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Helen Sabzevari
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Journal Articles

Phase 1/1b Safety Study of Prgn-3006 Ultracar-T in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

David A. Sallman, Hany Elmariah, Kendra Sweet, Asmita Mishra, Cheryl A Cox, Marion Chakaith, Roshanak Semnani, Sheeba Shehzad, Asha Anderson, Helen Sabzevari, Amy Lankford, Onyee Chan, Luis SanchezMolina, Chen Wang, Eric Padron, Andrew Kuykendall, Rami S. Komrokji, Jeffrey E. Lancet, Marco L. Davila, Nelli Bejanyan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10313–10315.
https://doi.org/10.1182/blood-2022-169142
Published: 2022
Journal Articles

A Phase1/1b Dose Escalation/Dose Expansion Study of Prgn-3007 Ultracar-T Cells in Patients with Advanced Hematologic and Solid Tumor Malignancies

Javier Pinilla Ibarz, Amy Lankford, Helen Sabzevari, Bijal D. Shah, Hatem Soliman, Julio C. Chavez, Rutul R Shah
Journal: Blood
Blood (2022) 140 (Supplement 1): 7486–7487.
https://doi.org/10.1182/blood-2022-168932
Published: 2022
Journal Articles

Preclinical Evaluation of Prgn-3007, a Non-Viral, Multigenic, Autologous ROR1 Ultracar-T ® Therapy with Novel Mechanism of Intrinsic PD-1 Blockade for Treatment of Hematological and Solid Cancers

Tim Chan, Sean P Scott, Mengyan Du, Cheryl Bolinger, Carol Poortman, Lindsey Shepard, Byron Koenitzer, Adeline Govekung, Carlos Sailor, Rahim Johnson, Jacques Plummer, Steven Zilko, Shourik Dutta, Kannan Kunchithapautham, Taranjit Athwal, Bernward Klocke, Christian Zinser, Maha Abdeladhim, Shamim Ahmad, Simon Metenou, Roshanak Semnani, Douglas E Brough, Rutul R Shah, Helen Sabzevari
Journal: Blood
Blood (2021) 138 (Supplement 1): 1694.
https://doi.org/10.1182/blood-2021-149203
Published: 2021
Journal Articles

Phase 1/1b Safety Study of Prgn-3006 Ultracar-T in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

David A. Sallman, Hany Elmariah, Kendra Sweet, Chetasi Talati, Asmita Mishra, Cheryl A Cox, Roshanak Semnani, Rutul R Shah, Helen Sabzevari, Marion Chakiath, Justin Uthuppan, Amy Lankford, Chen Wang, Eric Padron, Andrew T. Kuykendall, Rami S. Komrokji, Jeffrey E. Lancet, Marco L. Davila, Nelli Bejanyan
Journal: Blood
Blood (2021) 138 (Supplement 1): 825.
https://doi.org/10.1182/blood-2021-152692
Published: 2021
Journal Articles

A Phase 1/1b Safety Study of Prgn-3006 Ultracar-T™ in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome

David A. Sallman, MD, Hany Elmariah, MD MS, Kendra L. Sweet, MD MS, Chetasi Talati, MD, Asmita Mishra, MD, Linda L. Kelley, PhD, Amy Lankford, PhD, Tim Chan, PhD, Rutul R Shah, Eric Padron, MD, Rami S. Komrokji, MD, Jeffrey E. Lancet, MD, Helen Sabzevari, PhD, Marco L. Davila, MD PhD, Nelli Bejanyan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-139417
Published: 2020
Journal Articles

Preclinical Characterization of Prgn-3006 Ultracar-T™ for the Treatment of AML and MDS: Non-Viral, Multigenic Autologous CAR-T Cells Administered One Day after Gene Transfer

Tim Chan, PhD, Xiaohong Ma, Fernando Carvajal-Borda, DVM, Jose Velez, Jacques Plummer, Lindsey Shepard, Rutul R Shah, David A Sallman, MD, Helen Sabzevari, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2660.
https://doi.org/10.1182/blood-2019-130617
Published: 2019
Journal Articles

Development of an IL-15–autocrine CD8 T-cell leukemia in IL-15–transgenic mice requires the cis expression of IL-15Rα

Noriko Sato, Helen Sabzevari, Song Fu, Wei Ju, Michael N. Petrus, Richard N. Bamford, Thomas A. Waldmann, Yutaka Tagaya
Journal: Blood
Blood (2011) 117 (15): 4032–4040.
https://doi.org/10.1182/blood-2010-09-307504
Published: 2011
Includes: Supplemental data
Journal Articles

Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites

Roshanak Tolouei Semnani, Priyanka Goel Venugopal, Cynthia A. Leifer, Sven Mostböck, Helen Sabzevari, Thomas B. Nutman
Journal: Blood
Blood (2008) 112 (4): 1290–1298.
https://doi.org/10.1182/blood-2008-04-149856
Published: 2008
Journal Articles

Acquisition of antigen presentasome (APS), an MHC/costimulatory complex, is a checkpoint of memory T-cell homeostasis

Sven Mostböck, Marta Catalfamo, Yutaka Tagaya, Jeffrey Schlom, Helen Sabzevari
Journal: Blood
Blood (2006) 109 (6): 2488–2495.
https://doi.org/10.1182/blood-2006-09-047290
Published: 2006
Journal Articles

Physiological relevance of antigen presentasome (APS), an acquired MHC/costimulatory complex, in the sustained activation of CD4 + T cells in the absence of APCs

Jun Zhou, Yutaka Tagaya, Roshanak Tolouei-Semnani, Jeffrey Schlom, Helen Sabzevari
Journal: Blood
Blood (2005) 105 (8): 3238–3246.
https://doi.org/10.1182/blood-2004-08-3236
Published: 2005
Includes: Supplemental data
Journal Articles

Inhibition of CD4 + 25 + T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

M. E. Christine Lutsiak, Roshanak T. Semnani, Roberto De Pascalis, Syed V. S. Kashmiri, Jeffrey Schlom, Helen Sabzevari
Journal: Blood
Blood (2005) 105 (7): 2862–2868.
https://doi.org/10.1182/blood-2004-06-2410
Published: 2005
Includes: Supplemental data
Journal Articles

Role of trans -cellular IL-15 presentation in the activation of NK cell–mediated killing, which leads to enhanced tumor immunosurveillance

Hisataka Kobayashi, Sigrid Dubois, Noriko Sato, Helen Sabzevari, Yoshio Sakai, Thomas A. Waldmann, Yutaka Tagaya
Journal: Blood
Blood (2005) 105 (2): 721–727.
https://doi.org/10.1182/blood-2003-12-4187
Published: 2005