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Journal Articles

Acalabrutinib in Combination with Venetoclax and Obinutuzumab or Rituximab in Patients with Treatment-Naïve or Relapsed/Refractory Chronic Lymphocytic Leukemia

Jennifer A. Woyach, MD, James S. Blachly, MD, Kerry A. Rogers, MD, Seema A Bhat, MD, Michael R. Grever, MD, Adam S. Kittai, MD, Mojgan Jianfar, MD, Gerard Lozanski, MD, David M. Weiss, Barbara L. Andersen, PhD, Priti Patel, MD, Veerendra Munugalavadla, PhD, Anna Butturini, MD, Yan Xu, Min Hui Wang, PhD, John C. Byrd, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–18.
https://doi.org/10.1182/blood-2020-136317
Published: 2020
Journal Articles

ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Jeff P. Sharman, MD, Versha Banerji, MD, Laura Maria Fogliatto, MD PhD, Yair Herishanu, MD, Talha Munir, MD, Renata Walewska, George Follows, Karin Karlsson, MD, Paolo Ghia, MD PhD, Gillian Corbett, Patricia Walker, MBBS, Miklos Egyed, Wojciech Jurczak, MD PhD, Gilles Salles, MD PhD, Ann Janssens, Florence Cymbalista, MD PhD, William G. Wierda, MD PhD, Steven Coutre, MD, John M. Pagel, MD PhD DSc, Alan Skarbnik, MD, Manali Kamdar, MD, Jennifer Woyach, MD, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Priti Patel, MD, Min Hui Wang, PhD, Sofia Wong, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 31.
https://doi.org/10.1182/blood-2019-128404
Published: 2019
Journal Articles

Acalabrutinib Monotherapy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: 42-Month Follow-up of a Phase 2 Study

Richard R. Furman, MD, William G. Wierda, MD PhD, Anna Schuh, Stephen Devereux, PhD, Jorge M. Chaves, MD, Jennifer R. Brown, MD PhD, Peter Hillmen, MD PhD, Peter Martin, FRCPC, MD MS, Farrukh T Awan, MD, Deborah M. Stephens, DO, Paolo Ghia, MD PhD, Jacqueline C. Barrientos, MD MS, John M. Pagel, MD PhD DSc, Jennifer Woyach, MD, Kathleen Burke, PhD, Todd Covey, Michael Gulrajani, Ahmed Hamdy, MD, Raquel Izumi, PhD, Melanie M. Frigault, PhD, Priti Patel, MD, Wayne Rothbaum, Min Hui Wang, PhD, Susan M. O'Brien, MD, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3039.
https://doi.org/10.1182/blood-2019-128706
Published: 2019
Journal Articles

A Phase 3 Trial Comparing the Efficacy and Safety of Acalabrutinib in Combination with Venetoclax with or without Obinutuzumab, Compared with Investigator's Choice of Chemoimmunotherapy in Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL) without Del(17p) or TP53 Mutation

Jennifer R Brown, MD PhD, Barbara F. Eichhorst, MD, Paolo Ghia, MD PhD, Arnon P. Kater, MD PhD, Jianyong Li, MD, Sudha Khurana, Mostafa Elhamy, Min Hui Wang, PhD, John F. Seymour, MBBS, PhD FRACP
Journal: Blood
Blood (2019) 134 (Supplement_1): 4318.
https://doi.org/10.1182/blood-2019-123057
Published: 2019
Journal Articles

CD19-CAR-T Therapy Followed By Allogeneic Hematopoietic Stem Cell Transplantation in Refractory/Relapsed and High Risk B-Cell Acute Lymphoblastic Leukemia

Yanli Zhao, Jianping Zhang, Deyan Liu, Min Xiong, Zhijie Wei, Ruijuan Sun, Jiarui Zhou, Yue Lu, Xingyu Cao, Junfang Yang, MD, Xian Zhang, PhD, Hui Wang, PhD, Hongxing Liu, MD, Peihua Lu, Daopei Lu
Journal: Blood
Blood (2018) 132 (Supplement 1): 2660.
https://doi.org/10.1182/blood-2018-99-118852
Published: 2018
Journal Articles

Acalabrutinib in Treatment-Naive (TN) Chronic Lymphocytic Leukemia (CLL): Updated Results from the Phase 1/2 ACE-CL-001 Study

John C. Byrd, MD, Jennifer A. Woyach, MD, Richard R. Furman, MD, Peter Martin, FRCPC, MD MS, Susan M. O'Brien, MD, Jennifer R. Brown, MD PhD, Deborah M. Stephens, Jacqueline C. Barrientos, MD, Stephen Devereux, PhD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, John M. Pagel, MD PhD, Dih-Yih Chen, MD, Ahmed Hamdy, MD, Raquel Izumi, PhD, Priti Patel, MD, Min Hui Wang, PhD, Nitin Jain, MD, William G. Wierda, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 692.
https://doi.org/10.1182/blood-2018-99-110451
Published: 2018
Journal Articles

Positive Stool Cultures Could Predict the Clinical Outcomes of Haploidentical Hematopoietic Stem Cell Transplantation

Lijuan Hu, Qi Wang, PhD, Xiaohui Zhang, Lan-Ping Xu, MD, Yu Wang, Chen-Hua Yan, Huan Chen, Yu-Hong Chen, Kaiyan Liu, MD PhD, Hui Wang, PhD, Xiaojun Huang, MD, Xiao-Dong Mo
Journal: Blood
Blood (2018) 132 (Supplement 1): 5757.
https://doi.org/10.1182/blood-2018-99-109858
Published: 2018
Journal Articles

