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Journal Articles

Efficacy and Safety of Emicizumab Prophylaxis in Patients with Acquired Hemophilia a Who Were Deemed Ineligible for Immunosuppressive Therapy: Additional Data from the Ageha Study

Hidekazu Nishikii, Nobuaki Suzuki, Ryota Kobayashi, Narumi Mizuno, Ryoto Ozaki, Midori Shima

Blood (2022) 140 (Supplement 1): 2724–2725.

https://doi.org/10.1182/blood-2022-162237

Published: 2022

Journal Articles

Tumor Necrosis Factor from Leukemic Microenvironment Provides Non-Leukemic Hematopoietic Stem Cells with Megakaryocyte Lineage Bias

Hidekazu Nishikii, Mizuki Saito, Takaharu Kimura, Yusuke Kiyoki, Takayasu Kato, Tatsuhiro Sakamoto, Mamiko Sakata-Yanagimoto, Naoshi Obara, Satoshi Yamazaki, Shigeru Chiba

Blood (2022) 140 (Supplement 1): 5774–5775.

https://doi.org/10.1182/blood-2022-162978

Published: 2022

Journal Articles

Elongation of Long-Chain Fatty Acids Is Crucial for Hematopoietic Stem Cell Engraftment and Leukemia Propagation

Takayasu Kato, Yusuke Kiyoki, Sakura Kito, Takashi Matsuzaka, Shin Morioka, Junko Sasaki, Tatsuhiro Sakamoto, Hidekazu Nishikii, Naoshi Obara, Mamiko Sakata-Yanagimoto, Takehiko Sasaki, Hitoshi Shimano, Shigeru Chiba

Blood (2022) 140 (Supplement 1): 728–729.

https://doi.org/10.1182/blood-2022-165818

Published: 2022

Journal Articles

A Single-Cell Atlas of Nonhematopoietic Cells in Human Lymph Node and Lymphoma Reveals Landscape of Stromal Remodeling

Blood (2021) 138 (Supplement 1): 447.

https://doi.org/10.1182/blood-2021-145718

Published: 2021

Journal Articles

Distinct Bone Marrow Microenvironment Abnormalities in MDS and MPN with Fibrosis

Cao Sy Luan, MS, Yoshiaki Takahoko, MS, Hidekazu Nishikii, MD PhD, Naoshi Obara, MD PhD, Tatsuhiro Sakamoto, MD PhD, Takayasu Kato, MD PhD, Keiichiro Hattori, MD PhD, Ryota Matsuoka, MD PhD, Shingo Sakashita, MD PhD, Yasuhito Nannya, MD PhD, Hideki Makishima, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Seishi Ogawa, MD PhD, Shigeru Chiba, MD PhD

Blood (2019) 134 (Supplement_1): 2976.

https://doi.org/10.1182/blood-2019-129423

Published: 2019

Journal Articles

Liquid Biopsy for the Identification of Intravascular Large B-Cell Lymphoma

Blood (2017) 130 (Supplement 1): 378.

https://doi.org/10.1182/blood.V130.Suppl_1.378.378

Published: 2017

Journal Articles

DR3 signaling modulates the function of Foxp3 + regulatory T cells and the severity of acute graft-versus-host disease

Hidekazu Nishikii, Byung-Su Kim, Yasuhisa Yokoyama, Yan Chen, Jeanette Baker, Antonio Pierini, Maite Alvarez, Melissa Mavers, Kristina Maas-Bauer, Yuqiong Pan, Shigeru Chiba, Robert S. Negrin

Blood (2016) 128 (24): 2846–2858.

https://doi.org/10.1182/blood-2016-06-723783

Published: 2016

Includes: Supplemental data

Journal Articles

Foxp3 + regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells

Hidekazu Nishikii, MD PhD, Antonio Pierini, MD, Yasuhisa Yokoyama, MD,PhD, Takaharu Kimura, MD PhD, Hye-Sook Kwon, PhD, Maite Alvarez, PhD, Jeanette Baker, PhD, Judith Shizuru, MD PhD, Joy Wu, MD PhD, Shigeru Chiba, MD, PhD, Robert S. Negrin, MD

Blood (2016) 128 (22): 431.

https://doi.org/10.1182/blood.V128.22.431.431

Published: 2016

Journal Articles

Notch Signaling in Bone Marrow Nestin-Expressing Cells Controls Balance of Erythropoiesis at the Bone Marrow and Spleen

