1L) Diffuse Large B-Cell Lymphoma (DLBCL)

Ronald McCord, Christopher Bolen, Hartmut Koeppen, Edward E. Kadel, III, Günter Fingerle-Rowson, Mikkel Z. Oestergaard, Jeffrey M. Venstrom
Journal: Blood
Blood (2017) 130 (Supplement 1): 195.
https://doi.org/10.1182/blood.V130.Suppl_1.195.195
Published: 2017
Journal Articles

CD40 Pathway Activation Status Predicts Response to CD40 Targeted Therapy in Diffuse Large b-Cell Lymphoma.

David Dornan, Ph.D, Bart Burington, Ph.D, Peng Yue, Ph.D, Xiaoyan Shi, Ph.D, Ranjana Advani, MD, Nancy Yu, Jeffrey T Lau, Shang-Fan Yu, Sven De Vos, MD, PhD, Stephen M Ansell, Andres Forero-Torres, MD, Zora Modrusan, Hartmut Koeppen, Teddy Yang, Changchun Du, BM, BS, Kristi Elkins, Andrew G. Polson, Rienk Offringa, Nancy Whiting, PharmD, BCOP, Allen J. Ebens, PhD
Journal: Blood
Blood (2009) 114 (22): 2721.
https://doi.org/10.1182/blood.V114.22.2721.2721
Published: 2009
Journal Articles

Therapeutic potential of an anti-CD79b antibody–drug conjugate, anti–CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma

David Dornan, Fiona Bennett, Yvonne Chen, Mark Dennis, Dan Eaton, Kristi Elkins, Dorothy French, Mary Ann T. Go, Andrew Jack, Jagath R. Junutula, Hartmut Koeppen, Jeffrey Lau, Jacqueline McBride, Andy Rawstron, Xiaoyan Shi, Nancy Yu, Shang-Fan Yu, Peng Yue, Bing Zheng, Allen Ebens, Andrew G. Polson
Journal: Blood
Blood (2009) 114 (13): 2721–2729.
https://doi.org/10.1182/blood-2009-02-205500
Published: 2009
Includes: Supplemental data
Journal Articles

Development and Therapeutic Potential of an Anti-CD79b Antibody-Drug Conjugate, Anti-CD79b-Vc-MMAE, for the Treatment of Non-Hodgkin’s Lymphoma

Andrew G. Polson, Fiona L Bennett, Yvonne Chen, Mark Dennis, Dan Eaton, Allen Ebens, Kristi Elkins, Dorothy French, Mary Ann T. Go, Andrew S Jack, Jagath Junutula, Hartmut Koeppen, Jeffery Lau, Jacqueline McBride, Lily Shi, Andy Rawston, Shang-Fan Yu, Peng Yue, Bing Zheng, David Dornan
Journal: Blood
Blood (2008) 112 (11): 2618.
https://doi.org/10.1182/blood.V112.11.2618.2618
Published: 2008
Journal Articles

Antibody-Drug Conjugates with Uncleavable Linkers for the Treatment of Non-Hodgkin Lymphoma.

Andrew G. Polson, PhD, Suzanna Clark, Changchun Du, Dan Eaton, Ph.D., Kristi Elkins, Reina N. Fuji, VMD, PhD, Mary Ann, Go, Alane Gray, Tom Januario, Hartmut Koeppen, M.D., Ph.D., Jeffery Lau, Will Leach, Elena McDorman, Ph.D., Kathleen McKeever, Ph.D., Saileta Prabhu, Ph.D., Suzie J. Scales, Ph.D., Dionysos Slaga, Susan Spencer, Marna Williams, Ph.D, David Xie, Shang-Fan Yu, Bing Zheng, Allen Ebens, PhD.
Journal: Blood
Blood (2007) 110 (11): 526.
https://doi.org/10.1182/blood.V110.11.526.526
Published: 2007