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

Anna M Paczulla, PhD, Kathrin Rothfelder, PhD, Simon Raffel, MD, Martina Konantz, PhD, Julia Steinbacher, PhD, Hui Wang, PhD, Marcelle Ndoh Mbarga, Thorsten Schaefer, PhD, Daniela Dörfel, MD, Mattia Falcone, Eva Nievergall, PhD, Claudia Tandler, MSc, Christoph Lutz, Pontus Lundberg, PhD, Lothar Kanz, Leticia Quintanilla-Martinez, MD, Alexander Steinle, Andreas Trumpp, Prof, PhD, Helmut R. Salih, MD, Claudia Lengerke, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 769.
https://doi.org/10.1182/blood-2018-99-118047
Published: 2018
Journal Articles

Acalabrutinib with Obinutuzumab in Relapsed/Refractory and Treatment-Naive Patients with Chronic Lymphocytic Leukemia: The Phase 1b/2 ACE-CL-003 Study

Jennifer A. Woyach, MD, Farrukh T. Awan, MD MS, Mojgan Jianfar, MD, Kerry A. Rogers, MD, Jeffrey Jones, MD MPH, Todd Covey, PhD, Ahmed Hamdy, MD, Raquel Izumi, PhD, Priti Patel, MD, Min Hui Wang, PhD, John C. Byrd, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 432.
https://doi.org/10.1182/blood.V130.Suppl_1.432.432
Published: 2017
Journal Articles

Acalabrutinib Monotherapy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Updated Results from the Phase 1/2 ACE-CL-001 Study

John C. Byrd, MD, William G Wierda, MD PhD, Anna Schuh, MD PhD, Stephen Devereux, FRCP, FRCPath, PhD, Jorge M. Chaves, MD, Jennifer R. Brown, MD PhD, Peter Hillmen, MBChB, PhD, Peter Martin, MD, Farrukh T. Awan, MD MS, Deborah M. Stephens, DO, Paolo Ghia, MD PhD, Jacqueline C. Barrientos, MD, John M. Pagel, MD PhD, Jennifer A. Woyach, MD, Prista Charuworn, MD, Ahmed Hamdy, MD, Raquel Izumi, PhD, Priti Patel, MD, Wayne M. Rothbaum, Min Hui Wang, PhD, Richard R. Furman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 498.
https://doi.org/10.1182/blood.V130.Suppl_1.498.498
Published: 2017
Journal Articles

The Bruton Tyrosine Kinase (Btk) Inhibitor ACP-196: Marked Activity in Relapsed/Refractory CLL with a Favorable Safety Profile

John C. Byrd, MD, William Wierda, MD PhD, Jeffrey Jones, MD MPH, Susan O'Brien, MD, Jennifer R. Brown, MD PhD, Anna Schuh, MD PhD, Peter Hillmen, MB, ChB, PhD, Deborah M. Stephens, DO, Paolo Ghia, MD PhD, Steve Devereux, MD, Jorge M. Chaves, MD, Jacqueline C. Barrientos, MD, Min Hui Wang, PhD, Jane Huang, MD, Todd Covey, Tasheda Navarro, Wayne Rothbaum, Raquel Izumi, PhD, Ahmed Hamdy, MBBCh, Richard R. Furman, MD
Journal: Blood
Blood (2015) 126 (23): 831.
https://doi.org/10.1182/blood.V126.23.831.831
Published: 2015
Journal Articles

Association Between Down-Regulation of EZH2 and Abnormal Karyotype, Response to Hypomethylation Treatment, and Patient Survival in Myelodysplastic Syndromes

Yue Wei, Monica Cabrero, MD, Yu Jia, Hong Zheng, Hui Yang, MD, PhD, Zhihong Fang, Zach Bohannan, Rui Chen, PhD, Hui Wang, PhD, Simona Colla, Xia Wang, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2014) 124 (21): 3241.
https://doi.org/10.1182/blood.V124.21.3241.3241
Published: 2014
Journal Articles

Elotuzumab in Combination with Lenalidomide and Low-Dose Dexamethasone in High-Risk and/or Stage 23 Relapsed and/or Refractory Multiple Myeloma: A Retrospective Subset Analysis of the Phase 2 Study,

Sundar Jagannath, MD, Sagar Lonial, MD, Andrzej J Jakubowiak, MD, Thierry Facon, MD, Ravi Vij, MD, Marc S Raab, MD, PhD, Darrell J. White, MD, Min-Hui Wang, PhD, Teresa Parli, MD, Blake J Bartlett, PhD, Anil K Singhal, MD, Paul G. Richardson, MD
Journal: Blood
Blood (2011) 118 (21): 3968.
https://doi.org/10.1182/blood.V118.21.3968.3968
Published: 2011
Journal Articles

Genome-Wide Chip-Seq Analysis of Histone Methylation Reveals Modulators of NF-κB Signaling and the Histone Demethylase JMJD3 as Implicated in Disease Progression in Myelodysplastic Syndrome (MDS).

Yue Wei, PhD, Rui Chen, PhD, Carlos E. Bueso-Ramos, MD, Hui Wang, PhD, Xingzhi Song, PhD, Jing Wang, Hui Yao, Martin Nguyen, Michael Fernandez, Hui Yang, MD, PhD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2009) 114 (22): 291.
https://doi.org/10.1182/blood.V114.22.291.291
Published: 2009
Journal Articles

The Effects of Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Monoclonal Antibodies (mAb) Against 11q23 Positive Acute Leukemia Cells.

Allison S. Drake, MS, Brady T. Michael, BS, Xin Hui Wang, PhD, Sheila J.N. Sait, PhD, Justin C. Earp, William J. Jusko, PhD, Soldano Ferrone, MD, PhD, Eunice S. Wang, MD, Meir Wetzler, MD
Journal: Blood
Blood (2006) 108 (11): 4550.
https://doi.org/10.1182/blood.V108.11.4550.4550
Published: 2006