Tatsuhiro Sakamoto, MD, Naoshi Obara, MDPhD, Takayasu Kato, MD PhD, Luan Cao Sy, Hidekazu Nishikii, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Satoru Takahashi, MDPhD, Shigeru Chiba, MD, PhD

Blood (2016) 128 (22): 432.

https://doi.org/10.1182/blood.V128.22.432.432

Published: 2016

Journal Articles

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

Hidekazu Nishikii, MD PhD, Kim Byung-Su, Yan Chen, MD, Jeanette Baker, PhD, Antonio Pierini, MD, Maite Alvarez, PhD, Melissa Mavers, MD, Kristina Maas-Bauer, MD, Robert S. Negrin, MD

Blood (2016) 128 (22): 2148.

https://doi.org/10.1182/blood.V128.22.2148.2148

Published: 2016

Journal Articles

Abnormal Increase in a Distinct Subset of Nestin-Expressing Cells in the Bone Marrow of Myelodysplastic Syndromes

Luan Cao-Sy, MS, Naoshi Obara, MD PhD, Tatsuhiro Sakamoto, MD, Takayasu Kato, MD PhD, Hidekazu Nishikii, MD, PhD, Mamiko Sakata-Yanagimoto, MD PhD, Shigeru Chiba, MD, PhD

Blood (2016) 128 (22): 3887.

https://doi.org/10.1182/blood.V128.22.3887.3887

Published: 2016

Journal Articles

TNF-α priming enhances CD4 + FoxP3 + regulatory T-cell suppressive function in murine GVHD prevention and treatment

Antonio Pierini, William Strober, Caitlin Moffett, Jeanette Baker, Hidekazu Nishikii, Maite Alvarez, Yuqiong Pan, Dominik Schneidawind, Everett Meyer, Robert S. Negrin

Blood (2016) 128 (6): 866–871.

https://doi.org/10.1182/blood-2016-04-711275

Published: 2016

Includes: Supplemental data

Journal Articles

Expanded CD4+Foxp3+ Regulatory T Cells through DR3 Signaling Have a Distinct Immunophenotype and Abrogate the Lethal Acute-Graft and Host Disease after Allogeneic Transplantation

Hidekazu Nishikii, MD, PhD, Byung-Su Kim, MD, Yasuhisa Yokoyama, MD,PhD, Jeanette Baker, PhD, Antonio Pierini, MD, Maite Alvarez, PhD, Yuqiong Pan, MD, PhD, Yan Chen, MD, Dominik Schneidawind, MD, Shigeru Chiba, MD, PhD, Robert Negrin, MD

Blood (2015) 126 (23): 1876.

https://doi.org/10.1182/blood.V126.23.1876.1876

Published: 2015

Journal Articles

TNF-Alpha Priming Enhances CD4 + FoxP3 + Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment

Antonio Pierini, MD, Caitlin Moffett, Dominik Schneidawind, MD, Jeanette Baker, PhD, Hidekazu Nishikii, MD PhD, Yuqiong Pan, MD, PhD, Maite Alvarez, PhD, Everett Meyer, MD PhD, Robert Negrin, MD

Blood (2015) 126 (23): 1885.

https://doi.org/10.1182/blood.V126.23.1885.1885

Published: 2015

Journal Articles

Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease

Byung-Su Kim, Hidekazu Nishikii, Jeanette Baker, Antonio Pierini, Dominik Schneidawind, Yuqiong Pan, Andreas Beilhack, Chung-Gyu Park, Robert S. Negrin

Blood (2015) 126 (4): 546–557.

https://doi.org/10.1182/blood-2015-04-637587

Published: 2015

Includes: Supplemental data

Journal Articles

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Antonio Pierini, MD, Hidekazu Nishikii, MD PhD, Yuqiong Pan, MD, Jeanette Baker, PhD, Dennis B Leveson-Gower, PhD, Mareike Florek, MD, Robert Negrin, MD

Blood (2014) 124 (21): 4322.

https://doi.org/10.1182/blood.V124.21.4322.4322

Published: 2014

Journal Articles

Activation of DR3 Signaling Expands Recipient Derived Regulatory T Cells and Enhances Donor Immune Reconstitution Derived from Allogeneic Hematopoietic Stem Cells

Hidekazu Nishikii, MD PhD, Byung Su Kim, MD, Antonio Pierini, MD, Jeanette Baker, PhD, Dominik Schneidawind, MD, Yuqiong Pan, MD, Maite Alvarez, PhD, Robert S. Negrin, MD

Blood (2014) 124 (21): 1087.

https://doi.org/10.1182/blood.V124.21.1087.1087

Published: 2014

Journal Articles

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

Antonio Pierini, MD, Hidekazu Nishikii, MD, PhD, Mareike Florek, MD, Dennis B Leveson-Gower, PhD, Yuqiong Pan, MD, Byung-Su Kim, MD, Jeanette Baker, PhD, Robert Negrin, MD

Blood (2013) 122 (21): 1996.

https://doi.org/10.1182/blood.V122.21.1996.1996

Published: 2013

Journal Articles

Hes1 Is Responsible For Notch Signaling-Mediated Suppression Of Acute Myeloid Leukemia Development Via Suppression Of FLT3 Expression

Takayasu Kato, MD, PhD, Mamiko Sakata-Yanagimoto, MD, PhD, Hidekazu Nishikii, MD, PhD, Yasuyuki Miyake, Yasuhisa Yokoyama, MD, Yukitugu Asabe, Naoshi Obara, MD, PhD, Kazumi Suzukawa, MD, PhD, Ryoichiro Kageyama, MD, PhD, Shigeru Chiba, MD, PhD

Blood (2013) 122 (21): 3800.

https://doi.org/10.1182/blood.V122.21.3800.3800

Published: 2013

Journal Articles

Agonistic Anti-DR3 Antibody Expands Treg and Reduces Experimental Acute Graft-Versus-Host Disease

Byung-Su Kim, MD, Antonio Pierini, MD, Dominik Schneidawind, MD, Jeanette Baker, PhD, Hidekazu Nishikii, MD, PhD, Yuqiong Pan, MD, Maite Alvarez, PhD, Robert Negrin, MD

Blood (2013) 122 (21): 135.

https://doi.org/10.1182/blood.V122.21.135.135

Published: 2013

NARROW

Efficacy and Safety of Emicizumab Prophylaxis in Patients with Acquired Hemophilia a Who Were Deemed Ineligible for Immunosuppressive Therapy: Additional Data from the Ageha Study

Tumor Necrosis Factor from Leukemic Microenvironment Provides Non-Leukemic Hematopoietic Stem Cells with Megakaryocyte Lineage Bias

Elongation of Long-Chain Fatty Acids Is Crucial for Hematopoietic Stem Cell Engraftment and Leukemia Propagation

A Single-Cell Atlas of Nonhematopoietic Cells in Human Lymph Node and Lymphoma Reveals Landscape of Stromal Remodeling

Distinct Bone Marrow Microenvironment Abnormalities in MDS and MPN with Fibrosis

Liquid Biopsy for the Identification of Intravascular Large B-Cell Lymphoma

DR3 signaling modulates the function of Foxp3 + regulatory T cells and the severity of acute graft-versus-host disease

Foxp3 + regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells

Notch Signaling in Bone Marrow Nestin-Expressing Cells Controls Balance of Erythropoiesis at the Bone Marrow and Spleen

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

Abnormal Increase in a Distinct Subset of Nestin-Expressing Cells in the Bone Marrow of Myelodysplastic Syndromes

TNF-α priming enhances CD4 + FoxP3 + regulatory T-cell suppressive function in murine GVHD prevention and treatment

Expanded CD4+Foxp3+ Regulatory T Cells through DR3 Signaling Have a Distinct Immunophenotype and Abrogate the Lethal Acute-Graft and Host Disease after Allogeneic Transplantation

TNF-Alpha Priming Enhances CD4 + FoxP3 + Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment

Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease

CD4+FoxP3+ Regulatory T Cells Regulate B Cell Differentiation and Induce Tolerance to Bone Marrow Grafts

Activation of DR3 Signaling Expands Recipient Derived Regulatory T Cells and Enhances Donor Immune Reconstitution Derived from Allogeneic Hematopoietic Stem Cells

Host CD4+CD25+FoxP3+ Regulatory T Cells Facilitate Donor Engraftment Without Impacting Graft Versus Host Disease Onset After Major-Mismatched Hematopoietic Stem Cell Transplantation

Hes1 Is Responsible For Notch Signaling-Mediated Suppression Of Acute Myeloid Leukemia Development Via Suppression Of FLT3 Expression

Agonistic Anti-DR3 Antibody Expands Treg and Reduces Experimental Acute Graft-Versus-Host Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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